Liam J Morrison
Affiliation: University of Glasgow
Morrison L, McCormack G, Sweeney L, Likeufack A, Truc P, Turner C, et al
. Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters. Am J Trop Med Hyg. 2007;76:1132-7 pubmed
..The use of MDA allows maximal use of finite DNA samples and may prove a valuable tool in studies where multiple reactions are necessary, such as population genetic analyses. ..
Morrison L, Mallon M, Smith H, MacLeod A, Xiao L, Tait A. The population structure of the Cryptosporidium parvum population in Scotland: a complex picture. Infect Genet Evol. 2008;8:121-9 pubmed
..Thus, the population structure of C. parvum is complex, with sub-populations differing in structure and being influenced by host movements, including the introduction of novel multilocus genotypes from geographically distinct regions. ..
Morrison L, Tait A, McLellan S, Sweeney L, Turner C, MacLeod A. A major genetic locus in Trypanosoma brucei is a determinant of host pathology. PLoS Negl Trop Dis. 2009;3:e557 pubmed publisher
..The identification of parasite loci is a first step towards identifying the genes that are responsible for these important traits and shows the power of genetic analysis as a tool for dissecting complex quantitative phenotypic traits. ..
Morrison L, Tait A, McCormack G, Sweeney L, Black A, Truc P, et al
. Trypanosoma brucei gambiense Type 1 populations from human patients are clonal and display geographical genetic differentiation. Infect Genet Evol. 2008;8:847-54 pubmed publisher
..The finding of distinct clades in different places suggests the possibility that samples from humans with clinical signs represent clonal expansions from an underlying population that requires identifying and characterising...
Morrison L, Tweedie A, Black A, Pinchbeck G, Christley R, Schoenefeld A, et al
. Discovery of mating in the major African livestock pathogen Trypanosoma congolense. PLoS ONE. 2009;4:e5564 pubmed publisher
Morrison L, McLellan S, Sweeney L, Chan C, MacLeod A, Tait A, et al
. Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection. Infect Immun. 2010;78:1096-108 pubmed publisher
..Furthermore, it is necessary to incorporate parasite variation into both experimental systems and models of pathogenesis. ..