I Marshall

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi Reproducibility of metabolite peak areas in 1H MRS of brain
    I Marshall
    Department of Medical Physics and Medical Engineering, University of Edinburgh, UK
    Magn Reson Imaging 14:281-92. 1996
  2. ncbi MRI and CFD studies of pulsatile flow in healthy and stenosed carotid bifurcation models
    Ian Marshall
    Department of Medical and Radiological Sciences, Medical Physics, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    J Biomech 37:679-87. 2004
  3. ncbi Repeatability of long and short echo-time in vivo proton chemical-shift imaging
    I Marshall
    SHEFC Brain Imaging Research Centre for Scotland, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Neuroradiology 44:973-80. 2002
  4. ncbi Choice of spectroscopic lineshape model affects metabolite peak areas and area ratios
    I Marshall
    Department of Medical Physics, University of Edinburgh, Edinburgh, Scotland
    Magn Reson Med 44:646-9. 2000
  5. ncbi Brain choline concentration. Early quantitative marker of ischemia and infarct expansion?
    B Karaszewski
    SFC Brain Imaging Research Centre, SINAPSE Collaboration, Division of Clinical Neurosciences, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, UK
    Neurology 75:850-6. 2010
  6. ncbi Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome
    J M Wardlaw
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Scotland
    Stroke 29:1618-24. 1998
  7. ncbi Normalisation of metabolite images in 1H NMR spectroscopic imaging
    J M Wild
    Department of Medical Physics and Medical Engineering, University of Edinburgh, Western General Hospital, UK
    Magn Reson Imaging 15:1057-66. 1997
  8. ncbi Diffusion anisotropy measurements in ischaemic stroke of the human brain
    P A Armitage
    Department of Medical Physics, University of Edinburgh, Western General Hospital, UK
    MAGMA 6:28-36. 1998
  9. ncbi Quantitative analysis of PC MRI velocity maps: pulsatile flow in cylindrical vessels
    M B Robertson
    Department of Medical Physics and Medical Engineering, University of Edinburgh, Western General Hospital, Crewe Road, EH4 2XU, Edinburgh, United Kingdom
    Magn Reson Imaging 19:685-95. 2001
  10. ncbi 1H spectroscopic imaging of acute head injury--evidence of diffuse axonal injury
    J M Wild
    Department of Medical Physics, University of Edinburgh, Western General Hospital, Scotland, UK
    MAGMA 8:109-15. 1999

Collaborators

Detail Information

Publications48

  1. ncbi Reproducibility of metabolite peak areas in 1H MRS of brain
    I Marshall
    Department of Medical Physics and Medical Engineering, University of Edinburgh, UK
    Magn Reson Imaging 14:281-92. 1996
    ....
  2. ncbi MRI and CFD studies of pulsatile flow in healthy and stenosed carotid bifurcation models
    Ian Marshall
    Department of Medical and Radiological Sciences, Medical Physics, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    J Biomech 37:679-87. 2004
    ..In the normal phantom, the converse was found, with a low flow region near the outer wall of the bulb. Time-averaged WSS and oscillatory shear index were also markedly different for the two phantoms...
  3. ncbi Repeatability of long and short echo-time in vivo proton chemical-shift imaging
    I Marshall
    SHEFC Brain Imaging Research Centre for Scotland, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Neuroradiology 44:973-80. 2002
    ..The magnitude of the CVs needs to be taken into account in the calculation of sample size for cross-sectional or linear studies...
  4. ncbi Choice of spectroscopic lineshape model affects metabolite peak areas and area ratios
    I Marshall
    Department of Medical Physics, University of Edinburgh, Edinburgh, Scotland
    Magn Reson Med 44:646-9. 2000
    ..An explanation of this previously unreported effect is given. This finding clearly has serious implications for the methodology and reporting of spectroscopic studies...
  5. ncbi Brain choline concentration. Early quantitative marker of ischemia and infarct expansion?
    B Karaszewski
    SFC Brain Imaging Research Centre, SINAPSE Collaboration, Division of Clinical Neurosciences, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, UK
    Neurology 75:850-6. 2010
    ....
  6. ncbi Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome
    J M Wardlaw
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Scotland
    Stroke 29:1618-24. 1998
    ....
  7. ncbi Normalisation of metabolite images in 1H NMR spectroscopic imaging
    J M Wild
    Department of Medical Physics and Medical Engineering, University of Edinburgh, Western General Hospital, UK
    Magn Reson Imaging 15:1057-66. 1997
    ..These results confirm that normalisation of PRESS localised images does have a significant bearing upon any quantitative measurements made using such images...
  8. ncbi Diffusion anisotropy measurements in ischaemic stroke of the human brain
    P A Armitage
    Department of Medical Physics, University of Edinburgh, Western General Hospital, UK
    MAGMA 6:28-36. 1998
    ..27 (p = 0.003) and 0.87 +/- 0.05 (p = 0.005) respectively. The effects of gradient interactions, image registration, noise contamination and rotational variance and their implications for the results obtained in this study are discussed...
  9. ncbi Quantitative analysis of PC MRI velocity maps: pulsatile flow in cylindrical vessels
    M B Robertson
    Department of Medical Physics and Medical Engineering, University of Edinburgh, Western General Hospital, Crewe Road, EH4 2XU, Edinburgh, United Kingdom
    Magn Reson Imaging 19:685-95. 2001
    ..Evaluation of the analytical models allowed an estimate of the inherent accuracy in the measurement of velocity maps and WSS values...
  10. ncbi 1H spectroscopic imaging of acute head injury--evidence of diffuse axonal injury
    J M Wild
    Department of Medical Physics, University of Edinburgh, Western General Hospital, Scotland, UK
    MAGMA 8:109-15. 1999
    ..This suggests that SI (of NAA in particular) will be useful for the diagnosis of diffuse axonal injury...
  11. ncbi Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke
    Vera Cvoro
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, UK
    Stroke 40:767-72. 2009
    ..We used spectroscopic imaging to measure N-acetyl aspartate (NAA, a marker of normal neurons) and lactate (a marker of ischemia) to compare with diffusion and perfusion values in the diffusion lesion in acute ischemic stroke...
  12. ncbi Flow in elliptical vessels calculated for a physiological waveform
    M B Robertson
    Department of Medical Physics and Medical Engineering, University of Edingburgh, Western General Hospital, Edinburgh, UK
    J Vasc Res 38:73-82. 2001
    ..8). The temporal average wall shear stress, which has been associated with atherogenic sites, also displayed a minimum at the end of the major axis that decreased with more elliptical cross-sections...
  13. ncbi A theoretical study of the effect of experimental noise on the measurement of anisotropy in diffusion imaging
    M E Bastin
    Department of Medical Physics and Medical Engineering, University of Edinburgh, Western General Hospital, Scotland, UK
    Magn Reson Imaging 16:773-85. 1998
    ....
  14. ncbi Changes in NAA and lactate following ischemic stroke: a serial MR spectroscopic imaging study
    S Muñoz Maniega
    University of Edinburgh, Division of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK
    Neurology 71:1993-9. 2008
    ..We assessed the temporal pattern of neuronal loss and ischemia after ischemic stroke using magnetic resonance spectroscopic imaging (MRSI) and diffusion-weighted imaging (DWI)...
  15. ncbi Functional imaging as a predictor of schizophrenia
    Heather C Whalley
    Division of Psychiatry, University of Edinburgh, Edinburgh, Scotland, UK
    Biol Psychiatry 60:454-62. 2006
    ..These differences are detectable with fMRI and may have clinical utility...
  16. ncbi MRI measurement of wall shear stress vectors in bifurcation models and comparison with CFD predictions
    U Kohler
    Medical Physics, Department of Medical and Radiological Sciences, University of Edinburgh, Edinburgh, UK
    J Magn Reson Imaging 14:563-73. 2001
    ..The combination of MRI and CFD would seem to be a powerful technique for the investigation of flow phenomena...
  17. ncbi Diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy (1H MRS) in schizophrenic subjects and normal controls
    R M Steel
    University of Edinburgh, Department of Psychiatry, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, EH10 5HF, Edinburgh, UK
    Psychiatry Res 106:161-70. 2001
    ....
  18. ncbi In vivo lactate editing in single voxel proton spectroscopy and proton spectroscopic imaging by homonuclear polarisation transfer
    J M Wild
    Department of Medical Physics and Medical Engineering, University of Edinburgh, Western General Hospital, UK
    Magn Reson Imaging 17:131-9. 1999
    ..The technique is an effective method of separating the overlapping signals of lactate and lipids. Furthermore this editing method can be performed without state of the art MRI scanner hardware...
  19. ncbi MRI measurement of time-resolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions
    Panorea Papathanasopoulou
    Medical Physics, Department of Medical and Radiological Sciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, Scotland, UK
    J Magn Reson Imaging 17:153-62. 2003
    ..CONCLUSION: This is the first report of time-resolved WSS vectors estimated from 3D-MRI data. The technique worked well except in regions of disturbed flow, where the combination with CFD modeling is clearly advantageous...
  20. ncbi Reduction of cingulate gray matter density in poor outcome bipolar illness
    Alan Doris
    SHEFC Brain Imaging Center for Scotland, University of Edinburgh, Edinburgh, UK
    Psychiatry Res 130:153-9. 2004
    ..Although causality of these changes is difficult to resolve, the results offer useful insights into the neural correlates of severe bipolar disorder...
  21. ncbi Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature
    C S A Macmillan
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Acta Neurochir (Wien) 144:853-62; discussion 862. 2002
    ..Increased choline and creatine were found in SAH patients suggestive of increased cell-wall turnover. Current theories of brain injury after TBI or SAH do not explain these observed neurochemical changes and further research is required...
  22. ncbi Assessment of factors affecting MRI measurement of intracranial volume changes and elastance index
    I Marshall
    Medical Physics, Division of Medical and Radiological Sciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Br J Neurosurg 22:389-97. 2008
    ..Because of these difficulties, caution is required in the interpretation of results obtained from a single examination. Techniques and methods that may reduce the variability in the derived hydrodynamic parameters are discussed...
  23. ncbi fMRI correlates of state and trait effects in subjects at genetically enhanced risk of schizophrenia
    H C Whalley
    Division of Psychiatry, University of Edinburgh, Edinburgh EH10 5HF, UK
    Brain 127:478-90. 2004
    ....
  24. ncbi Choline and creatine are not reliable denominators for calculating metabolite ratios in acute ischemic stroke
    Susana Muñoz Maniega
    University of Edinburgh, Division of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK
    Stroke 39:2467-9. 2008
    ..Choline and creatine are commonly used as denominators for other metabolites in ischemic stroke spectroscopy, assuming that they do not change. We investigated their concentration variation over time after stroke...
  25. ncbi MR diffusion and perfusion parameters: relationship to metabolites in acute ischaemic stroke
    Vera Cvoro
    SFC Brain Imaging Research Centre, SINAPSE Collaboration, Division of Clinical Neuroscience, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 81:185-91. 2010
    ..The authors compared N-acetyl aspartate (NAA, found in intact neurons) and lactate (anaerobic metabolism) with diffusion/perfusion parameters...
  26. ncbi Reproducibility of GABA measurements using 2D J-resolved magnetic resonance spectroscopy
    Katherine Lymer
    Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, UK
    Magn Reson Imaging 25:634-40. 2007
    ..In vivo, the CV for GABA measurement was 26%, suggesting that 2D J-resolved MRS would be suitable for detecting physiological changes in GABA, similar to those reported using other methods...
  27. ncbi Measurement of regional brain temperature using proton spectroscopic imaging: validation and application to acute ischemic stroke
    Ian Marshall
    SHEFC Brain Imaging Research Centre for Scotland, University of Edinburgh, Edinburgh, UK
    Magn Reson Imaging 24:699-706. 2006
    ..45 degrees C (hotter)-2.17 degrees C (cooler)]. Noninvasive temperature measurement by SI has sufficient precision to be used in studies of pathophysiology in stroke and in other brain disorders and to monitor therapies...
  28. ncbi Computational simulations and experimental studies of 3D phase-contrast imaging of fluid flow in carotid bifurcation geometries
    Ian Marshall
    Medical Physics and Medical Engineering, Division of Medical and Radiological Sciences, University of Edinburgh, Edinburgh, UK
    J Magn Reson Imaging 31:928-34. 2010
    ....
  29. ncbi Feasibility of k-t BLAST technique for measuring "seven-dimensional" fluid flow
    Ian Marshall
    Medical Physics and SHEFC Brain Imaging Research Centre for Scotland, University of Edinburgh, Edinburgh, UK
    J Magn Reson Imaging 23:189-96. 2006
    ..To investigate the feasibility of rapid MR measurement of "seven-dimensional" (three velocity components, three dimensions, and time) fluid flow using the k-t Broad-use Linear Acquisition Speed-Up Technique (BLAST)...
  30. ncbi Functional disconnectivity in subjects at high genetic risk of schizophrenia
    Heather C Whalley
    Division of Psychiatry, School of Informatics, University of Edinburgh, Edinburgh, Scotland
    Brain 128:2097-108. 2005
    ..These connectivity abnormalities may underlie the diverse deficits seen in the established condition and the more subtle deficits seen in close relatives of those with the disorder...
  31. ncbi Repeatability of motor and working-memory tasks in healthy older volunteers: assessment at functional MR imaging
    Ian Marshall
    Department of Medical Physics, SHEFC Brain Imaging Research Center, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, Scotland, UK
    Radiology 233:868-77. 2004
    ..To prospectively determine the repeatability of functional magnetic resonance (MR) imaging brain activation tasks in a group of healthy older male volunteers...
  32. ncbi The functional anatomy of inspection time: an event-related fMRI study
    Ian J Deary
    Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, Edinburgh, EH8 9JZ, UK
    Neuroimage 22:1466-79. 2004
    ..fMRI can thus reveal information about the neural correlates of mental events which occur over very short durations...
  33. ncbi Carotid flow rates and flow division at the bifurcation in healthy volunteers
    Ian Marshall
    Medical Physics, Division of Medical and Radiological Sciences, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK
    Physiol Meas 25:691-7. 2004
    ..70, 0.39 and 0.26, respectively. The data will be of use in future physiological studies and in computational modelling of carotid artery haemodynamics...
  34. ncbi Real-time functional magnetic resonance imaging (rt-fMRI) in patients with brain tumours: preliminary findings using motor and language paradigms
    C Schwindack
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Br J Neurosurg 19:25-32. 2005
    ..Further paradigm development is required for evaluation of language, and possibly other more complex executive functions...
  35. ncbi Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging
    J M Starr
    SHEFC Centre for the Study of the Ageing Brain, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK
    J Neurol Neurosurg Psychiatry 74:70-6. 2003
    ..Increased permeability of the BBB might account for some of the cerebral effects of type II diabetes, and so possibly also for the effect of other conditions that affect the microvasculature (like hypertension), on the brain...
  36. ncbi Reduction of electromagnetic interference from a commercially available MR-compatible flow simulator
    M B Robertson
    Department of Medical Physics and Medical Engineering, University of Edinburgh, Western General Hospital, UK
    J Med Eng Technol 24:28-31. 2000
    ..The results demonstrate the elimination of EMI and a significant improvement in image quality...
  37. ncbi Forced convective head cooling device reduces human cross-sectional brain temperature measured by magnetic resonance: a non-randomized healthy volunteer pilot study
    B A Harris
    School of Clinical Sciences and Community Health, University of Edinburgh, Edinburgh, UK
    Br J Anaesth 100:365-72. 2008
    ..This pilot study in five healthy adult humans forms the pre-clinical assessment of the effect of a forced convective head cooling device on intracranial temperature, measured non-invasively by magnetic resonance spectroscopy (MRS)...
  38. ncbi Quantification of MRS data in the frequency domain using a wavelet filter, an approximated Voigt lineshape model and prior knowledge
    P Gillies
    School of Mathematics and Statistics, Napier University, Edinburgh, UK
    NMR Biomed 19:617-26. 2006
    ..Again, the same reduced parameter model gave the lowest value for chi(2) in each case...
  39. ncbi Event-related fMRI of word classification and successful word recognition in subjects at genetically enhanced risk of schizophrenia
    Marie-Claire Whyte
    Division of Psychiatry, University of Edinburgh, UK
    Psychol Med 36:1427-39. 2006
    ..This is consistent with a leftward shift of the inverted 'U' load-response model of cognitive function in schizophrenia...
  40. ncbi Early brain temperature elevation and anaerobic metabolism in human acute ischaemic stroke
    Bartosz Karaszewski
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Rd, Edinburgh, EH4 2XU, UK
    Brain 132:955-64. 2009
    ..Further studies are required to determine why early brain temperature elevation is highest in potential penumbral tissue...
  41. ncbi Episodic and semantic memory tasks activate different brain regions in Alzheimer disease
    J M Starr
    Geriatric Medicine Unit, University of Edinburgh, UK
    Neurology 65:266-9. 2005
    ..To compare brain activity identified by fMRI in subjects with Alzheimer disease (AD) and older healthy controls (HCs) performing an episodic/working memory (EWM) and semantic memory (SM) task...
  42. ncbi The use of ultrasound to diagnose hepatic steatosis in type 2 diabetes: intra- and interobserver variability and comparison with magnetic resonance spectroscopy
    R M Williamson
    Metabolic Unit, Western General Hospital, Royal Infirmary of Edinburgh, Little France Crescent, Edinburgh, UK
    Clin Radiol 66:434-9. 2011
    ....
  43. ncbi Induced hyperammonemia alters neuropsychology, brain MR spectroscopy and magnetization transfer in cirrhosis
    Sherzad Balata
    Liver Unit, Royal Infirmary of Edinburgh, Edinburgh, Scotland
    Hepatology 37:931-9. 2003
    ..Induced hyperammonemia resulted in an increase in brain Glx/Cr ratio and a decrease in MTR, which may indicate an increase in brain water as the operative mechanism...
  44. ncbi Functional Magnetic Resonance Imaging (fMRI) reproducibility and variance components across visits and scanning sites with a finger tapping task
    Viktoria Eleni Gountouna
    Division of Psychiatry, The University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK
    Neuroimage 49:552-60. 2010
    ....
  45. ncbi Magnetic resonance spectroscopy and cognitive function in healthy elderly men
    Karen J Ferguson
    Brain Imaging Research Centre for Scotland, Edinburgh, UK
    Brain 125:2743-9. 2002
    ..These results suggest that in healthy men aged 65-70 years, metabolite levels relate to cognitive performance. Rising Cr levels may be an early marker of cognitive decline...
  46. ncbi Quantitative comparison of CFD predicted and MRI measured velocity fields in a carotid bifurcation phantom
    Quan Long
    Department of Chemical Engineering and Chemical Technology, Imperial College, London, UK
    Biorheology 39:467-74. 2002
    ..897 (average 0.939) where the velocity profiles were skewed, than along the anterior-posterior axis (average correlation factor 0.876) where the velocity profiles were in M-shape...
  47. ncbi Brain activation and the phonological loop: the impact of rehearsal
    Robert H Logie
    Department of Psychology, University of Aberdeen, AB24 3FX, Aberdeen, UK
    Brain Cogn 53:293-6. 2003
    ..Our results should be relatively free of the influence of other mental operations, and emphasise the importance of considering which cognitive strategies might give rise to focused or to diverse patterns of brain activation...
  48. ncbi Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke
    Bartosz Karaszewski
    Department of Neurology of Adults, Medical University of Gdansk, Gdansk, Poland
    Ann Neurol 60:438-46. 2006
    ....