Matt J Neville

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1
    Matt J Neville
    Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, UK
    Hum Mutat 23:540-5. 2004
  2. ncbi Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma
    Ulf Riserus
    Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, OX3 7LJ, UK
    Diabetes 54:1379-84. 2005
  3. pmc Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes
    Josine L Min
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    PLoS Genet 8:e1002505. 2012
  4. pmc Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans
    Katherine E Pinnick
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Diabetes 61:1399-403. 2012
  5. pmc MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven
    Mattias Rantalainen
    Department of Statistics, University of Oxford, Oxford, United Kingdom
    PLoS ONE 6:e27338. 2011
  6. doi Comprehensive human adipose tissue mRNA and microRNA endogenous control selection for quantitative real-time-PCR normalization
    Matt J Neville
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
    Obesity (Silver Spring) 19:888-92. 2011
  7. doi The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease
    Aaron J Trachtenberg
    Functional Magnetic Resonance Imaging of the Brain FMRIB Centre, University of Oxford, Department of Clinical Neurology, John Radcliffe Hospital, Headington, Oxford, UK
    Neurobiol Aging 33:618.e1-618.e13. 2012
  8. pmc De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation
    Jennifer M Collins
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom
    J Lipid Res 52:1683-92. 2011
  9. ncbi Absence of relationship between MTTP haplotypes and longevity
    Matt J Neville
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK
    J Gerontol A Biol Sci Med Sci 62:202-5. 2007
  10. ncbi Identification of CYP2B6 sequence variants by use of multiplex PCR with allele-specific genotyping
    Robyn M Jacob
    Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, United Kingdom
    Clin Chem 50:1372-7. 2004

Collaborators

Detail Information

Publications12

  1. ncbi Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1
    Matt J Neville
    Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, UK
    Hum Mutat 23:540-5. 2004
    ..If this is the case, then changes in ANKK1 activity may provide an alternative explanation for previously described associations between the DRD2 Taq1A RFLP and neuropsychiatric disorders such as addiction...
  2. ncbi Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma
    Ulf Riserus
    Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, OX3 7LJ, UK
    Diabetes 54:1379-84. 2005
    ..The restored SCD activity index after rosiglitazone in PPARgamma mutation supports a pivotal role of PPARgamma function in SCD regulation...
  3. pmc Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes
    Josine L Min
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    PLoS Genet 8:e1002505. 2012
    ....
  4. pmc Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans
    Katherine E Pinnick
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Diabetes 61:1399-403. 2012
    ..Moreover, this appears to be an inherent feature of gluteofemoral AT. We propose that the beneficial metabolic properties of lower-body AT may be partly explained by the intrinsically greater production and release of palmitoleate...
  5. pmc MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven
    Mattias Rantalainen
    Department of Statistics, University of Oxford, Oxford, United Kingdom
    PLoS ONE 6:e27338. 2011
    ....
  6. doi Comprehensive human adipose tissue mRNA and microRNA endogenous control selection for quantitative real-time-PCR normalization
    Matt J Neville
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
    Obesity (Silver Spring) 19:888-92. 2011
    ..This test clearly indicated that spurious results could arise from using less stable control transcripts for mRNA and microRNA qRT-PCR...
  7. doi The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease
    Aaron J Trachtenberg
    Functional Magnetic Resonance Imaging of the Brain FMRIB Centre, University of Oxford, Department of Clinical Neurology, John Radcliffe Hospital, Headington, Oxford, UK
    Neurobiol Aging 33:618.e1-618.e13. 2012
    ..These results question the often assumed link between APOE, the blood oxygenation level dependent (BOLD) response, and AD risk...
  8. pmc De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation
    Jennifer M Collins
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom
    J Lipid Res 52:1683-92. 2011
    ..DNL in human fat cells is tightly coupled with further modification of fatty acids to produce a range of saturated and unsaturated fatty acids consistent with normal maturation...
  9. ncbi Absence of relationship between MTTP haplotypes and longevity
    Matt J Neville
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK
    J Gerontol A Biol Sci Med Sci 62:202-5. 2007
    ..However, the association of MTTP with longevity has been contested in a large German collection of nonagenarians and centenarians...
  10. ncbi Identification of CYP2B6 sequence variants by use of multiplex PCR with allele-specific genotyping
    Robyn M Jacob
    Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, United Kingdom
    Clin Chem 50:1372-7. 2004
    ..The aim of the present study was to develop a reliable and robust assay for determining genotypic variants...
  11. doi Proteomic analysis of human adipose tissue after rosiglitazone treatment shows coordinated changes to promote glucose uptake
    Meftun Ahmed
    Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Obesity (Silver Spring) 18:27-34. 2010
    ..Such orchestrated changes in expression of multiple proteins provide insights into the mechanism underlying the increased efficiency in glucose uptake and improvement of insulin sensitivity in response to rosiglitazone treatment...
  12. ncbi Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1
    Jin Hong Low
    Gastroenterology Unit, Gibson Laboratories, Radcliffe Infirmary, University of Oxford, Oxford, UK
    Inflamm Bowel Dis 10:173-81. 2004
    ..7% vs 64.7%, Pc = 0.0040). These data support linkage for CD at 19p13 and suggest that the amino acid polymorphisms in ICAM-1 may be associated with IBD...