István Miklós

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint MCMC genome rearrangement
    István Miklós
    Department of Statistics, University of Oxford, Oxford, UK
    Bioinformatics 19:ii130-7. 2003
  2. ncbi request reprint A "Long Indel" model for evolutionary sequence alignment
    I Miklos
    Department of Statistics, University of Oxford, Oxford, UK
    Mol Biol Evol 21:529-40. 2004
  3. pmc How reliably can we predict the reliability of protein structure predictions?
    István Miklós
    Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG Oxford, UK
    BMC Bioinformatics 9:137. 2008
  4. pmc Bayesian coestimation of phylogeny and sequence alignment
    Gerton Lunter
    Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK
    BMC Bioinformatics 6:83. 2005
  5. doi request reprint StatAlign: an extendable software package for joint Bayesian estimation of alignments and evolutionary trees
    Adám Novák
    Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG Oxford, UK
    Bioinformatics 24:2403-4. 2008
  6. pmc BigFoot: Bayesian alignment and phylogenetic footprinting with MCMC
    Rahul Satija
    Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG Oxford, UK
    BMC Evol Biol 9:217. 2009
  7. pmc Reticular alignment: a progressive corner-cutting method for multiple sequence alignment
    Adrienn Szabó
    Computer and Automation Research Institute, Hungarian Academy of Sciences, Lágymányosi u 11, 1111 Budapest, Hungary
    BMC Bioinformatics 11:570. 2010
  8. pmc Co-transcriptional folding is encoded within RNA genes
    Irmtraud M Meyer
    University of Oxford, Oxford OX1 3QB, UK
    BMC Mol Biol 5:10. 2004

Collaborators

Detail Information

Publications8

  1. ncbi request reprint MCMC genome rearrangement
    István Miklós
    Department of Statistics, University of Oxford, Oxford, UK
    Bioinformatics 19:ii130-7. 2003
    ..Moreover, different type of mutations happen with different rates, and it is not clear how to weight them in a distance based approach...
  2. ncbi request reprint A "Long Indel" model for evolutionary sequence alignment
    I Miklos
    Department of Statistics, University of Oxford, Oxford, UK
    Mol Biol Evol 21:529-40. 2004
    ..To this effect, we introduce a "trajectory likelihood" algorithm (Appendix A). We anticipate that this algorithm will be useful in more general contexts, such as Markov Chain Monte Carlo simulations...
  3. pmc How reliably can we predict the reliability of protein structure predictions?
    István Miklós
    Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG Oxford, UK
    BMC Bioinformatics 9:137. 2008
    ..However, sometimes all methods fail to predict the correct alignment, because the evolutionary signal is too weak to find the homologous parts due to the large number of mutations that separate the sequences...
  4. pmc Bayesian coestimation of phylogeny and sequence alignment
    Gerton Lunter
    Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK
    BMC Bioinformatics 6:83. 2005
    ..Whether the main interest be in sequence alignment or phylogeny, a major goal of computational biology is the co-estimation of both...
  5. doi request reprint StatAlign: an extendable software package for joint Bayesian estimation of alignments and evolutionary trees
    Adám Novák
    Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG Oxford, UK
    Bioinformatics 24:2403-4. 2008
    ..It is easy to add new substitution models to the software package as plugins. The samples from the Markov chain can be summarized in several ways, and new postprocessing plugins may also be installed...
  6. pmc BigFoot: Bayesian alignment and phylogenetic footprinting with MCMC
    Rahul Satija
    Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG Oxford, UK
    BMC Evol Biol 9:217. 2009
    ..Our method utilized standard dynamic programming hidden markov model algorithms to analyze up to four sequences...
  7. pmc Reticular alignment: a progressive corner-cutting method for multiple sequence alignment
    Adrienn Szabó
    Computer and Automation Research Institute, Hungarian Academy of Sciences, Lágymányosi u 11, 1111 Budapest, Hungary
    BMC Bioinformatics 11:570. 2010
    ..The program contains a threshold parameter on which the size of the network depends. The larger the threshold parameter and thus the network, the deeper the search in the alignment space for better scored alignments...
  8. pmc Co-transcriptional folding is encoded within RNA genes
    Irmtraud M Meyer
    University of Oxford, Oxford OX1 3QB, UK
    BMC Mol Biol 5:10. 2004
    ..Dedicated experiments with individual RNA molecules have shown that RNA folds while it is being transcribed and that its correct folding can also depend on the proper speed of transcription...