Research Topics
Species | C M Martin-RuizSummaryAffiliation: University of Newcastle Country: UK Publications
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Detail Information
Publications
Human brain nicotinic receptors, their distribution and participation in neuropsychiatric disordersA J Graham
Joint MRC-University of Newcastle upon Tyne, Centre Development in Clinical Brain Ageing, MRC Building, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK
Curr Drug Targets CNS Neurol Disord 1:387-97. 2002..It is possible that the development of nAChR subtype specific drugs may lead to advances in therapy for both age-related and psychiatric disorders...
The Newcastle 85+ study: biological, clinical and psychosocial factors associated with healthy ageing: study protocolJoanna Collerton
Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK
BMC Geriatr 7:14. 2007....
Molecular analysis of nicotinic receptor expression in autismC M Martin-Ruiz
Joint MRC University of Newcastle upon Tyne, Centre Development in Clinical Brain Ageing, Department of Neuropathology, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK
Brain Res Mol Brain Res 123:81-90. 2004..The findings point to dendritic and/or synaptic nicotinic receptor abnormalities that may relate to disruptions in cerebral circuitry development...
Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrainE K Perry
Centre Development in Clinical Brain Ageing, Newcastle General Hospital, Newcastle upon Tyne, UK
Am J Psychiatry 158:1058-66. 2001..Measures of cholinergic transmitter activity were investigated in patients with autism because of reported neuropathological abnormalities in cholinergic nuclei in the basal forebrain...
Nicotinic receptor subtypes in human brain related to aging and dementiaE K Perry
Joint MRC-Newcastle University Centre Development in Clinical Brain Ageing, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK
Alcohol 24:63-8. 2001..Correlations exist between some of these receptor abnormalities and clinical and pathological features of the diseases. Targeting such receptors is a current therapeutic objective...
Immunohistochemical localisation of nicotinic acetylcholine receptor subunits in human cerebellumA Graham
Joint MRC University of Newcastle upon Tyne, Centre Development in Clinical Brain Ageing, MRC Building, Newcastle General Hospital, Westgate Road, NE4 6BE, Newcastle upon Tyne, UK
Neuroscience 113:493-507. 2002..Further investigations are warranted to evaluate the participation of nicotinic acetylcholine receptors in cerebellar pathology associated with both developmental and age-related disorders...
Telomeres as biomarkers for ageing and age-related diseasesT von Zglinicki
Henry Wellcome Laboratory for Biogerontology Research, Newcastle General Hospital, School of Clinical Medical Sciences-Gerontology, University of Newcastle, Newcastle upon Tyne, NE4 6BE, UK
Curr Mol Med 5:197-203. 2005....
