Affiliation: University of Newcastle
- Review: Mitochondria and disease progression in multiple sclerosisD Mahad
The Mitochondrial Research Group, University of Newcastle upon Tyne, Newcastle, UK
Neuropathol Appl Neurobiol 34:577-89. 2008..Mitochondria are a potential therapeutic target in MS...
- Mitochondria as crucial players in demyelinated axons: lessons from neuropathology and experimental demyelinationGraham R Campbell
Mitochondrial Research Group, Institute for Ageing and Health, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
Autoimmune Dis 2011:262847. 2011....
- Mitochondrial DNA deletions and neurodegeneration in multiple sclerosisGraham R Campbell
Institute of Ageing and Health, Mitochondrial Research Group, Newcastle University, Newcastle upon Tyne, UK
Ann Neurol 69:481-92. 2011..We explored mitochondrial respiratory chain activity and mtDNA deletions in single neurons from secondary progressive MS (SPMS) cases...
- Loss of myelin-associated glycoprotein in kearns-sayre syndromeNichola Z Lax
Mitochondrial Research Group, Institute for Aging and Health, Newcastle University, Framlington Place, Newcastle upon Tyne, United Kingdom
Arch Neurol 69:490-9. 2012..To explore myelin components and mitochondrial changes within the central nervous system in patients with well-characterized mitochondrial disorders due to nuclear DNA or mitochondrial DNA (mtDNA) mutations...
- Mitochondrial changes within axons in multiple sclerosisDon J Mahad
Mitochondrial Research Group, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
Brain 132:1161-74. 2009..Our findings have important implications for both axonal degeneration and dysfunction during the progressive stage of multiple sclerosis...