Anne C Moore

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Progress in DNA-based heterologous prime-boost immunization strategies for malaria
    Anne C Moore
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Immunol Rev 199:126-43. 2004
  2. ncbi request reprint Anti-CD25 antibody enhancement of vaccine-induced immunogenicity: increased durable cellular immunity with reduced immunodominance
    Anne C Moore
    Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, United Kingdom
    J Immunol 175:7264-73. 2005
  3. doi request reprint Single-dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei
    Arturo Reyes-Sandoval
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Eur J Immunol 38:732-41. 2008
  4. doi request reprint Effective induction of high-titer antibodies by viral vector vaccines
    Simon J Draper
    The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK
    Nat Med 14:819-21. 2008
  5. pmc Combination of protein and viral vaccines induces potent cellular and humoral immune responses and enhanced protection from murine malaria challenge
    Claire L Hutchings
    Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
    Infect Immun 75:5819-26. 2007
  6. pmc Recombinant viral vaccines expressing merozoite surface protein-1 induce antibody- and T cell-mediated multistage protection against malaria
    Simon J Draper
    The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK
    Cell Host Microbe 5:95-105. 2009
  7. ncbi request reprint Novel protein and poxvirus-based vaccine combinations for simultaneous induction of humoral and cell-mediated immunity
    Claire L Hutchings
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    J Immunol 175:599-606. 2005
  8. pmc The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment
    Anna L Goodman
    The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
    Sci Rep 3:1706. 2013
  9. pmc A Plasmodium falciparum candidate vaccine based on a six-antigen polyprotein encoded by recombinant poxviruses
    Eric Prieur
    Weatherall Institute of Molecular Medicine and Cellular Immunology, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 101:290-5. 2004
  10. pmc Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1
    Teresa Lambe
    The Jenner Institute, University of Oxford, Oxford, United Kingdom
    Sci Rep 3:1443. 2013

Detail Information

Publications14

  1. ncbi request reprint Progress in DNA-based heterologous prime-boost immunization strategies for malaria
    Anne C Moore
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Immunol Rev 199:126-43. 2004
    ..We summarize the preclinical design and development of these heterologous prime-boost vaccines and discuss the encouraging results that have been observed in vaccinated humans...
  2. ncbi request reprint Anti-CD25 antibody enhancement of vaccine-induced immunogenicity: increased durable cellular immunity with reduced immunodominance
    Anne C Moore
    Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, United Kingdom
    J Immunol 175:7264-73. 2005
    ..Vaccine strategies incorporating anti-CD25 lead to improved protection against pre-erythrocytic malaria challenge. These data underpin new strategies for the design and development of more efficacious vaccines in clinical settings...
  3. doi request reprint Single-dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei
    Arturo Reyes-Sandoval
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Eur J Immunol 38:732-41. 2008
    ..Our data suggest that T(EM) cells are important as a first line of defense against fast-replicating pathogens such as murine Plasmodium and demonstrate the potential of replication-defective SAd as future malaria vaccines for humans...
  4. doi request reprint Effective induction of high-titer antibodies by viral vector vaccines
    Simon J Draper
    The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK
    Nat Med 14:819-21. 2008
    ..Antibodies induced against a blood-stage malaria antigen by this viral vector platform are highly effective against Plasmodium yoelii parasites in mice and against Plasmodium falciparum in vitro...
  5. pmc Combination of protein and viral vaccines induces potent cellular and humoral immune responses and enhanced protection from murine malaria challenge
    Claire L Hutchings
    Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
    Infect Immun 75:5819-26. 2007
    ....
  6. pmc Recombinant viral vaccines expressing merozoite surface protein-1 induce antibody- and T cell-mediated multistage protection against malaria
    Simon J Draper
    The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK
    Cell Host Microbe 5:95-105. 2009
    ..Multistage immunity against malaria can thus be achieved by using viral vectors recombinant for MSP-1...
  7. ncbi request reprint Novel protein and poxvirus-based vaccine combinations for simultaneous induction of humoral and cell-mediated immunity
    Claire L Hutchings
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    J Immunol 175:599-606. 2005
    ....
  8. pmc The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment
    Anna L Goodman
    The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
    Sci Rep 3:1706. 2013
    ..An improved understanding of the mechanisms responsible for protection, or failure of protection, against P. berghei merozoites could guide the development of an efficacious vaccine against P. falciparum...
  9. pmc A Plasmodium falciparum candidate vaccine based on a six-antigen polyprotein encoded by recombinant poxviruses
    Eric Prieur
    Weatherall Institute of Molecular Medicine and Cellular Immunology, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 101:290-5. 2004
    ..The use of polyprotein constructs in nonreplicating poxviruses should broaden the target antigen range of vaccine-induced immunity and increase the number of potential epitopes available for immunogenetically diverse human populations...
  10. pmc Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1
    Teresa Lambe
    The Jenner Institute, University of Oxford, Oxford, United Kingdom
    Sci Rep 3:1443. 2013
    ..These data may be of relevance for the design of optimal immunization regimens for human influenza vaccines, especially for influenza-naïve infants...
  11. ncbi request reprint Combination vaccines: synergistic simultaneous induction of antibody and T-cell immunity
    Anne C Moore
    Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Oxford OX2 7BN, UK
    Expert Rev Vaccines 6:111-21. 2007
    ..Combination vaccines, where an antibody-inducing subunit protein vaccine is coadministered with a T-cell-inducing poxvirus-based vaccine fulfill these requirements and induce sterile immunity to pathogen challenge...
  12. pmc Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria
    Nathan W Schmidt
    Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA
    Proc Natl Acad Sci U S A 105:14017-22. 2008
    ..Furthermore, the extremely large threshold in memory CD8 T cell frequencies required for long-term protection in mice may have important implications for development of effective malaria vaccines...
  13. pmc Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice
    Anne C Moore
    Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 3005, USA
    J Virol 76:243-50. 2002
    ....
  14. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-2002. A 37-year-old man with fever, hepatosplenomegaly, and a cutaneous foot lesion after a trip to Africa
    Anne C Moore
    N Engl J Med 346:2069-76. 2002