Robert F Miller

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Cardiac disease in adolescents with delayed diagnosis of vertically acquired HIV infection
    Robert F Miller
    Research Department of Infection and Population Health, Institute of Epidemiology and Healthcare, University College London, Mortimer Market Centre, London WC1E 6JB, United Kingdom
    Clin Infect Dis 56:576-82. 2013
  2. doi request reprint Pneumocystis pneumonia associated with human immunodeficiency virus
    Robert F Miller
    Research Department of Infection and Population Health, University College London, London WC1E 6JB, UK
    Clin Chest Med 34:229-41. 2013
  3. ncbi request reprint Isolates of Pneumocystis jirovecii from Harare show high genotypic similarity to isolates from London at the superoxide dismutase locus
    Robert F Miller
    Centre for Sexual Health and HIV Research, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, London WC1E 6AU, UK
    Trans R Soc Trop Med Hyg 99:202-6. 2005
  4. pmc Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis
    Anil Pooran
    Division of Infection and Immunity, Centre for Infectious Diseases and International Health, University College London Medical School, University College London, 43 Cleveland Street, London W1T 4JF, UK
    BMC Pulm Med 10:7. 2010
  5. pmc Adherent human alveolar macrophages exhibit a transient pro-inflammatory profile that confounds responses to innate immune stimulation
    Gillian S Tomlinson
    Infection and Immunity, University College London, London, United Kingdom
    PLoS ONE 7:e40348. 2012
  6. pmc Genome-wide innate immune responses in HIV-1-infected macrophages are preserved despite attenuation of the NF-kappa B activation pathway
    Mahdad Noursadeghi
    Infection and Immunity, University College London, London, United Kingdom
    J Immunol 182:319-28. 2009
  7. pmc Transcriptional profiling of innate and adaptive human immune responses to mycobacteria in the tuberculin skin test
    Gillian S Tomlinson
    Infection and Immunity, University College London, London, UK
    Eur J Immunol 41:3253-60. 2011
  8. pmc HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation
    Jhen Tsang
    Division of Infection and Immunity, University College London, London, UK
    AIDS 23:2255-63. 2009
  9. ncbi request reprint Multilocus genotyping of Pneumocystis jirovecii from adult HIV-infected patients with Pneumocystis pneumonia
    Robert F Miller
    Department of Sexually Transmitted Diseases, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, University College London, United Kingdom
    J Eukaryot Microbiol 50:654-5. 2003
  10. pmc Early predictors of mortality from Pneumocystis jirovecii pneumonia in HIV-infected patients: 1985-2006
    Peter D Walzer
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, University College London, London, United Kingdom
    Clin Infect Dis 46:625-33. 2008

Collaborators

Detail Information

Publications23

  1. pmc Cardiac disease in adolescents with delayed diagnosis of vertically acquired HIV infection
    Robert F Miller
    Research Department of Infection and Population Health, Institute of Epidemiology and Healthcare, University College London, Mortimer Market Centre, London WC1E 6JB, United Kingdom
    Clin Infect Dis 56:576-82. 2013
    ..We investigated the characteristics of cardiac disease among adolescents with HIV infection diagnosed in late childhood who were receiving ambulatory HIV care in Harare, Zimbabwe...
  2. doi request reprint Pneumocystis pneumonia associated with human immunodeficiency virus
    Robert F Miller
    Research Department of Infection and Population Health, University College London, London WC1E 6JB, UK
    Clin Chest Med 34:229-41. 2013
    ..Trimethoprim-sulfamethoxazole remains the preferred first-line treatment regimen. In the era of ART, mortality from PCP is approximately 10% to 12%. The optimal time to start ART in a patient with PCP remains uncertain...
  3. ncbi request reprint Isolates of Pneumocystis jirovecii from Harare show high genotypic similarity to isolates from London at the superoxide dismutase locus
    Robert F Miller
    Centre for Sexual Health and HIV Research, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, London WC1E 6AU, UK
    Trans R Soc Trop Med Hyg 99:202-6. 2005
    ..jirovecii obtained from patients in London, UK was observed. These data provide additional support for the hypothesis that P. jirovecii is genetically indistinguishable in isolates from geographically diverse locations...
  4. pmc Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis
    Anil Pooran
    Division of Infection and Immunity, Centre for Infectious Diseases and International Health, University College London Medical School, University College London, 43 Cleveland Street, London W1T 4JF, UK
    BMC Pulm Med 10:7. 2010
    ..tb...
  5. pmc Adherent human alveolar macrophages exhibit a transient pro-inflammatory profile that confounds responses to innate immune stimulation
    Gillian S Tomlinson
    Infection and Immunity, University College London, London, United Kingdom
    PLoS ONE 7:e40348. 2012
    ..Moreover, despite the prevailing view that AM have an anti-inflammatory bias, our data clearly show that they can adopt a striking pro-inflammatory phenotype, and may have greater capacity for presentation of exogenous antigens than MDM...
  6. pmc Genome-wide innate immune responses in HIV-1-infected macrophages are preserved despite attenuation of the NF-kappa B activation pathway
    Mahdad Noursadeghi
    Infection and Immunity, University College London, London, United Kingdom
    J Immunol 182:319-28. 2009
    ..Unexpectedly, our data suggest innate immune responses are broadly preserved with limited exceptions, and pave the way for further study of the complex relationship between HIV-1 and immunological pathways within macrophages...
  7. pmc Transcriptional profiling of innate and adaptive human immune responses to mycobacteria in the tuberculin skin test
    Gillian S Tomlinson
    Infection and Immunity, University College London, London, UK
    Eur J Immunol 41:3253-60. 2011
    ..These data provide new insights into complex multifaceted responses within the TST, with much greater sensitivity than previous clinical or histological assessments...
  8. pmc HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation
    Jhen Tsang
    Division of Infection and Immunity, University College London, London, UK
    AIDS 23:2255-63. 2009
    ..In view of HIV-1 tropism for macrophages, which can be activated via pattern recognition receptors to trigger antimicrobial defences, we investigated innate immune responses to HIV-1 by monocyte-derived macrophages...
  9. ncbi request reprint Multilocus genotyping of Pneumocystis jirovecii from adult HIV-infected patients with Pneumocystis pneumonia
    Robert F Miller
    Department of Sexually Transmitted Diseases, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, University College London, United Kingdom
    J Eukaryot Microbiol 50:654-5. 2003
  10. pmc Early predictors of mortality from Pneumocystis jirovecii pneumonia in HIV-infected patients: 1985-2006
    Peter D Walzer
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, University College London, London, United Kingdom
    Clin Infect Dis 46:625-33. 2008
    ..Previous studies of PCP that identified case-fatality risk factors involved small numbers of patients, were performed over few years, and often focused on patients who were admitted to the intensive care unit...
  11. ncbi request reprint HIV infection presenting in older children and adolescents: a case series from Harare, Zimbabwe
    Rashida A Ferrand
    Mortimer Market Centre, Camden Primary Care Trust, London WC1E 6AU, UK
    Clin Infect Dis 44:874-8. 2007
    ..We investigated social and clinical features in patients of this age group presenting to a HIV treatment clinic with special adolescent services in Harare, Zimbabwe...
  12. ncbi request reprint A need for standardized definitions for clinical studies of Pneumocystis
    Robert F Miller
    Centre for Sexual Health and HIV Research, Department of Population Sciences and Primary Care, Royal Free and University College Medical School, University College London, London, United Kingdom
    J Eukaryot Microbiol 53:S87-8. 2006
  13. ncbi request reprint A declining CD4 count and diagnosis of HIV-associated Hodgkin lymphoma: do prior clinical symptoms and laboratory abnormalities aid diagnosis?
    Ravindra K Gupta
    Division of Infection and Immunity, University College London, London, United Kingdom University College London Hospitals NHS Foundation Trust, London, United Kingdom
    PLoS ONE 9:e87442. 2014
    ..In an era of economic austerity monitoring the efficacy of cART by CD4 counts may no longer be required where CD4 count>350 cells/┬Ál and viral load is suppressed (<50 copies/ml)...
  14. ncbi request reprint Monocyte derived dendritic cells from HIV-1 infected individuals partially reconstitute CD4 T-cell responses
    Philippa J Newton
    Department of Immunology and Molecular Pathology, University College London, UK
    AIDS 20:171-80. 2006
    ..The study tests the hypothesis that monocyte derived dendritic cells from HIV-1 infected individuals are normal and can restore impaired CD4 T-cell antigen specific responses...
  15. pmc Quantitative imaging assay for NF-kappaB nuclear translocation in primary human macrophages
    Mahdad Noursadeghi
    Department of Immunology and Molecular Pathology, University College London, Windeyer Building, 46 Cleveland Street, W1T 4JF London, UK
    J Immunol Methods 329:194-200. 2008
    ....
  16. ncbi request reprint Efficacy of boosted protease inhibitor monotherapy in patients with complex medical problems
    Nigel J Garrett
    Mortimer Market Centre, London, UK
    AIDS 21:1821-3. 2007
    ..During follow-up, at median (range) = 50 (8-156) weeks, no patient had an opportunistic illness; one patient developed new PI mutations after 48 weeks. These very preliminary data need further confirmation on a larger scale...
  17. ncbi request reprint Problems of developing molecular diagnostic tests for opportunistic pathogens: the example of Pneumocystis jirovecii
    Jim F Huggett
    Centre for Infectious Diseases and International Health, University College London, London, United Kingdom
    J Eukaryot Microbiol 53:S85-6. 2006
  18. ncbi request reprint HIV-1 infection of mononuclear phagocytic cells: the case for bacterial innate immune deficiency in AIDS
    Mahdad Noursadeghi
    Department of Immunology and Molecular Pathology, University College London, UK
    Lancet Infect Dis 6:794-804. 2006
    ..HIV-mediated injury to bacterial innate immunity provides an experimental paradigm that could broaden our overall understanding of innate immunity and be used to study responses to pathogens other than bacteria...
  19. ncbi request reprint Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count
    Keertan Dheda
    Centre for Infectious Diseases and International Health, Department of Population Sciences and Primary Care, Royal Free and University College Medical School, University College London, London, UK
    AIDS 19:2038-41. 2005
    ..ELISPOT test performance appears to be independent of HIV-associated immunosuppression...
  20. pmc Differential susceptibility of PCR reactions to inhibitors: an important and unrecognised phenomenon
    Jim F Huggett
    Centre for Infectious Diseases and International Health, Windeyer Institute for Medical Sciences, 46 Cleveland Street, University College London, London, W1T 4JF, UK
    BMC Res Notes 1:70. 2008
    ..To test this assumption we performed inhibition assessment on DNA extracts from human urine samples, fresh urine and EDTA using different PCR reactions...
  21. doi request reprint The response of HIV-associated lymphadenopathic Kaposi sarcoma to highly active antiretroviral therapy evaluated by 18F-FDG PET/CT
    Satveer K Mankia
    T8, University College London Hospitals, Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London, London, United Kingdom
    Clin Nucl Med 37:692-3. 2012
    ..Chemotherapy was initiated, and the patient achieved a complete clinical, PET/CT, and virological response. PET/CT enabled monitoring of treatment response and led to changes in management...
  22. ncbi request reprint Methaemoglobinaemia causing progressive dyspnoea and cyanosis during treatment of Pneumocystis jirovecii pneumonia
    Matthew Hamill
    Department of Genito Urinary Medicine, Mortimer Market Centre, Camden Primary Care Trust, London, UK
    Int J STD AIDS 18:577-8. 2007
    ..He was found to have 11.4% methaemoglobinaemia and recovered with conservative management...
  23. pmc Genotypes of Pneumocystis jiroveci isolates obtained in Harare, Zimbabwe, and London, United Kingdom
    Robert F Miller
    Department of Sexually Transmitted Diseases, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, University College London, London WC1E 6AU, United Kingdom
    Antimicrob Agents Chemother 47:3979-81. 2003
    ..At the dihydropteroate synthase (DHPS) locus, there was evidence of selection pressure from sulfa drug exposure, and reversal of DHPS genotype ratios occurred when selection pressure was absent or was removed...