Stuart A MacNeill
Affiliation: University of St Andrews
- Composition and dynamics of the eukaryotic replisome: a brief overviewStuart Macneill
Biomedical Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife, KY16 9ST, UK
Subcell Biochem 62:1-17. 2012..Here I present a brief overview of current knowledge of the composition of the replisome and the dynamic molecular events that underlie chromosomal DNA replication in eukaryotic cells...
- Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesisJavier Sanchez Garcia
Wellcome Trust Centre for Cell Biology, University of Edinburgh, King s Buildings, Mayfield Road, Edinburgh, EH9 3JR, UK
BMC Mol Biol 10:82. 2009..Human Pol delta comprises the same four subunits, and the crystal structure was recently reported of a complex of human p50 and the N-terminal domain of p66, the human orthologues of Cdc1 and Cdc27, respectively...
- Structure and function of the GINS complex, a key component of the eukaryotic replisomeStuart A MacNeill
Biomedical Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK
Biochem J 425:489-500. 2010....
- Protein-protein interactions in the archaeal core replisomeStuart A MacNeill
Medical and Biological Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9TF, UK
Biochem Soc Trans 39:163-8. 2011..The present review summarizes current knowledge of how the core components of the archaeal chromosome replication apparatus interact with one another to perform their essential functions...
- Identification of essential and non-essential single-stranded DNA-binding proteins in a model archaeal organismAgnieszka Skowyra
School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9TF, UK
Nucleic Acids Res 40:1077-90. 2012..Taken together, our results offer important insights into archaeal SSB function and establish the haloarchaea as a valuable model for further studies...
- The archaeo-eukaryotic GINS proteins and the archaeal primase catalytic subunit PriS share a common domainAgnieszka Swiatek
Centre for Biomolecular Sciences, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK
Biol Direct 5:17. 2010..The presence of a shared domain in archaeal PriS and GINS proteins, the genes for which are often found adjacent on the chromosome, suggests simple mechanisms for the evolution of these proteins...