Graham K Murray

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Infant developmental milestones and subsequent cognitive function
    Graham K Murray
    Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    Ann Neurol 62:128-36. 2007
  2. ncbi request reprint Psychotic symptoms in young people without psychotic illness: mechanisms and meaning
    Graham K Murray
    Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    Br J Psychiatry 201:4-6. 2012
  3. pmc Reinforcement and reversal learning in first-episode psychosis
    G K Murray
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Schizophr Bull 34:848-55. 2008
  4. pmc The neural underpinnings of associative learning in health and psychosis: how can performance be preserved when brain responses are abnormal?
    Graham K Murray
    Brain Mapping Unit, University of Cambridge, Box 189, Cambridge CB2 0QQ, UK
    Schizophr Bull 36:465-71. 2010
  5. pmc Substantia nigra/ventral tegmental reward prediction error disruption in psychosis
    G K Murray
    Brain Mapping Unit, Department of Psychiatry, Addenbrooke s Hospital, University of Cambridge, Cambridge, UK
    Mol Psychiatry 13:239, 267-76. 2008
  6. ncbi request reprint Infant motor development is associated with adult cognitive categorisation in a longitudinal birth cohort study
    G K Murray
    Department of Psychiatry, University of Cambridge, UK, and Muurola Hospital, Hospital District of Lapland, Finland
    J Child Psychol Psychiatry 47:25-9. 2006
  7. ncbi request reprint Infant motor development and adult cognitive functions in schizophrenia
    G K Murray
    Department of Psychiatry, University of Cambridge, UK
    Schizophr Res 81:65-74. 2006
  8. pmc Incentive motivation in first-episode psychosis: a behavioural study
    Graham K Murray
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, UK
    BMC Psychiatry 8:34. 2008
  9. pmc Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort
    Sari Mukkala
    Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, Oulu, Finland
    J Clin Exp Neuropsychol 33:385-94. 2011
  10. ncbi request reprint Schizophrenia in the offspring of antenatally depressed mothers in the northern Finland 1966 birth cohort: relationship to family history of psychosis
    Pirjo Maki
    Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, P O Box 5000, FIN 90014 Oulu, Finland
    Am J Psychiatry 167:70-7. 2010

Detail Information

Publications31

  1. pmc Infant developmental milestones and subsequent cognitive function
    Graham K Murray
    Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    Ann Neurol 62:128-36. 2007
    ..We hypothesized that earlier attainment of developmental milestones would be associated with better subsequent intellectual performance throughout the range of abilities, rather than confined to extremes...
  2. ncbi request reprint Psychotic symptoms in young people without psychotic illness: mechanisms and meaning
    Graham K Murray
    Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    Br J Psychiatry 201:4-6. 2012
    ..Clinicians should be aware that psychotic symptoms in young people are more often associated with common mental disorders such as depression and anxiety than with severe psychotic illness...
  3. pmc Reinforcement and reversal learning in first-episode psychosis
    G K Murray
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Schizophr Bull 34:848-55. 2008
    ..Abnormalities in reinforcement learning and reversal learning have been reported in psychosis, possibly secondary to subcortical dopamine abnormalities...
  4. pmc The neural underpinnings of associative learning in health and psychosis: how can performance be preserved when brain responses are abnormal?
    Graham K Murray
    Brain Mapping Unit, University of Cambridge, Box 189, Cambridge CB2 0QQ, UK
    Schizophr Bull 36:465-71. 2010
    ..The findings suggest that a combination of these factors may resolve the question of why performance is sometimes preserved when brain patterns are disrupted...
  5. pmc Substantia nigra/ventral tegmental reward prediction error disruption in psychosis
    G K Murray
    Brain Mapping Unit, Department of Psychiatry, Addenbrooke s Hospital, University of Cambridge, Cambridge, UK
    Mol Psychiatry 13:239, 267-76. 2008
    ..This study provides the first evidence linking abnormal mesolimbic activity, reward learning and psychosis...
  6. ncbi request reprint Infant motor development is associated with adult cognitive categorisation in a longitudinal birth cohort study
    G K Murray
    Department of Psychiatry, University of Cambridge, UK, and Muurola Hospital, Hospital District of Lapland, Finland
    J Child Psychol Psychiatry 47:25-9. 2006
    ..We hypothesised that the age of learning to stand in infancy would be associated with adult executive function and that the association would be apparent throughout the range of abilities, rather than confined to extremes...
  7. ncbi request reprint Infant motor development and adult cognitive functions in schizophrenia
    G K Murray
    Department of Psychiatry, University of Cambridge, UK
    Schizophr Res 81:65-74. 2006
    ..Childhood neuromotor dysfunction is a risk factor for schizophrenia, a disorder in which cognitive deficits are prominent. The relationship between early neurodevelopment and adult cognition in schizophrenia remains unclear...
  8. pmc Incentive motivation in first-episode psychosis: a behavioural study
    Graham K Murray
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, UK
    BMC Psychiatry 8:34. 2008
    ..It has been proposed that there are abnormalities in incentive motivational processing in psychosis, possibly secondary to subcortical dopamine abnormalities, but few empirical studies have addressed this issue...
  9. pmc Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort
    Sari Mukkala
    Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, Oulu, Finland
    J Clin Exp Neuropsychol 33:385-94. 2011
    ..The two risk groups did not differ significantly from controls, but differed from the psychosis group in fine motor function. Neuropsychological impairments were not evident in a non-help-seeking high-risk sample...
  10. ncbi request reprint Schizophrenia in the offspring of antenatally depressed mothers in the northern Finland 1966 birth cohort: relationship to family history of psychosis
    Pirjo Maki
    Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, P O Box 5000, FIN 90014 Oulu, Finland
    Am J Psychiatry 167:70-7. 2010
    ..The authors examined whether maternal antenatal depressed mood increased the risk of schizophrenia and other psychoses among offspring with and without a familial history of psychosis...
  11. pmc No association of COMT (Val158Met) genotype with brain structure differences between men and women
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    PLoS ONE 7:e33964. 2012
    ....
  12. doi request reprint Neuregulin-1 genotype is associated with structural differences in the normal human brain
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Neuroimage 59:2057-61. 2012
    ..These results suggest that this genetic variant may mediate risk for schizophrenia, in part, through its effect on brain structure in these regions...
  13. doi request reprint Association between duration of untreated psychosis and brain morphology in schizophrenia within the Northern Finland 1966 Birth Cohort
    Matti Penttilä
    University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, P O Box 5000, FIN 90014 Oulu, Finland
    Schizophr Res 123:145-52. 2010
    ..Our aim was to analyze the relation between DUP and the brain structure in schizophrenia in the general population, after several years of illness...
  14. pmc Individual differences in psychotic effects of ketamine are predicted by brain function measured under placebo
    Garry D Honey
    Department of Psychiatry, Brain Mapping Unit and Behavioural and Clinical Neurosciences Institute, University of Cambridge, School of Clinical Medicine, Cambridge CB2 2QQ, United Kingdom
    J Neurosci 28:6295-303. 2008
    ..These results demonstrate precise and predictive brain markers for individual profiles of vulnerability to drug-induced psychosis...
  15. pmc Fronto-cerebellar systems are associated with infant motor and adult executive functions in healthy adults but not in schizophrenia
    Khanum Ridler
    Brain Mapping Unit, Department of Psychiatry, Addenbrooke s Hospital, University of Cambridge, Cambridge CB2 2QQ, United Kingdom
    Proc Natl Acad Sci U S A 103:15651-6. 2006
    ..Disruption of this anatomical system may underlie both the early developmental and adult cognitive abnormalities in schizophrenia...
  16. doi request reprint Default mode network in young people with familial risk for psychosis--the Oulu Brain and Mind study
    Tuomas Jukuri
    Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, Finland
    Schizophr Res 143:239-45. 2013
    ..We compared the activity of the DMN between FR participants and controls...
  17. ncbi request reprint Associations between early development and outcome in schizophrenia--A 35-year follow-up of the Northern Finland 1966 Birth Cohort
    Erika Jaaskelainen
    Department of Psychiatry, University of Oulu, Finland, P O Box 5000, 90014 University of Oulu, Finland
    Schizophr Res 99:29-37. 2008
    ..We conclude that risk factors for schizophrenia are not necessarily prognostic factors...
  18. doi request reprint Young people at risk for psychosis: case finding and sample characteristics of the Oulu Brain and Mind Study
    Juha Veijola
    Departments of Psychiatry Child Psychiatry, Institute of Clinical Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland
    Early Interv Psychiatry 7:146-54. 2013
    ..We report the study methods and explore the relationship between these definitions of high risk for psychosis and operational criteria for a prodromal psychosis syndrome based on interview...
  19. ncbi request reprint The brain structural disposition to social interaction
    Maël Lebreton
    Brain Mapping Unit, University of Cambridge, Cambridge, UK
    Eur J Neurosci 29:2247-52. 2009
    ..These findings provide evidence for a brain structural disposition to social interaction, and that sensitivity to social reward shares a common neural basis with systems for processing primary reward information...
  20. ncbi request reprint Effects of modafinil on emotional processing in first episode psychosis
    Linda Scoriels
    Department of Psychiatry, University of Cambridge, Robinson Way, Cambridge, UK
    Biol Psychiatry 69:457-64. 2011
    ..We aimed to establish whether modafinil might have a role in the adjuvant treatment of emotional impairments in the first episode of psychosis, when therapeutic endeavor is arguably most vital...
  21. ncbi request reprint Learning and cognitive flexibility: frontostriatal function and monoaminergic modulation
    Angie A Kehagia
    Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Curr Opin Neurobiol 20:199-204. 2010
    ..The role of prefrontal noradrenaline (NA) in higher order flexibility indexed through attentional set-shifting has recently received significant empirical support, and similar avenues appear promising in the field of task switching...
  22. doi request reprint Brain structure in different psychosis risk groups in the Northern Finland 1986 birth cohort
    Andres Roman-Urrestarazu
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Schizophr Res 153:143-9. 2014
    ..These findings are consistent with an evolving pattern of cerebellar deficits in psychosis risk with the most pronounced deficits in those at highest risk of psychosis. ..
  23. ncbi request reprint Predictors of schizophrenia: evidence from the Northern Finland 1966 Birth Cohort and other sources
    Matti Isohanni
    Department of Psychiatry, University of Oulu, PO Box 5000, Finland
    Br J Psychiatry Suppl 48:s4-7. 2005
    ..Subtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy individuals who later develop schizophrenia, suggesting that some aspects of causation are established before overt psychosis...
  24. ncbi request reprint Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, brain activity, and psychosis
    Philip R Corlett
    Brain Mapping Unit, Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, England
    Arch Gen Psychiatry 63:611-21. 2006
    ..Establishing a neurobiological account of delusion formation that links cognitive processes, brain activity, and symptoms is important to furthering our understanding of psychosis...
  25. ncbi request reprint Association of cannabis use with prodromal symptoms of psychosis in adolescence
    Jouko Miettunen
    Department of Psychiatry, University of Oulu, PO Box 5000, 90014 University of Oulu, Finland
    Br J Psychiatry 192:470-1. 2008
    ..23; 95% CI 1.70-2.94). A dose-response effect was seen. We conclude that cannabis use is associated with prodromal symptoms of psychosis in adolescence...
  26. ncbi request reprint The relevance of reward pathways for schizophrenia
    Hisham Ziauddeen
    Department of Psychiatry, University of Cambridge, UK
    Curr Opin Psychiatry 23:91-6. 2010
    ..We examine how disturbances in reward-related processes relate to the pathophysiology and symptomatology of this disorder...
  27. pmc Longitudinal changes in total brain volume in schizophrenia: relation to symptom severity, cognition and antipsychotic medication
    Juha Veijola
    Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, Oulu, Finland Department of Psychiatry, Oulu University Hospital, Oulu, Finland
    PLoS ONE 9:e101689. 2014
    ..In this population based sample, brain volume reduction continues in schizophrenia patients after the onset of illness, and antipsychotic medications may contribute to these reductions. ..
  28. ncbi request reprint Predictors of schizophrenia--a review
    Pirjo Maki
    Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014 University of Oulu, Finland
    Br Med Bull 73:1-15. 2005
    ....
  29. ncbi request reprint The persistence of developmental markers in childhood and adolescence and risk for schizophrenic psychoses in adult life. A 34-year follow-up of the Northern Finland 1966 birth cohort
    Matti Isohanni
    Department of Psychiatry, University of Oulu, P O Box 5000, 90014 Oulu, Finland
    Schizophr Res 71:213-25. 2004
    ..These findings are in line with the hypothesis that a neural diathesis is present during postnatal brain development before schizophrenia. This supports the longitudinal dimension and life span models of schizophrenia...
  30. pmc Effects of Methamphetamine Administration on Information Gathering during Probabilistic Reasoning in Healthy Humans
    Anna O Ermakova
    Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 9:e102683. 2014
    ..028). Our results suggest that information gathering during probabilistic reasoning is a stable trait, not easily modified by dopaminergic or noradrenergic modulation. ..
  31. ncbi request reprint Substance use in a population-based clinic sample of people with first-episode psychosis
    Jennifer H Barnett
    Department of Psychiatry, Box 189, University of Cambridge, UK
    Br J Psychiatry 190:515-20. 2007
    ..Substance use is implicated in the cause and course of psychosis...