Fernando O Martinez

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi Alternative activation of macrophages: an immunologic functional perspective
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom
    Annu Rev Immunol 27:451-83. 2009
  2. doi Regulators of macrophage activation
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Eur J Immunol 41:1531-4. 2011
  3. pmc The transcriptome of human monocyte subsets begins to emerge
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK
    J Biol 8:99. 2009
  4. pmc Essential role of DAP12 signaling in macrophage programming into a fusion-competent state
    Laura Helming
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Sci Signal 1:ra11. 2008
  5. doi Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences
    Fernando O Martinez
    Kennedy Rheumatology Institute, University of Oxford, Oxford, United Kingdom
    Blood 121:e57-69. 2013
  6. doi Alternative activation of macrophages: mechanism and functions
    Siamon Gordon
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Immunity 32:593-604. 2010
  7. doi Analysis of gene expression and gene silencing in human macrophages
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
    Curr Protoc Immunol . 2012
  8. pmc Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3
    Karl R Karlsson
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, UK
    Exp Hematol 36:1167-75. 2008
  9. pmc Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis
    Sigrid E M Heinsbroek
    Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
    PLoS Pathog 4:e1000218. 2008

Detail Information

Publications9

  1. doi Alternative activation of macrophages: an immunologic functional perspective
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom
    Annu Rev Immunol 27:451-83. 2009
    ..The evidence for in vivo alternative activation of macrophages is also analyzed, with nematode infection as prototypic disease. Finally, we revisit the concept of macrophage activation in the context of the immune response...
  2. doi Regulators of macrophage activation
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Eur J Immunol 41:1531-4. 2011
    ..In this issue of the European Journal of Immunology, two papers add to our understanding of how cellular kinases and phosphatases, related to the PI3K pathway, regulate M1 or M2 activation programmes in macrophages...
  3. pmc The transcriptome of human monocyte subsets begins to emerge
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK
    J Biol 8:99. 2009
    ..In papers published recently in the Journal of Proteome Research and in BMC Genomics, two groups publish independent transcriptome analyses of CD16(+) and CD16(-) monocytes, with revealing results...
  4. pmc Essential role of DAP12 signaling in macrophage programming into a fusion-competent state
    Laura Helming
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Sci Signal 1:ra11. 2008
    ..Thus, DAP12 is involved in programming of macrophages through the regulation of gene and protein expression to induce a fusion-competent state...
  5. doi Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences
    Fernando O Martinez
    Kennedy Rheumatology Institute, University of Oxford, Oxford, United Kingdom
    Blood 121:e57-69. 2013
    ....
  6. doi Alternative activation of macrophages: mechanism and functions
    Siamon Gordon
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Immunity 32:593-604. 2010
    ..The stage is now set to gain deeper insights into the role of alternatively activated macrophages in immunobiology...
  7. doi Analysis of gene expression and gene silencing in human macrophages
    Fernando O Martinez
    Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
    Curr Protoc Immunol . 2012
    ..The unit also includes a protocol for gene silencing in human macrophages. Altering gene expression can be useful to study the contribution of the gene to macrophage function or even expression of other genes...
  8. pmc Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3
    Karl R Karlsson
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, UK
    Exp Hematol 36:1167-75. 2008
    ..To develop a simple and efficient method for producing homogeneous populations of monocytes and macrophages from human embryonic stem cells (hES)...
  9. pmc Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis
    Sigrid E M Heinsbroek
    Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
    PLoS Pathog 4:e1000218. 2008
    ..albicans uptake. Our data suggest that pattern recognition receptors sample the fungal phagosome in a sequential fashion...