Genomes and Genes
K A McAulay
Affiliation: University of Edinburgh
- Cytolytic mechanisms and T-cell receptor Vbeta usage by ex vivo generated Epstein-Barr virus-specific cytotoxic T lymphocytesVictoria J Vanhoutte
Clinical and Molecular Virology, University of Edinburgh, Summerhall, Edinburgh, UK
Immunology 127:577-86. 2009..001). This difference was not observed with Fas ligand or perforin expression. Our results provide insight into the basic characteristics of ex-vivo-generated CTL...
- HLA class I polymorphisms are associated with development of infectious mononucleosis upon primary EBV infectionKaren A McAulay
Clinical and Basic Virology Laboratory, School of Biomedical and Clinical Laboratory Sciences, University of Edinburgh, Summerhall, Edinburgh, United Kingdom
J Clin Invest 117:3042-8. 2007....
- Epitope specificity and clonality of EBV-specific CTLs used to treat posttransplant lymphoproliferative diseaseKaren A McAulay
Clinical and Basic Virology Laboratory, School of Biomedical Sciences, University of Edinburgh, Summerhall, Edinburgh, UK
J Immunol 182:3892-901. 2009..These observations should be considered when designing and implementing CTL therapies...
- Tumour necrosis factor gene polymorphism: a predictive factor for the development of post-transplant lymphoproliferative diseaseK A McAulay
Clinical and Basic Virology Laboratory, School of Biomedical Sciences, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK
Br J Cancer 101:1019-27. 2009..We undertook investigation of polymorphic alleles within cytokine genes in PTLD and non-PTLD transplant cohorts to determine risk factors for disease...
- Regulatory T cell activity in primary and persistent Epstein-Barr virus infectionP J Wingate
Clinical and Molecular Virology, Summerhall, University of Edinburgh, Edinburgh, United Kingdom
J Med Virol 81:870-7. 2009..03). It is possible that T(reg) are important in controlling primary EBV infection to a subclinical level in most cases and that infectious mononucleosis represents a failure of this protective mechanism...
- Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusionPhilip N Newsome
Department of Hepatology, Chancellor s Building, University of Edinburgh, Edinburgh EH16 4SB, Scotland, UK
Gastroenterology 124:1891-900. 2003..We also wanted to test whether such differentiated cells were the result of cellular fusion or true stem cell transdifferentiation...
- Infectious mononucleosis in university students in the United kingdom: evaluation of the clinical features and consequences of the diseaseKaren F Macsween
Department of Clinical and Molecular Virology, University of Edinburgh, Summerhall, United Kingdom
Clin Infect Dis 50:699-706. 2010..Infectious mononucleosis (IM) is common among university students. We undertook to analyze the clinical features and sequelae of the disease in a cohort of students at Edinburgh University...