Research Topics
Genomes and Genes | R A McIlhinneySummaryAffiliation: University of Oxford Country: UK Publications
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Publications
Characterization of human and rat brain myristoyl-CoA:protein N-myristoyltransferase: evidence for an alternative splice variant of the enzymeR A McIlhinney
Medical Research Council Anatomical Neuropharmacology Unit, Mansfield Road, Oxford OX1 3TH, UK
Biochem J 333:491-5. 1998..Our results provide evidence that this enzyme exists in different forms resulting from alternative splicing of the mRNA...
Assembly of N-methyl-D-aspartate (NMDA) receptorsR A J McIlhinney
MRC Anatomical Neuropharmacology Unit, Mansfield Road, Oxford OX1 3TH, UK
Biochem Soc Trans 31:865-8. 2003....
Identification of molecular determinants that are important in the assembly of N-methyl-D-aspartate receptorsE Meddows
Medical Research Council Anatomical Neuropharmacology Unit, Mansfield Road, Oxford OX1 3TH
J Biol Chem 276:18795-803. 2001..Together these results suggest the residues N-terminal of residue 380 are important for the association of NR2A with NR1a and that the complete N-terminal domain of the NR1a subunit is required for oligomerization with NR2A...
Mouse brain and muscle tissues constitutively express high levels of Homer proteinsM M Soloviev
Medical Research Council, Anatomical Neuropharmacology Unit, Mansfield Road, Oxford, UK
Eur J Biochem 267:634-9. 2000..We have shown that the molecular profile of expression of Homer-1, -2 and -3 mRNAs in muscle containing tissues resembles that obtained for mammalian brain...
The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellumA Becher
Medical Research Council Anatomical Neuropharmacology Unit, Mansfield Road, Oxford, UK
J Neurochem 79:787-95. 2001..These properties are all consistent with an association of the GABA(B) receptor with lipid raft microdomains...
Identification, cloning and analysis of expression of a new alternatively spliced form of the metabotropic glutamate receptor mGluR1 mRNA1M M Soloviev
Medical Research Council, Anatomical Neuropharmacology Unit, Mansfield Road, Oxford OX1 3TH, UK
Biochim Biophys Acta 1446:161-6. 1999..mGluR1f differs from the mGluR1a mRNA by deletion of a 35-bp fragment of the mGluR1a/alpha coding sequence and insertion of an 85-bp fragment, found only in mGluR1b/beta mRNA...
Characterization of the dimerization of metabotropic glutamate receptors using an N-terminal truncation of mGluR1alphaM J Robbins
Medical Research Council Anatomical Neuropharmacology Unit, Oxford, England, UK
J Neurochem 72:2539-47. 1999..These results show that although the N-terminal domain of mGluR1alpha is sufficient for dimer formation, other domains in the molecule must regulate the process...
Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicingM M Soloviev
Medical Research Council Anatomical Neuropharmacology Unit, Mansfield Road, Oxford, OX1 3TH, UK
J Mol Biol 295:1185-200. 2000..The existence of the long and the short variants of each of the Homer-1, Homer-2 and Homer-3 proteins reflects the fundamental principles of Homer functions...
Identification of a novel region of the GABA(B2) C-terminus that regulates surface expression and neuronal targeting of the GABA(B) receptorA M Pooler
Medical Research Council, Anatomical Neuropharmacology Unit, Mansfield Road, Oxford OX13TH, UK
Eur J Neurosci 29:869-78. 2009..Taken together, these data show that the region of the GABA(B2) C-terminus between residues 841 and 862 is important for regulating forward trafficking and neuronal targeting of the GABA(B) receptor...
