Frederick W Muskett

Summary

Affiliation: University of Leicester
Country: UK

Publications

  1. ncbi NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4
    Lorna C Waters
    Department of Biochemistry, Henry Wellcome Building, University of Leicester, Lancaster Road, Leicester, LE1 9HN, U.K
    J Biomol NMR 36:18. 2006
  2. ncbi Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins
    Frederick W Muskett
    MRC Biomedical NMR Centre, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom
    Biochemistry 42:15139-47. 2003
  3. ncbi Solution structure of ZASP PDZ domain; implications for sarcomere ultrastructure and enigma family redundancy
    Yunghan Au
    National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, United Kingdom
    Structure 12:611-22. 2004
  4. ncbi Solution structure of a novel chromoprotein derived from apo-neocarzinostatin and a synthetic chromophore
    Michael D Urbaniak
    Centre for Biomolecular Design and Drug Development, CPES, University of Sussex, Falmer, Lewes Road, Brighton BN1 9QJ, U.K
    Biochemistry 41:11731-9. 2002
  5. ncbi Synthetic ligands for apo-neocarzinostatin
    Stephen Caddick
    Department of Chemistry, University College London, UK
    J Am Chem Soc 128:4204-5. 2006
  6. ncbi Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic
    James R Baker
    University College London, Department of Chemistry, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ, UK
    Chembiochem 8:704-17. 2007

Collaborators

  • Felicity E B May
  • James Feeney
  • Remo Guerrini
  • Stephen Caddick
  • Derek N Woolfson
  • Michael D Urbaniak
  • James R Baker
  • Rhys G Stoneman
  • Lorna C Waters
  • Yunghan Au
  • Thomas A Frenkiel
  • Geoffrey P Kelly
  • Mark D Carr
  • Andrew Prescott
  • Vaclav Veverka
  • Nuvjeevan S Dosanjh
  • Karl-Heinz Klempnauer
  • Catherine Joseph
  • Georgine Faulkner
  • Geoff Kelly
  • Steven R Martin
  • Annalisa Pastore
  • R Andrew Atkinson
  • Alberto Pallavicini
  • Michael D Finucane

Detail Information

Publications6

  1. ncbi NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4
    Lorna C Waters
    Department of Biochemistry, Henry Wellcome Building, University of Leicester, Lancaster Road, Leicester, LE1 9HN, U.K
    J Biomol NMR 36:18. 2006
  2. ncbi Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins
    Frederick W Muskett
    MRC Biomedical NMR Centre, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom
    Biochemistry 42:15139-47. 2003
    ..Such differences have significant implications for the mechanism of action and functional specificity for the TFF class of proteins...
  3. ncbi Solution structure of ZASP PDZ domain; implications for sarcomere ultrastructure and enigma family redundancy
    Yunghan Au
    National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, United Kingdom
    Structure 12:611-22. 2004
    ..ZASP PDZ structure was used to model other members of the enigma family by homology and to predict their abilities to bind alpha-actinin-2...
  4. ncbi Solution structure of a novel chromoprotein derived from apo-neocarzinostatin and a synthetic chromophore
    Michael D Urbaniak
    Centre for Biomolecular Design and Drug Development, CPES, University of Sussex, Falmer, Lewes Road, Brighton BN1 9QJ, U.K
    Biochemistry 41:11731-9. 2002
    ..The clinical use of the natural complex described by others, together with the results reported here, suggests potential applications for small molecule binding by apo-Neocarzinostatin...
  5. ncbi Synthetic ligands for apo-neocarzinostatin
    Stephen Caddick
    Department of Chemistry, University College London, UK
    J Am Chem Soc 128:4204-5. 2006
    ..This work indicates that apo-Neocarzinostatin has multiple selective and distinct binding modes for small-molecule cargo...
  6. ncbi Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic
    James R Baker
    University College London, Department of Chemistry, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ, UK
    Chembiochem 8:704-17. 2007
    ..These investigations hold great promise for the application of the apoproteins for drug-delivery, transport and stabilisation systems...