R Hamish McAllister-Williams

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi request reprint NICE guidelines for the management of depression
    R Hamish McAllister-Williams
    Br J Hosp Med (Lond) 67:60-1. 2006
  2. pmc NICE guidelines on antidepressants
    R Hamish McAllister-Williams
    Br J Gen Pract 56:798-800. 2006
  3. ncbi request reprint Corticosterone selectively attenuates 8-OH-DPAT-mediated hypothermia in mice
    R H McAllister-Williams
    Department of Psyciatry, School of Neuscience and Psychiatry, University of Newcastle, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Int J Neuropsychopharmacol 4:1-8. 2001
  4. ncbi request reprint Bipolar disorder ignored by the Mental Health National Service framework but not forgotten by the British Association for Psychopharmacology
    R H McAllister-Williams
    Psychobiology Research Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Psychopharmacol 17:7-10. 2003
  5. ncbi request reprint Repeated cortisol administration attenuates the EEG response to buspirone in healthy volunteers: evidence for desensitization of the 5-HT1A autoreceptor
    R Hamish McAllister-Williams
    Psychobiology Research Group, School of Neuroscience and Psychiatry, University of Newcastle, Newcastle upon Tyne, UK
    J Psychopharmacol 21:826-32. 2007
  6. ncbi request reprint Relapse prevention in bipolar disorder: a critical review of current guidelines
    R Hamish McAllister-Williams
    School of Neuroscience and Psychiatry, University of Newcastle, Newcastle upon Tyne, UK
    J Psychopharmacol 20:12-6. 2006
  7. ncbi request reprint EEG effects of buspirone and pindolol: a method of examining 5-HT1A receptor function in humans
    R H McAllister-Williams
    Psychobiology Research Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle, NE1 4LP, Newcastle upon Tyne, UK
    Psychopharmacology (Berl) 166:284-93. 2003
  8. doi request reprint Birth weight of infants after maternal exposure to typical and atypical antipsychotics: prospective comparison study
    James J Newham
    University of Newcastle, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Psychiatry 192:333-7. 2008
  9. ncbi request reprint Do antidepressants work? A commentary on "Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration" by Kirsch et al
    R H McAllister-Williams
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE1 4LP, UK
    Evid Based Ment Health 11:66-8. 2008
  10. ncbi request reprint Effects of tryptophan depletion on brain potential correlates of episodic memory retrieval
    R H McAllister-Williams
    Department of Psychiatry, University of Newcastle, Newcastle upon Tyne NE1 4LP, UK
    Psychopharmacology (Berl) 160:434-42. 2002

Collaborators

Detail Information

Publications30

  1. ncbi request reprint NICE guidelines for the management of depression
    R Hamish McAllister-Williams
    Br J Hosp Med (Lond) 67:60-1. 2006
  2. pmc NICE guidelines on antidepressants
    R Hamish McAllister-Williams
    Br J Gen Pract 56:798-800. 2006
  3. ncbi request reprint Corticosterone selectively attenuates 8-OH-DPAT-mediated hypothermia in mice
    R H McAllister-Williams
    Department of Psyciatry, School of Neuscience and Psychiatry, University of Newcastle, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Int J Neuropsychopharmacol 4:1-8. 2001
    ..This demonstrates a serotonergic-nicotinic interaction in the generation of hypothermia in mice and is consistent with corticosterone selectively attenuating somatodendritic 5-HT1A receptor function...
  4. ncbi request reprint Bipolar disorder ignored by the Mental Health National Service framework but not forgotten by the British Association for Psychopharmacology
    R H McAllister-Williams
    Psychobiology Research Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Psychopharmacol 17:7-10. 2003
    ..Local Implementation Teams would be well advised to take note of the recently published British Association for Psychopharmacology guidelines for the management of BD...
  5. ncbi request reprint Repeated cortisol administration attenuates the EEG response to buspirone in healthy volunteers: evidence for desensitization of the 5-HT1A autoreceptor
    R Hamish McAllister-Williams
    Psychobiology Research Group, School of Neuroscience and Psychiatry, University of Newcastle, Newcastle upon Tyne, UK
    J Psychopharmacol 21:826-32. 2007
    ..However, following treatment with cortisol, the effect of buspirone was significantly attenuated. This is consistent with corticosteroids having a similar effect on somatodendritic 5-HT(1A) autoreceptors in man as seen in rodents...
  6. ncbi request reprint Relapse prevention in bipolar disorder: a critical review of current guidelines
    R Hamish McAllister-Williams
    School of Neuroscience and Psychiatry, University of Newcastle, Newcastle upon Tyne, UK
    J Psychopharmacol 20:12-6. 2006
    ..All other treatment options currently have an extremely limited evidence base and do not feature consistently in the published guidelines...
  7. ncbi request reprint EEG effects of buspirone and pindolol: a method of examining 5-HT1A receptor function in humans
    R H McAllister-Williams
    Psychobiology Research Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle, NE1 4LP, Newcastle upon Tyne, UK
    Psychopharmacology (Berl) 166:284-93. 2003
    ..Animal research suggests that pindolol is an agonist at these receptors but an antagonist at postsynaptic 5-HT(1A) receptors...
  8. doi request reprint Birth weight of infants after maternal exposure to typical and atypical antipsychotics: prospective comparison study
    James J Newham
    University of Newcastle, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Psychiatry 192:333-7. 2008
    ..The effects of in utero exposure to atypical antipsychotics on infant birth weight are unknown...
  9. ncbi request reprint Do antidepressants work? A commentary on "Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration" by Kirsch et al
    R H McAllister-Williams
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE1 4LP, UK
    Evid Based Ment Health 11:66-8. 2008
  10. ncbi request reprint Effects of tryptophan depletion on brain potential correlates of episodic memory retrieval
    R H McAllister-Williams
    Department of Psychiatry, University of Newcastle, Newcastle upon Tyne NE1 4LP, UK
    Psychopharmacology (Berl) 160:434-42. 2002
    ..Neuropsychological impairments in depressive illness may be secondary to proposed serotonergic abnormalities. Acute tryptophan depletion (ATD) in healthy subjects impairs episodic memory, but the mechanism of this is unclear...
  11. ncbi request reprint Effects of repeated cortisol administration on brain potential correlates of episodic memory retrieval
    R H McAllister-Williams
    Department of Psychiatry, University of Newcastle, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    Psychopharmacology (Berl) 160:74-83. 2002
    ..Neuropsychological impairments in depressive illness may be secondary to hypercortisolaemia. Cortisol administration to healthy subjects impairs episodic memory, though how this is mediated is unknown...
  12. doi request reprint Effects of cortisol on the laterality of the neural correlates of episodic memory
    Hamid A Alhaj
    Psychobiology Research Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    J Psychiatr Res 42:971-81. 2008
    ..The results support the hypothesis of causal effects of cortisol on the laterality of cortical activity occurring during an episodic memory task...
  13. ncbi request reprint A study of the neural correlates of episodic memory and HPA axis status in drug-free depressed patients and healthy controls
    Hamid A Alhaj
    Psychobiology Research Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, United Kingdom
    J Psychiatr Res 41:295-304. 2007
    ..These unique findings demonstrate that while the laterality of the neural correlates of episodic memory is sensitive to cortisol, it is not altered by the non-specific laterality effects seen in depression...
  14. pmc Effects of acute tryptophan depletion on executive function in healthy male volunteers
    Peter Gallagher
    Stanley Research Centre, School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, NE1 4LP, UK
    BMC Psychiatry 3:10. 2003
    ....
  15. ncbi request reprint Effects of DHEA administration on episodic memory, cortisol and mood in healthy young men: a double-blind, placebo-controlled study
    Hamid A Alhaj
    Psychobiology Research Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Psychopharmacology (Berl) 188:541-51. 2006
    ..Dehydroepiandrosterone (DHEA) has been reported to enhance cognition in rodents, although there are inconsistent findings in humans...
  16. doi request reprint Effects of intrinsic and extrinsic motivation on attention and memory
    Lucy J Robinson
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE4 5PL, UK
    Acta Psychol (Amst) 141:243-9. 2012
    ..The effects of motivational factors should not be overlooked when interpreting absolute levels of performance in neuropsychological processes...
  17. ncbi request reprint Assessing cortisol and dehydroepiandrosterone (DHEA) in saliva: effects of collection method
    Peter Gallagher
    School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    J Psychopharmacol 20:643-9. 2006
    ..2;R(2) 0.04). It is crucial that future studies are aware of these issues and are cognizant of the effects of the method of collection when examining steroid levels in saliva...
  18. ncbi request reprint Effects of a single dose of cortisol on the neural correlates of episodic memory and error processing in healthy volunteers
    F C Hsu
    Psychobiology Research Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Psychopharmacology (Berl) 167:431-42. 2003
    ..It is unclear whether such ERP effects are specific to episodic memory, or whether repeated cortisol administration is required...
  19. ncbi request reprint Managing the aftermath of mania - Newcastle, 2 September 2005: Consensus Meeting Statement
    Allan H Young
    University of Newcastle, Newcastle upon Tyne, UK
    J Psychopharmacol 20:51-4. 2006
  20. ncbi request reprint Antidepressants: will new mechanisms of action improve poor outcomes?
    Lena Palaniyappan
    Institute of Neuroscience, Newcastle University, Royal Victoria Infirmary, Newcastle upon Tyne
    Br J Hosp Med (Lond) 69:88-90. 2008
    ..Despite the numerous treatment approaches, poor response combined with the burden of residual symptoms negatively affects the overall outcome. Novel pharmacological approaches could help to address this issue...
  21. ncbi request reprint Corticosterone modulation of somatodendritic 5-HT1A receptor function in mice
    Mei See Man
    Psychobiology Research Group, School of Neuroscience and Psychiatry, University of Newcastle, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Psychopharmacol 16:245-52. 2002
    ..In addition, the degree of attenuation depends on CORT concentrations at the time of testing. These findings may have implications regarding mechanisms of adaptation to stress...
  22. doi request reprint Effect of low-dose acute tryptophan depletion on the specificity of autobiographical memory in healthy subjects with a family history of depression
    Hamid A Alhaj
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Psychopharmacology (Berl) 222:285-92. 2012
    ..Low-dose acute tryptophan depletion (LD-ATD), while having no effect on mood, has been shown to reduce specificity of autobiographical memory in patients who have recovered from a depressive episode...
  23. ncbi request reprint Maximizing treatment outcomes in the depressed patient
    Ciaran Corcoran
    Clinical Psychopharmacology and Honorary Consultant Psychiatrist, School of Neurology, Neurobiology and Psychiatry, Royal Victoria Infirmary, Newcastle upon Tyne
    Br J Hosp Med (Lond) 68:373-5. 2007
    ..However, outcomes are often far from ideal with patients left with residual symptoms of depression. These are associated with poor social functioning and an increased risk of relapse...
  24. doi request reprint The use of the EEG in measuring therapeutic drug action: focus on depression and antidepressants
    Hamid Alhaj
    Institute of Neuroscience, Newcastle University, Newcastle, UK
    J Psychopharmacol 25:1175-91. 2011
    ..Both of these uses of the EEG are illustrated in reference to the study of mood disorders and in particular depression and its treatment with antidepressants...
  25. ncbi request reprint Rapid tranquillisation: time for a reappraisal of options for parenteral therapy
    R Hamish McAllister-Williams
    Department of Psychiatry, University of Newcastle, Newcastle upon Tyne, UK
    Br J Psychiatry 180:485-9. 2002
    ..However, there has been recent concern over cardiotoxicity and sudden death associated with some antipsychotic medication and droperidol has now been withdrawn...
  26. ncbi request reprint Lack of effect of tryptophan depletion on the loudness dependency of auditory event related potentials in healthy volunteers
    A E Massey
    Department of Psychiatry, University of Newcastle, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    Biol Psychol 65:137-45. 2004
    ..No significant effect of tryptophan depletion was found on ASF-slope. These negative findings cast further doubt on the hypothesis that the ASF-slope is an indicator of central 5-HT function...
  27. ncbi request reprint Misinterpretation of randomized trial evidence: do antidepressants work?
    R Hamish McAllister-Williams
    Br J Hosp Med (Lond) 69:246-7. 2008
  28. ncbi request reprint Prescribing of venlafaxine and dosulepin in primary care
    R Hamish McAllister-Williams
    J Psychopharmacol 20:868. 2006
  29. pmc Graduate mental health worker case management of depression in UK primary care: a pilot study
    Lindsay McMahon
    Northumberland, Tyne and Wear NHS Trust, Sunderland
    Br J Gen Pract 57:880-5. 2007
    ....
  30. ncbi request reprint Be vigilant for symptoms of bipolar disorder
    Ciaran Corcoran
    Regional Affective Disorders Service, Northumberland, Tyne and Wear NHS Trust
    Practitioner 250:33-5, 38, 40. 2006