F M MacKenzie

Summary

Affiliation: University of Aberdeen
Country: UK

Publications

  1. ncbi request reprint Report of the Consensus Conference on Antibiotic Resistance; Prevention and Control (ARPAC)
    F M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Clin Microbiol Infect 11:938-54. 2005
  2. ncbi request reprint The post-exposure response of Enterobacteriaceae to ceftibuten
    F M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, UK
    J Antimicrob Chemother 43:71-7. 1999
  3. ncbi request reprint Relationship between the number of different antibiotics used and the total use of antibiotics in European hospitals
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary Aberdeen, Scotland, UK
    J Antimicrob Chemother 58:657-60. 2006
  4. ncbi request reprint Reassessment of the cefaclor breakpoint for Streptococcus pneumoniae
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, Scotland, UK
    Int J Antimicrob Agents 23:337-42. 2004
  5. ncbi request reprint Antimicrobial susceptibility testing in European hospitals: report from the ARPAC study
    F M MacKenzie
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Clin Microbiol Infect 12:1185-92. 2006
  6. ncbi request reprint Antimicrobial drug use and infection control practices associated with the prevalence of methicillin-resistant Staphylococcus aureus in European hospitals
    F M MacKenzie
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Clin Microbiol Infect 13:269-76. 2007
  7. ncbi request reprint Comparison of screening methods for TEM- and SHV-derived extended-spectrum beta-lactamase detection
    F M MacKenzie
    Aberdeen Royal Infirmary, UK
    Clin Microbiol Infect 8:715-24. 2002
  8. ncbi request reprint Identification and characterization of teicoplanin-intermediate Staphylococcus aureus blood culture isolates in NE Scotland
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    J Antimicrob Chemother 50:689-97. 2002
  9. ncbi request reprint Calculation of composite recovery time: a new pharmacodynamic parameter
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    J Antimicrob Chemother 50:281-4. 2002
  10. ncbi request reprint The role of microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    J Hosp Infect 65:73-81. 2007

Detail Information

Publications22

  1. ncbi request reprint Report of the Consensus Conference on Antibiotic Resistance; Prevention and Control (ARPAC)
    F M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Clin Microbiol Infect 11:938-54. 2005
    ..The conference delivered a set of high-priority recommendations likely to have a significant impact on antimicrobial resistance. This report summarises these recommendations...
  2. ncbi request reprint The post-exposure response of Enterobacteriaceae to ceftibuten
    F M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, UK
    J Antimicrob Chemother 43:71-7. 1999
    ..The results of the PA-SME studies, which may be the most clinically relevant pharmacodynamic parameter, confirm the appropriateness of the current once- or twice-daily dosing schedules despite the lack of PAE...
  3. ncbi request reprint Relationship between the number of different antibiotics used and the total use of antibiotics in European hospitals
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary Aberdeen, Scotland, UK
    J Antimicrob Chemother 58:657-60. 2006
    ..The aim of this study was to establish whether there was a relationship between the number of antibacterial agents used and total antibiotic use in European hospitals...
  4. ncbi request reprint Reassessment of the cefaclor breakpoint for Streptococcus pneumoniae
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, Scotland, UK
    Int J Antimicrob Agents 23:337-42. 2004
    ..00058) there was no statistical differences between the bacteriostatic MICs (P = 0.259). Bacteriostatic MIC determination established that cefaclor and cefuroxime are equally active against pneumococci...
  5. ncbi request reprint Antimicrobial susceptibility testing in European hospitals: report from the ARPAC study
    F M MacKenzie
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Clin Microbiol Infect 12:1185-92. 2006
    ..The majority of respondents stated that they followed CLSI guidelines, but a high proportion had modified the CLSI methods for detecting MRSA and VRE, which may compromise clinical management and antimicrobial resistance surveillance...
  6. ncbi request reprint Antimicrobial drug use and infection control practices associated with the prevalence of methicillin-resistant Staphylococcus aureus in European hospitals
    F M MacKenzie
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Clin Microbiol Infect 13:269-76. 2007
    ..Overall, this study highlighted significant associations between MRSA prevalence, antimicrobial use and various key infection control parameters, all of which showed significant individual variations according to geographical region...
  7. ncbi request reprint Comparison of screening methods for TEM- and SHV-derived extended-spectrum beta-lactamase detection
    F M MacKenzie
    Aberdeen Royal Infirmary, UK
    Clin Microbiol Infect 8:715-24. 2002
    ..To compare common extended-spectrum beta-lactamase (ESBL) screening methods and beta-lactams for their ability to detect TEM- and SHV-related ESBL enzymes...
  8. ncbi request reprint Identification and characterization of teicoplanin-intermediate Staphylococcus aureus blood culture isolates in NE Scotland
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    J Antimicrob Chemother 50:689-97. 2002
    ..Both MRSA and MSSA with reduced teicoplanin susceptibility may remain vancomycin sensitive by NCCLS and BSAC criteria and it is important to screen clinical isolates of MRSA and MSSA for reduced susceptibility to both agents...
  9. ncbi request reprint Calculation of composite recovery time: a new pharmacodynamic parameter
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    J Antimicrob Chemother 50:281-4. 2002
    ..influenzae isolate, 1 mg/L for staphylococci and 0.5 mg/L for Enterobacteriaceae. Calculated pharmacodynamic breakpoints were very similar to traditional published MIC breakpoints...
  10. ncbi request reprint The role of microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals
    Fiona M MacKenzie
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    J Hosp Infect 65:73-81. 2007
    ..There was also no evidence that pharmacy services reduced the amount of antibiotics prescribed...
  11. ncbi request reprint Reassessment of cefaclor breakpoints for Haemophilus influenzae
    F M MacKenzie
    Medical Microbiology Department, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZN Scotland, UK
    J Chemother 16:329-33. 2004
    ..8 mg/L for cefuroxime. Cefaclor MICs by NCCLS methodology were overestimated due to chemical instability over 18-24 hours. The bacteriostatic MICs by kill curve were not significantly different from those of cefuroxime...
  12. ncbi request reprint Temporal relationship between prevalence of meticillin-resistant Staphylococcus aureus (MRSA) in one hospital and prevalence of MRSA in the surrounding community: a time-series analysis
    F M MacKenzie
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    J Hosp Infect 67:225-31. 2007
    ..These results suggest that the reason for the increase in MRSA prevalence in the community was a hospital MRSA outbreak. Screening at patient discharge should be evaluated as a new measure to control spread of MRSA in the community...
  13. doi request reprint Report of a hospital neonatal unit outbreak of community-associated methicillin-resistant Staphylococcus aureus
    I M Gould
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    Epidemiol Infect 137:1242-8. 2009
    ..Region-wide surveillance of over 6000 MRSA isolates collected from 1998 to 2004 showed that 95 (1.6%) were closely related to the outbreak strain although only 60 carried the ETA gene. The strain has not been seen elsewhere in Scotland...
  14. ncbi request reprint Towards a European strategy for controlling antibiotic resistance Nijmegen, Holland August 29-31, 1999
    I M Gould
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Clin Microbiol Infect 6:670-4. 2000
    ....
  15. ncbi request reprint Molecular epidemiology and antibiotic resistance of Enterobacter spp. from three distinct populations in Grampian, UK
    F M E Wagenlehner
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, UK
    Int J Antimicrob Agents 20:419-25. 2002
    ..Isolates (27%) were clonally related and typed in four clusters. Consecutive isolates were studied in selected patients showing minor genomic changes. One environmental isolate from a deep sink at ITU was related to a patient's isolate...
  16. ncbi request reprint Antibiograms of resistant Gram-negative bacteria from Scottish CF patients
    F M MacKenzie
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    J Cyst Fibros 3:151-7. 2004
    ..Over a 19-month pilot phase, 93 multiply resistant Gram-negative isolates from Scottish cystic fibrosis patients were sent to a referral laboratory for further investigation...
  17. ncbi request reprint Antibiotic consumption in European hospitals
    F M MacKenzie
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, Scotland
    Med Mal Infect 35:S121-2. 2005
  18. ncbi request reprint Antibiotic exposure as a risk factor for emergence of resistance: the influence of concentration
    I M Gould
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    J Appl Microbiol 92:78S-84S. 2002
    ..Lastly, the relevance of all this to the development of resistance in the normal bacterial flora will be discussed...
  19. ncbi request reprint Attitudes to antibiotic prescribing, resistance and bacteriology investigations amongst practitioners and patients in the Grampian region of Scotland
    Ian M Gould
    Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, Scotland
    Eur J Gen Pract 13:35-6. 2007
  20. ncbi request reprint Topical antimicrobials in combination with admission screening and barrier precautions to control endemic methicillin-resistant Staphylococcus aureus in an Intensive Care Unit
    Ian M Gould
    Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
    Int J Antimicrob Agents 29:536-43. 2007
    ..001), as did the trend in glycopeptide use (P=0.014). An inexpensive and easy to implement intervention to control MRSA in the ICU was highly successful without compromising antimicrobial susceptibility...
  21. pmc Antimicrobial drug use and methicillin-resistant Staphylococcus aureus, Aberdeen, 1996-2000
    Dominique L Monnet
    Statens Serum Institut, Copenhagen, Denmark
    Emerg Infect Dis 10:1432-41. 2004
    ..Although these results may not be generalized to other hospitals, they suggest new directions for control of MRSA, which has thus far proved difficult and expensive...
  22. ncbi request reprint Information contained in miscarriage-related websites and the predictive value of website scoring systems
    J Christopher R Hardwick
    Princess Royal Maternity Hospital, 16 Alexander Parade, G31 2ER, Glasgow, UK
    Eur J Obstet Gynecol Reprod Biol 106:60-3. 2003
    ..The value of 'Silberg' and 'Health on the net (HON)' website scoring systems in predicting the information provided via websites identified was assessed...