Andrew K Marshall
Affiliation: University of Reading
- A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3)Stephen J Fuller
School of Biological Sciences, University of Reading, Whiteknights Campus, UK
Biochem J 442:595-610. 2012..MST3(Thr(178)/Thr(328)) phosphorylation was concurrent with dissociation of MST3 from GOLGA2/gm130 and association of MST3 with MO25, and MST3(Thr(328)) phosphorylation was necessary for formation of the activated MST3-MO25 holocomplex...
- SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactionsPeter H Sugden
School of Biological Sciences, University of Reading, Whiteknights Campus, Harborne Building, Reading RG6 6AS, U K
Biochem J 454:13-30. 2013..Finally, we consider the association of GCKIIIs with a number of human diseases, particularly cerebral cavernous malformations. ..
- Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically activePeter H Sugden
Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Whiteknights, Reading RG6 6UB, UK
Cell Signal 23:468-77. 2011....
- Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulinThomais Markou
National Heart and Lung Institute Cardiovascular Sciences, Faculty of Medicine, Imperial College London, London, UK
BMC Genomics 11:343. 2010..Here, we used microarrays to compare the effects of endothelin-1 and insulin on the global transcriptome of neonatal rat cardiomyocytes, and on mRNA recruitment to polysomes (i.e. the translatome)...