Sarah Meehan

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc The interaction of alphaB-crystallin with mature alpha-synuclein amyloid fibrils inhibits their elongation
    Christopher A Waudby
    University of Cambridge, United Kingdom
    Biophys J 98:843-51. 2010
  2. pmc Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation
    Sarah L Shammas
    Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
    Biophys J 101:1681-9. 2011
  3. pmc Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass
    Tuomas P J Knowles
    Nanoscience Centre, University of Cambridge, JJ Thomson Avenue, Cambridge, United Kingdom
    Proc Natl Acad Sci U S A 104:10016-21. 2007
  4. ncbi request reprint Twisting transition between crystalline and fibrillar phases of aggregated peptides
    Tuomas P J Knowles
    Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
    Phys Rev Lett 109:158101. 2012
  5. ncbi request reprint Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation
    Sarah Meehan
    Biological Physics Group, Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge CB3 0HE, United Kingdom
    J Biol Chem 279:3413-9. 2004
  6. pmc The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila
    Jenna M Gregory
    Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 7:e31899. 2012
  7. pmc Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation
    Beinan Liu
    Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust Medical Research Council Building, Hills Road, Cambridge CB2 0XY, United Kingdom
    J Biol Chem 286:4248-56. 2011

Detail Information

Publications7

  1. pmc The interaction of alphaB-crystallin with mature alpha-synuclein amyloid fibrils inhibits their elongation
    Christopher A Waudby
    University of Cambridge, United Kingdom
    Biophys J 98:843-51. 2010
    ....
  2. pmc Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation
    Sarah L Shammas
    Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
    Biophys J 101:1681-9. 2011
    ....
  3. pmc Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass
    Tuomas P J Knowles
    Nanoscience Centre, University of Cambridge, JJ Thomson Avenue, Cambridge, United Kingdom
    Proc Natl Acad Sci U S A 104:10016-21. 2007
    ....
  4. ncbi request reprint Twisting transition between crystalline and fibrillar phases of aggregated peptides
    Tuomas P J Knowles
    Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
    Phys Rev Lett 109:158101. 2012
    ....
  5. ncbi request reprint Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation
    Sarah Meehan
    Biological Physics Group, Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge CB3 0HE, United Kingdom
    J Biol Chem 279:3413-9. 2004
    ..The ability of the crystallins to convert into fibrils under destabilizing conditions suggests that this process could contribute to the development of cataract with aging...
  6. pmc The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila
    Jenna M Gregory
    Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 7:e31899. 2012
    ....
  7. pmc Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation
    Beinan Liu
    Department of Medicine, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust Medical Research Council Building, Hills Road, Cambridge CB2 0XY, United Kingdom
    J Biol Chem 286:4248-56. 2011
    ..These data support the hypothesis that iron delays the formation of well ordered aggregates of Aβ and so promotes its toxicity in Alzheimer disease...