R J Q McNally

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi request reprint Space-time clustering patterns in childhood solid tumours other than central nervous system tumours
    Richard J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Manchester, United Kingdom
    Int J Cancer 103:253-8. 2003
  2. ncbi request reprint Environmental factors and childhood acute leukemias and lymphomas
    Richard J Q McNally
    School of Clinical Medical Sciences, Child Health, University of Newcastle upon Tyne, UK
    Leuk Lymphoma 47:583-98. 2006
  3. ncbi request reprint Space-time clustering analyses of occurrence of cerebral palsy in Northern England for births 1991 to 2003
    Richard J Q McNally
    School of Clinical Medical Sciences, Child Health, Newcastle University, Newcastle upon Tyne, UK
    Ann Epidemiol 18:108-12. 2008
  4. doi request reprint Increasing incidence of thyroid cancer in Great Britain, 1976-2005: age-period-cohort analysis
    Richard J Q McNally
    Institute of Health and Society, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle University, Newcastle upon Tyne, UK
    Eur J Epidemiol 27:615-22. 2012
  5. pmc Small-area analyses of bone cancer diagnosed in Great Britain provide clues to aetiology
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, England, UK
    BMC Cancer 12:270. 2012
  6. pmc Space-time clustering of childhood central nervous system tumours in Yorkshire, UK
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    BMC Cancer 12:13. 2012
  7. pmc Rural to urban migration and changes in cardiovascular risk factors in Tanzania: a prospective cohort study
    Nigel Unwin
    Institute of Health and Society, Newcastle University, Newcastle, UK
    BMC Public Health 10:272. 2010
  8. pmc The epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - 2002
    Rachel Eyre
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, England, UK
    BMC Cancer 10:357. 2010
  9. pmc Sex-specific incidence and temporal trends in solid tumours in young people from Northern England, 1968-2005
    Brooke L Magnanti
    School of Clinical Medical Sciences Child Health and Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    BMC Cancer 8:89. 2008
  10. doi request reprint Space-time clustering of childhood cancer around the residence at birth
    Richard J Q McNally
    School of Clinical Medical Sciences Child Health and Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom
    Int J Cancer 124:449-55. 2009

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Space-time clustering patterns in childhood solid tumours other than central nervous system tumours
    Richard J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Manchester, United Kingdom
    Int J Cancer 103:253-8. 2003
    ..These are the first results to demonstrate space-time clustering for childhood Wilms' tumours and soft tissue sarcomas. The results are consistent with environmental exposure hypotheses, relating to locations pre-natally or peri-natally...
  2. ncbi request reprint Environmental factors and childhood acute leukemias and lymphomas
    Richard J Q McNally
    School of Clinical Medical Sciences, Child Health, University of Newcastle upon Tyne, UK
    Leuk Lymphoma 47:583-98. 2006
    ..Hodgkin lymphoma (HL) is especially associated with higher levels of socioeconomic deprivation, but breast-feeding seems to confer lower risk. This is consistent with an infection or immune-response mediated etiology for HL...
  3. ncbi request reprint Space-time clustering analyses of occurrence of cerebral palsy in Northern England for births 1991 to 2003
    Richard J Q McNally
    School of Clinical Medical Sciences, Child Health, Newcastle University, Newcastle upon Tyne, UK
    Ann Epidemiol 18:108-12. 2008
    ..Recent studies have suggested that maternal infection is involved. Indirect, but supportive, evidence for an infectious hypothesis would be provided by the finding of space-time clustering...
  4. doi request reprint Increasing incidence of thyroid cancer in Great Britain, 1976-2005: age-period-cohort analysis
    Richard J Q McNally
    Institute of Health and Society, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle University, Newcastle upon Tyne, UK
    Eur J Epidemiol 27:615-22. 2012
    ..The reasons for this increase are not well understood, but it is consistent with findings from other countries...
  5. pmc Small-area analyses of bone cancer diagnosed in Great Britain provide clues to aetiology
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, England, UK
    BMC Cancer 12:270. 2012
    ..We investigated putative associations with deprivation and population density...
  6. pmc Space-time clustering of childhood central nervous system tumours in Yorkshire, UK
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    BMC Cancer 12:13. 2012
    ..We specifically tested the aetiological hypothesis that a factor influencing geographical or temporal heterogeneity of childhood central nervous system (CNS) tumour incidence was related to exposure to a transient environmental agent...
  7. pmc Rural to urban migration and changes in cardiovascular risk factors in Tanzania: a prospective cohort study
    Nigel Unwin
    Institute of Health and Society, Newcastle University, Newcastle, UK
    BMC Public Health 10:272. 2010
    ..High levels of rural to urban migration are a feature of most African countries. Our aim was to investigate changes, and their determinants, in cardiovascular risk factors on rural to urban migration in Tanzania...
  8. pmc The epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - 2002
    Rachel Eyre
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, England, UK
    BMC Cancer 10:357. 2010
    ..There is a paucity of recent epidemiological data on bone cancers. The aim of this study was to describe incidence and survival patterns for bone cancers diagnosed during 1981 - 2002...
  9. pmc Sex-specific incidence and temporal trends in solid tumours in young people from Northern England, 1968-2005
    Brooke L Magnanti
    School of Clinical Medical Sciences Child Health and Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    BMC Cancer 8:89. 2008
    ..This updates earlier analyses from the region where sex was not considered in depth. Sex-specific analyses were carried out to determine whether sex differences might provide clues to aetiology...
  10. doi request reprint Space-time clustering of childhood cancer around the residence at birth
    Richard J Q McNally
    School of Clinical Medical Sciences Child Health and Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom
    Int J Cancer 124:449-55. 2009
    ..For leukemia, NHL and Wilms tumor there is support for exposures occurring at similar times before diagnosis. For leukemia, HL, NHL and CNS tumors, but not Wilms tumor, the findings are consistent with infectious hypotheses...
  11. doi request reprint Spatial clustering of childhood cancer in Great Britain during the period 1969-1993
    Richard J Q McNally
    School of Clinical Medical Sciences Child Health, Sir James Spence Institute, Newcastle University, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Int J Cancer 124:932-6. 2009
    ..For ALL and soft tissue sarcoma, but not Wilms tumour, common infectious agents may be likely candidates...
  12. doi request reprint Are transient environmental agents involved in the cause of primary biliary cirrhosis? Evidence from space-time clustering analysis
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, UK
    Hepatology 50:1169-74. 2009
    ..A number of specific space-time clusters were identified. In conclusion, these novel results suggest that transient environmental agents may play a role in the cause of PBC...
  13. ncbi request reprint Are early infectious exposures involved in the etiology of childhood CNS tumors?
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK
    Expert Rev Neurother 10:1663-5. 2010
    ....
  14. pmc Space-time clustering analyses of type 1 diabetes in children from north-east England: support for an infectious aetiology?
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, UK
    Environ Health 8:S14. 2009
    ....
  15. ncbi request reprint Is there a common aetiology for certain childhood malignancies? Results of cross-space-time clustering analyses
    Richard J Q McNally
    Sir James Spence Institute, Level 4, Royal Victoria Infirmary, Queen Victoria Road, Newcastle NE1 4LP, UK
    Eur J Cancer 41:2911-6. 2005
    ..In conclusion, these findings are consistent with common, possibly infectious, aetiological mechanisms for childhood leukaemia (particularly ALL) and CNS tumours (particularly astrocytoma)...
  16. ncbi request reprint Space-time clustering analyses of testicular cancer amongst 15-24-year-olds in Northern England
    R J Q McNally
    School of Clinical Medical Sciences Child Health, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
    Eur J Epidemiol 21:139-44. 2006
    ..The very limited finding of space-time clustering may provide tentative evidence for an environmental, or infectious component to aetiology. However, it may well be a chance finding. A larger study based on national data is required...
  17. ncbi request reprint Space-time clustering analyses of type 1 diabetes among 0- to 29-year-olds in Yorkshire, UK
    R J Q McNally
    School of Clinical Medical Sciences Child Health, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Diabetologia 49:900-4. 2006
    ..We tested for evidence of space-time clustering among children and young adults under 30 years of age using data from a population-based register in Yorkshire, UK...
  18. doi request reprint Seasonal variation in the patient diagnosis of primary biliary cirrhosis: further evidence for an environmental component to etiology
    Richard J Q McNally
    Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom
    Hepatology 54:2099-103. 2011
    ..Furthermore, there was evidence of a sinusoidal pattern with a June peak (P = 0.012). Conclusion: These highly novel results provide further evidence for the involvement of a seasonally varying environmental agent in the etiology of PBC...
  19. ncbi request reprint Evidence of an environmental contribution to the aetiology of cryptorchidism and hypospadias?
    N A Abdullah
    School of Clinical Medical Sciences Child Health, Sir James Spence Institute, Newcastle University, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK
    Eur J Epidemiol 22:615-20. 2007
    ..The aim was to determine if there is evidence of spatial heterogeneity in the prevalence of these conditions and to test the hypothesis that environmental factors may contribute to aetiology...
  20. pmc Survival from childhood cancer in northern England, 1968-2005
    N O Basta
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, England, UK
    Br J Cancer 105:1402-8. 2011
    ..Cancer is the second most common cause of death in children in the developed world. The study investigated patterns and trends in survival from childhood cancer in patients from northern England diagnosed 1968-2005...
  21. pmc Incidence and survival of childhood bone cancer in northern England and the West Midlands, 1981-2002
    R Eyre
    Institute of Health and Society, Newcastle University, Newcastle upon Tyne NE1 4LP, UK
    Br J Cancer 100:188-93. 2009
    ..98-1.05; P=0.35) over this time period. Reasons for failure to improve survival including potential delays in diagnosis, accrual to trials, adherence to therapy and lack of improvement in treatment strategies all need to be considered...
  22. ncbi request reprint Space-time clustering of childhood cancer in great Britain: a national study, 1969-1993
    Richard J Q McNally
    School of Clinical Medical Sciences Child Health and School of Population and Health Sciences, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle, United Kingdom
    Int J Cancer 118:2840-6. 2006
    ..Significant space-time clustering was also evident for soft tissue sarcomas (p = 0.03) and osteosarcomas (p = 0.02). Results support other evidence suggesting a role for infections in the aetiology of these particular diagnostic groups...
  23. doi request reprint Season of birth and diagnosis for childhood cancer in Northern England, 1968-2005
    Nermine O Basta
    Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
    Paediatr Perinat Epidemiol 24:309-18. 2010
    ..The results are consistent with a role for environmental factors in the aetiology of these diagnostic groups. Further studies are needed to examine putative candidate agents...
  24. ncbi request reprint Paternal occupational exposure to pesticides or herbicides as risk factors for cancer in children and young adults: a case-control study from the North of England
    Mark S Pearce
    School of Clinical Medical Sciences Child Health, University of Newcastle upon Tyne, England
    Arch Environ Occup Health 61:138-44. 2006
    ..Results do not support a role for preconception paternal occupational exposures to pesticides or herbicides in the etiology of childhood cancer...
  25. ncbi request reprint Paternal occupational exposure to electro-magnetic fields as a risk factor for cancer in children and young adults: a case-control study from the North of England
    Mark S Pearce
    Paediatric and Lifecourse Epidemiology Research Group, School of Clinical Medical Sciences Child Health, University of Newcastle upon Tyne, UK
    Pediatr Blood Cancer 49:280-6. 2007
    ..We investigated whether an association exists between paternal occupations at birth involving such exposures and cancer risk in offspring, using data from the Northern Region Young Persons' Malignant Disease Registry (NRYPMDR)...
  26. ncbi request reprint Examination of gender effect in birth weight and miscarriage associations with childhood cancer (United Kingdom)
    M Tevfik Dorak
    Paediatric and Lifecourse Epidemiology Research Group, Sir James Spence Institute, School of Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
    Cancer Causes Control 18:219-28. 2007
    ..Higher birth weight and maternal history of miscarriage has been associated with an increased risk of childhood leukemia. The possibility that this association may be sex-specific has not been explored in detail in previous studies...
  27. doi request reprint Geographical analysis of thyroid cancer in young people from northern England: evidence for a sustained excess in females in Cumbria
    Brooke L Magnanti
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, United Kingdom
    Eur J Cancer 45:1624-9. 2009
    ..8; 95% CI: 1.4-85.3). These findings may be consistent with sex-specific differences in susceptibility to an environmental exposure, such as fallout from the Chernobyl nuclear accident...
  28. pmc Birth prevalence of cryptorchidism and hypospadias in northern England, 1993-2000
    N A Abdullah
    Paediatric and Lifecourse Epidemiology Research Group, School of Clinical Medical Sciences Child Health, Newcastle University, Newcastle upon Tyne, UK
    Arch Dis Child 92:576-9. 2007
    ..To address this issue we investigated the birth prevalence of cryptorchidism and hypospadias in the northern region of England during the period 1993-2000...
  29. doi request reprint Space-time analysis of Down syndrome: results consistent with transient pre-disposing contagious agent
    Richard J Q McNally
    School of Clinical Medical Sciences Child Health, Newcastle University, Newcastle upon Tyne, UK
    Int J Epidemiol 37:1169-79. 2008
    ..We analysed for space-time clustering using high quality fully population-based data from a geographically defined region...
  30. pmc Socioeconomic variation in survival from childhood leukaemia in northern England, 1968-2010
    K Njoku
    Institute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    Br J Cancer 108:2339-45. 2013
    ....
  31. ncbi request reprint Geographical and ecological analyses of childhood Wilms' tumours and soft-tissue sarcomas in North West England
    Richard J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Manchester, UK
    Eur J Cancer 39:1586-93. 2003
    ..These results are consistent with a role for localised environmental exposures, in combination with lifestyle factors, in the aetiology of WT. For STS, there is some evidence for the involvement of environmental and/or lifestyle factors...
  32. ncbi request reprint Geographical and ecological analyses of childhood acute leukaemias and lymphomas in north-west England
    Richard J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Manchester, UK
    Br J Haematol 123:60-5. 2003
    ..The results for ALL and mixed cellularity HD support the involvement of environmental factors, such as infections, in disease aetiology...
  33. ncbi request reprint Further clues concerning the aetiology of childhood central nervous system tumours
    Richard J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Hospital Road, Manchester M27 4HA, United Kingdom
    Eur J Cancer 40:2766-72. 2004
    ..An example of such an agent is an infection that occurs in mini-epidemics...
  34. ncbi request reprint Geographical distribution of optic nerve hypoplasia and septo-optic dysplasia in Northwest England
    Leena Patel
    Academic Unit of Child Health, The University of Manchester, Booth Hall Children s Hospital, Manchester, United Kingdom
    J Pediatr 148:85-8. 2006
    ..To study the distribution of septo-optic dysplasia (SOD) and optic nerve hypoplasia (ONH) in the Greater Manchester and Lancashire (GM&L) region of Northwest England, and to analyze occurrence by location and over time...
  35. ncbi request reprint Re: Childhood leukemia incidence in Britain, 1974-2000: time trends and possible relation to influenza epidemics
    Richard J Q McNally
    J Natl Cancer Inst 98:1746; author reply 1746-7. 2006
  36. ncbi request reprint An infectious aetiology for childhood acute leukaemia: a review of the evidence
    Richard J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Manchester, UK
    Br J Haematol 127:243-63. 2004
    ....
  37. ncbi request reprint Space-time clustering of cryptorchidism and hypospadias
    Richard J Q McNally
    Epidemiology 18:183-4. 2007
  38. ncbi request reprint Re: "Childhood acute lymphoblastic leukemia and infections in the first year of life: a report from the United Kingdom childhood cancer study"
    M Tevfik Dorak
    Am J Epidemiol 166:364-5; author reply 365. 2007