Research Topics
| A M MortimerSummaryAffiliation: University of Hull Country: UK Publications
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Detail Information
Publications
Clozapine for treatment-resistant schizophrenia: National Institute of Clinical Excellence (NICE) guidance in the real worldAnn M Mortimer
Department of Psychiatry, University of Hull, Hertford Building, Cottingham Road, Hull, East Yorkshire, HU6 7RX, U K
Clin Schizophr Relat Psychoses 4:49-55. 2010..Levels of ongoing clinical problems were compared between treatment-resistant patients on clozapine, treatment-resistant patients not on clozapine, and non-treatment-resistant patients...
Symptom rating scales and outcome in schizophreniaAnn M Mortimer
Department of Psychiatry, University of Hull
Br J Psychiatry Suppl 50:s7-14. 2007..Symptom rating scales are now well established in schizophrenia research but their scores are not the same as outcome...
Treatment with amisulpride and olanzapine improve neuropsychological function in schizophreniaAnn M Mortimer
University of Hull, Hull, UK
Hum Psychopharmacol 22:445-54. 2007..Although antipsychotic drugs control acute psychotic manifestations of schizophrenia, improving cognitive symptoms is also important for long-term prognosis...
Conventional antipsychotic prescription in unipolar depression, II: withdrawing conventional antipsychotics in unipolar, nonpsychotic patientsAnn M Mortimer
Department of Psychiatry, the University of Hull School of Medicine, Willerby, United Kingdom
J Clin Psychiatry 64:668-72; quiz 738-9. 2003..Concerns regarding these patients' polypharmacy, duration of treatment, and risk of long-term or undetected side effects led to their being contacted with a view to the discontinuation of conventional antipsychotic treatment...
Antipsychotic treatment in schizophrenia: atypical options and NICE guidanceAnn M Mortimer
The Department of Psychiatry, University of Hull, East Riding Campus Willerby, Hull HU10 6NS, UK
Eur Psychiatry 18:209-19. 2003..There is a welcome emphasis on drug treatment as part of an integrated package of care negotiated with patients and their carers...
Relationship between estrogen and schizophreniaA M Mortimer
The University of Hull, Department of Psychiatry, Hertford Building, Cottingham Road, Hull HU6 7RX, UK
Expert Rev Neurother 7:45-55. 2007....
How do we choose between atypical antipsychotics? The advantages of amisulprideAnn M Mortimer
Department of Psychiatry, The University of Hull, East Riding Campus, Beverley Road, Willerby, Hull HU10 6NS, UK
Int J Neuropsychopharmacol 7:S21-5. 2004..In two clinical trials, the AMIRIS and SOLIANOL studies, amisulpride demonstrated clear advantages over some other atypical antipsychotics with respect to negative symptoms, depressive symptoms and weight gain...
A double-blind, randomized comparative trial of amisulpride versus olanzapine for 6 months in the treatment of schizophreniaAnn Mortimer
University of Hull, Hull, UK
Int Clin Psychopharmacol 19:63-9. 2004..1% and 3.9 kg) than in the amisulpride group (20.6% and 1.6 kg). The efficacy of amisulpride is not inferior to that of olanzapine in the treatment of acute schizophrenia. The side-effect profile of the two drugs differed...
Somatic treatment of psychotic depression: review and recommendations for practiceJ A Wheeler Vega
Department of Psychiatry, University of Hull, England
J Clin Psychopharmacol 20:504-19. 2000..These recommendations aim to minimize the number of treatments used and unwanted effects experienced...
Are the cognitive effects of atypical antipsychotics influenced by their affinity to 5HT-2A receptors?Philip J Tyson
School of Health and Social Sciences, University of Gloucestershire, Francis Close Hall Campus, Cheltenham, Gloucestershire, United Kingdom
Int J Neurosci 114:593-611. 2004..In contrast, the low-5HT-2A affinity group showed improvements on these measures in addition to others. The 5HT-2A affinity of the atypical antipsychotics is an important determinant of their cognitive effects...
Stability of set-shifting and planning abilities in patients with schizophreniaPhilip J Tyson
School of Health and Social Sciences, University of Gloucestershire, Francis Close Hall Campus, Swindon Road, Cheltenham, Gloucestershire, GL50 4AZ, UK
Psychiatry Res 129:229-39. 2004..This study accords with the presence of executive processing deficits in schizophrenia that are stable across time...
Cognitive function and social abilities in patients with schizophrenia: relationship with atypical antipsychoticsPhilip J Tyson
School of Natural and Social Sciences, University of Gloucestershire, Cheltenham, UK
Psychiatry Clin Neurosci 60:473-9. 2006..These findings accord with the notion that serotonergic mechanisms are important determinants of both the cognitive and the social effects of the atypical antipsychotics...
Quality of life in schizophrenia on conventional versus atypical antipsychotic medication: a comparative cross-sectional studyAnn M Mortimer
Department of Psychiatry, University of Hull, UK
Int J Soc Psychiatry 53:99-107. 2007..Atypical antipsychotic drugs, with superior tolerability and possibly superior efficacy, were expected to give schizophrenia patients better quality of life (QOL) than conventional treatment. Research findings are equivocal...
Conventional antipsychotic prescription in unipolar depression, I: an audit and recommendations for practiceJason A Wheeler Vega
Department of Psychology, New School for Social Research, New York, NY, USA
J Clin Psychiatry 64:568-74. 2003..CONCLUSION: Current clinical guidelines commend careful antidepressant choice in preference to polypharmacy. A number of drug choices for specific depressive presentations are summarized from recent sources...
Early development and unstable genes in schizophrenia: preliminary resultsAgnes Ayton
Department of Psychiatry, University of Hull, East Riding Campus, Coniston House, Willerby, East Yorkshire HU10 6NS, UK
Eur Psychiatry 17:332-8. 2002..Trinucleotide repeats have been associated with schizophrenia, but the evidence, based on cross-sectional clinical information, is equivocal...
Intellectual differences between schizophrenic patients and normal controls across the adult lifespanTejinder K Kondel
Department of Clinical and Health Psychology, University College London, London, UK
J Clin Exp Neuropsychol 25:1045-56. 2003..We propose that the lower NART IQ in older patients reflects a lower 'starting point' and that this may be related to lower educational opportunities in older patients...
Novel antipsychotics in schizophreniaAnn M Mortimer
Department of Psychiatry, University of Hull, UK
Expert Opin Investig Drugs 13:315-29. 2004..Progress in drug treatment for schizophrenia is confronted by several areas of difficulty which, barring serendipity, must be resolved before real advances can be anticipated...
