Petros Marangos

Summary

Affiliation: University College London
Country: UK

Publications

  1. doi request reprint Oocytes progress beyond prophase in the presence of DNA damage
    Petros Marangos
    Department of Cell and Developmental Biology, Division of Biosciences, University College London, Gower Street, London WC1E 6BT, UK
    Curr Biol 22:989-94. 2012
  2. pmc Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1)
    Petros Marangos
    Department of Physiology, University College London, London WC1E 6BT, England, UK
    J Cell Biol 176:65-75. 2007
  3. doi request reprint Securin regulates entry into M-phase by modulating the stability of cyclin B
    Petros Marangos
    Department of Cell and Developmental Biology, Division of Biosciences, University College London, Gower Street, London, WC1E 6BT, UK
    Nat Cell Biol 10:445-51. 2008
  4. ncbi request reprint The dynamics of cyclin B1 distribution during meiosis I in mouse oocytes
    Petros Marangos
    Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK
    Reproduction 128:153-62. 2004
  5. ncbi request reprint Fertilization and InsP3-induced Ca2+ release stimulate a persistent increase in the rate of degradation of cyclin B1 specifically in mature mouse oocytes
    Petros Marangos
    Department of Physiology, University College London, WC1E 6BT, UK
    Dev Biol 272:26-38. 2004
  6. ncbi request reprint Ca2+ oscillations at fertilization in mammals are regulated by the formation of pronuclei
    Petros Marangos
    Department of Physiology, UCL, Gower Street, London WC1E 6BT, UK
    Development 130:1461-72. 2003
  7. ncbi request reprint Sperm-triggered [Ca2+] oscillations and Ca2+ homeostasis in the mouse egg have an absolute requirement for mitochondrial ATP production
    Remi Dumollard
    Department of Physiology, University College London, Gower Street, London, WC1E 6BT, UK
    Development 131:3057-67. 2004
  8. ncbi request reprint Ca2+ signalling and cortical re-organisation during the transition from meiosis to mitosis in mammalian oocytes
    John Carroll
    Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK
    Eur J Obstet Gynecol Reprod Biol 115:S61-7. 2004
  9. ncbi request reprint Changes in endoplasmic reticulum structure during mouse oocyte maturation are controlled by the cytoskeleton and cytoplasmic dynein
    Greg FitzHarris
    Department of Physiology, University College London, University College London, Gower Street, London WC1E 6BT, UK
    Dev Biol 305:133-44. 2007
  10. ncbi request reprint Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity
    Ibtissem Nabti
    Department of Cell and Developmental Biology, University College London, London WC1E 6BT, England, UK
    J Cell Biol 204:891-900. 2014

Detail Information

Publications11

  1. doi request reprint Oocytes progress beyond prophase in the presence of DNA damage
    Petros Marangos
    Department of Cell and Developmental Biology, Division of Biosciences, University College London, Gower Street, London WC1E 6BT, UK
    Curr Biol 22:989-94. 2012
    ..We conclude that oocytes are the only nontransformed cells that fail to launch a robust G2 phase DNA damage checkpoint and that this renders them sensitive to genomic instability...
  2. pmc Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1)
    Petros Marangos
    Department of Physiology, University College London, London WC1E 6BT, England, UK
    J Cell Biol 176:65-75. 2007
    ..Finally, we show that Emi1-dependent effects on meiosis I require the presence of Cdh1. These observations reveal a novel mechanism for the control of entry into the first meiotic division: an Emi1-dependent inhibition of APC(Cdh1)...
  3. doi request reprint Securin regulates entry into M-phase by modulating the stability of cyclin B
    Petros Marangos
    Department of Cell and Developmental Biology, Division of Biosciences, University College London, Gower Street, London, WC1E 6BT, UK
    Nat Cell Biol 10:445-51. 2008
    ..These data reveal a role for securin at the G2-M transition and suggest a more general mechanism whereby physiological levels of co-competing APC substrates function in modulating the timing of cell-cycle transitions...
  4. ncbi request reprint The dynamics of cyclin B1 distribution during meiosis I in mouse oocytes
    Petros Marangos
    Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK
    Reproduction 128:153-62. 2004
    ..These studies show that GVBD in mouse oocytes is sensitive to cyclin B1 abundance and that the changes in distribution of cyclin B1 contribute to progression through MI...
  5. ncbi request reprint Fertilization and InsP3-induced Ca2+ release stimulate a persistent increase in the rate of degradation of cyclin B1 specifically in mature mouse oocytes
    Petros Marangos
    Department of Physiology, University College London, WC1E 6BT, UK
    Dev Biol 272:26-38. 2004
    ..Furthermore, this Ca2+ -induced increase in degradation of cyclin B1 requires factors specific to mature oocytes, and that to overcome arrest at MII, Ca2+ acts to release the CSF-mediated brake on cyclin B1 destruction...
  6. ncbi request reprint Ca2+ oscillations at fertilization in mammals are regulated by the formation of pronuclei
    Petros Marangos
    Department of Physiology, UCL, Gower Street, London WC1E 6BT, UK
    Development 130:1461-72. 2003
    ..We conclude by suggesting a model where nuclear sequestration and release of a Ca(2+)-releasing activity contributes to the temporal organization of Ca(2+) transients in meiosis and mitosis in mice...
  7. ncbi request reprint Sperm-triggered [Ca2+] oscillations and Ca2+ homeostasis in the mouse egg have an absolute requirement for mitochondrial ATP production
    Remi Dumollard
    Department of Physiology, University College London, Gower Street, London, WC1E 6BT, UK
    Development 131:3057-67. 2004
    ..As mitochondrial ATP generation is essential to sustain the [Ca2+] signals that are crucial to initiate development, mitochondrial integrity is clearly fundamental in sustaining fertility in mammalian eggs...
  8. ncbi request reprint Ca2+ signalling and cortical re-organisation during the transition from meiosis to mitosis in mammalian oocytes
    John Carroll
    Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK
    Eur J Obstet Gynecol Reprod Biol 115:S61-7. 2004
    ..These changes in organisation have implications for the inheritance of ER in meiotic and mitotic cell divisions and may reflect different roles and requirements for Ca(2+) in meiosis and mitosis...
  9. ncbi request reprint Changes in endoplasmic reticulum structure during mouse oocyte maturation are controlled by the cytoskeleton and cytoplasmic dynein
    Greg FitzHarris
    Department of Physiology, University College London, University College London, Gower Street, London WC1E 6BT, UK
    Dev Biol 305:133-44. 2007
    ....
  10. ncbi request reprint Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity
    Ibtissem Nabti
    Department of Cell and Developmental Biology, University College London, London WC1E 6BT, England, UK
    J Cell Biol 204:891-900. 2014
    ..These findings demonstrate new roles for MAPK in the regulation of meiosis in mammalian oocytes. ..
  11. pmc Cell cycle-dependent regulation of structure of endoplasmic reticulum and inositol 1,4,5-trisphosphate-induced Ca2+ release in mouse oocytes and embryos
    Greg FitzHarris
    Department of Obstetrics and Gynaecology and the Assisted Conception Unit, University College London, London, WC1E 6BT
    Mol Biol Cell 14:288-301. 2003
    ....