Research Topics
Genomes and Genes | Adele L MarstonSummaryAffiliation: University of Edinburgh Country: UK Publications
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Publications
Meiosis: DDK is not just for replicationAdele L Marston
The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK
Curr Biol 19:R74-6. 2009..How is the chromosome segregation machinery modified to segregate homologs during meiosis I? The Dbf4-dependent Cdc7 kinase (DDK) has now been identified as a key regulator in this process...
Cdc55 coordinates spindle assembly and chromosome disjunction during meiosisFarid Bizzari
Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, Scotland, UK
J Cell Biol 193:1213-28. 2011..Therefore, Cdc55 orders passage through the meiotic divisions by ensuring a balance of phosphatases...
Shugoshin prevents cohesin cleavage by PP2A(Cdc55)-dependent inhibition of separaseDean Clift
The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
Genes Dev 23:766-80. 2009..We propose that Cdc55 is a separase inhibitor that acts downstream from Shugoshin under conditions where sister chromatids are not under tension...
Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3Josefin Fernius
The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
PLoS Genet 5:e1000629. 2009..We propose that the Ctf19 complex ensures additional loading of cohesin at centromeres prior to passage of the replication fork, thereby ensuring its incorporation into functional linkages through a process requiring Csm3...
