Research Topics
Species | Andrew J MurraySummaryAffiliation: University of Aberdeen Country: UK Publications
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Detail Information
Publications
Pharmacological PKA inhibition: all may not be what it seemsAndrew J Murray
School of Medical Sciences, College of Life Sciences and Medicine, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
Sci Signal 1:re4. 2008..Here, I summarize the nonspecific effects of these two compounds and compare their actions with those of other PKA inhibitors...
Epac mediates cyclic AMP-dependent axon growth, guidance and regenerationAndrew J Murray
School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Institute of Medical Sciences, Forresterhill, Aberdeen AB25 2ZD, UK
Mol Cell Neurosci 38:578-88. 2008..We propose that Epac plays a role in mediating cAMP-dependent axon growth and guidance, and may provide an important target for inducing axon regeneration in vivo...
cGMP promotes neurite outgrowth and growth cone turning and improves axon regeneration on spinal cord tissue in combination with cAMPAndrew J Murray
School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, UK
Brain Res 1294:12-21. 2009....
cAMP-dependent axon guidance is distinctly regulated by Epac and protein kinase AAndrew J Murray
Institute of Medical Sciences, School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Forresterhill, Aberdeen AB25 2ZD, United Kingdom
J Neurosci 29:15434-44. 2009..Moreover, we propose that the developmental switch in growth cone response to gradients of cAMP-dependent guidance cues from attraction to repulsion is the result of a switch from Epac- to PKA-mediated signaling pathways...
