T William J Moorhead

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi request reprint Voxel-based morphometry of comorbid schizophrenia and learning disability: analyses in normalized and native spaces using parametric and nonparametric statistical methods
    T William J Moorhead
    Image Analysis Laboratory, Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh EH10 5HF, Scotland, UK
    Neuroimage 22:188-202. 2004
  2. ncbi request reprint Empirical comparison of maximal voxel and non-isotropic adjusted cluster extent results in a voxel-based morphometry study of comorbid learning disability with schizophrenia
    T William J Moorhead
    Division of Psychiatry, Image Analysis Laboratory, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland UK
    Neuroimage 28:544-52. 2005
  3. ncbi request reprint Automated computation of the Gyrification Index in prefrontal lobes: methods and comparison with manual implementation
    T William J Moorhead
    Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland, UK
    Neuroimage 31:1560-6. 2006
  4. doi request reprint Changes in gyrification over 4 years in bipolar disorder and their association with the brain-derived neurotrophic factor valine(66) methionine variant
    Ajay Mirakhur
    Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh EH10 5HF, United Kingdom
    Biol Psychiatry 66:293-7. 2009
  5. doi request reprint Genetic variation in the DAOA (G72) gene modulates hippocampal function in subjects at high risk of schizophrenia
    Jeremy Hall
    Division of Psychiatry, University of Edinburgh, United Kingdom
    Biol Psychiatry 64:428-33. 2008
  6. ncbi request reprint Increased prefrontal gyrification in a large high-risk cohort characterizes those who develop schizophrenia and reflects abnormal prefrontal development
    Jonathan M Harris
    Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
    Biol Psychiatry 62:722-9. 2007
  7. doi request reprint Structural abnormalities of ventrolateral and orbitofrontal cortex in patients with familial bipolar disorder
    Andrew C Stanfield
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK
    Bipolar Disord 11:135-44. 2009
  8. doi request reprint White matter abnormalities in bipolar disorder and schizophrenia detected using diffusion tensor magnetic resonance imaging
    Jessika E Sussmann
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK
    Bipolar Disord 11:11-8. 2009
  9. ncbi request reprint Increased right prefrontal cortical folding in adolescents at risk of schizophrenia for cognitive reasons
    Andrew C Stanfield
    Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom
    Biol Psychiatry 63:80-5. 2008
  10. ncbi request reprint White matter density in patients with schizophrenia, bipolar disorder and their unaffected relatives
    Andrew M McIntosh
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, Scotland, UK
    Biol Psychiatry 58:254-7. 2005

Detail Information

Publications21

  1. ncbi request reprint Voxel-based morphometry of comorbid schizophrenia and learning disability: analyses in normalized and native spaces using parametric and nonparametric statistical methods
    T William J Moorhead
    Image Analysis Laboratory, Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh EH10 5HF, Scotland, UK
    Neuroimage 22:188-202. 2004
    ..VBM has the facility to compare grey matter distributions in this structurally diverse cohort...
  2. ncbi request reprint Empirical comparison of maximal voxel and non-isotropic adjusted cluster extent results in a voxel-based morphometry study of comorbid learning disability with schizophrenia
    T William J Moorhead
    Division of Psychiatry, Image Analysis Laboratory, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland UK
    Neuroimage 28:544-52. 2005
    ....
  3. ncbi request reprint Automated computation of the Gyrification Index in prefrontal lobes: methods and comparison with manual implementation
    T William J Moorhead
    Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, Scotland, UK
    Neuroimage 31:1560-6. 2006
    ..A-GI is therefore a reliable measure of cortical folding that could be usefully applied to a number of MRI data sets of the brain in health and disease...
  4. doi request reprint Changes in gyrification over 4 years in bipolar disorder and their association with the brain-derived neurotrophic factor valine(66) methionine variant
    Ajay Mirakhur
    Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh EH10 5HF, United Kingdom
    Biol Psychiatry 66:293-7. 2009
    ..The present study examined longitudinal trends in prefrontal gyrification index (GI) in bipolar disorder and the effect of BDNF genotype...
  5. doi request reprint Genetic variation in the DAOA (G72) gene modulates hippocampal function in subjects at high risk of schizophrenia
    Jeremy Hall
    Division of Psychiatry, University of Edinburgh, United Kingdom
    Biol Psychiatry 64:428-33. 2008
    ..Preliminary evidence in healthy control subjects has implicated genetic variation in the DAOA gene in the modulation of hippocampal complex and prefrontal cortex activation...
  6. ncbi request reprint Increased prefrontal gyrification in a large high-risk cohort characterizes those who develop schizophrenia and reflects abnormal prefrontal development
    Jonathan M Harris
    Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
    Biol Psychiatry 62:722-9. 2007
    ....
  7. doi request reprint Structural abnormalities of ventrolateral and orbitofrontal cortex in patients with familial bipolar disorder
    Andrew C Stanfield
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK
    Bipolar Disord 11:135-44. 2009
    ..We examined the presence and location of ventral prefrontal abnormalities in a large sample of individuals with bipolar disorder and their relationship to gender, psychotic symptoms, and age...
  8. doi request reprint White matter abnormalities in bipolar disorder and schizophrenia detected using diffusion tensor magnetic resonance imaging
    Jessika E Sussmann
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK
    Bipolar Disord 11:11-8. 2009
    ..Diffusion tensor imaging (DTI) studies suggest altered connectivity in both disorders. We aim to address the diagnostic specificity of white matter abnormalities in these disorders...
  9. ncbi request reprint Increased right prefrontal cortical folding in adolescents at risk of schizophrenia for cognitive reasons
    Andrew C Stanfield
    Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom
    Biol Psychiatry 63:80-5. 2008
    ..We examined the association between these measures in adolescents at enhanced risk of developing schizophrenia due to cognitive impairment...
  10. ncbi request reprint White matter density in patients with schizophrenia, bipolar disorder and their unaffected relatives
    Andrew M McIntosh
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, Scotland, UK
    Biol Psychiatry 58:254-7. 2005
    ..This study sought to assess white matter density in patients and relatives with histories of bipolar disorder and/or schizophrenia...
  11. ncbi request reprint Relationship of catechol-O-methyltransferase variants to brain structure and function in a population at high risk of psychosis
    Andrew M McIntosh
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom
    Biol Psychiatry 61:1127-34. 2007
    ....
  12. doi request reprint Functional Magnetic Resonance Imaging (fMRI) reproducibility and variance components across visits and scanning sites with a finger tapping task
    Viktoria Eleni Gountouna
    Division of Psychiatry, The University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK
    Neuroimage 49:552-60. 2010
    ....
  13. ncbi request reprint Grey matter correlates of early psychotic symptoms in adolescents at enhanced risk of psychosis: a voxel-based study
    Michael D Spencer
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, EH10 5HF, UK
    Neuroimage 35:1181-91. 2007
    ....
  14. ncbi request reprint Structural correlates of intellectual impairment and autistic features in adolescents
    Michael D Spencer
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, EH10 5HF, UK
    Neuroimage 33:1136-44. 2006
    ....
  15. pmc Low birthweight and preterm birth in young people with special educational needs: a magnetic resonance imaging analysis
    Michael D Spencer
    Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK
    BMC Med 6:1. 2008
    ..Our aim was to address these issues in a sample of young people receiving additional learning support...
  16. ncbi request reprint Progressive gray matter loss in patients with bipolar disorder
    T William J Moorhead
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom
    Biol Psychiatry 62:894-900. 2007
    ..We sought to address these uncertainties in a prospective cohort study of people with bipolar I disorder...
  17. doi request reprint White matter integrity in individuals at high genetic risk of bipolar disorder
    Emma Sprooten
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, United Kingdom
    Biol Psychiatry 70:350-6. 2011
    ....
  18. pmc Prospective multi-centre Voxel Based Morphometry study employing scanner specific segmentations: procedure development using CaliBrain structural MRI data
    T William J Moorhead
    The Division of Psychiatry, Centre for Clinical Brain Sciences, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, UK
    BMC Med Imaging 9:8. 2009
    ..The CaliBrain project was designed to provide for an assessment of scanner differences at three centres in Scotland, and to assess the practicality of pooling scans from multiple-centres...
  19. ncbi request reprint Qualitative assessment of brain anomalies in adolescents with mental retardation
    Michael D Spencer
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom
    AJNR Am J Neuroradiol 26:2691-7. 2005
    ..The neural basis of mental retardation is poorly understood. This study aimed to characterize structural anomalies of the brain in mental retardation and the relationship between them and the degree of mental retardation...
  20. ncbi request reprint Voxel-based morphometry of patients with schizophrenia or bipolar disorder and their unaffected relatives
    Andrew M McIntosh
    Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom
    Biol Psychiatry 56:544-52. 2004
    ..This study sought to examine these issues and clarify the associations of phenotypic expression and genetic liability...
  21. doi request reprint Longitudinal gray matter change in young people who are at enhanced risk of schizophrenia due to intellectual impairment
    T William J Moorhead
    Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
    Biol Psychiatry 73:985-92. 2013
    ..We aimed to determine whether findings from these studies are also applicable to those at enhanced risk of developing schizophrenia for another reason-intellectual impairment...