Isla S Mackenzie

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. pmc Cardiovascular safety of lumiracoxib: a meta-analysis of randomised controlled trials in patients with osteoarthritis
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO and Hypertension Research Centre HRC, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Eur J Clin Pharmacol 69:133-41. 2013
  2. pmc Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study
    Isla S Mackenzie
    Medicines Monitoring Unit, University of Dundee, Dundee DD1 9SY, UK
    BMJ 345:e4447. 2012
  3. pmc Cluster randomized trials of prescription medicines or prescribing policy: public and general practitioner opinions in Scotland
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Br J Clin Pharmacol 74:354-61. 2012
  4. pmc Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self-reporting of serious adverse events and pregnancy outcomes
    Isla S Mackenzie
    Medicines Monitoring Unit, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Br J Clin Pharmacol 73:801-11. 2012
  5. doi request reprint Molecular and clinical investigations in patients with low-renin hypertension
    Isla S Mackenzie
    Hypertension Research Centre, Ninewells Hospital, University of Dundee, Level 7, Dundee, DD1 9SY, UK
    Clin Exp Nephrol 13:1-8. 2009
  6. doi request reprint Managing security and privacy concerns over data storage in healthcare research
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Pharmacoepidemiol Drug Saf 20:885-93. 2011
  7. pmc Promoting public awareness of randomised clinical trials using the media: the 'Get Randomised' campaign
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee and Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Br J Clin Pharmacol 69:128-35. 2010
  8. doi request reprint Treatment of osteoarthritis in hypertensive patients
    Isla S Mackenzie
    University of Dundee, Ninewells Hospital, Hypertension Research Centre and Medicines Monitoring Unit, Level 7, Dundee DD1 9SY, UK
    Expert Opin Pharmacother 11:393-403. 2010
  9. pmc Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis
    Isla S Mackenzie
    Hypertension Research Centre, Division of Medicine and Therapeutics, University of Dundee, Dundee DD1 9SY, UK
    Arthritis Res Ther 10:S3. 2008
  10. doi request reprint Association between cardiovascular events and sodium-containing effervescent, dispersible, and soluble drugs: nested case-control study
    Jacob George
    Division of Medical Science, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    BMJ 347:f6954. 2013

Detail Information

Publications12

  1. pmc Cardiovascular safety of lumiracoxib: a meta-analysis of randomised controlled trials in patients with osteoarthritis
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO and Hypertension Research Centre HRC, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Eur J Clin Pharmacol 69:133-41. 2013
    ..To re-evaluate the cardiovascular risk of lumiracoxib compared with other non-steroidal anti-inflammatory drugs (NSAIDs) or placebo in patients with osteoarthritis...
  2. pmc Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study
    Isla S Mackenzie
    Medicines Monitoring Unit, University of Dundee, Dundee DD1 9SY, UK
    BMJ 345:e4447. 2012
    ..To investigate whether exposure to spironolactone treatment affects the risk of incident breast cancer in women over 55 years of age...
  3. pmc Cluster randomized trials of prescription medicines or prescribing policy: public and general practitioner opinions in Scotland
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Br J Clin Pharmacol 74:354-61. 2012
    ..To understand public and general practitioner (GP) opinion on the acceptability of randomized policy design (RPD) studies (cluster randomized trials) of prescription medicines in Scotland...
  4. pmc Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self-reporting of serious adverse events and pregnancy outcomes
    Isla S Mackenzie
    Medicines Monitoring Unit, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Br J Clin Pharmacol 73:801-11. 2012
    ....
  5. doi request reprint Molecular and clinical investigations in patients with low-renin hypertension
    Isla S Mackenzie
    Hypertension Research Centre, Ninewells Hospital, University of Dundee, Level 7, Dundee, DD1 9SY, UK
    Clin Exp Nephrol 13:1-8. 2009
    ..The importance of investigation, factors determining renin and aldosterone levels, and drug therapies in low-renin hypertension are reviewed...
  6. doi request reprint Managing security and privacy concerns over data storage in healthcare research
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Pharmacoepidemiol Drug Saf 20:885-93. 2011
    ..We discuss holistic measures, involving both information technology and people, taken to improve the security and privacy of data storage...
  7. pmc Promoting public awareness of randomised clinical trials using the media: the 'Get Randomised' campaign
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee and Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Br J Clin Pharmacol 69:128-35. 2010
    ..8, 3.1%; P= 0.92]. CONCLUSIONS It is possible to raise public awareness of clinical research using the media, but further efforts may be required to influence individuals' decisions to take part in clinical research...
  8. doi request reprint Treatment of osteoarthritis in hypertensive patients
    Isla S Mackenzie
    University of Dundee, Ninewells Hospital, Hypertension Research Centre and Medicines Monitoring Unit, Level 7, Dundee DD1 9SY, UK
    Expert Opin Pharmacother 11:393-403. 2010
    ..NSAIDs may also increase cardiovascular risk due to mechanisms other than by raising blood pressure...
  9. pmc Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis
    Isla S Mackenzie
    Hypertension Research Centre, Division of Medicine and Therapeutics, University of Dundee, Dundee DD1 9SY, UK
    Arthritis Res Ther 10:S3. 2008
    ..Further studies of the effects of CINODs in humans are required, but these agents represent a potential exciting advance in the management of osteoarthritis...
  10. doi request reprint Association between cardiovascular events and sodium-containing effervescent, dispersible, and soluble drugs: nested case-control study
    Jacob George
    Division of Medical Science, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    BMJ 347:f6954. 2013
    ..To determine whether patients taking formulations of drugs that contain sodium have a higher incidence of cardiovascular events compared with patients on non-sodium formulations of the same drugs...
  11. pmc Pioglitazone and bladder cancer: a propensity score matched cohort study
    Li Wei
    Medicines Monitoring Unit, Division of Medicine and Therapeutics, Ninewells Hospital and Medical School, Dundee, Scotland, UK
    Br J Clin Pharmacol 75:254-9. 2013
    ..To examine whether exposure to pioglitazone use is associated with increased incidence of bladder cancer in patients with type 2 diabetes mellitus...
  12. pmc Impact of allopurinol use on urate concentration and cardiovascular outcome
    Li Wei
    Medicines Monitoring Unit MEMO, Division of Medical Sciences, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Br J Clin Pharmacol 71:600-7. 2011
    ..To characterize patients with urate measurements by urate-lowering therapy (ULT) use and to study the impact of allopurinol treatment on cardiovascular and mortality outcomes...