Rohit Mittal

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling
    Rohit Mittal
    Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
    Proc Natl Acad Sci U S A 103:18574-9. 2006
  2. pmc The acetyltransferase activity of the bacterial toxin YopJ of Yersinia is activated by eukaryotic host cell inositol hexakisphosphate
    Rohit Mittal
    Medical Research Council MRC, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    J Biol Chem 285:19927-34. 2010
  3. pmc FCHo proteins are nucleators of clathrin-mediated endocytosis
    William Mike Henne
    Medical Research Council, Laboratory of Molecular Biology MRC LMB, Hills Road, Cambridge CB2 0QH, UK
    Science 328:1281-4. 2010
  4. pmc Cooperative recruitment of dynamin and BIN/amphiphysin/Rvs (BAR) domain-containing proteins leads to GTP-dependent membrane scission
    Michael Meinecke
    Laboratory of Molecular Biology, Medical Research Council, Hills Road, Cambridge CB2 0QH, United Kingdom
    J Biol Chem 288:6651-61. 2013
  5. ncbi request reprint Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature
    William Mike Henne
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB1 0QH, United Kingdom
    Structure 15:839-52. 2007
  6. ncbi request reprint Effects of remote mutation on the autolysis of HIV-1 PR: X-ray and NMR investigations
    Mukesh Kumar
    Solid State Physics Division, Bhabha Atomic Research Centre, Mumbai 400 005, India
    Biochem Biophys Res Commun 294:395-401. 2002
  7. ncbi request reprint Structural characterization of the large soluble oligomers of the GTPase effector domain of dynamin
    Jeetender Chugh
    Department of Chemical Sciences, Tata Institute of Fundamental Reseach, Mumbai, India
    FEBS J 273:388-97. 2006
  8. pmc Local structural preferences and dynamics restrictions in the urea-denatured state of SUMO-1: NMR characterization
    Ashutosh Kumar
    Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai, India
    Biophys J 90:2498-509. 2006

Collaborators

  • Harvey T McMahon
  • William Mike Henne
  • Michael Meinecke
  • Ashutosh Kumar
  • Emmanuel Boucrot
  • Ram Kumar Mishra
  • Ramakrishna V Hosur
  • Jeetender Chugh
  • Amarnath Chatterjee
  • Mukesh Kumar
  • Wai Ching Hon
  • Gamze Camdere
  • Emma Evergren
  • Yvonne Vallis
  • Oliver Daumke
  • Ralf Langen
  • Philip R Evans
  • Balachandra G Hegde
  • Helen M Kent
  • Marijn G J Ford
  • P Jonathan G Butler
  • Sudha Srivastava
  • R V Hosur
  • Neel S Bhavesh
  • M V Hosur
  • K K Kannan

Detail Information

Publications8

  1. pmc Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling
    Rohit Mittal
    Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
    Proc Natl Acad Sci U S A 103:18574-9. 2006
    ....
  2. pmc The acetyltransferase activity of the bacterial toxin YopJ of Yersinia is activated by eukaryotic host cell inositol hexakisphosphate
    Rohit Mittal
    Medical Research Council MRC, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    J Biol Chem 285:19927-34. 2010
    ....
  3. pmc FCHo proteins are nucleators of clathrin-mediated endocytosis
    William Mike Henne
    Medical Research Council, Laboratory of Molecular Biology MRC LMB, Hills Road, Cambridge CB2 0QH, UK
    Science 328:1281-4. 2010
    ..The FCHo F-BAR membrane-bending activity was required, leading to the proposal that FCHo1/2 sculpt the initial bud site and recruit the clathrin machinery for CCV formation...
  4. pmc Cooperative recruitment of dynamin and BIN/amphiphysin/Rvs (BAR) domain-containing proteins leads to GTP-dependent membrane scission
    Michael Meinecke
    Laboratory of Molecular Biology, Medical Research Council, Hills Road, Cambridge CB2 0QH, United Kingdom
    J Biol Chem 288:6651-61. 2013
    ..Furthermore, GTP-dependent membrane scission by dynamin was dramatically elevated by BAR domain proteins. Thus, BAR domain proteins and dynamin act in synergy in membrane recruitment and GTP-dependent vesicle scission...
  5. ncbi request reprint Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature
    William Mike Henne
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB1 0QH, United Kingdom
    Structure 15:839-52. 2007
    ..This structure shows a distant relationship to curvature-sensing BAR modules, and suggests how similar coiled-coil architectures in the BAR superfamily have evolved to expand the repertoire of membrane-sculpting possibilities...
  6. ncbi request reprint Effects of remote mutation on the autolysis of HIV-1 PR: X-ray and NMR investigations
    Mukesh Kumar
    Solid State Physics Division, Bhabha Atomic Research Centre, Mumbai 400 005, India
    Biochem Biophys Res Commun 294:395-401. 2002
    ..This provides a rationale for the effects of remote mutations on the activity and drug resistance of the enzyme...
  7. ncbi request reprint Structural characterization of the large soluble oligomers of the GTPase effector domain of dynamin
    Jeetender Chugh
    Department of Chemical Sciences, Tata Institute of Fundamental Reseach, Mumbai, India
    FEBS J 273:388-97. 2006
    ....
  8. pmc Local structural preferences and dynamics restrictions in the urea-denatured state of SUMO-1: NMR characterization
    Ashutosh Kumar
    Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai, India
    Biophys J 90:2498-509. 2006
    ..The implications of these observations for the early folding events starting from the urea-denatured state of activated SUMO-1 have been discussed...