PAUL B MARTIN

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. ncbi request reprint Obituary: julian hart lewis (1946-2014)
    Paul Martin
    School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK
    Development 141:2919-20. 2014
  2. pmc Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration
    Brian Stramer
    Department of Physiology, School of Medical Sciences, University of Bristol, Bristol, BS8 1TD, UK
    J Cell Biol 168:567-73. 2005
  3. pmc Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring
    Ryoichi Mori
    Department of Physiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
    J Exp Med 205:43-51. 2008
  4. pmc Modelling of human Wiskott-Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imaging
    Rebecca A Jones
    School of Biochemistry, Faculty of Medical and Veterinary Sciences, University of Bristol, University Walk, Bristol, BS8 1TD, UK
    J Cell Sci 126:4077-84. 2013
  5. pmc Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release
    William Razzell
    School of Biochemistry, Faculty of Medical and Veterinary Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK
    Curr Biol 23:424-9. 2013
  6. pmc Live imaging of tumor initiation in zebrafish larvae reveals a trophic role for leukocyte-derived PGE₂
    Yi Feng
    School of Biochemistry and School of Physiology and Pharmacology, Biomedical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, UK
    Curr Biol 22:1253-9. 2012
  7. pmc Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null mice
    Lisa Cooper
    Department of Anatomy and Developmental Biology, University College London, London, WC1E 6BT, UK
    Genome Biol 6:R5. 2005
  8. ncbi request reprint Morphogenesis: shroom in to close the neural tube
    Paul Martin
    Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, UK
    Curr Biol 14:R150-1. 2004
  9. ncbi request reprint Parallels between tissue repair and embryo morphogenesis
    Paul Martin
    Department of Physiology, University of Bristol, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
    Development 131:3021-34. 2004
  10. ncbi request reprint Inflammatory cells during wound repair: the good, the bad and the ugly
    Paul Martin
    Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, Bristol, UK BS8 1TD
    Trends Cell Biol 15:599-607. 2005

Research Grants

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Obituary: julian hart lewis (1946-2014)
    Paul Martin
    School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK
    Development 141:2919-20. 2014
    ..Paul Martin and David Ish-Horowicz look back on the life and work of their long-time friend and colleague Julian Lewis, who passed away on April 30th 2014. ..
  2. pmc Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration
    Brian Stramer
    Department of Physiology, School of Medical Sciences, University of Bristol, Bristol, BS8 1TD, UK
    J Cell Biol 168:567-73. 2005
    ..Cdc42 is necessary for maintaining cellular polarity and yet, despite in vitro evidence, is dispensable for sensing and crawling toward wound cues...
  3. pmc Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring
    Ryoichi Mori
    Department of Physiology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
    J Exp Med 205:43-51. 2008
    ..Thus, OPN and PDGF are potential targets for therapeutic modulation of skin repair to improve healing rate and quality...
  4. pmc Modelling of human Wiskott-Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imaging
    Rebecca A Jones
    School of Biochemistry, Faculty of Medical and Veterinary Sciences, University of Bristol, University Walk, Bristol, BS8 1TD, UK
    J Cell Sci 126:4077-84. 2013
    ..This model provides a unique insight into WASp-related immunodeficiency at both a cellular and whole organism level. ..
  5. pmc Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release
    William Razzell
    School of Biochemistry, Faculty of Medical and Veterinary Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK
    Curr Biol 23:424-9. 2013
    ..Therefore, calcium represents the earliest signal in the wound inflammatory response...
  6. pmc Live imaging of tumor initiation in zebrafish larvae reveals a trophic role for leukocyte-derived PGE₂
    Yi Feng
    School of Biochemistry and School of Physiology and Pharmacology, Biomedical Sciences Building, University of Bristol, University Walk, Bristol BS8 1TD, UK
    Curr Biol 22:1253-9. 2012
    ..Our in vivo observations at these early stages of cancer initiation provide a potential mechanistic explanation for why long-term use of low doses of NSAIDs, including aspirin, might reduce cancer onset...
  7. pmc Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null mice
    Lisa Cooper
    Department of Anatomy and Developmental Biology, University College London, London, WC1E 6BT, UK
    Genome Biol 6:R5. 2005
    ..Tissue damage also triggers a robust influx of inflammatory leukocytes to the wound site that play key roles in clearing the wound of invading microbes but also release signals that may be detrimental to repair and lead to fibrosis...
  8. ncbi request reprint Morphogenesis: shroom in to close the neural tube
    Paul Martin
    Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, UK
    Curr Biol 14:R150-1. 2004
    ....
  9. ncbi request reprint Parallels between tissue repair and embryo morphogenesis
    Paul Martin
    Department of Physiology, University of Bristol, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
    Development 131:3021-34. 2004
    ..In the embryo, both morphogenesis and repair are achieved with a perfect end result, whereas repair of adult tissues leads to scarring. We discuss whether this may be due to the adult inflammatory response, which is absent in the embryo...
  10. ncbi request reprint Inflammatory cells during wound repair: the good, the bad and the ugly
    Paul Martin
    Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, Bristol, UK BS8 1TD
    Trends Cell Biol 15:599-607. 2005
    ....
  11. ncbi request reprint The inflammation-fibrosis link? A Jekyll and Hyde role for blood cells during wound repair
    Brian M Stramer
    Department of Physiology, School of Medical Sciences, University of Bristol, Bristol, UK
    J Invest Dermatol 127:1009-17. 2007
    ....
  12. pmc Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closure
    Thomas H Millard
    Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1DA, UK
    Development 135:621-6. 2008
    ..Finally, we characterise the behaviour of a patched-expressing cell that we observe within the engrailed region of segments A1-A5, and provide evidence that this cell contributes to cell matching...
  13. doi request reprint Analysis of WASp function during the wound inflammatory response--live-imaging studies in zebrafish larvae
    Ana Cvejic
    Departments of Biochemistry and Physiology, School of Medical Sciences, University of Bristol, Bristol, UK
    J Cell Sci 121:3196-206. 2008
    ....
  14. pmc Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos
    Brian Stramer
    Department of Physiology, School of Medical Sciences, University of Bristol, UK
    EMBO Rep 9:465-71. 2008
    ....
  15. ncbi request reprint Cell biology: master regulators of sealing and healing
    Brian Stramer
    Department of Physiology and Biochemistry, University of Bristol, UK
    Curr Biol 15:R425-7. 2005
    ..Yet new evidence suggests a conserved transcription factor, Grainyhead, controls both their development and the means by which both structures repair themselves...
  16. ncbi request reprint Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration
    Ryoichi Mori
    Department of Physiology, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK
    J Cell Sci 119:5193-203. 2006
    ....
  17. pmc Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes
    Tanya Shaw
    Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol, UK
    EMBO Rep 10:881-6. 2009
    ....
  18. doi request reprint Prioritization of competing damage and developmental signals by migrating macrophages in the Drosophila embryo
    Severina Moreira
    Department of Biochemistry and Department of Physiology and Pharmacology, University of Bristol, BS8 1TD Bristol, UK
    Curr Biol 20:464-70. 2010
    ....

Research Grants1

  1. 2005 Tissue Repair and Regeneration Gordon Conferences
    Paul Martin; Fiscal Year: 2005
    ..The combination of speakers and topics has been selected with the specific intention of stimulating new ideas and collaborations in the field of tissue repair. ..