Genomes and Genes
Affiliation: University College London
- The Anp32 family of proteins containing leucine-rich repeatsAntoni Matilla
Institute of Child Health, University College London, London, UK
Cerebellum 4:7-18. 2005....
- Molecular pathogenesis of spinocerebellar ataxiasAntoni Matilla Dueñas
Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
Brain 129:1357-70. 2006..Herein, we review the latest evidence for the proposed molecular processes to the pathogenesis of dominantly inherited spinocerebellar ataxias and the current therapeutic strategies...
- Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stressMiratul M K Muqit
Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK
J Neurochem 98:156-69. 2006..These observations provide valuable insights into the mechanisms of LB formation in PD that should lead to a better understanding of PD pathogenesis...
- Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesisPuneet Opal
Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA
J Biol Chem 278:34691-9. 2003..LANP thus could play a key role in neuronal development and/or neurodegeneration by its interactions with microtubule associated proteins...
- Anp32e/Cpd1 regulates protein phosphatase 2A activity at synapses during synaptogenesisRoxana V Costanzo
Centro Nacional de Genetica Medica, A N L I S, Programa Nacional de Genética Médica, Avenue, Las Heras 2670 1425, Buenos Aires, Argentina
Eur J Neurosci 23:309-24. 2006..Based on these observations, we propose that Anp32e/Cpd1 mediates synaptogenesis process by modulating PP2A activity...