Isla S Mackenzie

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. pmc Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice Research Database
    I S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    J Neurol Neurosurg Psychiatry 85:76-84. 2014
  2. pmc Cardiovascular safety of lumiracoxib: a meta-analysis of randomised controlled trials in patients with osteoarthritis
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO and Hypertension Research Centre HRC, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Eur J Clin Pharmacol 69:133-41. 2013
  3. pmc Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study
    Isla S Mackenzie
    Medicines Monitoring Unit, University of Dundee, Dundee DD1 9SY, UK
    BMJ 345:e4447. 2012
  4. pmc Cluster randomized trials of prescription medicines or prescribing policy: public and general practitioner opinions in Scotland
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Br J Clin Pharmacol 74:354-61. 2012
  5. pmc Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self-reporting of serious adverse events and pregnancy outcomes
    Isla S Mackenzie
    Medicines Monitoring Unit, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Br J Clin Pharmacol 73:801-11. 2012
  6. doi request reprint Molecular and clinical investigations in patients with low-renin hypertension
    Isla S Mackenzie
    Hypertension Research Centre, Ninewells Hospital, University of Dundee, Level 7, Dundee, DD1 9SY, UK
    Clin Exp Nephrol 13:1-8. 2009
  7. doi request reprint Managing security and privacy concerns over data storage in healthcare research
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Pharmacoepidemiol Drug Saf 20:885-93. 2011
  8. pmc Promoting public awareness of randomised clinical trials using the media: the 'Get Randomised' campaign
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee and Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Br J Clin Pharmacol 69:128-35. 2010
  9. ncbi request reprint Treatment of osteoarthritis in hypertensive patients
    Isla S Mackenzie
    University of Dundee, Ninewells Hospital, Hypertension Research Centre and Medicines Monitoring Unit, Level 7, Dundee DD1 9SY, UK
    Expert Opin Pharmacother 11:393-403. 2010
  10. pmc Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis
    Isla S Mackenzie
    Hypertension Research Centre, Division of Medicine and Therapeutics, University of Dundee, Dundee DD1 9SY, UK
    Arthritis Res Ther 10:S3. 2008

Collaborators

Detail Information

Publications17

  1. pmc Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice Research Database
    I S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    J Neurol Neurosurg Psychiatry 85:76-84. 2014
    ....
  2. pmc Cardiovascular safety of lumiracoxib: a meta-analysis of randomised controlled trials in patients with osteoarthritis
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO and Hypertension Research Centre HRC, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Eur J Clin Pharmacol 69:133-41. 2013
    ..To re-evaluate the cardiovascular risk of lumiracoxib compared with other non-steroidal anti-inflammatory drugs (NSAIDs) or placebo in patients with osteoarthritis...
  3. pmc Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study
    Isla S Mackenzie
    Medicines Monitoring Unit, University of Dundee, Dundee DD1 9SY, UK
    BMJ 345:e4447. 2012
    ..To investigate whether exposure to spironolactone treatment affects the risk of incident breast cancer in women over 55 years of age...
  4. pmc Cluster randomized trials of prescription medicines or prescribing policy: public and general practitioner opinions in Scotland
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Br J Clin Pharmacol 74:354-61. 2012
    ..To understand public and general practitioner (GP) opinion on the acceptability of randomized policy design (RPD) studies (cluster randomized trials) of prescription medicines in Scotland...
  5. pmc Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self-reporting of serious adverse events and pregnancy outcomes
    Isla S Mackenzie
    Medicines Monitoring Unit, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Br J Clin Pharmacol 73:801-11. 2012
    ....
  6. doi request reprint Molecular and clinical investigations in patients with low-renin hypertension
    Isla S Mackenzie
    Hypertension Research Centre, Ninewells Hospital, University of Dundee, Level 7, Dundee, DD1 9SY, UK
    Clin Exp Nephrol 13:1-8. 2009
    ..The importance of investigation, factors determining renin and aldosterone levels, and drug therapies in low-renin hypertension are reviewed...
  7. doi request reprint Managing security and privacy concerns over data storage in healthcare research
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee, UK
    Pharmacoepidemiol Drug Saf 20:885-93. 2011
    ..We discuss holistic measures, involving both information technology and people, taken to improve the security and privacy of data storage...
  8. pmc Promoting public awareness of randomised clinical trials using the media: the 'Get Randomised' campaign
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee and Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Br J Clin Pharmacol 69:128-35. 2010
    ..8, 3.1%; P= 0.92]. CONCLUSIONS It is possible to raise public awareness of clinical research using the media, but further efforts may be required to influence individuals' decisions to take part in clinical research...
  9. ncbi request reprint Treatment of osteoarthritis in hypertensive patients
    Isla S Mackenzie
    University of Dundee, Ninewells Hospital, Hypertension Research Centre and Medicines Monitoring Unit, Level 7, Dundee DD1 9SY, UK
    Expert Opin Pharmacother 11:393-403. 2010
    ..NSAIDs may also increase cardiovascular risk due to mechanisms other than by raising blood pressure...
  10. pmc Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis
    Isla S Mackenzie
    Hypertension Research Centre, Division of Medicine and Therapeutics, University of Dundee, Dundee DD1 9SY, UK
    Arthritis Res Ther 10:S3. 2008
    ..Further studies of the effects of CINODs in humans are required, but these agents represent a potential exciting advance in the management of osteoarthritis...
  11. pmc Association between cardiovascular events and sodium-containing effervescent, dispersible, and soluble drugs: nested case-control study
    Jacob George
    Division of Medical Science, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    BMJ 347:f6954. 2013
    ..To determine whether patients taking formulations of drugs that contain sodium have a higher incidence of cardiovascular events compared with patients on non-sodium formulations of the same drugs...
  12. pmc Impact of allopurinol use on urate concentration and cardiovascular outcome
    Li Wei
    Medicines Monitoring Unit MEMO, Division of Medical Sciences, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Br J Clin Pharmacol 71:600-7. 2011
    ..To characterize patients with urate measurements by urate-lowering therapy (ULT) use and to study the impact of allopurinol treatment on cardiovascular and mortality outcomes...
  13. ncbi request reprint Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial
    Miles D Witham
    Ageing and Health, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, United Kingdom
    Hypertension 63:706-12. 2014
    ..04). There was no significant change in cholesterol or glucose levels. Thus, 6 months of intermittent, high-dose oral vitamin D3 did not reduce blood pressure or left ventricular mass in patients with resistant hypertension. ..
  14. pmc Pioglitazone and bladder cancer: a propensity score matched cohort study
    Li Wei
    Medicines Monitoring Unit, Division of Medicine and Therapeutics, Ninewells Hospital and Medical School, Dundee, Scotland, UK
    Br J Clin Pharmacol 75:254-9. 2013
    ..To examine whether exposure to pioglitazone use is associated with increased incidence of bladder cancer in patients with type 2 diabetes mellitus...
  15. ncbi request reprint Effectiveness of newspaper advertising for patient recruitment into a clinical trial
    Adrian Hapca
    Medicines Monitoring Unit, University of Dundee, Ninewells Hospital, Dundee, DD1 9SY, UK
    Br J Clin Pharmacol 77:1064-72. 2014
    ..Celecoxib Outcome Trial (SCOT), a clinical trial investigating the cardiovascular safety of non-steroidal anti-inflammatory drugs in patients with osteoarthritis or rheumatoid arthritis...
  16. ncbi request reprint Up-titration of allopurinol in patients with gout
    Claudine G Jennings
    Medicines Monitoring Unit MEMO, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK Electronic address
    Semin Arthritis Rheum 44:25-30. 2014
    ..The objective of this analysis was to review the efficacy and tolerability of allopurinol up-titration in achieving the EULAR target levels...
  17. pmc Renal artery stenosis-when to screen, what to stent?
    Claudine G Jennings
    Medicines Monitoring Unit and Hypertension Research Centre, Ninewells Hospital and University of Dundee, Dundee, DD1 9SY, UK
    Curr Atheroscler Rep 16:416. 2014
    ..The potential benefits in terms of improving hard cardiovascular outcomes may outweigh the risks of intervention in this group, and further research is needed. ..