Stephen P Marsden

Summary

Affiliation: University of Leeds
Country: UK

Publications

  1. ncbi request reprint Catalytic aza-Wittig cyclizations for heteroaromatic synthesis
    Stephen P Marsden
    School of Chemistry, University of Leeds, Leeds, UK
    Org Lett 10:2589-91. 2008
  2. doi request reprint Facile and general synthesis of quaternary 3-aminooxindoles
    Stephen P Marsden
    School of Chemistry, University of Leeds, Leeds LS2 9JT, UK
    Org Lett 10:2905-8. 2008
  3. ncbi request reprint Electrophile-directed diastereoselective alkylation of prochiral enediolates
    Stephen P Marsden
    School of Chemistry, University of Leeds, Leeds, UK
    J Am Chem Soc 129:12600-1. 2007
  4. doi request reprint Catalyst control in sequential asymmetric allylic substitution: stereodivergent access to N,N-diprotected unnatural amino acids
    Paolo Tosatti
    School of Chemistry, University of Leeds, LS2 9JT Leeds, UK
    J Org Chem 76:5495-501. 2011
  5. ncbi request reprint Efficient asymmetric synthesis of quaternary (E)-vinylglycines by deconjugative alkylation of dehydroamino acids
    Matthew C Jones
    School of Chemistry, University of Leeds, Leeds LS2 9JT, UK
    Org Lett 8:5509-12. 2006
  6. doi request reprint Recent advances and applications of iridium-catalysed asymmetric allylic substitution
    Paolo Tosatti
    School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK
    Org Biomol Chem 10:3147-63. 2012
  7. doi request reprint Synthesis of benzazoles by hydrogen-transfer catalysis
    A John Blacker
    School of Chemistry and Institute of Process Research and Development, University of Leeds, Leeds LS2 9JT, UK
    Org Lett 11:2039-42. 2009
  8. ncbi request reprint Isotopic labeling for determination of enantiomeric purity by 2H NMR spectroscopy
    Hayley Jackman
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    Org Lett 9:5179-82. 2007
  9. ncbi request reprint Deconjugation of dehydroamino acids: stereoselective synthesis of racemic (E)-vinylglycines
    Paul A Alexander
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    Org Lett 7:5433-6. 2005
  10. doi request reprint Alkene hydroboration: hot intermediates that react while they are cooling
    David R Glowacki
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Am Chem Soc 132:13621-3. 2010

Collaborators

  • Paolo Tosatti
  • Adam Nelson
  • A John Blacker
  • Jeremy N Harvey
  • David R Glowacki
  • John G Cumming
  • Matthew C Jones
  • Duanpen Lertpibulpanya
  • Carlo Sambiagio
  • J Mikael Hillgren
  • Joachim Horn
  • Hayley Jackman
  • John H Cassidy
  • Dulce M Muñoz Subtil
  • Tito Akindele
  • Paul A Alexander
  • Steven M Miles
  • Patrick C McGowan
  • Gordon G Weingarten
  • David House
  • Peter Shapland
  • Simon Barrett
  • Anders Pedersen
  • Christopher N Farthing
  • Colin A Kilner
  • Ignacio Rodriguez-Garcia
  • Geoffrey Stemp
  • Mark Slater
  • John C Reader
  • William J Coates
  • Robin J Leatherbarrow

Detail Information

Publications19

  1. ncbi request reprint Catalytic aza-Wittig cyclizations for heteroaromatic synthesis
    Stephen P Marsden
    School of Chemistry, University of Leeds, Leeds, UK
    Org Lett 10:2589-91. 2008
    ..Catalyst loadings down to 1 mol % have been used with little or no loss in reaction efficiency. The intimate involvement of the phosphine oxide in the catalytic cycle has been verified by in situ infrared spectroscopy...
  2. doi request reprint Facile and general synthesis of quaternary 3-aminooxindoles
    Stephen P Marsden
    School of Chemistry, University of Leeds, Leeds LS2 9JT, UK
    Org Lett 10:2905-8. 2008
    ..The cyclization of N-indolyl-substituted substrates is accompanied by direct C-H arylation of the indole, leading to indolo-fused benzodiazepines...
  3. ncbi request reprint Electrophile-directed diastereoselective alkylation of prochiral enediolates
    Stephen P Marsden
    School of Chemistry, University of Leeds, Leeds, UK
    J Am Chem Soc 129:12600-1. 2007
  4. doi request reprint Catalyst control in sequential asymmetric allylic substitution: stereodivergent access to N,N-diprotected unnatural amino acids
    Paolo Tosatti
    School of Chemistry, University of Leeds, LS2 9JT Leeds, UK
    J Org Chem 76:5495-501. 2011
    ....
  5. ncbi request reprint Efficient asymmetric synthesis of quaternary (E)-vinylglycines by deconjugative alkylation of dehydroamino acids
    Matthew C Jones
    School of Chemistry, University of Leeds, Leeds LS2 9JT, UK
    Org Lett 8:5509-12. 2006
    ..The products can be converted to valuable quaternary beta-amino alcohols by chemoselective reduction. [reaction: see text]...
  6. doi request reprint Recent advances and applications of iridium-catalysed asymmetric allylic substitution
    Paolo Tosatti
    School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK
    Org Biomol Chem 10:3147-63. 2012
    ....
  7. doi request reprint Synthesis of benzazoles by hydrogen-transfer catalysis
    A John Blacker
    School of Chemistry and Institute of Process Research and Development, University of Leeds, Leeds LS2 9JT, UK
    Org Lett 11:2039-42. 2009
    ..Transition-metal-catalyzed hydrogen-transfer reactions have been used for the conversion of alcohols into benzimidazoles and aldehydes into benzoxazoles and benzothiazoles...
  8. ncbi request reprint Isotopic labeling for determination of enantiomeric purity by 2H NMR spectroscopy
    Hayley Jackman
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    Org Lett 9:5179-82. 2007
    ..The assays allow for simple semiquantitative analysis of asymmetric transformations...
  9. ncbi request reprint Deconjugation of dehydroamino acids: stereoselective synthesis of racemic (E)-vinylglycines
    Paul A Alexander
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    Org Lett 7:5433-6. 2005
    ..The key step involves the kinetic alpha-protonation of dianionic dienolates derived from dehydroamino acids...
  10. doi request reprint Alkene hydroboration: hot intermediates that react while they are cooling
    David R Glowacki
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Am Chem Soc 132:13621-3. 2010
    ....
  11. doi request reprint Total synthesis of the immunosuppressants myriocin and 2-epi-myriocin
    Matthew C Jones
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    Org Lett 10:4125-8. 2008
    ..The key transformations are the efficient synthesis of a quaternary (E)-vinylglycine by asymmetric deconjugative alkylation of a dehydroamino acid and an unusually highly diastereoselective dihydroxylation of the vinylglycine alkene...
  12. doi request reprint Convenient synthesis of 3-alkoxy-3-aryloxindoles by intramolecular arylation of mandelic amides
    J Mikael Hillgren
    School of Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Org Chem 73:6459-61. 2008
    ..Medicinally important 3-alkoxy-3-aryloxindoles are conveniently prepared by the rapid microwave-promoted palladium-catalyzed intramolecular enolate arylation of mandelate-derived anilides...
  13. doi request reprint Convergent, regiospecific synthesis of quinolines from o-aminophenylboronates
    Joachim Horn
    School of Chemistry, University of Leeds, Leeds LS2 9JT, UK
    Org Lett 10:4117-20. 2008
    ..Quinolines substituted in the benzenoid ring can be accessed by using substituted o-aminophenylboronates prepared by direct palladium-catalyzed borylation of the corresponding o-bromoanilines...
  14. ncbi request reprint Copper catalysed Ullmann type chemistry: from mechanistic aspects to modern development
    Carlo Sambiagio
    iPRD, School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK
    Chem Soc Rev 43:3525-50. 2014
    ..Finally, recent developments in green chemistry for these reactions, such as reactions in aqueous media and heterogeneous catalysis, have also been reviewed...
  15. ncbi request reprint Stereocontrolled assembly of tetrasubstituted tetrahydrofurans: a concise synthesis of virgatusin
    Tito Akindele
    School of Chemistry, University of Leeds, Leeds LS2 9JT, U K
    Org Lett 7:3685-8. 2005
    ..The reaction has been applied to a concise (nine step) synthesis of (+)-virgatusin (ent-1). [reaction: see text]..
  16. ncbi request reprint A concise, convergent total synthesis of monocerin
    John H Cassidy
    Department of Chemistry, Imperial College, London, SW7 2AY, UK
    Org Biomol Chem 4:4118-26. 2006
    ..The synthesis was ultimately completed by a strategy involving stepwise oxidative cleavage of the C3-ethenyl substituent...
  17. ncbi request reprint Asymmetric aza-Wittig reactions: enantioselective synthesis of beta-quaternary azacycles
    Duanpen Lertpibulpanya
    Department of Chemistry, Imperial College London, London SW72AY, UK
    Angew Chem Int Ed Engl 45:5000-2. 2006
  18. ncbi request reprint Concise access to indolizidine and pyrroloazepine skeleta via intramolecular Schmidt reactions of azido 1,3-diketones
    Duanpen Lertpibulpanya
    Department of Chemistry, Imperial College, London, UK SW7 2AY
    Org Biomol Chem 4:3498-504. 2006
    ..Chiral aluminium-based Lewis acids could also be used to mediate this symmetry-breaking transformation, but no significant asymmetric induction was observed...
  19. ncbi request reprint Synthesis and bio-assay of RCM-derived Bowman-Birk inhibitor analogues
    Steven M Miles
    Department of Chemistry, Imperial College London, South Kensington Campus, London, UKSW7 2AZ
    Org Biomol Chem 2:281-3. 2004
    ....