Gordon T McInnes

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. ncbi request reprint Lowering blood pressure for cardiovascular risk reduction
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Gardiner Institute, Western Infirmary, University of Glasgow, Glasgow, UK
    J Hypertens Suppl 23:S3-8. 2005
  2. doi request reprint Blood pressure response to patterns of weather fluctuations and effect on mortality
    Louise Aubinière-Robb
    BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom
    Hypertension 62:190-6. 2013
  3. doi request reprint Acetaminophen use and change in blood pressure in a hypertensive population
    Jesse Dawson
    Institute of Cardiovascular and Medical Sciences, School of Medicine, West of Scotland Cancer Surveillance Unit, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    J Hypertens 31:1485-90; discussion 1490. 2013
  4. doi request reprint Resting heart rate pattern during follow-up and mortality in hypertensive patients
    Laura Paul
    British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Hypertension 55:567-74. 2010
  5. doi request reprint Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults
    Laura Paul
    British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom
    Hypertension 60:631-8. 2012
  6. ncbi request reprint How important is optimal blood pressure control?
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kingdom
    Clin Ther 26:A3-11. 2004
  7. ncbi request reprint The expanding role of angiotensin receptor blockers in the management of the elderly hypertensive
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Gardiner Institute, Western Infirmary, Glasgow, University of Glasgow, UK
    Curr Med Res Opin 19:452-5. 2003
  8. ncbi request reprint Never mind the quality, feel the width--ALLHAT revisited
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Western Infirmary, University of Glasgow, Glasgow G11 6NT, UK
    Blood Press 13:330-4. 2004
  9. doi request reprint Risks of socioeconomic deprivation on mortality in hypertensive patients
    Luisa Stewart
    University of Glasgow, Faculty of Medicine, Division of Community Based Sciences, Glasgow, Scotland, UK
    J Hypertens 27:730-5. 2009
  10. doi request reprint Drug treatment of prehypertension: Not now, not ever?
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, Western Infirmary, University of Glasgow, Glasgow G11 6NT, UK
    Blood Press 18:304-7. 2009

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Lowering blood pressure for cardiovascular risk reduction
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Gardiner Institute, Western Infirmary, University of Glasgow, Glasgow, UK
    J Hypertens Suppl 23:S3-8. 2005
    ..Prescribing habits must change, and soon, if we are to avoid an upsurge in cardiovascular complications...
  2. doi request reprint Blood pressure response to patterns of weather fluctuations and effect on mortality
    Louise Aubinière-Robb
    BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom
    Hypertension 62:190-6. 2013
    ..Knowing a patient's blood pressure response to weather can help reduce unnecessary antihypertensive treatment modification, which may in turn increase blood pressure variability and, thus, risk...
  3. doi request reprint Acetaminophen use and change in blood pressure in a hypertensive population
    Jesse Dawson
    Institute of Cardiovascular and Medical Sciences, School of Medicine, West of Scotland Cancer Surveillance Unit, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    J Hypertens 31:1485-90; discussion 1490. 2013
    ..We investigated the association between acetaminophen use and BP in a large cohort of patients with hypertension using verified prescription data...
  4. doi request reprint Resting heart rate pattern during follow-up and mortality in hypertensive patients
    Laura Paul
    British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Hypertension 55:567-74. 2010
    ..Change in HR achieved during follow-up of hypertensive patients is a better predictor of risk than baseline or final HR. After correction for rate-limiting therapy, HR remained a significant independent risk factor...
  5. doi request reprint Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults
    Laura Paul
    British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom
    Hypertension 60:631-8. 2012
    ..Hypertensive patients with hematocrit levels outside of the sex-specific reference ranges identified in this study should be targeted for more aggressive blood pressure and cardiovascular risk reduction treatment...
  6. ncbi request reprint How important is optimal blood pressure control?
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kingdom
    Clin Ther 26:A3-11. 2004
    ..Recent evidence has emphasized the importance of optimal blood pressure control, particularly in patients with high cardiovascular risk, such as those with type 2 diabetes mellitus...
  7. ncbi request reprint The expanding role of angiotensin receptor blockers in the management of the elderly hypertensive
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Gardiner Institute, Western Infirmary, Glasgow, University of Glasgow, UK
    Curr Med Res Opin 19:452-5. 2003
    ..Thus, ARBs have a bright future in the management of hypertension and in the treatment of stroke and cognitive decline in the elderly...
  8. ncbi request reprint Never mind the quality, feel the width--ALLHAT revisited
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Western Infirmary, University of Glasgow, Glasgow G11 6NT, UK
    Blood Press 13:330-4. 2004
  9. doi request reprint Risks of socioeconomic deprivation on mortality in hypertensive patients
    Luisa Stewart
    University of Glasgow, Faculty of Medicine, Division of Community Based Sciences, Glasgow, Scotland, UK
    J Hypertens 27:730-5. 2009
    ....
  10. doi request reprint Drug treatment of prehypertension: Not now, not ever?
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, Western Infirmary, University of Glasgow, Glasgow G11 6NT, UK
    Blood Press 18:304-7. 2009
    ..Any changes in recommendations should await adequately powered outcome studies, which provide solid evidence of the magnitude of absolute risk reduction in treating prehyper-tension and assessment of the cost-effectiveness...
  11. pmc The unintended consequences of clinical trials regulations
    Alex D McMahon
    Dental School, Faculty of Medicine, University of Glasgow, Glasgow, Scotland
    PLoS Med 3:e1000131. 2009
    ..Alex McMahon and colleagues critique the International Conference on Harmonisation (ICH) guidance on good clinical practice (GCP), arguing that it is having a disastrous effect on noncommerical randomized clinical trials in Europe...
  12. doi request reprint Noninvasive cardiac event monitoring to detect atrial fibrillation after ischemic stroke: a randomized, controlled trial
    Peter Higgins
    From the College of Medical, Veterinary and Life Sciences, Institute of Cardiovascular and Medical Sciences P H, P W M, J D, G T M, P L, K R L, Gardiner Institute, Western Infirmary P H, J D, G T M, K R L, Glasgow Royal Infirmary P W M, P L, University of Glasgow, Glasgow, United Kingdom
    Stroke 44:2525-31. 2013
    ..We hypothesized that 7 days of noninvasive cardiac-event monitoring early after stroke would accelerate detection of AF and thus uptake of effective therapy...
  13. ncbi request reprint The differences between ACE inhibitor-treated and calcium channel blocker-treated hypertensive patients
    Gordon T McInnes
    University of Glasgow, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, United Kingdom
    J Clin Hypertens (Greenwich) 5:337-44. 2003
    ....
  14. doi request reprint Long-term outcome following attendance at a transient ischemic attack clinic
    Alan C Cameron
    Division of Cardiovascular and Medical Sciences, Gardiner Institute, Faculty of Medicine, University of Glasgow, Glasgow, UK
    Int J Stroke 6:306-11. 2011
    ..The long-term outcomes in this group are not well described. We evaluated these in a cohort referred to a transient ischemic attack clinic with a suspected transient ischemic attack...
  15. ncbi request reprint Introduction: the role of angiotensin receptor blockers in preventing stroke and cognitive decline
    Gordon T McInnes
    Division of Cardiovascular and Medical Sciences, Gardiner Institute, Western Infirmary, Glasgow, University of Glasgow, UK
    Curr Med Res Opin 19:437. 2003
  16. ncbi request reprint Special management needs of the elderly hypertensive patient
    Henry L Elliott
    University Department of Medicine and Therapeutics, Western Infirmary, Glasgow, G11 6NT, UK
    J Renin Angiotensin Aldosterone Syst 3:S25-31. 2002
  17. ncbi request reprint Drug Insight: eplerenone, a mineralocorticoid-receptor antagonist
    Frances McManus
    University of Glasgow, Glasgow, UK
    Nat Clin Pract Endocrinol Metab 4:44-52. 2008
    ..In addition we detail the effects of eplerenone in a number of clinical situations and outline its potential future applications...
  18. ncbi request reprint What is the true place of blood pressure in cardiovascular risk management?
    Gordon T McInnes
    University of Glasgow, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, UK
    J Hypertens 25:925-8. 2007
  19. ncbi request reprint Clinical trials and tribulations
    Gordon T McInnes
    University of Glasgow, Department of Medicine and Therapeutics, Western Infirmary, Glasgow, UK
    Clin Exp Pharmacol Physiol 29:951-5. 2002
    ..Clinical pharmacologists have a critical role in design and evaluation of pharmacoepidemiology studies...
  20. ncbi request reprint Effect of area-based deprivation on the severity, subtype, and outcome of ischemic stroke
    Stella Aslanyan
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Gardiner Institute, Western Infirmary, Glasgow G11 6NT, UK
    Stroke 34:2623-8. 2003
    ..In the United Kingdom, area-based deprivation measures are available routinely through links with postal codes. We hypothesized that deprivation is associated with ischemic stroke risk factors, severity, subtype, and outcome...
  21. doi request reprint Progressive effects of valsartan compared with amlodipine in prevention of diabetes according to categories of diabetogenic risk in hypertensive patients: the VALUE trial
    Sverre E Kjeldsen
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
    Blood Press 17:170-7. 2008
    ..We conclude that valsartan compared with amlodipine reduces the risk of developing diabetes mellitus, particularly in hypertensive patients with the highest susceptibility for development of diabetes...
  22. doi request reprint The Anglo-Scandinavian Cardiac Outcomes Trial: blood pressure-lowering limb: effects in patients with type II diabetes
    Jan Ostergren
    Department of Medicine, Karolinska University Hospital Solna, Stockholm, Sweden
    J Hypertens 26:2103-11. 2008
    ....
  23. ncbi request reprint The role of olmesartan medoxomil in the management of hypertension
    Thomas Unger
    Center for Cardiovascular Research, Institute of Pharmacology and Toxicology, Charite University Medicine Berlin, Berlin, Germany
    Drugs 64:2731-9. 2004
    ....
  24. ncbi request reprint Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial
    Michael A Weber
    State University of New York, Brooklyn, NY, USA
    Lancet 363:2049-51. 2004
    ....
  25. ncbi request reprint Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial
    Stevo Julius
    University of Michigan, Ann Arbor, USA
    Lancet 363:2022-31. 2004
    ....
  26. ncbi request reprint Effects of valsartan compared to amlodipine on preventing type 2 diabetes in high-risk hypertensive patients: the VALUE trial
    Sverre E Kjeldsen
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA
    J Hypertens 24:1405-12. 2006
    ..Type 2 diabetes is emerging as a major health problem, which tends to cluster with hypertension in individuals at high risk of cardiovascular disease...
  27. pmc British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester
    BMJ 328:634-40. 2004
  28. ncbi request reprint Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomis
    Peter S Sever
    Imperial College, London, UK
    Lancet 361:1149-58. 2003
    ..No study, however, has assessed benefits of cholesterol lowering in the primary prevention of coronary heart disease (CHD) in hypertensive patients who are not conventionally deemed dyslipidaemic...
  29. ncbi request reprint Size isn't everything--ALLHAT in perspective
    Gordon T McInnes
    J Hypertens 21:459-61. 2003
  30. ncbi request reprint Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomis
    Peter S Sever
    Imperial College, London, UK
    Drugs 64:43-60. 2004
    ..No study, however, has assessed benefits of cholesterol lowering in the primary prevention of coronary heart disease (CHD) in hypertensive patients who are not conventionally deemed dyslipidaemic...
  31. ncbi request reprint Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-B
    Bjorn Dahlof
    Department of Medicine, Sahlgrenska University Hospital Ostra, SE 416 85 Goteborg, Sweden
    Lancet 366:895-906. 2005
    ..Our aim, therefore, was to compare the effect on non-fatal myocardial infarction and fatal CHD of combinations of atenolol with a thiazide versus amlodipine with perindopril...
  32. ncbi request reprint Reduction in cardiovascular events with atorvastatin in 2,532 patients with type 2 diabetes: Anglo-Scandinavian Cardiac Outcomes Trial--lipid-lowering arm (ASCOT-LLA)
    Peter S Sever
    International Centre for Circulatory Health, NHLI, Faculty of Medicine, Imperial College London, St Mary s Campus, 59 N Wharf Road, London W2 1PG, U K
    Diabetes Care 28:1151-7. 2005
    ..This study aims to establish the benefits of lowering cholesterol in diabetic patients with well-controlled hypertension and average/below-average cholesterol concentrations, but without established coronary disease...
  33. ncbi request reprint The relationships between initial blood pressure and the response to different antihypertensive agents
    Peter A Meredith
    J Hypertens 25:2513-4; author reply 2514. 2007
  34. ncbi request reprint Prediction of cardiovascular outcome by estimated glomerular filtration rate and estimated creatinine clearance in the high-risk hypertension population of the VALUE trial
    Luis M Ruilope
    Hypertension Unit, Hospital 12 de Octubre, Madrid, Spain
    J Hypertens 25:1473-9. 2007
    ..Reduced renal function is predictive of poor cardiovascular outcomes but the predictive value of different measures of renal function is uncertain...
  35. ncbi request reprint Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA)
    Neil R Poulter
    Imperial College London, London, UK
    Lancet 366:907-13. 2005
    ..86 and 0.77, respectively). Our aim was to assess to what extent these differences were due to significant differences in blood pressures and in other variables noted after randomisation...
  36. ncbi request reprint The Valsartan Antihypertensive Long-Term Use Evaluation (VALUE) trial: outcomes in patients receiving monotherapy
    Stevo Julius
    University of Michigan, Department of Internal Medicine, Division of Cardiovascular Medicine, 24 Frank Lloyd Wright Dr, PO Box 322, Lobby M, Ann Arbor, MI 48106, USA
    Hypertension 48:385-91. 2006
    ..Moreover, these findings support the feasibility of comparative prospective trials in lower-risk hypertensive patients...
  37. ncbi request reprint Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: An analysis of findings from the VALUE trial
    Alberto Zanchetti
    aCentro Interuniversitario di Fisiologia Clinica e Ipertensione, University of Milan, Istituto Auxologico Italiano and Ospedale Maggiore, Milan, Italy
    J Hypertens 24:2163-8. 2006
    ..Stroke incidence was non-significantly, and myocardial infarction was significantly lower in the amlodipine-based regimen, whereas cardiac failure was non-significantly lower on valsartan...
  38. pmc Influence of a single dose of 20 mg tadalafil, a phosphodiesterase 5 inhibitor, on ambulatory blood pressure in subjects with hypertension
    Dean Patterson
    Department of Medicine, Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, Dundee, UK
    Br J Clin Pharmacol 62:280-7. 2006
    ..To test the non-inferiority of a single dose of tadalafil 20 mg compared with placebo with respect to 26-h mean ambulatory systolic and diastolic blood pressure in treated and untreated hypertensive subjects...
  39. doi request reprint Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial
    Roland E Schmieder
    Department of Nephrology and Hypertension, University Erlangen Nuremberg, Erlangen, Germany
    J Hypertens 26:403-11. 2008
    ..Therefore, in the Valsartan Antihypertensive Long-term Use Evaluation (VALUE) a prespecified objective was to compare the effects of valsartan and amlodipine on new-onset AF...
  40. pmc Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study
    Hari K Parthasarathy
    Division of Medicine and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
    BMC Cardiovasc Disord 7:14. 2007
    ....
  41. ncbi request reprint Antioxidants and hypertension: another false dawn?
    Gordon T McInnes
    J Hypertens 23:1963-6. 2005