P Mitchell

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi request reprint Unruptured intracranial aneurysms: benign curiosity or ticking bomb?
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    Lancet Neurol 3:85-92. 2004
  2. pmc Regional differences in outcome from subarachnoid haemorrhage: comparative audit
    P Mitchell
    Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE
    BMJ 328:1234-5. 2004
  3. ncbi request reprint Reliability assessment of computerized tomography scanning measurements in intracerebral hematoma
    Parameswaran S Bhattathiri
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom
    Neurosurg Focus 15:E6. 2003
  4. ncbi request reprint Surgery for malignant gliomas: mechanistic reasoning and slippery statistics
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK
    Lancet Neurol 4:413-22. 2005
  5. ncbi request reprint Side errors in neurosurgery
    P Mitchell
    Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle General Hospital, UK
    Acta Neurochir (Wien) 148:1289-92; discussion 1292. 2006
  6. pmc Update on the Surgical Trial in Lobar Intracerebral Haemorrhage (STICH II): statistical analysis plan
    Barbara A Gregson
    STICH Office, Neurosurgical Trials Unit, Newcastle University, 3 4 Claremont Terrace, Newcastle upon Tyne, NE2 4AE, UK
    Trials 13:222. 2012
  7. pmc Surgical trial in traumatic intracerebral hemorrhage (STITCH(Trauma)): study protocol for a randomized controlled trial
    Barbara A Gregson
    Neurosurgical Trials Unit, 3 4 Claremont Terrace, Newcastle University, Newcastle upon Tyne, NE2 4AE, UK
    Trials 13:193. 2012
  8. pmc Surgical trial in lobar intracerebral haemorrhage (STICH II) protocol
    A David Mendelow
    STICH Office, Neurosurgical Trials Unit, Newcastle University, 3 4 Claremont Terrace, Newcastle upon Tyne, NE2 4AE, UK
    Trials 12:124. 2011
  9. ncbi request reprint Regional differences in outcome from subarachnoid haemorrhage
    P Mitchell
    Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle General Hospital, Newcastle upon Tyne, UK
    Acta Neurochir (Wien) 147:959-64; discussion 964. 2005
  10. ncbi request reprint Blood pressure, fatigue, and the pathogenesis of aneurysmal subarachnoid hemorrhage
    Patrick Mitchell
    Neurosurgery School of Surgical and Reproductive Sciences, Newcastle University, Newcastle General Hospital, NE4 6BE Newcastle upon Tyne, UK
    Surg Neurol 66:574-80; discussion 580. 2006

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Unruptured intracranial aneurysms: benign curiosity or ticking bomb?
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    Lancet Neurol 3:85-92. 2004
    ..Third, in all other cases treatment with surgical clipping or coil embolisation should be advised. And finally, if surgical treatment is not feasible then medical hypotensive treatment may be a viable alternative...
  2. pmc Regional differences in outcome from subarachnoid haemorrhage: comparative audit
    P Mitchell
    Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE
    BMJ 328:1234-5. 2004
  3. ncbi request reprint Reliability assessment of computerized tomography scanning measurements in intracerebral hematoma
    Parameswaran S Bhattathiri
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom
    Neurosurg Focus 15:E6. 2003
    ..In the present study the authors determined the inter-and intraobserver variability of various parameters pertinent to CT scans obtained in patients with intracerebral hematomas (ICHs)...
  4. ncbi request reprint Surgery for malignant gliomas: mechanistic reasoning and slippery statistics
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK
    Lancet Neurol 4:413-22. 2005
    ..In this review we examine the prevailing mechanistic model and observational data; we assess how these are applied and the priorities they indicate for future research...
  5. ncbi request reprint Side errors in neurosurgery
    P Mitchell
    Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle General Hospital, UK
    Acta Neurochir (Wien) 148:1289-92; discussion 1292. 2006
    ..It is concluded that to prevent these mistakes emphasis should be placed on ensuring that the preoperative site check is completed more than on ensuring that unambiguous side information is available in the notes and imaging...
  6. pmc Update on the Surgical Trial in Lobar Intracerebral Haemorrhage (STICH II): statistical analysis plan
    Barbara A Gregson
    STICH Office, Neurosurgical Trials Unit, Newcastle University, 3 4 Claremont Terrace, Newcastle upon Tyne, NE2 4AE, UK
    Trials 13:222. 2012
    ..It is an international, multi-centre, prospective randomised parallel group trial of early surgery in patients with spontaneous lobar ICH. Outcome is measured at six months via a postal questionnaire...
  7. pmc Surgical trial in traumatic intracerebral hemorrhage (STITCH(Trauma)): study protocol for a randomized controlled trial
    Barbara A Gregson
    Neurosurgical Trials Unit, 3 4 Claremont Terrace, Newcastle University, Newcastle upon Tyne, NE2 4AE, UK
    Trials 13:193. 2012
    ..The aim of early surgery in TICH removal is to prevent secondary brain injury. There have been trials of surgery for spontaneous ICH (including the STICH II trial), but none so far of surgery for TICH...
  8. pmc Surgical trial in lobar intracerebral haemorrhage (STICH II) protocol
    A David Mendelow
    STICH Office, Neurosurgical Trials Unit, Newcastle University, 3 4 Claremont Terrace, Newcastle upon Tyne, NE2 4AE, UK
    Trials 12:124. 2011
    ..The STICH II study will establish whether a policy of earlier surgical evacuation of the haematoma in selected patients will improve outcome compared to a policy of initial conservative treatment...
  9. ncbi request reprint Regional differences in outcome from subarachnoid haemorrhage
    P Mitchell
    Department of Neurosurgery, University of Newcastle upon Tyne, Newcastle General Hospital, Newcastle upon Tyne, UK
    Acta Neurochir (Wien) 147:959-64; discussion 964. 2005
    ..Considerable concern exists about misinterpretation of such data. The issue is well illustrated by this study...
  10. ncbi request reprint Blood pressure, fatigue, and the pathogenesis of aneurysmal subarachnoid hemorrhage
    Patrick Mitchell
    Neurosurgery School of Surgical and Reproductive Sciences, Newcastle University, Newcastle General Hospital, NE4 6BE Newcastle upon Tyne, UK
    Surg Neurol 66:574-80; discussion 580. 2006
    ..We investigate the possible mechanisms of rupture to offer an explanation for this...
  11. ncbi request reprint Surgical options in ICH including decompressive craniectomy
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, England NE4 6BE, United Kingdom
    J Neurol Sci 261:89-98. 2007
    ..An important exception is ICHs arising from intracranial aneurysms where there is good evidence to support evacuation of the haematoma as well as repair of the aneurysm...
  12. doi request reprint Could late rebleeding overturn the superiority of cranial aneurysm coil embolization over clip ligation seen in the International Subarachnoid Aneurysm Trial?
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    J Neurosurg 108:437-42. 2008
    ..In the ISAT, coil embolization appears to be safer than clip ligation at 1 year, and clip occlusion has better long-term efficacy at preventing rebleeding. This leaves open the question of which is better in the longer term...
  13. ncbi request reprint Decompressive craniectomy with lattice duraplasty
    P Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    Acta Neurochir (Wien) 146:159-60. 2004
    ..Numerous cuts intersecting in a lattice pattern allow the dura to expand in a gradual and controlled manner minimising the chances of cortical laceration or venous kinking on the craniectomy edge...
  14. ncbi request reprint The significance of crossovers after randomization in the STICH trial
    K S M Prasad
    Regional Neurosciences Centre, Newcastle General Hospital, Newcastle upon Tyne, UK
    Acta Neurochir Suppl 96:61-4. 2006
    ..The Surgical Trial in Intracerebral Haemorrhage (STICH) found no difference in outcomes between patients randomized to surgical or conservative treatment...
  15. ncbi request reprint Decompressive craniectomy in traumatic brain injury: the randomized multicenter RESCUEicp study (www.RESCUEicp.com)
    P J Hutchinson
    Department of Neurosurgery, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Acta Neurochir Suppl 96:17-20. 2006
    ..We describe the concept of decompressive craniectomy in traumatic brain injury and the rationale and protocol of the RESCUEicp study...
  16. ncbi request reprint Prevention of intracerebral haemorrhage
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    Curr Drug Targets 8:832-8. 2007
    ..Although there is a wide range of such lesions available treatments come down to three modalities. These are surgical excision, stereotactic radiosurgery and endovascular embolisation...
  17. pmc Risk analysis of treatment of unruptured aneurysms
    P Mitchell
    Department of Neurosurgery, Royal Hallamshire Hospital, Sheffield S10 2JF, UK
    J Neurol Neurosurg Psychiatry 68:577-80. 2000
    ..To calculate the expected number of life-years saved by surgical treatment of unruptured intracranial aneurysms at ages over 20 years...
  18. ncbi request reprint Predicting the risk of rupture of intracranial aneurysms based on anatomical location
    G Clarke
    Biomedical Sciences, Faculty of Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne, UK
    Acta Neurochir (Wien) 147:259-63; discussion 263. 2005
    ..The ISUIA post hoc hypothesis fails when tested on these data and the ISUIA data should be re-analysed with posterior communicating artery aneurysms grouped with the anterior circulation where they more traditionally belong...
  19. pmc Risk-benefit analysis of the treatment of unruptured intracranial aneurysms
    R R Vindlacheruvu
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    J Neurol Neurosurg Psychiatry 76:234-9. 2005
    ..To determine under what circumstances repair of unruptured intracranial aneurysms may be beneficial...
  20. ncbi request reprint Supraorbital eyebrow minicraniotomy for anterior circulation aneurysms
    Patrick Mitchell
    Department of Neurosurgery, Newcastle General Hospital, NE4 6BE Newcastle, UK
    Surg Neurol 63:47-51; discussion 51. 2005
    ..We report our experience with the minimally invasive supraorbital approach to aneurysms of the ipsilateral anterior cerebral circulation...
  21. ncbi request reprint In-vivo measurement of brain relaxation after lobectomies
    N Mukerji
    Department of Neurosurgery, Regional Neurosciences Centre, Newcastle General Hospital, Newcastle upon Tyne, UK
    Br J Neurosurg 20:150-2. 2006
    ..25(0.76 - 6.64) ml/h in this study. Further studies using more frequent data collection would allow for more accurate definition of the rate of relaxation...
  22. pmc Detection of subarachnoid haemorrhage with magnetic resonance imaging
    P Mitchell
    Department of Neurosurgery, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    J Neurol Neurosurg Psychiatry 70:205-11. 2001
    ..To measure the sensitivity and specificity of five MRI sequences to subarachnoid haemorrhage...
  23. ncbi request reprint Failure testing cerebral arteries: are branch points weaker than unbranched vessels?
    P Mitchell
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    Br J Neurosurg 16:578-82. 2002
    ..971 bar). This difference was significant with p < 0.001. Bursting pressure was found to decline at 2% per year of age. This figure was different from 0 with p = 0.003...
  24. ncbi request reprint A stereoscope for image-guided surgery
    P Mitchell
    Department of Neurosurgery, Royal Hallamshire Hospital Sheffield, UK
    Br J Neurosurg 16:261-6; discussion 267-8. 2002
    ..The instrument was used in six cases. A lateral accuracy of 10-15 mm was achieved and a depth accuracy of 5-10 mm...
  25. doi request reprint Using telephone logs instead of databases to accurately estimate neurosurgical on-call workload
    N Mukerji
    Department of Neurosurgery, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Neurosurg 27:344-7. 2013
    ..We hypothesize that these databases underestimate the workload and propose the use of the number of telephone calls to the on-call registrar as an easily obtainable and valid measure of workload...
  26. ncbi request reprint Effect of awake Carotid Endarterectomy under local anaesthesia on peri-operative blood pressure: blood pressure is normalised when carotid stenosis is treated under local anaesthesia
    P S Bhattathiri
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    Acta Neurochir (Wien) 147:839-45. 2005
    ....
  27. ncbi request reprint Proximal migration of a lumboperitoneal unishunt system
    D Rodrigues
    Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK
    J Clin Neurosci 12:838-41. 2005
    ..A rare case of proximal migration of LP shunt into the quadrigeminal cistern is also reported...