Research Topics
| S E ManleySummaryAffiliation: University Hospital Birmingham Country: UK Publications
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Detail Information
Publications
Standardization of glycated haemoglobinSally M Marshall
Ann Clin Biochem 39:78-9. 2002
Validation of an algorithm combining haemoglobin A(1c) and fasting plasma glucose for diagnosis of diabetes mellitus in UK and Australian populationsS E Manley
Clinical Biochemistry, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK
Diabet Med 26:115-21. 2009..To determine whether glycated haemoglobin (HbA(1c)) can be used in combination with fasting plasma glucose (FPG) for the diagnosis of diabetes in patients with impaired fasting glucose (IFG) and in a broader spectrum of patients...
Preanalytical, analytical, and computational factors affect homeostasis model assessment estimatesSusan E Manley
Clinical Biochemistry, University Hospital Birmingham NHS Foundation Trust, University of Birmingham, Birmingham, UK
Diabetes Care 31:1877-83. 2008..We investigated how beta-cell function and insulin sensitivity or resistance are affected by the type of blood sample collected or choice of insulin assay and homeostatis model assessment (HOMA) calculator (http://www.dtu.ox.ac.uk)...
Estimated average glucose derived from HbA1c eAG: report from European Association for the Study of Diabetes (EASD), Amsterdam 2007S E Manley
Clinical Biochemistry, University Hospital Birmingham NHS Trust, Brimingham, UK
Diabet Med 25:126-8. 2008
Comparison of 11 human insulin assays: implications for clinical investigation and researchSusan E Manley
Department of Clinical Biochemistry, University Hospital Birmingham NHS Foundation Trust, University of Birmingham, Birmingham, United Kingdom
Clin Chem 53:922-32. 2007..The American Diabetes Association task force on standardization of insulin assays in 1996 showed wide variation in assay bias. Newer assays are specific for insulin, with several now available on automated immunoassay analyzers...
Calibration of HbA1c and its measurement in the presence of variant haemoglobins: report on questionnaire to manufacturersS E Manley
Department of Clinical Biochemistry, University Hospital Birmingham NHS Trust, Selly Oak Hospital, Raddlebarn Road, Birmingham, B29 6JD, UK
Ann Clin Biochem 43:135-45. 2006....
Introduction of IFCC reference method for calibration of HbA: implications for clinical careS Manley
Clinical Biochemistry, University Hospital Birmingham NHS Trust, Birmingham, UK
Diabet Med 21:673-6. 2004..The UK HbA(1c) Standardization Committee was set up to hold "a watching brief " on HbA(1c) especially with relation to reporting of HbA(1c) in other countries...
Haemoglobin A1c--a marker for complications of type 2 diabetes: the experience from the UK Prospective Diabetes Study (UKPDS)Susan Manley
Department of Clinical Biochemistry, University Hospital Birmingham, Birmingham, UK
Clin Chem Lab Med 41:1182-90. 2003..The UKPDS risk engine derived from the UKPDS database calculates coronary heart disease risk using HbA1c as a continuous variable and could now replace the Framingham equations for patients with type 2 diabetes...
Randomized dose ranging study of the reduction of fasting and postprandial glucose in type 2 diabetes by nateglinide (A-4166)F M Gribble
Department of Clinical Biochemistry, Addenbrooke's Hospital, Cambridge, UK
Diabetes Care 24:1221-5. 2001..Administered 5 min before a meal, nateglinide reduced the postprandial glucose excursion by 64%. With its rapid onset and short duration of action, nateglinide is a promising oral prandial therapy in type 2 diabetes...
UKPDS 60: risk of stroke in type 2 diabetes estimated by the UK Prospective Diabetes Study risk engineViti Kothari
Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Radcliffe Infirmary, Oxford, United Kingdom
Stroke 33:1776-81. 2002..CONCLUSIONS: This model forecasts the absolute risk of a first stroke in people with type 2 diabetes using variables readily available in routine clinical practice...
