M E McMurdo

..To determine the effectiveness of a behavior change intervention (BCI) with or without a pedometer in increasing physical activity in sedentary older women...

..To assess physical activity levels objectively using accelerometers in community dwelling over 65 s and to examine associations with health, social, environmental and psychological factors...

..To test the ease of use, reliability, responsiveness and construct validity of the Patient Generated Index, an individualised quality of life score, in older people attending a Medicine for Older People Day Hospital...

..The aim of this pilot study was to evaluate the feasibility of the use of pedometers plus a theory-based intervention to assist sedentary older women to accumulate increasing amounts of physical activity, mainly through walking...

..In this study we investigated the reasons why older people choose not to participate in a research project...

..cranberry juice is often given to older people in hospital to prevent urinary tract infection (UTI), although there is little evidence to support its use...

..Responsibility for injury prevention extends beyond general practice, but the primary care team must be prepared to play its part...

..To compare the effectiveness of cranberry extract with low-dose trimethoprim in the prevention of recurrent urinary tract infections (UTIs) in older women...

..To determine whether the oral nutritional supplementation of undernourished older people upon discharge from hospital improves muscle function and reduces disability...

..Increasing the participation of older people in research will improve the generalisability of research findings and inform best practice in the clinical management of the growing older population...

..A small number of fall prevention trials in cognitively intact community-dwelling older people have been effective. This study set out to examine the preventability of falls in older people living in institutional care...

..We sought to examine the effect of the angiotensin-converting-enzyme (ACE) inhibitor perindopril on physical function in elderly people with functional impairment who had no heart failure or left ventricular systolic dysfunction...

..This article will highlight some recent advances in knowledge. It will explore common myths that discourage the largely sedentary older population of the UK from changing their exercise habits...

..To assess the attitudes of consultant members of the British Geriatrics Society to elderly patients driving motor vehicles...

..Little information exists about diet in the management of heart failure...

..9%) than in the control group (7.2%). CONCLUSIONS: Oral nutritional supplementation was associated with a greater increase in handgrip strength than in non-supplemented controls and this observation merits further study...

..Six-minute walk distance and quality of life did not change between groups, but daily activity as measured by accelerometry increased in the exercise group relative to the control group...

..Exercise capacity and daily activity are key outcomes for older, frail heart failure patients. Little is known about the determinants of these outcomes in this patient group...

..We describe the literature to support our hypothesis that sarcopenia may be a potential therapeutic target for ACE inhibitors...

..Undernutrition is common in older people admitted to hospital with hip fracture. Oral supplementation with sip feeds may be provided but compliance is a major problem...

..To determine the predictive power of B-type natriuretic peptide (BNP) regarding death in older, functionally impaired patients with multiple comorbidity...

..To review all published observational studies reporting on all-cause mortality in patients with type 2 diabetes to determine the degree of increased mortality when diagnosed at an older age...

..We tested whether vitamin D supplementation of patients with heart failure and vitamin D insufficiency can improve physical function and quality of life...

..To realize these potential benefits, exercise programs that are suitable for older, frail people need to be established and tested in an older, frail, unselected population with comorbidities...

..Most studies of exercise training for heart failure have been conducted on relatively young patients with little comorbidity. Such programmes are unsuitable for the majority of older frail heart failure patients...

..Regular physical activity has been shown to have many health benefits. However, many older people are physically inactive...

..6 m/month in nonattenders; P=.03). Similar results were seen for other outcomes. Only a small proportion of the variance in change of any of the outcomes was explained by differences in baseline variables...

..The Patient Generated Index is a recently introduced tool that allows individualised assessment of quality of life...

..The impact of exercise programmes for heart failure on those close to the patient is largely unknown. We examined the effect of a hospital and home-based exercise intervention on burden, anxiety and depression of informal caregivers...

..This has implications for the most effective targeting of evidence based treatment...

..B-type natriuretic peptide increases progressively as the number of different cardiac abnormalities increases and this may explain why B-type natriuretic peptide is of such prognostic value in older patients...

..00-6.38). CONCLUSIONS: Because exercise was associated with a modest improvement in depressive symptoms at 10 weeks, older people with poorly responsive depressive disorder should be encouraged to attend group exercise activities...

..Other differences in the intestinal ecosystem in elderly subjects were observed, with alterations in the dominant clostridial species in combination with greater numbers of facultative anaerobes...

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..Combined vitamin K with vitamin D plus calcium was associated with a modest but significant increase in BMC at the ultradistal radius but not at other sites in the hip or radius...

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..01 [0.93-1.10]). CONCLUSIONS: Men diagnosed with type 2 diabetes over the age of 65 years have no excess mortality compared with their nondiabetic counterparts, a finding that was not replicated for women...

..This paper serves to provide simple and digestible guidance on the key components of a comprehensive falls service as derived from the existing evidence base...

..To identify clinical risk assessment tools or individual clinical risk factors predictive of falls, with the ultimate aim of informing the design of effective fall prevention strategies...

..This study aimed to extend previous work using the D-C model of job strain to predict caregiver burden and satisfaction in the informal caregivers of patients with heart failure...