Z S Nagy

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Cell cycle-related protein expression in Alzheimer's disease and vascular disease
    Zsuzsanna Nagy
    OPTIMA, University of Oxford, Oxford, UK
    Int Psychogeriatr 15:77-9. 2003
  2. ncbi Staging of Alzheimer-type pathology: an interrater-intrarater study
    Z Nagy
    Department of Neuropathology, University of Oxford, UK
    Dement Geriatr Cogn Disord 8:248-51. 1997
  3. ncbi Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions
    Z Nagy
    OPTIMA, Radcliffe Infirmary, Oxford, UK
    Acta Neuropathol 93:294-300. 1997
  4. ncbi Cell cycle kinesis in lymphocytes in the diagnosis of Alzheimer's disease
    Zsuzsanna Nagy
    OPTIMA, Department of Neuropathology, Radcliffe Infirmary NHS Trust, University of Oxford, Woodstock Road, Oxford OX2 6HE, UK
    Neurosci Lett 317:81-4. 2002
  5. ncbi Cell cycle regulatory failure in neurones: causes and consequences
    Z Nagy
    OPTIMA, Departments of Neuropathology and Pharmacology, University of Oxford, Radcliffe Infirmary NHS Trust, Woodstock Road, OX2 6HE, Oxford, UK
    Neurobiol Aging 21:761-9. 2000
  6. ncbi Mechanisms of neuronal death in Down's syndrome
    Z Nagy
    Department of Neuropathology, University of Oxford, United Kingdom
    J Neural Transm Suppl 57:233-45. 1999
  7. ncbi Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology
    Z Nagy
    OPTIMA, Department of Neuropathology, University of Oxford, UK
    Acta Neuropathol 97:346-54. 1999
  8. ncbi The progression of Alzheimer's disease from limbic regions to the neocortex: clinical, radiological and pathological relationships
    Z Nagy
    OPTIMA, Departments of Pharmacology and Neuropathology, Department of Pharmacology, University of Oxford, UK
    Dement Geriatr Cogn Disord 10:115-20. 1999
  9. ncbi Accuracy of clinical operational diagnostic criteria for Alzheimer's disease in relation to different pathological diagnostic protocols
    Z Nagy
    OPTIMA, Department of Neuropathology, University of Oxford, UK
    Dement Geriatr Cogn Disord 9:219-26. 1998
  10. ncbi Cell cycle markers in the hippocampus in Alzheimer's disease
    Z Nagy
    OPTIMA, Department of Neuropathology and Pharmacology, University of Oxford, UK
    Acta Neuropathol 94:6-15. 1997

Collaborators

Detail Information

Publications19

  1. ncbi Cell cycle-related protein expression in Alzheimer's disease and vascular disease
    Zsuzsanna Nagy
    OPTIMA, University of Oxford, Oxford, UK
    Int Psychogeriatr 15:77-9. 2003
    ..In this context the role of shared risk factors, such as ApoE and elevated plasma homocysteine, is also discussed...
  2. ncbi Staging of Alzheimer-type pathology: an interrater-intrarater study
    Z Nagy
    Department of Neuropathology, University of Oxford, UK
    Dement Geriatr Cogn Disord 8:248-51. 1997
    ..This makes it suitable for brain-banking and research purposes...
  3. ncbi Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions
    Z Nagy
    OPTIMA, Radcliffe Infirmary, Oxford, UK
    Acta Neuropathol 93:294-300. 1997
    ..The absence of nuclear pCNA or p53 suggests that the cycle is arrested in G1. The significance of our findings and their relationship to the production of neurodegenerative cell death via an apoptotic mechanism are discussed...
  4. ncbi Cell cycle kinesis in lymphocytes in the diagnosis of Alzheimer's disease
    Zsuzsanna Nagy
    OPTIMA, Department of Neuropathology, Radcliffe Infirmary NHS Trust, University of Oxford, Woodstock Road, Oxford OX2 6HE, UK
    Neurosci Lett 317:81-4. 2002
    ..We propose that the introduction of the test could be useful in identifying people who do not yet fulfil the requirements of the NINCDS criteria for dementia, but who would benefit from the use of preventive measures for AD...
  5. ncbi Cell cycle regulatory failure in neurones: causes and consequences
    Z Nagy
    OPTIMA, Departments of Neuropathology and Pharmacology, University of Oxford, Radcliffe Infirmary NHS Trust, Woodstock Road, OX2 6HE, Oxford, UK
    Neurobiol Aging 21:761-9. 2000
    ..On the other hand we can only speculate on the mechanisms that lead to the subsequent regulatory failure...
  6. ncbi Mechanisms of neuronal death in Down's syndrome
    Z Nagy
    Department of Neuropathology, University of Oxford, United Kingdom
    J Neural Transm Suppl 57:233-45. 1999
    ..Subsequently the cell cycle arrest may lead to either the formation of Alzheimer-related pathology or to apoptotic cell death...
  7. ncbi Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology
    Z Nagy
    OPTIMA, Department of Neuropathology, University of Oxford, UK
    Acta Neuropathol 97:346-54. 1999
    ....
  8. ncbi The progression of Alzheimer's disease from limbic regions to the neocortex: clinical, radiological and pathological relationships
    Z Nagy
    OPTIMA, Departments of Pharmacology and Neuropathology, Department of Pharmacology, University of Oxford, UK
    Dement Geriatr Cogn Disord 10:115-20. 1999
    ..The additive effect of pathologies co-existing with AD is apparent in reduced cognitive scores, while the atrophy of limbic structures, as measured on CT scans, seems to be mainly attributable to AD-related pathology...
  9. ncbi Accuracy of clinical operational diagnostic criteria for Alzheimer's disease in relation to different pathological diagnostic protocols
    Z Nagy
    OPTIMA, Department of Neuropathology, University of Oxford, UK
    Dement Geriatr Cogn Disord 9:219-26. 1998
    ..This makes the use of these categories suitable for research purposes. However, the negative predictive value of both diagnoses is poor (33-63%), making these criteria unsuitable for diagnostic purposes in clinical practice...
  10. ncbi Cell cycle markers in the hippocampus in Alzheimer's disease
    Z Nagy
    OPTIMA, Department of Neuropathology and Pharmacology, University of Oxford, UK
    Acta Neuropathol 94:6-15. 1997
    ..Since factors known to be present in G2 seem to be responsible for microtubule destabilisation and hyperphosphorylation of tau we hypothesise that cell cycle disturbances may be important in the pathogenesis of AD...
  11. ncbi Apoptosis-related protein expression in the hippocampus in Alzheimer's disease
    Z S Nagy
    OPTIMA, Department of Neuropathology, University of Oxford, United Kingdom
    Neurobiol Aging 18:565-71. 1997
    ..Double labeling studies indicated that AT8-positive cells and neurites were never Bax-positive and vice versa. The possible implications of the different expression patterns are discussed in relation to neurone death in AD...
  12. ncbi Neuronal cyclin expression in the hippocampus in temporal lobe epilepsy
    Z Nagy
    OPTIMA, Department of Neuropathology and Department of Pharmacology, University of Oxford, Oxford, United Kingdom
    Exp Neurol 150:240-7. 1998
    ..We interpret these neuronal findings as evidence of cell cycle disturbances and a possible apoptotic mechanism of hippocampal neuronal cell death in TLE...
  13. ncbi Assessment of the pathological stages of Alzheimer's disease in thin paraffin sections: a comparative study
    Z Nagy
    OPTIMA, Department of Neuropathology, University of Oxford, UK
    Dement Geriatr Cogn Disord 9:140-4. 1998
    ..We conclude that the adapted staging method in thin sections is strongly reliable and we recommend it for staging purposes in institutions where the preparation of thick sections would be difficult...
  14. ncbi Depressive symptoms increase the likelihood of cognitive impairment in elderly people with subclinical Alzheimer pathology
    Elizabeth J Milwain
    OPTIMA, Department of Pharmacology, University of Oxford, Oxford, UK
    Dement Geriatr Cogn Disord 19:46-50. 2005
    ..Treating the depressive symptoms would benefit the patient, but the cognitive improvement may not indicate that AD is absent...
  15. ncbi The last neuronal division: a unifying hypothesis for the pathogenesis of Alzheimer's disease
    Zsuzsanna Nagy
    Neuroscience Division Medical School, University of Birmingham, Birmingham, B15 2TT, UK
    J Cell Mol Med 9:531-41. 2005
    ..These views shape the Alzheimer field currently and some will hopefully one day shape the diagnostic and therapeutic approaches to the disease...
  16. ncbi Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse study
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, Maine, USA
    Psychosom Med 68:547-54. 2006
    ....
  17. ncbi The dysregulation of the cell cycle and the diagnosis of Alzheimer's disease
    Zsuzsanna Nagy
    Neuroscience Division, Medical School, University of Birmingham, Birmingham B15 2TT, UK
    Biochim Biophys Acta 1772:402-8. 2007
    ..It is imperative therefore that we find early biomarkers for sporadic Alzheimer's disease, which could identify patients before substantial pathology develops...
  18. pmc Alpha-synuclein pathology in the olfactory pathways of dementia patients
    Paul S Hubbard
    Division of Neuroscience, The Medical School, University of Birmingham, UK
    J Anat 211:117-24. 2007
    ..Furthermore, the results presented here provide further evidence supporting the possible value of a smell test to aid the clinical diagnosis of neurodegenerative diseases...
  19. ncbi Homocysteine and cognitive performance: modification by the ApoE genotype
    Merrill F Elias
    Department of Psychology, University of Maine, Orono, ME 04469, USA
    Neurosci Lett 430:64-9. 2008
    ..Presence of the ApoE-epsilon4 allele modifies the relation between plasma homocysteine and cognitive performance...