Giovanna R Mallucci
Affiliation: University College London
- Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant miceMohammed A Nassar
Molecular Nociception Group, Department of Biology, University College London WC1E 6BT, UK
Mol Pain 2:33. 2006..Furthermore, ectopic discharges from damaged nerves were unaffected by the absence of Nav1.3 in global knock-out mice. Our data demonstrate that Nav1.3 is neither necessary nor sufficient for the development of nerve-injury related pain...
- Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected miceGiovanna R Mallucci
MRC Prion Unit, Department of Neurodegenerative Disease, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
Neuron 53:325-35. 2007..These data suggest that early intervention in human prion disease may lead to recovery of cognitive and behavioral symptoms...
- Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion diseaseMelanie D White
Department of Neurodegenerative Disease, Medical Research Council, Prion Unit Institute of Neurology, University College London, London, United Kingdom
Proc Natl Acad Sci U S A 105:10238-43. 2008....