Sharon A Matthews

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. pmc Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues
    Sharon A Matthews
    Medical Research Institute, Ninewells Hospital and Medical School University of Dundee, Dundee, UK
    Eur J Immunol 42:1316-26. 2012
  2. pmc Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes
    Sharon A Matthews
    Division of Cell Biology and Immunology, School of Life Sciences, University of Dundee, Scotland, United Kingdom
    Mol Cell Biol 26:1569-77. 2006
  3. pmc Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells
    Sharon A Matthews
    Ninewells Hospital, University of Dundee, Scotland, UK
    Biochem J 432:153-63. 2010
  4. pmc Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells
    Maria N Navarro
    The College of Life Sciences, Division of Cell Signalling and Immunology, The University of Dundee, Scotland, UK
    Biochem J 442:649-59. 2012
  5. pmc Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFkappaB activity in vertebrate B-cells
    Ping Liu
    Division of Cell Biology and Immunology, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK
    FEBS Lett 581:1377-82. 2007
  6. pmc New insights into the regulation and function of serine/threonine kinases in T lymphocytes
    Sharon A Matthews
    Division of Medical Sciences, Centre for Oncology and Molecular Medicine, Ninewell s Hospital and Medical School, University of Dundee, Dundee, UK
    Immunol Rev 228:241-52. 2009
  7. pmc Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
    C David Wood
    Division of Cell Biology and Immunology, College of Life Sciences, MSI WTB CIR Complex, University of Dundee, Dow Street, Dundee, United Kingdom
    FEBS Lett 581:3494-8. 2007
  8. ncbi request reprint Regulation of protein kinase Cnu by the B-cell antigen receptor
    Sharon A Matthews
    Department of Pediatrics and Immunology, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98195, USA
    J Biol Chem 278:9086-91. 2003
  9. ncbi request reprint TRPML cation channels regulate the specialized lysosomal compartment of vertebrate B-lymphocytes
    Yumei Song
    Department of Pediatrics and Immunology, University of Washington and Children s Hospital and Regional Medical Center, Seattle, WA 98195, USA
    Eur J Cell Biol 85:1253-64. 2006

Collaborators

Detail Information

Publications9

  1. pmc Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues
    Sharon A Matthews
    Medical Research Institute, Ninewells Hospital and Medical School University of Dundee, Dundee, UK
    Eur J Immunol 42:1316-26. 2012
    ..Together, these results show that the PKD family does not play a critical role in lymphocyte integrin-mediated cell adhesion or lymphocyte trafficking in vivo...
  2. pmc Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes
    Sharon A Matthews
    Division of Cell Biology and Immunology, School of Life Sciences, University of Dundee, Scotland, United Kingdom
    Mol Cell Biol 26:1569-77. 2006
    ..These studies reveal an essential and redundant role for PKD enzymes in controlling class II HDACs in B lymphocytes and suggest that PKD serine kinases are a critical link between the BCR and epigenetic control of chromatin...
  3. pmc Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells
    Sharon A Matthews
    Ninewells Hospital, University of Dundee, Scotland, UK
    Biochem J 432:153-63. 2010
    ....
  4. pmc Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells
    Maria N Navarro
    The College of Life Sciences, Division of Cell Signalling and Immunology, The University of Dundee, Scotland, UK
    Biochem J 442:649-59. 2012
    ..Transcriptional profiling reveals the full consequences of PKD2 loss and maps in detail the selective, but critical, function for PKD2 in signalling by α/β mature TCR complexes in peripheral T-cells...
  5. pmc Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFkappaB activity in vertebrate B-cells
    Ping Liu
    Division of Cell Biology and Immunology, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK
    FEBS Lett 581:1377-82. 2007
    ..Thus, PKDs have a selective role in DT40 B-cell biology...
  6. pmc New insights into the regulation and function of serine/threonine kinases in T lymphocytes
    Sharon A Matthews
    Division of Medical Sciences, Centre for Oncology and Molecular Medicine, Ninewell s Hospital and Medical School, University of Dundee, Dundee, UK
    Immunol Rev 228:241-52. 2009
    ....
  7. pmc Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
    C David Wood
    Division of Cell Biology and Immunology, College of Life Sciences, MSI WTB CIR Complex, University of Dundee, Dow Street, Dundee, United Kingdom
    FEBS Lett 581:3494-8. 2007
    ..These results reveal that loss of PDK1 does not functionally inactivate all PKC-mediated signal transduction...
  8. ncbi request reprint Regulation of protein kinase Cnu by the B-cell antigen receptor
    Sharon A Matthews
    Department of Pediatrics and Immunology, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98195, USA
    J Biol Chem 278:9086-91. 2003
    ..Taken together, these results suggest that PKCnu is an important component of signaling pathways downstream from novel PKC enzymes after B-cell receptor engagement...
  9. ncbi request reprint TRPML cation channels regulate the specialized lysosomal compartment of vertebrate B-lymphocytes
    Yumei Song
    Department of Pediatrics and Immunology, University of Washington and Children s Hospital and Regional Medical Center, Seattle, WA 98195, USA
    Eur J Cell Biol 85:1253-64. 2006
    ..Endocytosed B-cell receptors were delivered to these enlarged lysosomes, demonstrating that a TRPML-dependent process is required for normal regulation of the specialized lysosome compartment of vertebrate B-lymphocytes...