Stephen J Martin

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc The relationship between tetanus intensity and the magnitude of hippocampal long-term potentiation in vivo
    S J Martin
    Centre for Cognitive and Neural Systems, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, Scotland, UK
    Neuroscience 231:363-72. 2013
  2. ncbi request reprint Retrograde amnesia: neither partial nor complete hippocampal lesions in rats result in preferential sparing of remote spatial memory, even after reminding
    Stephen J Martin
    Laboratory for Cognitive Neuroscience, Division of Neuroscience, University of Edinburgh, Crichton Street, Edinburgh EH8 9LE, Scotland, UK
    Neuropsychologia 43:609-24. 2005
  3. ncbi request reprint Synaptic plasticity and memory: an evaluation of the hypothesis
    S J Martin
    Department and Centre for Neuroscience, University of Edinburgh, United Kingdom
    Annu Rev Neurosci 23:649-711. 2000
  4. ncbi request reprint Cortical plasticity: It's all the range!
    S J Martin
    Department of Neuroscience, University of Edinburgh, Crichton Street, EH8 9LE, Edinburgh, UK
    Curr Biol 11:R57-9. 2001
  5. ncbi request reprint Activation of metabotropic glutamate receptors induces gamma frequency oscillations in the rat dentate gyrus in vivo
    S J Martin
    Department of Neuroscience, University of Edinburgh, Crichton Street, Edinburgh EH8 9LE, UK
    Neuropharmacology 40:634-7. 2001
  6. ncbi request reprint New life in an old idea: the synaptic plasticity and memory hypothesis revisited
    S J Martin
    Hippocampus 12:609-36. 2002
  7. ncbi request reprint The rodent hippocampus and spatial memory: from synapses to systems
    S J Martin
    Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, University of Edinburgh, 1 George Square, Edinburgh, EH8 9JZ, UK
    Cell Mol Life Sci 64:401-31. 2007
  8. pmc Faster forgetting contributes to impaired spatial memory in the PDAPP mouse: deficit in memory retrieval associated with increased sensitivity to interference?
    Stephanie Daumas
    Centre for Cognitive and Neural Systems University of Edinburgh, Edinburgh EH8 9JZ, Scotland
    Learn Mem 15:625-32. 2008
  9. ncbi request reprint SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor
    Noboru H Komiyama
    Division of Neuroscience, University of Edinburgh, Edinburgh EH8 9JZ, United Kingdom
    J Neurosci 22:9721-32. 2002
  10. doi request reprint The postsubiculum and spatial learning: the role of postsubicular synaptic activity and synaptic plasticity in hippocampal place cell, object, and object-location memory
    David Bett
    Centre for Cognitive and Neural Systems, School of Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9JZ, United Kingdom
    J Neurosci 33:6928-43. 2013

Collaborators

Detail Information

Publications19

  1. pmc The relationship between tetanus intensity and the magnitude of hippocampal long-term potentiation in vivo
    S J Martin
    Centre for Cognitive and Neural Systems, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, Scotland, UK
    Neuroscience 231:363-72. 2013
    ..In conclusion, while tetanus intensity must exceed the LTP induction threshold, intensities above 500 μA should be avoided; in the present study, tetanization at 250-500 μA yielded maximal levels of LTP...
  2. ncbi request reprint Retrograde amnesia: neither partial nor complete hippocampal lesions in rats result in preferential sparing of remote spatial memory, even after reminding
    Stephen J Martin
    Laboratory for Cognitive Neuroscience, Division of Neuroscience, University of Edinburgh, Crichton Street, Edinburgh EH8 9LE, Scotland, UK
    Neuropsychologia 43:609-24. 2005
    ..The nature of this role--in the storage, retrieval, or expression of memory--is discussed...
  3. ncbi request reprint Synaptic plasticity and memory: an evaluation of the hypothesis
    S J Martin
    Department and Centre for Neuroscience, University of Edinburgh, United Kingdom
    Annu Rev Neurosci 23:649-711. 2000
    ..We conclude that a wealth of data supports the notion that synaptic plasticity is necessary for learning and memory, but that little data currently supports the notion of sufficiency...
  4. ncbi request reprint Cortical plasticity: It's all the range!
    S J Martin
    Department of Neuroscience, University of Edinburgh, Crichton Street, EH8 9LE, Edinburgh, UK
    Curr Biol 11:R57-9. 2001
    ..These findings support the view that activity-dependent synaptic plasticity is the brain's memory mechanism...
  5. ncbi request reprint Activation of metabotropic glutamate receptors induces gamma frequency oscillations in the rat dentate gyrus in vivo
    S J Martin
    Department of Neuroscience, University of Edinburgh, Crichton Street, Edinburgh EH8 9LE, UK
    Neuropharmacology 40:634-7. 2001
    ..The present study reveals that pharmacological activation of mGluRs in vivo induces dentate EEG oscillations at the low end of the gamma frequency range, with peak activity just below 30 Hz...
  6. ncbi request reprint New life in an old idea: the synaptic plasticity and memory hypothesis revisited
    S J Martin
    Hippocampus 12:609-36. 2002
    ..A major challenge will be to determine whether such changes constitute the memory trace itself or play a less specific supporting role in the information processing that accompanies memory formation...
  7. ncbi request reprint The rodent hippocampus and spatial memory: from synapses to systems
    S J Martin
    Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, University of Edinburgh, 1 George Square, Edinburgh, EH8 9JZ, UK
    Cell Mol Life Sci 64:401-31. 2007
    ....
  8. pmc Faster forgetting contributes to impaired spatial memory in the PDAPP mouse: deficit in memory retrieval associated with increased sensitivity to interference?
    Stephanie Daumas
    Centre for Cognitive and Neural Systems University of Edinburgh, Edinburgh EH8 9JZ, Scotland
    Learn Mem 15:625-32. 2008
    ..This interpretation of one aspect of the cognitive deficit in human mutant APP mice has parallels to deficits observed in patients with Alzheimer's disease, further supporting the validity of transgenic models of the disease...
  9. ncbi request reprint SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor
    Noboru H Komiyama
    Division of Neuroscience, University of Edinburgh, Edinburgh EH8 9JZ, United Kingdom
    J Neurosci 22:9721-32. 2002
    ..A comparison of SynGAP and PSD-95 mutants suggests that PSD-95 couples NMDARs to multiple downstream signaling pathways with very different roles in LTP and learning...
  10. doi request reprint The postsubiculum and spatial learning: the role of postsubicular synaptic activity and synaptic plasticity in hippocampal place cell, object, and object-location memory
    David Bett
    Centre for Cognitive and Neural Systems, School of Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9JZ, United Kingdom
    J Neurosci 33:6928-43. 2013
    ..However, plasticity in the postsubiculum is not necessary for the formation of new spatial maps...
  11. pmc Forgetting, reminding, and remembering: the retrieval of lost spatial memory
    Livia de Hoz
    Laboratory for Cognitive Neuroscience, Centre and Division of Neuroscience, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    PLoS Biol 2:E225. 2004
    ....
  12. doi request reprint Functional connectivity between the thalamus and postsubiculum: analysis of evoked responses elicited by stimulation of the laterodorsal thalamic nucleus in anesthetized rats
    Kate L Shires
    The University of Edinburgh, Centre for Cognitive and Neural Systems CCNS, 1 George Square, Edinburgh, EH8 9JZ, United Kingdom
    Hippocampus 23:559-69. 2013
    ..Infusion of CNQX almost completely abolished postsubicular fEPSPs, whereas D-AP5 had little effect. However, 60-Hz LTD was blocked by D-AP5 infusion, revealing that this form of synaptic plasticity is NMDA-receptor dependent...
  13. doi request reprint Upstairs/downstairs revisited: spatial pretraining-induced rescue of normal spatial learning during selective blockade of hippocampal N-methyl-d-aspartate receptors
    Jennifer Inglis
    Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, The University of Edinburgh, 1 George Square, Edinburgh, EH8 9JZ, UK
    Eur J Neurosci 37:718-27. 2013
    ..The implication of this paradoxical dissociation between hippocampal NMDA receptor-dependent plasticity and spatial learning is discussed with reference to two rival hypotheses of the impact of pretraining...
  14. pmc Dopaminergic modulation of the persistence of one-trial hippocampus-dependent memory
    Colin M O'Carroll
    Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, The University of Edinburgh, Edinburgh EH8 9JZ, United Kingdom
    Learn Mem 13:760-9. 2006
    ..The complementary effects of D1/D5 receptor blockade on the persistence of LTP and the duration of memory are consistent with the idea that changes in synaptic strength underlie memory...
  15. pmc Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memory
    R G M Morris
    Division of Centre for Neuroscience, The University of Edingurgh, Edinburgh, UK
    Philos Trans R Soc Lond B Biol Sci 358:773-86. 2003
    ....
  16. ncbi request reprint (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo
    S J Martin
    Centre for Neuroscience and Department of Pharmacology, University of Edinburgh, UK
    Neuropharmacology 36:1339-54. 1997
    ....
  17. ncbi request reprint Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloid
    Guiquan Chen
    Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, Edinburgh EH8 9JZ, United Kingdom
    J Neurosci 27:2654-62. 2007
    ....
  18. ncbi request reprint A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
    G Chen
    Department of Neuroscience, University of Edinburgh, UK
    Nature 408:975-9. 2000
    ....
  19. ncbi request reprint Interrogating rodents regarding their object and spatial memory
    Robert E Clark
    Department of Psychiatry, 0603 University of California San Diego and Veterans Affairs Medical Center, San Diego, La Jolla, CA 92093, USA
    Curr Opin Neurobiol 15:593-8. 2005
    ..Relevant to these issues, there have been substantial developments in the methods used to evaluate two of the most frequently studied forms of memory in the rodent -- recognition memory and spatial memory...