Teresa Marafioti

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma
    T Marafioti
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, UK
    Leukemia 19:856-61. 2005
  2. doi Novel markers of normal and neoplastic human plasmacytoid dendritic cells
    Teresa Marafioti
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Blood 111:3778-92. 2008
  3. ncbi Expression of intracellular signaling molecules in classical and lymphocyte predominance Hodgkin disease
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, United Kingdom
    Blood 103:188-93. 2004
  4. ncbi Phenotype and genotype of interfollicular large B cells, a subpopulation of lymphocytes often with dendritic morphology
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, United Kingdom
    Blood 102:2868-76. 2003
  5. pmc Expression of B-lymphocyte-associated transcription factors in human T-cell neoplasms
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, United Kingdom
    Am J Pathol 162:861-71. 2003
  6. ncbi Leucocyte-specific protein (LSP1) in malignant lymphoma and Hodgkin's disease
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 120:671-8. 2003
  7. ncbi The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas
    Teresa Marafioti
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 128:333-42. 2005
  8. ncbi Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples
    Michela Pozzobon
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 124:519-33. 2004
  9. ncbi The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas
    Jennifer C Paterson
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK
    Haematologica 91:772-80. 2006
  10. ncbi Leukocyte-specific phosphoprotein-1 and PU.1: two useful markers for distinguishing T-cell-rich B-cell lymphoma from lymphocyte-predominant Hodgkin's disease
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
    Haematologica 89:957-64. 2004

Detail Information

Publications35

  1. ncbi Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma
    T Marafioti
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, UK
    Leukemia 19:856-61. 2005
    ....
  2. doi Novel markers of normal and neoplastic human plasmacytoid dendritic cells
    Teresa Marafioti
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Blood 111:3778-92. 2008
    ....
  3. ncbi Expression of intracellular signaling molecules in classical and lymphocyte predominance Hodgkin disease
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, United Kingdom
    Blood 103:188-93. 2004
    ..Furthermore, the clear difference in expression of signaling proteins between the 2 major subtypes of Hodgkin disease may be of diagnostic value...
  4. ncbi Phenotype and genotype of interfollicular large B cells, a subpopulation of lymphocytes often with dendritic morphology
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, United Kingdom
    Blood 102:2868-76. 2003
    ..Studies in experimental animals should help to elucidate the role of these cells in the immune response...
  5. pmc Expression of B-lymphocyte-associated transcription factors in human T-cell neoplasms
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, United Kingdom
    Am J Pathol 162:861-71. 2003
    ....
  6. ncbi Leucocyte-specific protein (LSP1) in malignant lymphoma and Hodgkin's disease
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 120:671-8. 2003
    ....
  7. ncbi The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas
    Teresa Marafioti
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 128:333-42. 2005
    ..It would be of interest to correlate this feature with patterns of gene expression and also with prognosis, since it may identify a subset of human lymphoma that is distinct in its molecular and clinical features...
  8. ncbi Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples
    Michela Pozzobon
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 124:519-33. 2004
    ..The observation that a range of leucocyte signalling molecules can be detected in routine biopsies offers new possibilities for studying normal and neoplastic human white cells in diagnostic tissue samples...
  9. ncbi The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas
    Jennifer C Paterson
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK
    Haematologica 91:772-80. 2006
    ..It was hypothesized that their expression patterns might yield information on apoptosis as it occurs in normal and reactive lymphoid cells, and also be of value for the detection of lymphoma subtypes...
  10. ncbi Leukocyte-specific phosphoprotein-1 and PU.1: two useful markers for distinguishing T-cell-rich B-cell lymphoma from lymphocyte-predominant Hodgkin's disease
    Teresa Marafioti
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
    Haematologica 89:957-64. 2004
    ..In this paper, we have evaluated the usefulness of the pan-leukocyte marker LSP1 and the transcription factor PU.1 for resolving such diagnostic problems...
  11. doi Labeling of multiple cell markers and mRNA using automated apparatus
    Jennifer C Paterson
    Leukaemia Research Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK
    Appl Immunohistochem Mol Morphol 16:371-81. 2008
    ..Finally, automated labeling could also be performed on peripheral blood and bone marrow smears, opening the possibility of using this procedure in the analysis of hematologic/cytology samples...
  12. ncbi Transmembrane adaptor molecules: a new category of lymphoid-cell markers
    Sara Tedoldi
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom
    Blood 107:213-21. 2006
    ..These molecules represent a potentially important addition to the panel of immunophenotypic markers detectable in routine biopsies that can be used in hematopathologic studies...
  13. ncbi Expression pattern of FCRL (FREB, FcRX) in normal and neoplastic human B cells
    Noraidah Masir
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 127:335-43. 2004
    ..FCRL may therefore represent a novel marker for normal B cells (e.g. splenic marginal zone cells) and may also be useful as a potential marker of B-cell neoplasms...
  14. pmc Can cytoplasmic nucleophosmin be detected by immunocytochemical staining of cell smears in acute myeloid leukemia?
    Goran Mattsson
    1Leukaemia Research Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Haematologica 95:670-3. 2010
    ..Due to the high false positive and negative rates for cNPM in cell smears, this method should not be used as a surrogate for NPM1 mutations in AML...
  15. doi Focal adhesion kinase (FAK) expression in normal and neoplastic lymphoid tissues
    Sermin Ozkal
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK
    Pathol Res Pract 205:781-8. 2009
    ....
  16. pmc The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation
    Teresa Marafioti
    Leukaemia Research Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Haematologica 95:432-9. 2010
    ..Recently, CXCL13, PD-1 and SAP were described as useful markers for T(FH) cells and angioimmunoblastic T-cell lymphoma but also reported in some peripheral T-cell lymphomas, not otherwise specified...
  17. ncbi Cancer-associated carbohydrate identification in Hodgkin's lymphoma by carbohydrate array profiling
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, UK
    Int J Cancer 118:3161-6. 2006
    ..271). We suggest that this technique could provide a powerful tool for identifying novel carbohydrates in other cancers...
  18. pmc Detection of genetic alterations by immunoFISH analysis of whole cells extracted from routine biopsy material
    Goran Mattsson
    Haematology Department, Level 4, John Radcliffe Hospital, Oxford OX3 9DU, UK
    J Mol Diagn 9:479-89. 2007
    ..This procedure represents a novel methodology, which in some settings offers clear advantages over analysis of tissue sections...
  19. ncbi The FOXP1 transcription factor is expressed in the majority of follicular lymphomas but is rarely expressed in classical and lymphocyte predominant Hodgkin's lymphoma
    Philip Brown
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Level 5, Room 5501, Oxford, OX3 9DU, UK
    J Mol Histol 36:249-56. 2005
    ..The heterogeneity of FOXP1 expression in germinal centre-derived lymphomas, may have more to do with the transforming events underlying these distinct types of lymphoma than with their common origin...
  20. pmc Follicular lymphoma with trisomy 18 exhibiting loss of BCL-2 expression on transformation to a large cell lymphoma
    Noraidah Masir
    Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford, UK
    J Clin Pathol 60:1061-4. 2007
  21. doi Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes
    Andrea Pellagatti
    LRF Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 146:86-90. 2009
    ..Downregulation of LEF1 mRNA was reflected at the protein level. Immunostaining for CD34/LEF1 may represent a marker of advanced MDS. LEF1 may play a role in the defective maturation of myeloid progenitors in MDS...
  22. ncbi MicroRNA expression distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Int J Cancer 121:1156-61. 2007
    ..001), we suggest that microRNAs could be clinically useful molecular markers for DLBCL as well as other cancers...
  23. ncbi Expression of two markers of germinal center T cells (SAP and PD-1) in angioimmunoblastic T-cell lymphoma
    Giovanna Roncador
    Monoclonal Antibodies Unit, Biotechnology Program, Spanish National Cancer Centre, Madrid, Spain
    Haematologica 92:1059-66. 2007
    ....
  24. doi Detection of LIM domain only 2 (LMO2) in normal human tissues and haematopoietic and non-haematopoietic tumours using a newly developed rabbit monoclonal antibody
    Claudio Agostinelli
    Section of Haematopathology, Department of Haematology and Oncological Sciences Seràgnoli, S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Histopathology 61:33-46. 2012
    ..We describe a new rabbit monoclonal antibody, raised against a fixation-resistant epitope of the transcription regulator LIM domain only 2 (LMO2)...
  25. pmc Immune phenotype predicts risk for posttransplantation squamous cell carcinoma
    Robert P Carroll
    Transplantation Research Immunology Group, Nuffield Department of Surgery, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, United Kingdom
    J Am Soc Nephrol 21:713-22. 2010
    ..In summary, monitoring components of the immune system can predict development of cutaneous SCC among KTRs...
  26. pmc B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling
    Diana Cozma
    Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6051, USA
    J Clin Invest 117:2602-10. 2007
    ..Thus, stimulation of neoplastic growth by Pax5 occurs through BCR and is sensitive to genetic and pharmacological inhibitors of this pathway...
  27. ncbi Frequent epigenetic silencing of protocadherin 10 by methylation in multiple haematologic malignancies
    Jianming Ying
    Cancer Epigenetics Laboratory, Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong
    Br J Haematol 136:829-32. 2007
    ..Methylation was further detected in 14% of Hodgkin lymphoma sera. Thus, PCDH10 methylation is frequently involved in lymphomagenesis and could serve as a tumour-specific biomarker...
  28. ncbi PRDM1/BLIMP-1 expression in multiple B and T-cell lymphoma
    Jose Francisco Garcia
    Monoclonal Antibodies Unit, Biotechnology Program, Spanish National Cancer Centre CNIO, Madrid, Spain
    Haematologica 91:467-74. 2006
    ..The positive regulatory domain I (PRDM1) protein or BLIMP-1, belonging to the PRDM gene family of transcriptional repressors, is a key regulator of terminal differentiation in B-lymphocytes and is critical for plasma cell differentiation...
  29. ncbi Immunoglobulin gene rearrangement analysis in composite hodgkin disease and large B-cell lymphoma: evidence for receptor revision of immunoglobulin heavy chain variable region genes in Hodgkin-Reed-Sternberg cells?
    Cristiana Bellan
    Institute of Pathologic Anatomy and Histopathology, University of Siena, Italy
    Diagn Mol Pathol 11:2-8. 2002
    ....
  30. pmc Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation
    Yasodha Natkunam
    Department of Pathology, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305, USA
    Blood 105:3979-86. 2005
    ..The restricted expression and GC specificity of HGAL protein suggest that it may have an important role in the diagnosis of specific lymphomas, and, potentially in the identification of subtypes associated with different prognoses...
  31. pmc Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins
    Stefano A Pileri
    Istituto di Ematologia e Oncologia Medica, L e A Seràgnoli Unità Cliniche e di Anatomia Patologica, Universita di Bologna, Bologna, Italy
    Am J Pathol 162:243-53. 2003
    ..However, it differs from other aggressive B-cell lymphomas in that it shows defective immunoglobulin production despite the expression of OCT-2, BOB.1, and PU.1 transcription factors and the lack of IgV(H) gene crippling mutations...
  32. ncbi Aberrant somatic hypermutation in tumor cells of nodular-lymphocyte-predominant and classic Hodgkin lymphoma
    Arcangelo Liso
    Institute of Hematology, University of Perugia, Policlinico, Monteluce, 06122 Perugia, Italy
    Blood 108:1013-20. 2006
    ..Our finding that NLPHL and cHL are targeted by aberrant SHM, as is DLBCL, suggests that these lymphomas may share common molecular pathogenetic events...
  33. ncbi Histopathology of B-cell chronic lymphocytic leukemia
    Stefano A Pileri
    Unit of Haematopathology, Institute of Haematology and Clinical Oncology L and A Seràgnoli, Bologna University, Via Massarenti 9, 40138 Bologna, Italy
    Hematol Oncol Clin North Am 18:807-26, viii. 2004
    ..The relevance of the examination of trephines and surgical specimens is outlined with special reference to the identification of risk factors in individual patients...
  34. ncbi Diffuse large B-cell lymphoma (DLBCL), anaplastic variant. report on a problematic case primarily arising in the stomach
    Stefano Aldo Pileri
    Pathologic Anatomy, Clinical and Pathology Lymphoma Units, Institute of Haematology and Clinical Oncology L and A Seràgnoli, Bologna University, Italy
    Haematologica 87:ECR40. 2002
  35. ncbi ZAP-70 expression in normal pro/pre B cells, mature B cells, and in B-cell acute lymphoblastic leukemia
    Marta Crespo
    Department of Hematology, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    Clin Cancer Res 12:726-34. 2006
    ..The purpose was to investigate the presence of ZAP-70 in normal pro/pre B cells and mature B cells and in tumoral cells from B-acute lymphoblastic leukemias (B-ALL)...