Adele L Marston

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3
    Josefin Fernius
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Genet 5:e1000629. 2009
  2. pmc Cdc55 coordinates spindle assembly and chromosome disjunction during meiosis
    Farid Bizzari
    Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, Scotland, UK
    J Cell Biol 193:1213-28. 2011
  3. pmc Cohesin-dependent association of scc2/4 with the centromere initiates pericentromeric cohesion establishment
    Josefin Fernius
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, Michael Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK
    Curr Biol 23:599-606. 2013
  4. pmc The role of shugoshin in meiotic chromosome segregation
    D Clift
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK
    Cytogenet Genome Res 133:234-42. 2011
  5. pmc Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms
    Adele L Marston
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom
    Genetics 196:31-63. 2014
  6. pmc Meiosis: DDK is not just for replication
    Adele L Marston
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK
    Curr Biol 19:R74-6. 2009
  7. pmc Shugoshin prevents cohesin cleavage by PP2A(Cdc55)-dependent inhibition of separase
    Dean Clift
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Genes Dev 23:766-80. 2009
  8. pmc Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation
    Olga O Nerusheva
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom
    Genes Dev 28:1291-309. 2014

Collaborators

  • Juri Rappsilber
  • Josefin Fernius
  • Olga O Nerusheva
  • Farid Bizzari
  • Stefan Galander
  • D Clift
  • Dean Clift
  • David Kelly
  • Flavia de Lima Alves

Detail Information

Publications9

  1. pmc Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3
    Josefin Fernius
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Genet 5:e1000629. 2009
    ..We propose that the Ctf19 complex ensures additional loading of cohesin at centromeres prior to passage of the replication fork, thereby ensuring its incorporation into functional linkages through a process requiring Csm3...
  2. pmc Cdc55 coordinates spindle assembly and chromosome disjunction during meiosis
    Farid Bizzari
    Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, Scotland, UK
    J Cell Biol 193:1213-28. 2011
    ..Therefore, Cdc55 orders passage through the meiotic divisions by ensuring a balance of phosphatases...
  3. pmc Cohesin-dependent association of scc2/4 with the centromere initiates pericentromeric cohesion establishment
    Josefin Fernius
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, Michael Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK
    Curr Biol 23:599-606. 2013
    ..Overall, our findings provide a paradigm for the spatial and temporal control of cohesin loading...
  4. pmc The role of shugoshin in meiotic chromosome segregation
    D Clift
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK
    Cytogenet Genome Res 133:234-42. 2011
    ..Recent studies have begun to uncover the mechanisms underlying this stepwise loss of cohesion in meiosis and the role of a conserved protein, shugoshin, in regulating this process...
  5. pmc Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms
    Adele L Marston
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom
    Genetics 196:31-63. 2014
    ..Here, I review the pioneering work from budding yeast that has led to a molecular understanding of the establishment and destruction of cohesion. ..
  6. pmc Meiosis: DDK is not just for replication
    Adele L Marston
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Mayfield Road, Edinburgh EH9 3JR, UK
    Curr Biol 19:R74-6. 2009
    ..How is the chromosome segregation machinery modified to segregate homologs during meiosis I? The Dbf4-dependent Cdc7 kinase (DDK) has now been identified as a key regulator in this process...
  7. pmc Shugoshin prevents cohesin cleavage by PP2A(Cdc55)-dependent inhibition of separase
    Dean Clift
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Genes Dev 23:766-80. 2009
    ..We propose that Cdc55 is a separase inhibitor that acts downstream from Shugoshin under conditions where sister chromatids are not under tension...
  8. pmc Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation
    Olga O Nerusheva
    The Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom
    Genes Dev 28:1291-309. 2014
    ..Disassembly of this platform in response to intersister kinetochore tension signals the bioriented state. Therefore, tension sensing by shugoshin is a central mechanism by which the bioriented state is read. ..