Joanne E Mallinson

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents
    Joanne E Mallinson
    MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, School of Biomedical Sciences, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    J Physiol 590:6389-402. 2012
  2. pmc Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy
    Joanne E Mallinson
    Centre for Integrated Systems Biology and Medicine, School of Biomedical Sciences, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    J Physiol 587:219-30. 2009
  3. doi request reprint Obesity Appears to Be Associated With Altered Muscle Protein Synthetic and Breakdown Responses to Increased Nutrient Delivery in Older Men, but Not Reduced Muscle Mass or Contractile Function
    Andrew J Murton
    MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham Medical School, Queen s Medical Centre, Nottingham, U K
    Diabetes 64:3160-71. 2015
  4. pmc Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression
    Joanne E Mallinson
    MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Nottingham, Nottingham, NG7 2UH, UK
    J Physiol 593:1239-57. 2015
  5. pmc Fetal exposure to a maternal low-protein diet during mid-gestation results in muscle-specific effects on fibre type composition in young rats
    Joanne E Mallinson
    Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Sutton Bonington, Loughborough, LE12 5RD, UK
    Br J Nutr 98:292-9. 2007

Detail Information

Publications5

  1. pmc Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents
    Joanne E Mallinson
    MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, School of Biomedical Sciences, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    J Physiol 590:6389-402. 2012
    ..PDC activation abolished statin myopathy in rodent skeletal muscle, which occurred at least in part via inhibition of FOXO-mediated transcription of genes regulating muscle CHO utilisation and protein breakdown...
  2. pmc Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy
    Joanne E Mallinson
    Centre for Integrated Systems Biology and Medicine, School of Biomedical Sciences, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    J Physiol 587:219-30. 2009
    ..These changes occurred in the main before evidence of extensive myopathy or a decline in the muscle protein to DNA ratio...
  3. doi request reprint Obesity Appears to Be Associated With Altered Muscle Protein Synthetic and Breakdown Responses to Increased Nutrient Delivery in Older Men, but Not Reduced Muscle Mass or Contractile Function
    Andrew J Murton
    MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham Medical School, Queen s Medical Centre, Nottingham, U K
    Diabetes 64:3160-71. 2015
    ..This does not, however, appear to be associated with lower leg lean mass or strength. ..
  4. pmc Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression
    Joanne E Mallinson
    MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Nottingham, Nottingham, NG7 2UH, UK
    J Physiol 593:1239-57. 2015
    ....
  5. pmc Fetal exposure to a maternal low-protein diet during mid-gestation results in muscle-specific effects on fibre type composition in young rats
    Joanne E Mallinson
    Division of Nutritional Sciences, School of Biosciences, University of Nottingham, Sutton Bonington, Loughborough, LE12 5RD, UK
    Br J Nutr 98:292-9. 2007
    ..In conclusion, a maternal low-protein diet mainly during mid-pregnancy reduced muscle fibre number and density in 4-week-old rats, but there were muscle-specific differences in the fibre types affected...