R Andrew Moore

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi Challenges in design and interpretation of chronic pain trials
    R A Moore
    Pain Research and Nuffield Division of Anaesthetics, Nuffield Department of Clinical Neurosciences, University of Oxford, The Churchill, Oxford OX3 7LE, UK
    Br J Anaesth 111:38-45. 2013
  2. doi Amitriptyline for neuropathic pain and fibromyalgia in adults
    R Andrew Moore
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 12:CD008242. 2012
  3. pmc Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, UK
    BMC Musculoskelet Disord 8:73. 2007
  4. doi Fibromyalgia: Moderate and substantial pain intensity reduction predicts improvement in other outcomes and substantial quality of life gain
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Pain 149:360-4. 2010
  5. ncbi Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults
    Sheena Derry
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 11:CD008040. 2010
  6. pmc Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford OX3 7LJ, UK
    Arthritis Res Ther 10:R39. 2008
  7. ncbi Outcomes in acute pain trials: systematic review of what was reported?
    Jodie Barden
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 109:351-6. 2004
  8. doi Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen, and ibuprofen/paracetamol combinations after third molar extraction
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, UK
    Pain 152:982-9. 2011
  9. pmc Systematic review of dexketoprofen in acute and chronic pain
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK
    BMC Clin Pharmacol 8:11. 2008
  10. doi Diclofenac with or without an antiemetic for acute migraine headaches in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD008783. 2012

Collaborators

Detail Information

Publications67

  1. doi Challenges in design and interpretation of chronic pain trials
    R A Moore
    Pain Research and Nuffield Division of Anaesthetics, Nuffield Department of Clinical Neurosciences, University of Oxford, The Churchill, Oxford OX3 7LE, UK
    Br J Anaesth 111:38-45. 2013
    ..Newer designs, like enriched enrolment randomized withdrawal (EERW) trials or clinical effectiveness trials, are potentially more interesting and informative. ..
  2. doi Amitriptyline for neuropathic pain and fibromyalgia in adults
    R Andrew Moore
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 12:CD008242. 2012
    ..These types of pain can be treated with antidepressant drugs in doses below those at which the drugs act as antidepressants...
  3. pmc Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, UK
    BMC Musculoskelet Disord 8:73. 2007
    ..We calculated the absolute risk for each effect...
  4. doi Fibromyalgia: Moderate and substantial pain intensity reduction predicts improvement in other outcomes and substantial quality of life gain
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Pain 149:360-4. 2010
    ..Pain intensity reduction is a simple and effective predictor of which patients should continue treatment, and which should discontinue and try an alternative therapy...
  5. ncbi Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults
    Sheena Derry
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 11:CD008040. 2010
    ..Many sufferers choose not to, or are unable to, seek professional help and rely on over-the-counter analgesics. Co-therapy with an antiemetic should help to reduce nausea and vomiting commonly associated with migraine...
  6. pmc Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford OX3 7LJ, UK
    Arthritis Res Ther 10:R39. 2008
    ..We investigated whether dichotomous responder analysis provides a more informative interpretation of drug efficacy...
  7. ncbi Outcomes in acute pain trials: systematic review of what was reported?
    Jodie Barden
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 109:351-6. 2004
    ..Most useful would be all three. Further exploration would only be possible from analysis at the individual patient level...
  8. doi Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen, and ibuprofen/paracetamol combinations after third molar extraction
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, UK
    Pain 152:982-9. 2011
    ..5 and 1.6, respectively) produced the lowest (best) NNTs in the dental pain model. Timing of patient request for additional analgesia is an alternative analgesic efficacy outcome measure...
  9. pmc Systematic review of dexketoprofen in acute and chronic pain
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK
    BMC Clin Pharmacol 8:11. 2008
    ..We used published and unpublished information from randomised clinical trials (RCTs) of dexketoprofen in painful conditions to assess evidence on efficacy and harm...
  10. doi Diclofenac with or without an antiemetic for acute migraine headaches in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD008783. 2012
    ..Co-therapy with an antiemetic should help to reduce the nausea and vomiting commonly associated with migraine...
  11. pmc Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Oxford OX3 7LJ, UK
    Arthritis Res Ther 10:R53. 2008
    ..By contrast, company clinical trial reports include much more detail...
  12. pmc What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe NHS Trust, The Churchill, Headington, Oxford OX3 7LJ, UK
    Arthritis Res Ther 10:R20. 2008
    ....
  13. ncbi Bias from industry trial funding? A framework, a suggested approach, and a negative result
    Jodie Barden
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 121:207-18. 2006
    ..We propose a method based on potential conflict of interest within industry-sponsored trials. Using this method, established clinical trial results in acute pain and migraine appear to be unbiased...
  14. pmc Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe NHS Trust, Oxford, UK
    Arthritis Res Ther 7:R644-65. 2005
    ..Adverse event information is clearly presented in company clinical trial reports, which are an ideal source of information for systematic review and meta-analysis...
  15. doi Topical capsaicin (high concentration) for chronic neuropathic pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford
    Cochrane Database Syst Rev 2:CD007393. 2013
    ..The benefits are expected to last for about 12 weeks, when another application might be made...
  16. pmc Dose-response in direct comparisons of different doses of aspirin, ibuprofen and paracetamol (acetaminophen) in analgesic studies
    Henry J McQuay
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, UK
    Br J Clin Pharmacol 63:271-8. 2007
    ..Establishing the dose-response relationship for clinically useful doses of aspirin, ibuprofen and paracetamol has been difficult. Indirect comparison from meta-analysis is compromised by too little information at some doses...
  17. pmc Topical NSAIDs for acute pain: a meta-analysis
    Lorna Mason
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Fam Pract 5:10. 2004
    ..More trials, a better understanding of trial quality and bias, and a reclassification of certain drugs necessitate a new review...
  18. ncbi Single dose oral diflunisal for acute postoperative pain in adults
    Jack O Wasey
    Magdalen College, University of Oxford, High Street, Oxford, Oxfordshire, UK, OX1 4AU
    Cochrane Database Syst Rev 4:CD007440. 2010
    ..This property may be useful when regular dosing is needed, or when taking several doses of a shorter acting analgesic is impractical...
  19. ncbi Aspirin with or without an antiemetic for acute migraine headaches in adults
    Varo Kirthi
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 4:CD008041. 2010
    ..Addition of metoclopramide 10 mg improves relief of nausea and vomiting. Adverse events were mainly mild and transient, and were slightly more common with aspirin than placebo, but less common than with sumatriptan 100 mg...
  20. ncbi Single dose oral codeine, as a single agent, for acute postoperative pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 4:CD008099. 2010
    ..Higher doses were not evaluated...
  21. pmc Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis
    Lorna Mason
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Musculoskelet Disord 5:28. 2004
    ..More trials, a better understanding of trial quality and bias, and a reclassification of certain drugs necessitate a new review...
  22. doi Milnacipran for neuropathic pain and fibromyalgia in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 3:CD008244. 2012
    ..Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is sometimes used to treat chronic neuropathic pain and fibromyalgia...
  23. doi Caffeine as an analgesic adjuvant for acute pain in adults
    Christopher J Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 3:CD009281. 2012
    ..Caffeine has been added to common analgesics such as paracetamol, ibuprofen, and aspirin, in the belief that it enhances analgesic efficacy. Evidence to support this belief is limited and often based on invalid comparisons...
  24. doi Clonazepam for neuropathic pain and fibromyalgia in adults
    Ruth Corrigan
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 5:CD009486. 2012
    ..Clonazepam, a benzodiazepine, is an established antiepileptic drug, but its place in the treatment of neuropathic pain is unclear...
  25. pmc Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford, UK
    Arthritis Res Ther 7:R1046-51. 2005
    ..Because most trials were short, less than four weeks, and because few titrated the dose, these results have limited applicability to longer-term use of opioids in clinical practice. Suggestions for improved studies are made...
  26. doi Enriched enrolment with randomised withdrawal (EERW): Time for a new look at clinical trial design in chronic pain
    Henry J McQuay
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Pain 135:217-20. 2008
  27. pmc Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: systematic review of randomized trials using autologous chromium-labelled erythrocytes
    R Andrew Moore
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospitals, The Churchill, Headington, Oxford, OX3 7LJ, UK
    Arthritis Res Ther 10:R7. 2008
    ....
  28. ncbi Single dose oral analgesics for acute postoperative pain in adults
    R Andrew Moore
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LJ
    Cochrane Database Syst Rev 9:CD008659. 2011
    ..This overview brings together the results of all those reviews and assesses the reliability of available data...
  29. doi Sumatriptan (intranasal route of administration) for acute migraine attacks in adults
    Christopher J Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD009663. 2012
    ..Intranasal administration may be preferable to oral for individuals experiencing nausea and/or vomiting, although it is primarily absorbed in the gut, not the nasal mucosa...
  30. doi Lacosamide for neuropathic pain and fibromyalgia in adults
    Leslie Hearn
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD009318. 2012
    ....
  31. doi Phenytoin for neuropathic pain and fibromyalgia in adults
    Fraser Birse
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 5:CD009485. 2012
    ..Phenytoin is an established antiepileptic drug that has been used occasionally to treat intractable trigeminal neuralgia...
  32. doi Topical capsaicin (low concentration) for chronic neuropathic pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 9:CD010111. 2012
    ....
  33. pmc Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Musculoskelet Disord 7:79. 2006
    ....
  34. doi Topical agents in the treatment of rheumatic pain
    R Andrew Moore
    Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, The Churchill, Headington, Oxford OX3 9DU, UK
    Rheum Dis Clin North Am 34:415-32. 2008
    ..The best information is for topical diclofenac. For topical capsaicin, evidence of efficacy is trivial. For topical rubefacients there is no evidence of efficacy...
  35. ncbi Efficacy and safety of valdecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials
    Jayne E Edwards
    Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 111:286-96. 2004
    ..There were fewer gastrointestinal adverse event withdrawals and endoscopically detected ulcers. Convincing evidence of reduced major gastrointestinal adverse events could not be addressed by the trials...
  36. doi Single dose oral celecoxib for acute postoperative pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 3:CD004233. 2012
    ..Celecoxib is believed to be associated with fewer upper gastrointestinal adverse effects than conventional non-steroidal anti-inflammatory drugs (NSAIDs). Its effectiveness in acute pain was demonstrated in the earlier reviews...
  37. pmc Enriched enrollment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review
    Sebastian Straube
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford, UK
    Br J Clin Pharmacol 66:266-75. 2008
    ..We aim to investigate whether this really is the case in trials of pregabalin and gabapentin in neuropathic pain...
  38. doi Can observational studies provide a realistic alternative to randomized controlled trials in palliative care?
    Gina Hadley
    Pain Research Unit, Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK
    J Pain Palliat Care Pharmacother 23:106-13. 2009
    ..We found that palliative care is deficient not only in RCTs, but also good quality observational studies. Those that exist are extremely heterogeneous in subject, design, outcome reporting, and intervention...
  39. doi Sumatriptan (subcutaneous route of administration) for acute migraine attacks in adults
    Christopher J Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD009665. 2012
    ..Sumatriptan is an abortive medication for migraine attacks, belonging to the triptan family. Subcutaneous administration may be preferable to oral for individuals experiencing nausea and/or vomiting..
  40. doi Sumatriptan (oral route of administration) for acute migraine attacks in adults
    Christopher J Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD008615. 2012
    ..Sumatriptan is an abortive medication for migraine attacks, belonging to the triptan family...
  41. doi Sumatriptan (rectal route of administration) for acute migraine attacks in adults
    Christopher J Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 2:CD009664. 2012
    ..Sumatriptan is an abortive medication for migraine attacks, belonging to the triptan family. Rectal administration may be preferable to oral for individuals experiencing nausea and/or vomiting...
  42. doi Single dose oral etoricoxib for acute postoperative pain in adults
    Rachel Clarke
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 4:CD004309. 2012
    ..One additional study in acute postoperative pain has been published since the original review was completed in Issue 2, 2009...
  43. pmc Indirect comparison of interventions using published randomised trials: systematic review of PDE-5 inhibitors for erectile dysfunction
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe NHS Trust, The Churchill, Headington, Oxford, OX37LJ, UK
    BMC Urol 5:18. 2005
    ..Valid indirect comparisons with a common comparator must examine equivalent doses, similar duration, similar populations, with the same outcomes reported in the same way...
  44. doi Intracutaneous or subcutaneous sterile water injection compared with blinded controls for pain management in labour
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 1:CD009107. 2012
    ..Adequate analgesia in labour is important to women worldwide. Sterile water injection is inexpensive, requires basic equipment, and appears to have few side effects. It is purported to work for labour pain...
  45. pmc Duloxetine for painful diabetic neuropathy and fibromyalgia pain: systematic review of randomised trials
    Asquad Sultan
    Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    BMC Neurol 8:29. 2008
    ..We investigated the efficacy of duloxetine in painful diabetic neuropathy and fibromyalgia to allow comparison with other antidepressants...
  46. ncbi Triptans for acute cluster headache
    Simon Law
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 4:CD008042. 2010
    ..Non-oral routes of administration are likely to provide better and more rapid responses...
  47. ncbi Pharmacological treatments for acute migraine: quantitative systematic review
    Anna D Oldman
    Pain Research, Nuffield Department of Anaesthetics, Oxford Radcliffe Hospital, University of Oxford, The Churchill, Headington, UK
    Pain 97:247-57. 2002
    ..8 for eletriptan 80mg to 8.3 for rizatriptan 5mg. It was not possible to systematically review adverse effects data. Most interventions are effective. There is considerable information on relative efficacy for a number of outcomes...
  48. doi Single dose oral ibuprofen plus codeine for acute postoperative pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 3:CD010107. 2013
    ..Some combinations of ibuprofen and codeine are available without prescription (but usually only from a pharmacy) where the dose of codeine is lower, and with a prescription when the dose of codeine is higher...
  49. doi Topical NSAIDs for chronic musculoskeletal pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 9:CD007400. 2012
    ..One of the problems has been that older clinical studies were generally short, lasting four weeks or less, and short duration studies are not regarded as adequate in ongoing painful conditions...
  50. doi Single dose oral aspirin for acute postoperative pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LE
    Cochrane Database Syst Rev 4:CD002067. 2012
    ..Although its use as an analgesic is now limited in developed countries, it is widely available, inexpensive, and remains commonly used throughout the world...
  51. ncbi Gabapentin for chronic neuropathic pain and fibromyalgia in adults
    R Andrew Moore
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LJ
    Cochrane Database Syst Rev 3:CD007938. 2011
    ..Antiepileptic drugs are used to manage pain, predominantly for chronic neuropathic pain, especially when the pain is lancinating or burning...
  52. ncbi Carbamazepine for acute and chronic pain in adults
    Philip J Wiffen
    UK Cochrane Centre, National Institute for Health Research, Summertown Pavilion, Middle Way, Oxford, UK, OX2 7LG
    Cochrane Database Syst Rev 1:CD005451. 2011
    ..Carbamazepine is used to treat chronic neuropathic pain...
  53. pmc Finasteride in the treatment of clinical benign prostatic hyperplasia: a systematic review of randomised trials
    Jayne E Edwards
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospitals, The Churchill, Headington, Oxford, UK
    BMC Urol 2:14. 2002
    ..Benign prostatic hyperplasia affects older men. This systematic review determined efficacy and adverse effects of finasteride...
  54. pmc Atypical antipsychotics in bipolar disorder: systematic review of randomised trials
    Sheena Derry
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospitals, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Psychiatry 7:40. 2007
    ..Atypical antipsychotics are increasingly used for treatment of mental illnesses like schizophrenia and bipolar disorder, and considered to have fewer extrapyramidal effects than older antipsychotics...
  55. pmc Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials
    Jayne E Edwards
    Pain Research Unit and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Fam Pract 4:18. 2003
    ..Statins alter lipid concentrations. This systematic review determined the efficacy of particular statins, in terms of their ability to alter cholesterol...
  56. doi Single dose oral ibuprofen plus oxycodone for acute postoperative pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 6:CD010289. 2013
    ..Fixed-dose combinations of ibuprofen and oxycodone are available, and the drugs may be separately used in combination in some acute pain situations...
  57. doi Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain
    Christopher J Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 6:CD010210. 2013
    ..Some combinations of ibuprofen and paracetamol are available for use without prescription in some acute pain situations...
  58. doi Oral morphine for cancer pain
    Philip J Wiffen
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 7:CD003868. 2013
    ..Morphine has been used for many years to relieve pain. Oral morphine in either immediate release or modified release form remains the analgesic of choice for moderate or severe cancer pain...
  59. doi Diclofenac with or without an antiemetic for acute migraine headaches in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 4:CD008783. 2013
    ..Co-therapy with an antiemetic should help to reduce the nausea and vomiting commonly associated with migraine...
  60. doi Aspirin with or without an antiemetic for acute migraine headaches in adults
    Varo Kirthi
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 4:CD008041. 2013
    ..Many sufferers choose not to, or are unable to, seek professional help and rely on over-the-counter analgesics. Co-therapy with an antiemetic should help to reduce nausea and vomiting commonly associated with migraine headaches...
  61. ncbi WITHDRAWN: Gabapentin for acute and chronic pain
    Philip J Wiffen
    UK Cochrane Centre, National Institute for Health Research, Summertown Pavilion, Middle Way, Oxford, UK, OX2 7LG
    Cochrane Database Syst Rev 3:CD005452. 2011
    ..Anticonvulsant drugs have been used in the management of pain since the 1960s. The clinical impression is that they are useful for chronic neuropathic pain, especially when the pain is lancinating or burning...
  62. ncbi Single dose oral mefenamic acid for acute postoperative pain in adults
    Rachel Moll
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LJ
    Cochrane Database Syst Rev 3:CD007553. 2011
    ..It is widely available in many countries worldwide...
  63. ncbi Valproic acid and sodium valproate for neuropathic pain and fibromyalgia in adults
    Dipender Gill
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LJ
    Cochrane Database Syst Rev 10:CD009183. 2011
    ..Valproic acid and its sodium salt (sodium valproate) are antiepileptic drugs that are sometimes used to treat chronic neuropathic pain and fibromyalgia, although they are not licensed for this use...
  64. ncbi Lamotrigine for acute and chronic pain
    Philip J Wiffen
    UK Cochrane Centre, National Institute for Health Research, Summertown Pavilion, Middle Way, Oxford, UK, OX2 7LG
    Cochrane Database Syst Rev 2:CD006044. 2011
    ..This updated review adds five new additional studies looking at evidence for Lamotrigine as an effective treatment for acute and chronic pain...
  65. doi Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults
    Sheena Derry
    Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cochrane Database Syst Rev 4:CD008040. 2013
    ..Many sufferers choose not to, or are unable to, seek professional help and rely on over-the-counter analgesics. Co-therapy with an antiemetic should help to reduce nausea and vomiting, which are commonly associated with migraine...
  66. pmc Meta-analysis of efficacy and safety of intravenous ferric carboxymaltose (Ferinject) from clinical trial reports and published trial data
    R Andrew Moore
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospitals, The Churchill, Oxford, OX3 7LJ, UK
    BMC Blood Disord 11:4. 2011
    ..abstract:..
  67. ncbi Single dose oral fenoprofen for acute postoperative pain in adults
    Maria X Traa
    Pain Research and Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LJ
    Cochrane Database Syst Rev 2:CD007556. 2011
    ..Fenoprofen is a non-steroidal anti-inflammatory drug (NSAID), available in several different countries, but not widely used...