H McQuay

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford, UK
    Arthritis Res Ther 7:R1046-51. 2005
  2. pmc Indirect comparison of interventions using published randomised trials: systematic review of PDE-5 inhibitors for erectile dysfunction
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe NHS Trust, The Churchill, Headington, Oxford, OX37LJ, UK
    BMC Urol 5:18. 2005
  3. pmc Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of clinical trial reports
    R A Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, UK
    BMC Urol 2:6. 2002
  4. pmc Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, UK
    BMC Musculoskelet Disord 8:73. 2007
  5. pmc Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Musculoskelet Disord 7:79. 2006
  6. pmc Pregabalin in fibromyalgia--responder analysis from individual patient data
    Sebastian Straube
    Department of Occupational and Social Medicine, University of Gottingen, Waldweg 37 B, D 37073 Gottingen, Germany
    BMC Musculoskelet Disord 11:150. 2010
  7. pmc Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis
    Lorna Mason
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Musculoskelet Disord 5:28. 2004
  8. pmc Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg
    L A Smith
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford, UK
    BMC Med Res Methodol 1:1. 2001
  9. pmc Pooling data for number needed to treat: no problems for apples
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford, UK
    BMC Med Res Methodol 2:2. 2002
  10. pmc Prevalence of anaemia in older persons: systematic review
    Helen Gaskell
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospitals, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Geriatr 8:1. 2008

Detail Information

Publications56

  1. pmc Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford, UK
    Arthritis Res Ther 7:R1046-51. 2005
    ..Because most trials were short, less than four weeks, and because few titrated the dose, these results have limited applicability to longer-term use of opioids in clinical practice. Suggestions for improved studies are made...
  2. pmc Indirect comparison of interventions using published randomised trials: systematic review of PDE-5 inhibitors for erectile dysfunction
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe NHS Trust, The Churchill, Headington, Oxford, OX37LJ, UK
    BMC Urol 5:18. 2005
    ..Valid indirect comparisons with a common comparator must examine equivalent doses, similar duration, similar populations, with the same outcomes reported in the same way...
  3. pmc Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of clinical trial reports
    R A Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, UK
    BMC Urol 2:6. 2002
    ..Evaluation of company clinical trial reports could provide information for meta-analysis at the commercial introduction of a new technology...
  4. pmc Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, UK
    BMC Musculoskelet Disord 8:73. 2007
    ..We calculated the absolute risk for each effect...
  5. pmc Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Musculoskelet Disord 7:79. 2006
    ....
  6. pmc Pregabalin in fibromyalgia--responder analysis from individual patient data
    Sebastian Straube
    Department of Occupational and Social Medicine, University of Gottingen, Waldweg 37 B, D 37073 Gottingen, Germany
    BMC Musculoskelet Disord 11:150. 2010
    ..A consensus group has defined what constitutes minimal, moderate, and substantial benefit based on pain intensity and Patient Global Impression of Change scores...
  7. pmc Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis
    Lorna Mason
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Musculoskelet Disord 5:28. 2004
    ..More trials, a better understanding of trial quality and bias, and a reclassification of certain drugs necessitate a new review...
  8. pmc Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg
    L A Smith
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford, UK
    BMC Med Res Methodol 1:1. 2001
    ..This neglects other types of high quality information. This review explores using different information for the combination of paracetamol 1000 mg and codeine 60 mg in acute postoperative pain...
  9. pmc Pooling data for number needed to treat: no problems for apples
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford, UK
    BMC Med Res Methodol 2:2. 2002
    ....
  10. pmc Prevalence of anaemia in older persons: systematic review
    Helen Gaskell
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospitals, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Geriatr 8:1. 2008
    ..Anaemia may be one such problem. We report on the prevalence of anaemia in cohorts of elderly people in the general population. The presence of anaemia is associated with a worse prognosis for both morbidity and mortality...
  11. pmc Mortality with upper gastrointestinal bleeding and perforation: effects of time and NSAID use
    Sebastian Straube
    Department of Occupational and Social Medicine, University of Gottingen, Gottingen, Germany
    BMC Gastroenterol 9:41. 2009
    ..Better treatment is likely to have reduced mortality. An estimate of mortality is helpful in explaining to patients the risks of therapy, especially with NSAIDs...
  12. pmc Topical NSAIDs for acute pain: a meta-analysis
    Lorna Mason
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford, OX3 7LJ, UK
    BMC Fam Pract 5:10. 2004
    ..More trials, a better understanding of trial quality and bias, and a reclassification of certain drugs necessitate a new review...
  13. pmc Systematic review of the use of honey as a wound dressing
    O A Moore
    Pain Research Unit and Nuffield Department of Anaesthetics, University of Oxford, Oxford, Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    BMC Complement Altern Med 1:2. 2001
    ..To investigate topical honey in superficial burns and wounds though a systematic review of randomised controlled trials...
  14. pmc Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford OX3 7LJ, UK
    Arthritis Res Ther 10:R39. 2008
    ..We investigated whether dichotomous responder analysis provides a more informative interpretation of drug efficacy...
  15. pmc Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: systematic review of randomized trials using autologous chromium-labelled erythrocytes
    R Andrew Moore
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospitals, The Churchill, Headington, Oxford, OX3 7LJ, UK
    Arthritis Res Ther 10:R7. 2008
    ....
  16. pmc What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe NHS Trust, The Churchill, Headington, Oxford OX3 7LJ, UK
    Arthritis Res Ther 10:R20. 2008
    ....
  17. pmc Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe NHS Trust, Oxford, UK
    Arthritis Res Ther 7:R644-65. 2005
    ..Adverse event information is clearly presented in company clinical trial reports, which are an ideal source of information for systematic review and meta-analysis...
  18. doi Acute pain: combination treatments and how we measure their efficacy
    H J McQuay
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford OX3 7LJ, UK
    Br J Anaesth 101:69-76. 2008
    ....
  19. pmc Placebo
    H J McQuay
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Oxford OX3 7LJ, UK
    Postgrad Med J 81:155-60. 2005
    ....
  20. ncbi Evaluating analgesia: the challenges
    Henry J McQuay
    Pain Research, Nuffield Department of Anesthetics, University of Oxford, The Churchill Oxford Radcliffe Hospital, Headington, UK
    Am J Ther 9:179-87. 2002
    ..Databases of patient experience, with all the caveats, may be the most reliable data from which to work...
  21. doi Evidence-based medicine: what is the evidence that it has made a difference?
    Henry McQuay
    University of Oxford, UK
    Palliat Med 25:394-7. 2011
    ..This we think is correct. The process of systematic review of a topic throws up the deficits in trial methods and the lacunae in the data, and this then can show the way forward...
  22. pmc Dose-response in direct comparisons of different doses of aspirin, ibuprofen and paracetamol (acetaminophen) in analgesic studies
    Henry J McQuay
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Churchill Hospital, Oxford, UK
    Br J Clin Pharmacol 63:271-8. 2007
    ..Establishing the dose-response relationship for clinically useful doses of aspirin, ibuprofen and paracetamol has been difficult. Indirect comparison from meta-analysis is compromised by too little information at some doses...
  23. ncbi Neuropathic pain: evidence matters
    Henry J McQuay
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    Eur J Pain 6:11-8. 2002
    ..One of the hallmarks of neuropathic pain is poor or incomplete relief with opioids. As with so many things in medicine, there is nothing novel in this realization, as the Tolstoy quotation shows...
  24. pmc Management of Chronic Pain: Help and hope at the bottom of the pile
    Henry McQuay
    Pain Relief Unit, The Churchill, Headington, Oxford OX3 7LJ
    BMJ 336:954-5. 2008
  25. ncbi Opioids in pain management
    H McQuay
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Oxford Radcliffe Hospital, Headington, UK
    Lancet 353:2229-32. 1999
    ..The justification for this focus is that patients with chronic pain may suffer longer and unnecessarily if we prescribe and legislate badly...
  26. ncbi Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: verification from independent data
    A Moore
    Oxford Pain Relief Unit, University of Oxford, Oxford Radcliffe Hospital, Headington, UK
    Pain 69:127-30. 1997
    ..Showing that dichotomous data can reliably be derived from mean data in acute pain studies enables data published as means to be used for quantitative systematic reviews which require data in dichotomous form...
  27. ncbi Paracetamol with and without codeine in acute pain: a quantitative systematic review
    A Moore
    Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, UK
    Pain 70:193-201. 1997
    ..This was an NNT for adding codeine 60 mg of 9.1 (5.8-24). The results confirm that paracetamol is an effective analgesic, and that codeine 60 mg added to paracetamol produces worthwhile additional pain relief even in single oral doses...
  28. pmc Systematic review of topical capsaicin for the treatment of chronic pain
    Lorna Mason
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Headington, Oxford OX3 7LJ
    BMJ 328:991. 2004
    ..To determine the efficacy and safety of topically applied capsaicin for chronic pain from neuropathic or musculoskeletal disorders...
  29. pmc Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain
    Lorna Mason
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Headington, Oxford OX3 7LJ
    BMJ 328:995. 2004
    ..To determine the efficacy and safety of topical rubefacients containing salicylates in acute and chronic pain...
  30. ncbi Combination analgesic efficacy: individual patient data meta-analysis of single-dose oral tramadol plus acetaminophen in acute postoperative pain
    Jayne E Edwards
    Pain Research and Nuffield Department of Anesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford, United Kingdom
    J Pain Symptom Manage 23:121-30. 2002
    ..Common adverse effects were dizziness, drowsiness, nausea, vomiting, and headache. In sum, this meta-analysis demonstrated analgesic superiority of the combination drug over its components, without additional toxicity...
  31. ncbi Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: use of pain intensity and visual analogue scales
    A Moore
    Oxford Pain Relief Unit, University of Oxford, UK
    Pain 69:311-5. 1997
    ..Showing that dichotomous data can reliably be derived from mean SPID, VAS-SPID and VAS-TOTPAR as well as TOTPAR data in previously published acute pain studies makes much more information accessible for meta-analysis...
  32. ncbi Meta-analysis of single dose oral tramadol plus acetaminophen in acute postoperative pain
    H McQuay
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford, UK
    Eur J Anaesthesiol Suppl 28:19-22. 2003
    ....
  33. ncbi Outcomes in acute pain trials: systematic review of what was reported?
    Jodie Barden
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 109:351-6. 2004
    ..Most useful would be all three. Further exploration would only be possible from analysis at the individual patient level...
  34. doi Fibromyalgia: Moderate and substantial pain intensity reduction predicts improvement in other outcomes and substantial quality of life gain
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Pain 149:360-4. 2010
    ..Pain intensity reduction is a simple and effective predictor of which patients should continue treatment, and which should discontinue and try an alternative therapy...
  35. ncbi Pain and analgesic response after third molar extraction and other postsurgical pain
    Jodie Barden
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 107:86-90. 2004
    ..Systematic difference in the estimate of analgesic efficacy between dental and postsurgical pain models remains unproven, and, on balance, no major difference is likely...
  36. pmc Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports
    R Andrew Moore
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Oxford OX3 7LJ, UK
    Arthritis Res Ther 10:R53. 2008
    ..By contrast, company clinical trial reports include much more detail...
  37. ncbi Aspirin with or without an antiemetic for acute migraine headaches in adults
    Varo Kirthi
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 4:CD008041. 2010
    ..Addition of metoclopramide 10 mg improves relief of nausea and vomiting. Adverse events were mainly mild and transient, and were slightly more common with aspirin than placebo, but less common than with sumatriptan 100 mg...
  38. doi Enriched enrolment with randomised withdrawal (EERW): Time for a new look at clinical trial design in chronic pain
    Henry J McQuay
    Pain Research, Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Pain 135:217-20. 2008
  39. ncbi Bias from industry trial funding? A framework, a suggested approach, and a negative result
    Jodie Barden
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 121:207-18. 2006
    ..We propose a method based on potential conflict of interest within industry-sponsored trials. Using this method, established clinical trial results in acute pain and migraine appear to be unbiased...
  40. ncbi Efficacy and safety of valdecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials
    Jayne E Edwards
    Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ, UK
    Pain 111:286-96. 2004
    ..There were fewer gastrointestinal adverse event withdrawals and endoscopically detected ulcers. Convincing evidence of reduced major gastrointestinal adverse events could not be addressed by the trials...
  41. ncbi Single dose oral diflunisal for acute postoperative pain in adults
    Jack O Wasey
    Magdalen College, University of Oxford, High Street, Oxford, Oxfordshire, UK, OX1 4AU
    Cochrane Database Syst Rev 4:CD007440. 2010
    ..This property may be useful when regular dosing is needed, or when taking several doses of a shorter acting analgesic is impractical...
  42. pmc Enriched enrollment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review
    Sebastian Straube
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, Oxford, UK
    Br J Clin Pharmacol 66:266-75. 2008
    ..We aim to investigate whether this really is the case in trials of pregabalin and gabapentin in neuropathic pain...
  43. ncbi Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults
    Sheena Derry
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 11:CD008040. 2010
    ..Many sufferers choose not to, or are unable to, seek professional help and rely on over-the-counter analgesics. Co-therapy with an antiemetic should help to reduce nausea and vomiting commonly associated with migraine...
  44. ncbi Single dose oral codeine, as a single agent, for acute postoperative pain in adults
    Sheena Derry
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, West Wing Level 6, John Radcliffe Hospital, Oxford, Oxfordshire, UK, OX3 9DU
    Cochrane Database Syst Rev 4:CD008099. 2010
    ..Higher doses were not evaluated...
  45. ncbi Dipyrone and agranulocytosis: what is the risk?
    Jayne E Edwards
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital NHS Trust, The Churchill, OX3 7LJ, Oxford, UK
    Lancet 360:1438. 2002
  46. ncbi Pharmacological treatments for acute migraine: quantitative systematic review
    Anna D Oldman
    Pain Research, Nuffield Department of Anaesthetics, Oxford Radcliffe Hospital, University of Oxford, The Churchill, Headington, UK
    Pain 97:247-57. 2002
    ..8 for eletriptan 80mg to 8.3 for rizatriptan 5mg. It was not possible to systematically review adverse effects data. Most interventions are effective. There is considerable information on relative efficacy for a number of outcomes...
  47. doi Topical agents in the treatment of rheumatic pain
    R Andrew Moore
    Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, The Churchill, Headington, Oxford OX3 9DU, UK
    Rheum Dis Clin North Am 34:415-32. 2008
    ..The best information is for topical diclofenac. For topical capsaicin, evidence of efficacy is trivial. For topical rubefacients there is no evidence of efficacy...
  48. ncbi Five easy pieces on evidence based medicine (5). Trading benefit against harm--pain relief vs. adverse effects
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Helsinki, Finland
    Eur J Pain 6:409-12. 2002
  49. ncbi No pain, no gain: clinical excellence and scientific rigour--lessons learned from IA morphine
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care, Helsinki University Hospital, P O Box 340, Helsinki, FIN 00029 HUS, Finland
    Pain 98:269-75. 2002
    ..A minimum of 30% of the maximum possible pain intensity is needed for an analgesic effect to be detected in a study...
  50. ncbi Opioids in chronic non-cancer pain: systematic review of efficacy and safety
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Pain 112:372-80. 2004
    ..The small number of selected patients and the short follow-ups do not allow conclusions concerning problems such as tolerance and addiction...
  51. ncbi Epidemiology and treatment of neuropathic pain: the UK primary care perspective
    Gillian C Hall
    Grimsdyke House, London, UK
    Pain 122:156-62. 2006
    ..For commonly prescribed treatments, changes in therapy are less frequent when initial therapy was with antidepressants or anticonvulsants rather than conventional analgesics...
  52. ncbi Five easy pieces on evidence-based medicine (4)
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Helsinki, Finland
    Eur J Pain 6:89-93. 2002
  53. pmc Primary care incidence and treatment of four neuropathic pain conditions: a descriptive study, 2002-2005
    Gillian C Hall
    Grimsdyke House, London, UK
    BMC Fam Pract 9:26. 2008
    ..The most common first line treatments were compound analgesics. As therapeutic options have subsequently changed, this study presents updated data on incidence and prescribing patterns in neuropathic pain...
  54. ncbi Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations
    Robert H Dworkin
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Pain 9:105-21. 2008
    ..Provisional benchmarks for identifying clinically important changes in specific outcome measures that can be used for outcome studies of treatments for chronic pain are proposed...
  55. ncbi Clinically important changes-what's important and whose change is it anyway?
    Henry J McQuay
    J Pain Symptom Manage 25:395-6. 2003
  56. doi Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies
    Daniel K Kajdasz
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA
    Clin Ther 29:2536-46. 2007
    ....