R M Martin

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. ncbi request reprint Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts
    Amy E Taylor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Am J Clin Nutr 91:547-56. 2010
  2. pmc Features of childhood cancer in primary care: a population-based nested case-control study
    R M Dommett
    School of Clinical Sciences, University of Bristol, Level 6 UHB Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK
    Br J Cancer 106:982-7. 2012
  3. pmc Filter paper blood spot enzyme linked immunoassay for adiponectin and application in the evaluation of determinants of child insulin sensitivity
    Richard M Martin
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 8:e71315. 2013
  4. pmc Trends in procedures for infertility and caesarean sections: was NICE disinvestment guidance implemented? NICE recommendation reminders
    Charlotte A Chamberlain
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    BMC Public Health 13:112. 2013
  5. pmc "Let's get the best quality research we can": public awareness and acceptance of consent to use existing data in health research: a systematic review and qualitative study
    Elizabeth M Hill
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, UK
    BMC Med Res Methodol 13:72. 2013
  6. pmc Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis
    Vanessa Y Tan
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol BS8 2PS, UK
    BMC Med 11:52. 2013
  7. pmc Effects of promoting longer-term and exclusive breastfeeding on adiposity and insulin-like growth factor-I at age 11.5 years: a randomized trial
    Richard M Martin
    School of Social and Community Medicine, University of Bristol, Bristol, England
    JAMA 309:1005-13. 2013
  8. pmc Filter paper blood spot enzyme linked immunoassay for insulin and application in the evaluation of determinants of child insulin resistance
    Richard M Martin
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e46752. 2012
  9. pmc Ongoing monitoring of data clustering in multicenter studies
    Lauren B Guthrie
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and the Harvard Pilgrim Health Care Institute, Boston, USA
    BMC Med Res Methodol 12:29. 2012
  10. ncbi request reprint Blood pressure and risk of prostate cancer: Cohort Norway (CONOR)
    Richard M Martin
    Department of Social Medicine, University of Bristol, UK
    Cancer Causes Control 21:463-72. 2010

Collaborators

Detail Information

Publications89

  1. ncbi request reprint Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts
    Amy E Taylor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Am J Clin Nutr 91:547-56. 2010
    ..Measures of regional adiposity have been proposed as alternatives to the measurement of body mass index (BMI) for identifying persons at risk of future disease...
  2. pmc Features of childhood cancer in primary care: a population-based nested case-control study
    R M Dommett
    School of Clinical Sciences, University of Bristol, Level 6 UHB Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK
    Br J Cancer 106:982-7. 2012
    ..This study investigated the risk of cancer in children with alert symptoms identified in current UK guidance, or with increased consultation frequency in primary care...
  3. pmc Filter paper blood spot enzyme linked immunoassay for adiponectin and application in the evaluation of determinants of child insulin sensitivity
    Richard M Martin
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 8:e71315. 2013
    ..We first describe the validation of an enzyme-linked immunoassay (ELISA) for quantifying adiponectin from dried blood spots and then demonstrate its application in a large trial (PROBIT)...
  4. pmc Trends in procedures for infertility and caesarean sections: was NICE disinvestment guidance implemented? NICE recommendation reminders
    Charlotte A Chamberlain
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    BMC Public Health 13:112. 2013
    ..We assess whether NICE guidance in 2004 and recommendation reminders were associated with a change in the rate of clinical procedures performed...
  5. pmc "Let's get the best quality research we can": public awareness and acceptance of consent to use existing data in health research: a systematic review and qualitative study
    Elizabeth M Hill
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, UK
    BMC Med Res Methodol 13:72. 2013
    ..We also investigated the effect of the provision of detailed information about the potential effect of selection bias on public acceptability of the use of data for research...
  6. pmc Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis
    Vanessa Y Tan
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol BS8 2PS, UK
    BMC Med 11:52. 2013
    ..Fascin-1 is an interesting candidate biomarker for aggressive, metastatic carcinomas but data from individual studies of human tumors have not yet been pooled systematically...
  7. pmc Effects of promoting longer-term and exclusive breastfeeding on adiposity and insulin-like growth factor-I at age 11.5 years: a randomized trial
    Richard M Martin
    School of Social and Community Medicine, University of Bristol, Bristol, England
    JAMA 309:1005-13. 2013
    ..Evidence that longer-term and exclusive breastfeeding reduces child obesity risk is based on observational studies that are prone to confounding...
  8. pmc Filter paper blood spot enzyme linked immunoassay for insulin and application in the evaluation of determinants of child insulin resistance
    Richard M Martin
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e46752. 2012
    ..We describe the development of an enzyme-linked immunoassay (ELISA) for quantifying insulin from dried blood spots and demonstrate its application in a large trial...
  9. pmc Ongoing monitoring of data clustering in multicenter studies
    Lauren B Guthrie
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and the Harvard Pilgrim Health Care Institute, Boston, USA
    BMC Med Res Methodol 12:29. 2012
    ..While it is possible to address and correct for some measurement error through statistical analysis, proactive data monitoring is essential to ensure high-quality data collection...
  10. ncbi request reprint Blood pressure and risk of prostate cancer: Cohort Norway (CONOR)
    Richard M Martin
    Department of Social Medicine, University of Bristol, UK
    Cancer Causes Control 21:463-72. 2010
    ..Some studies suggest that raised blood pressure may increase prostate cancer risk. We investigated associations of blood pressure with prostate cancer within the CONOR collaborative cohorts of Norway...
  11. ncbi request reprint Components of the metabolic syndrome and risk of prostate cancer: the HUNT 2 cohort, Norway
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Cancer Causes Control 20:1181-92. 2009
    ..The metabolic syndrome has been suggested as a unifying link between a "western" lifestyle and an increased prostate cancer risk...
  12. pmc Did intense adverse media publicity impact on prescribing of paroxetine and the notification of suspected adverse drug reactions? Analysis of routine databases, 2001-2004
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Br J Clin Pharmacol 61:224-8. 2006
    ..To document the impact on clinical practice in England of media attention around possible adverse effects of paroxetine...
  13. doi request reprint Associations of insulin-like growth factor (IGF)-I, IGF-II, IGF binding protein (IGFBP)-2 and IGFBP-3 with ultrasound measures of atherosclerosis and plaque stability in an older adult population
    Richard M Martin
    Department of Social Medicine, North Bristol, University of Bristol, Bristol BS8 2PR, United Kingdom
    J Clin Endocrinol Metab 93:1331-8. 2008
    ..Whether this association relates to alterations in plaque growth or stability, and the role of IGF-II and the major binding proteins [IGF binding protein (IGFBP)-2 and -3], is unclear...
  14. ncbi request reprint Associations of adiposity from childhood into adulthood with insulin resistance and the insulin-like growth factor system: 65-year follow-up of the Boyd Orr Cohort
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, United Kingdom
    J Clin Endocrinol Metab 91:3287-95. 2006
    ..One metabolic pathway through which adiposity influences disease risk may be via alterations in insulin and IGF metabolism...
  15. doi request reprint Does having been breastfed in infancy influence lipid profile in later life?: a review of the literature
    Richard M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    Adv Exp Med Biol 646:41-50. 2009
    ..The mechanistic basis for a programming effect of breastfeeding on adult cholesterol levels remains to be established in humans...
  16. pmc Continuing controversy over monitoring men with localized prostate cancer: a systematic review of programs in the prostate specific antigen era
    Richard M Martin
    Department of Social Medicine, University of Bristol, UK
    J Urol 176:439-49. 2006
    ..Current evidence on monitoring protocols and biomarkers used to predict disease progression was systematically reviewed...
  17. ncbi request reprint What was the immediate impact on population health of the recent fall in hormone replacement therapy prescribing in England? Ecological study
    Richard M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    J Public Health (Oxf) 32:555-64. 2010
    ..We investigated whether the subsequent 50% fall in HRT use in England impacted on population rates of these outcomes...
  18. ncbi request reprint Do gastrointestinal tract infections in infancy increase blood pressure in childhood? A cohort study
    R M Martin
    Department of Social Medicine, University of Bristol, 39 Whatley Road, Bristol BS8 2PS, UK
    J Epidemiol Community Health 64:1068-73. 2010
    ..In this study, the association between gastrointestinal tract infection in infancy, a clinically relevant exposure often accompanied by dehydration, and raised blood pressure in childhood was investigated...
  19. pmc Breast feeding in infancy and social mobility: 60-year follow-up of the Boyd Orr cohort
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Arch Dis Child 92:317-21. 2007
    ..To assess the association of having been breast fed with social class mobility between childhood and adulthood...
  20. pmc Commentary: prostate cancer is omnipresent, but should we screen for it?
    Richard M Martin
    Department of Social Medicine, University of Bristol, UK
    Int J Epidemiol 36:278-81. 2007
  21. ncbi request reprint Childhood diet and insulin-like growth factors in adulthood: 65-year follow-up of the Boyd Orr Cohort
    R M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Eur J Clin Nutr 61:1281-92. 2007
    ..We investigated associations of diet in childhood, in particular energy intake, with the IGF system in adulthood to determine if IGF-I - disease associations could be linked to early nutrition...
  22. pmc Does current evidence justify prostate cancer screening in Europe?
    Richard M Martin
    Epidemiology, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Nat Clin Pract Oncol 2:538-9. 2005
  23. ncbi request reprint Age- and gender-specific asthma death rates in patients taking long-acting beta2-agonists: prescription event monitoring pharmacosurveillance studies
    R M Martin
    Department of Social Medicine, University of Bristol, England
    Drug Saf 24:475-81. 2001
    ..This paper presents age- and gender-specific asthma death rates in patients prescribed the long-acting beta2-agonists salmeterol and bambuterol...
  24. pmc Association between breast feeding and growth: the Boyd-Orr cohort study
    R M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, UK
    Arch Dis Child Fetal Neonatal Ed 87:F193-201. 2002
    ..To investigate the association of breast feeding with height and body mass index in childhood and adulthood...
  25. pmc Population need for coronary revascularisation: are national targets for England credible?
    R M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
    Heart 88:627-33. 2002
    ..To estimate the need for coronary revascularisation, by using an incidence of indications approach, among 45-84 year olds with stable angina, unstable angina, and acute myocardial infarction...
  26. ncbi request reprint Infant nutrition and blood pressure in early adulthood: the Barry Caerphilly Growth study
    Richard M Martin
    Department of Social Medicine, University of Bristol, United Kingdom
    Am J Clin Nutr 77:1489-97. 2003
    ..Evidence suggests that environmental factors acting early in life may affect blood pressure in adulthood...
  27. ncbi request reprint Does breast-feeding in infancy lower blood pressure in childhood? The Avon Longitudinal Study of Parents and Children (ALSPAC)
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 109:1259-66. 2004
    ..Breast-feeding in infancy has been associated with decreased coronary heart disease mortality, but the underlying mechanisms are unclear. We investigated the association of breast-feeding with blood pressure in a contemporary cohort...
  28. ncbi request reprint Parents' growth in childhood and the birth weight of their offspring
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Epidemiology 15:308-16. 2004
    ..We investigated the influence of the childhood growth of the mother or father on the birth weight of their first-born offspring...
  29. ncbi request reprint Breastfeeding and cardiovascular mortality: the Boyd Orr cohort and a systematic review with meta-analysis
    Richard M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, Avon BS8 2PR, UK
    Eur Heart J 25:778-86. 2004
    ..To investigate the association of breastfeeding with all-cause, cardiovascular, and ischaemic heart disease mortality...
  30. pmc The rates of common adverse events reported during treatment with proton pump inhibitors used in general practice in England: cohort studies
    R M Martin
    University of Bristol, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, UK
    Br J Clin Pharmacol 50:366-72. 2000
    ..To estimate the rates of common adverse events in patients treated with the proton pump inhibitors omeprazole, lansoprazole and pantoprazole in general practice in England...
  31. ncbi request reprint Breastfeeding in infancy and blood pressure in later life: systematic review and meta-analysis
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    Am J Epidemiol 161:15-26. 2005
    ..Understanding the mechanism underlying this association may provide insights into pathways linking early life exposures with health in adulthood...
  32. ncbi request reprint Breast-feeding and cancer: the Boyd Orr cohort and a systematic review with meta-analysis
    Richard M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PR, United Kingdom
    J Natl Cancer Inst 97:1446-57. 2005
    ..We investigated associations between breast-feeding during infancy and adult cancer incidence and mortality in a cohort study and meta-analyses of published studies...
  33. ncbi request reprint Breast-feeding and childhood cancer: A systematic review with metaanalysis
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Int J Cancer 117:1020-31. 2005
    ..Our estimates suggest that increasing breast-feeding from 50% to 100% would prevent at most 5% of cases of childhood acute leukemia or lymphoma. (c) 2005 Wiley-Liss, Inc...
  34. pmc Breast feeding and cardiovascular disease risk factors, incidence, and mortality: the Caerphilly study
    Richard M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    J Epidemiol Community Health 59:121-9. 2005
    ..To investigate the association of having been breast fed with cardiovascular disease risk factors, incidence, and mortality...
  35. ncbi request reprint Breastfeeding and atherosclerosis: intima-media thickness and plaques at 65-year follow-up of the Boyd Orr cohort
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Arterioscler Thromb Vasc Biol 25:1482-8. 2005
    ..The impact of breastfeeding in infancy on cardiovascular disease risk is uncertain. We related breastfeeding in infancy to atherosclerosis in adulthood...
  36. ncbi request reprint Could associations between breastfeeding and insulin-like growth factors underlie associations of breastfeeding with adult chronic disease? The Avon Longitudinal Study of Parents and Children
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, UK
    Clin Endocrinol (Oxf) 62:728-37. 2005
    ..We investigated associations of having been breastfed with serum IGF-I and IGFBP-3 in childhood...
  37. doi request reprint The association of childhood height, leg length and other measures of skeletal growth with adult cardiovascular disease: the Boyd-Orr cohort
    E Whitley
    Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 66:18-23. 2012
    ..Associations with other aspects of skeletal size in childhood have not previously been investigated...
  38. pmc Features of cancer in teenagers and young adults in primary care: a population-based nested case-control study
    R M Dommett
    School of Clinical Sciences, University of Bristol, Level 6 UHB Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK
    Br J Cancer 108:2329-33. 2013
    ..Teenagers and young adults (TYA, 15-24 years) diagnosed with cancer report repeated visits to primary care before referral. We investigated associations of symptoms and consultation frequency in primary care with TYA cancers...
  39. pmc Current strategies for monitoring men with localised prostate cancer lack a strong evidence base: observational longitudinal study
    C Metcalfe
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, UK
    Br J Cancer 101:390-4. 2009
    ..However, there is little evidence of the changes in PSA level that should alert to the need for clinical re-assessment...
  40. pmc Mortality and morbidity surrounding coronary artery bypass surgery and the public presentation of risk
    R M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 56:430-1. 2002
  41. pmc Secular trends in prostate cancer mortality, incidence and treatment: England and Wales, 1975-2004
    Sabina Hussain
    Department of Social Medicine, University of Bristol, Bristol, UK
    BJU Int 101:547-55. 2008
    ....
  42. doi request reprint Latest results from the UK trials evaluating prostate cancer screening and treatment: the CAP and ProtecT studies
    J A Lane
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    Eur J Cancer 46:3095-101. 2010
    ..3% (10/442). The CAP and ProtecT trials (ISRCTN92187251 and ISRCTN20141217) will help resolve the prostate cancer screening debate, define the optimum treatment for localised disease and generate evidence to improve men's health...
  43. pmc Design and preliminary recruitment results of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP)
    E L Turner
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Br J Cancer 110:2829-36. 2014
    ....
  44. ncbi request reprint Genetic variants in the vitamin d receptor are associated with advanced prostate cancer at diagnosis: findings from the prostate testing for cancer and treatment study and a systematic review
    Lina Chen
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Cancer Epidemiol Biomarkers Prev 18:2874-81. 2009
    ..84; 95% confidence interval, 0.71-1.00; P(unadjusted) = 0.050; P(adjusted) = 0.014). Our finding provides some support for the hypothesis that low levels of vitamin D may increase the risk of prostate cancer progression...
  45. ncbi request reprint Cohort profile: The Boyd Orr cohort--an historical cohort study based on the 65 year follow-up of the Carnegie Survey of Diet and Health (1937-39)
    Richard M Martin
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Int J Epidemiol 34:742-9. 2005
  46. ncbi request reprint Haemoglobin A1c is not a surrogate for glucose and insulin measures for investigating the early life and childhood determinants of insulin resistance and Type 2 diabetes in healthy children. An analysis from the Avon Longitudinal Study of Parents and Chil
    W A Shultis
    Department of Social Medicine, University of Bristol, UK
    Diabet Med 23:1357-63. 2006
    ..We investigated haemoglobin A(1c) (HbA(1c)), a marker of glycaemia measured in non-fasting blood, as an alternative...
  47. pmc Low risk research using routinely collected identifiable health information without informed consent: encounters with the Patient Information Advisory Group
    C Metcalfe
    Department of Social Medicine, Bristol University, Bristol, UK
    J Med Ethics 34:37-40. 2008
    ..We conclude by arguing that many of the current problems could be avoided by returning PIAG's responsibilities to research ethics committees, and by allowing "opt-out" consent for many public health research projects...
  48. ncbi request reprint PTGS2-899G>C and prostate cancer risk: a population-based nested case-control study (ProtecT) and a systematic review with meta-analysis
    A Murad
    Department of Social Medicine, University of Bristol, Bristol, UK
    Prostate Cancer Prostatic Dis 12:296-300. 2009
    ..20). A meta-analysis of three studies also found little evidence that rs20417 alters risk (pooled OR(CC & GC v GG)=1.04, 95% CI=0.93-1.17), making it unlikely that rs20417 contributes in any major way to prostate cancer aetiology...
  49. pmc Life course sun exposure and risk of prostate cancer: population-based nested case-control study and meta-analysis
    Rebecca Gilbert
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Int J Cancer 125:1414-23. 2009
    ..The findings warrant further investigation because of their implications for vitamin D chemoprevention trials...
  50. pmc Population impact of regulatory activity restricting prescribing of COX-2 inhibitors: ecological study
    Benedict W Wheeler
    Department of Social Medicine, University of Bristol, Bristol, UK
    Br J Clin Pharmacol 68:752-64. 2009
    ..To investigate impacts of withdrawal and regulatory advice regarding cyclooxygenase-2 (COX-2) inhibitors on UK population rates of gastrointestinal haemorrhage and acute myocardial infarction (MI)...
  51. ncbi request reprint Patient outcomes and length of hospital stay after radical prostatectomy for prostate cancer: analysis of hospital episodes statistics for England
    Andrew Judge
    MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Bristol, UK
    BJU Int 100:1040-9. 2007
    ....
  52. doi request reprint The relation between adiposity throughout the life course and variation in IGFs and IGFBPs: evidence from the ProtecT (Prostate testing for cancer and Treatment) study
    Mari Anne Rowlands
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Cancer Causes Control 21:1829-42. 2010
    ..Adiposity is positively associated with advanced, metastatic, and fatal prostate cancer. Obesity-related variations in insulin-like growth factors (IGF-I and -II) and their binding proteins (IGFBPs) could underlie these associations...
  53. pmc Circulating folate, vitamin B12, homocysteine, vitamin B12 transport proteins, and risk of prostate cancer: a case-control study, systematic review, and meta-analysis
    Simon M Collin
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Cancer Epidemiol Biomarkers Prev 19:1632-42. 2010
    ..Disturbed folate metabolism is associated with an increased risk of some cancers. Our objective was to determine whether blood levels of folate, vitamin B(12), and related metabolites were associated with prostate cancer risk...
  54. ncbi request reprint International regulatory activity restricting COX-2 inhibitor use and deaths due to gastrointestinal haemorrhage and myocardial infarction
    Chris Metcalfe
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    Pharmacoepidemiol Drug Saf 19:778-85. 2010
    ..To investigate trends in mortality rates due to both myocardial infarction and gastrointestinal haemorrhage before and after rofecoxib withdrawal and the release of regulatory guidance regarding the use of other COX-2 inhibitors...
  55. ncbi request reprint Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer
    Simon M Collin
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Cancer Epidemiol Biomarkers Prev 19:2833-8. 2010
    ..We investigated whether these and other elements of folate metabolism were associated with prostate-specific antigen (PSA) velocity (PSAV) as a proxy measure of prostate cancer progression in men with localized prostate cancer...
  56. doi request reprint Associations of circulating and dietary vitamin D with prostate cancer risk: a systematic review and dose-response meta-analysis
    Rebecca Gilbert
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Cancer Causes Control 22:319-40. 2011
    ..We systematically reviewed and meta-analyzed literature examining associations of vitamin D (dietary intake, circulating 25-hydroxy-vitamin-D (25(OH)D), and 1,25-dihydroxy-vitamin-D (1,25(OH)(2)D) concentrations) with prostate cancer...
  57. pmc Prostate-cancer mortality in the USA and UK in 1975-2004: an ecological study
    Simon M Collin
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    Lancet Oncol 9:445-52. 2008
    ..Our aim was to study trends over time in prostate-cancer mortality and incidence in the USA and UK in 1975-2004, and compare these patterns with trends in screening and treatment...
  58. ncbi request reprint Association of body mass index measured in childhood, adolescence, and young adulthood with risk of ischemic heart disease and stroke: findings from 3 historical cohort studies
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
    Am J Clin Nutr 83:767-73. 2006
    ..It is unclear whether early life body mass index (BMI; in kg/m(2)) is associated with adult cardiovascular disease...
  59. ncbi request reprint Associations of childhood and adulthood height and the components of height with insulin-like growth factor levels in adulthood: a 65-year follow-up of the Boyd Orr cohort
    Isabelle Bray
    Defence Analytical Services Agency Health, Spur 7, Beckford Block, Ensleigh, Bath BA1 5AB, United Kingdom
    J Clin Endocrinol Metab 91:1382-9. 2006
    ..Taller individuals with longer legs have a higher risk of cancer but a lower risk of coronary heart disease...
  60. ncbi request reprint Oxycodone for cancer-related pain: meta-analysis of randomized controlled trials
    Colette M Reid
    Department of Palliative Medicine, University of Bristol, Bristol, England
    Arch Intern Med 166:837-43. 2006
    ..44) and lower compared with hydromorphone (-0.36; 95% CI, -0.71 to 0.00), although these effect sizes were small. The efficacy and tolerability of oxycodone are similar to morphine, supporting its use as an opioid for cancer-related pain...
  61. ncbi request reprint Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis
    Simon M Collin
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS United Kingdom
    Cancer Epidemiol Biomarkers Prev 18:2528-39. 2009
    ..Our meta-analysis suggests that known common folate-pathway single nucleotide polymorphisms do not have significant effects on susceptibility to prostate cancer...
  62. pmc Interleukin-18 polymorphism and physical functioning in older people: a replication study and meta-analysis
    Kate Thomas
    Department of Social Medicine, University of Bristol, Bristol BS8 2PS, UK
    J Gerontol A Biol Sci Med Sci 64:1177-82. 2009
    ..This variant has previously been associated with improved locomotor performance in old age, but the finding requires independent replication...
  63. ncbi request reprint Associations of lower urinary tract symptoms with prostate-specific antigen levels, and screen-detected localized and advanced prostate cancer: a case-control study nested within the UK population-based ProtecT (Prostate testing for cancer and Treatment)
    Simon M Collin
    Department of Social Medicine, University of Bristol, Bristol, UK
    BJU Int 102:1400-6. 2008
    ..To determine associations of lower urinary tract symptoms (LUTS) with prostate-specific antigen (PSA) levels and screen-detected localized and advanced prostate cancer...
  64. ncbi request reprint Lower urinary tract symptoms and risk of prostate cancer: the HUNT 2 Cohort, Norway
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Int J Cancer 123:1924-8. 2008
    ..Thus, screening for early cancers on the basis of LUTS may not be justified...
  65. doi request reprint Childhood circumstances and anthropometry: the Boyd Orr cohort
    Elise Whitley
    Department of Social Medicine, Bristol BS8 2PR, UK
    Ann Hum Biol 35:518-34. 2008
    ....
  66. ncbi request reprint Childhood stature and adult cancer risk: the Boyd Orr cohort
    Elise Whitley
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, England, UK
    Cancer Causes Control 20:243-51. 2009
    ..8+ years). There was no evidence that any of the five indicators of childhood growth was more strongly related to cancer risk than the other measures...
  67. pmc Circulating insulin-like growth factor peptides and prostate cancer risk: a systematic review and meta-analysis
    Mari Anne Rowlands
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Int J Cancer 124:2416-29. 2009
    ..Associations between IGFBP-3 and prostate cancer were inconsistent, and there was little evidence for a role of IGF-II, IGFBP-1 or IGFBP-2 in prostate cancer risk...
  68. ncbi request reprint International impacts of regulatory action to limit antidepressant prescribing on rates of suicide in young people
    Benedict W Wheeler
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Pharmacoepidemiol Drug Saf 18:579-88. 2009
    ..Antidepressant prescribing to young people in various countries declined, but subsequent analyses have demonstrated mixed effects on population suicide rates...
  69. pmc The population impact on incidence of suicide and non-fatal self harm of regulatory action against the use of selective serotonin reuptake inhibitors in under 18s in the United Kingdom: ecological study
    Benedict W Wheeler
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 336:542-5. 2008
    ..To investigate the population impact on the incidence of suicide and non-fatal self harm of regulatory action in 2003 to restrict the use of selective serotonin reuptake inhibitors (SSRIs) in under 18s...
  70. pmc Development of a new method for monitoring prostate-specific antigen changes in men with localised prostate cancer: a comparison of observational cohorts
    Kate Tilling
    Department of Social Medicine, Bristol University, Canynge Hall, Bristol, UK
    Eur Urol 57:446-52. 2010
    ..Prostate-specific antigen (PSA) measurements are increasingly used to monitor men with localised prostate cancer (PCa), but there is little consensus about the method to use...
  71. ncbi request reprint Associations of sexual dysfunction symptoms with PSA-detected localised and advanced prostate cancer: a case-control study nested within the UK population-based ProtecT (Prostate testing for cancer and Treatment) study
    Simon M Collin
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PS, UK
    Eur J Cancer 45:3254-61. 2009
    ..Conversely, among men with raised prostate-specific antigen (PSA) levels, a negative association might be expected if sexual dysfunction was symptomatic of benign, rather than malignant, prostatic disease...
  72. pmc The association of waiting times from diagnosis to surgery with survival in women with localised breast cancer in England
    M T Redaniel
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Br J Cancer 109:42-9. 2013
    ..Survival from breast cancer in the United Kingdom is lower than in other developed countries. It is unclear to what extent waiting times for curative surgery affect survival...
  73. ncbi request reprint Prostate cancer: screening approaches
    J L Donovan
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PR
    Br J Hosp Med (Lond) 66:623-6. 2005
    ..Current evidence about the impact and natural history of prostate cancer, screening and diagnostic tests, and the effectiveness of treatments is reviewed below...
  74. pmc Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database
    D Gunnell
    University of Bristol, Department of Social Medicine, University of Bristol, Bristol BS8 2PS
    BMJ 339:b3805. 2009
    ..To determine whether varenicline, a recently licensed smoking cessation product, is associated with an increased risk of suicide and suicidal behaviour compared with alternative treatments bupropion and nicotine replacement therapy...
  75. doi request reprint Population-based prostate-specific antigen testing in the UK leads to a stage migration of prostate cancer
    Alison L Moore
    Department of Social Medicine, University of Bristol, Bristol, UK
    BJU Int 104:1592-8. 2009
    ..To determine, within the UK, the stage and grade of prostate cancers that would be found through population-based prostate specific antigen (PSA) testing and biopsy...
  76. ncbi request reprint Statins and risk of cancer: a systematic review and metaanalysis
    Danielle R L Browning
    Faculty of Medicine and Dentistry, University of Bristol, Bristol, United Kingdom
    Int J Cancer 120:833-43. 2007
    ..lipophobic) or potency. Trial results were generally consistent with observational studies. We conclude that statin use is not associated with short-term cancer risk, but longer-latency effects remain possible...
  77. pmc NHS waiting lists and evidence of national or local failure: analysis of health service data
    Richard M Martin
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 326:188. 2003
    ..To investigate the national distribution of prolonged waiting for elective day case and inpatient surgery, and to examine associations of prolonged waiting with markers of NHS capacity, activity in the independent sector, and need...
  78. ncbi request reprint The association of atopic diseases with breast, prostate, and colorectal cancers: a meta-analysis
    Petra Vojtechova
    Faculty of Medicine and Dentistry, University of Bristol, Bristol, UK
    Cancer Causes Control 20:1091-105. 2009
    ..32, 0.69-2.53) cancers. There is little epidemiological support for the immune surveillance theory or antigenic stimulation theory in breast or colorectal carcinogenesis. The findings for prostate cancer warrant further investigation...
  79. pmc Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study
    Lesley Wood
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 336:601-5. 2008
    ..To examine whether the association of inadequate or unclear allocation concealment and lack of blinding with biased estimates of intervention effects varies with the nature of the intervention or outcome...
  80. ncbi request reprint Childhood body mass index and later cancer risk: a 50-year follow-up of the Boyd Orr study
    Mona Jeffreys
    Centre for Public Health Research, Massey University, Wellington, New Zealand
    Int J Cancer 112:348-51. 2004
    ..We conclude that childhood BMI is related to increased risk of cancer in later life, particularly smoking-related cancers...
  81. ncbi request reprint Effect of infant feeding on the risk of obesity across the life course: a quantitative review of published evidence
    Christopher G Owen
    Department of Community Health Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, United Kingdom
    Pediatrics 115:1367-77. 2005
    ..To examine the influence of initial infant feeding on obesity in later life...
  82. ncbi request reprint Does breastfeeding influence risk of type 2 diabetes in later life? A quantitative analysis of published evidence
    Christopher G Owen
    Division of Community Health Sciences, St George s, University of London, London, United Kingdom
    Am J Clin Nutr 84:1043-54. 2006
    ..Observational evidence suggests that having been breastfed in infancy may reduce the prevalence of type 2 diabetes in later life...
  83. ncbi request reprint The effect of breastfeeding on mean body mass index throughout life: a quantitative review of published and unpublished observational evidence
    Christopher G Owen
    Division of Community Health Sciences, St George s, University of London, London, United Kingdom
    Am J Clin Nutr 82:1298-307. 2005
    ..Evidence from observational studies has suggested that breastfeeding may reduce the prevalence of obesity in later life...
  84. ncbi request reprint Childhood dairy intake and adult cancer risk: 65-y follow-up of the Boyd Orr cohort
    Jolieke C van der Pols
    Longitudinal Studies Unit, Division of Epidemiology and Social Medicine, School of Population Health, University of Queensland, Brisbane, QLD, Australia
    Am J Clin Nutr 86:1722-9. 2007
    ..Evidence for a link between cancer risk and dairy consumption in adulthood is increasing, but associations with childhood dairy consumption have not been studied adequately...
  85. ncbi request reprint Does initial breastfeeding lead to lower blood cholesterol in adult life? A quantitative review of the evidence
    Christopher G Owen
    Division of Community Health Sciences, St George s, University of London, London, United Kingdom
    Am J Clin Nutr 88:305-14. 2008
    ..Earlier studies have suggested that infant feeding may program long-term changes in cholesterol metabolism...
  86. ncbi request reprint Effects of prolonged and exclusive breastfeeding on child height, weight, adiposity, and blood pressure at age 6.5 y: evidence from a large randomized trial
    Michael S Kramer
    Department of Pediatrics, McGill University Faculty of Medicine, Montreal, PQ, Canada
    Am J Clin Nutr 86:1717-21. 2007
    ..The evidence that breastfeeding protects against obesity and a variety of chronic diseases comes almost entirely from observational studies, which have a potential for bias due to confounding, selection bias, and selective publication...
  87. ncbi request reprint Infant feeding method and obesity: body mass index and dual-energy X-ray absorptiometry measurements at 9-10 y of age from the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Andre M Toschke
    Division of Health and Social Care Research, King s College London, United Kingdom
    Am J Clin Nutr 85:1578-85. 2007
    ..Previous studies reported inconsistent associations between breastfeeding and body mass index (BMI; in kg/m2). Associations with body fatness are unknown...
  88. ncbi request reprint Age-related increases in DNA repair and antioxidant protection: a comparison of the Boyd Orr Cohort of elderly subjects with a younger population sample
    Vikki Humphreys
    The Robert Gordon University, St Andrew Street, Aberdeen AB25 1HG, UK
    Age Ageing 36:521-6. 2007
    ..Accumulation of oxidative DNA damage with age will occur if there is an increase in reactive oxygen species in the body, or a decline in antioxidant defences, or a reduced efficiency of DNA repair...