David J Lunn

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Automated covariate selection and Bayesian model averaging in population PK/PD models
    David J Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB20SR, UK
    J Pharmacokinet Pharmacodyn 35:85-100. 2008
  2. doi request reprint Combining MCMC with 'sequential' PKPD modelling
    David Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, UK
    J Pharmacokinet Pharmacodyn 36:19-38. 2009
  3. doi request reprint The BUGS project: Evolution, critique and future directions
    David Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB2 0SR, U K
    Stat Med 28:3049-67. 2009
  4. pmc Fitting dynamic models with forcing functions: application to continuous glucose monitoring in insulin therapy
    D J Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, U K
    Stat Med 30:2234-50. 2011

Detail Information

Publications5

  1. ncbi request reprint Automated covariate selection and Bayesian model averaging in population PK/PD models
    David J Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB20SR, UK
    J Pharmacokinet Pharmacodyn 35:85-100. 2008
    ..The illustrative data that we consider pertain to the drug vancomycin in 59 neonates and infants, and all analyses are conducted using the WinBUGS software with newly developed 'Jump' interface installed...
  2. doi request reprint Combining MCMC with 'sequential' PKPD modelling
    David Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, UK
    J Pharmacokinet Pharmacodyn 36:19-38. 2009
    ..This is in contrast to standard two-stage approaches whereby 'plug-in' point estimates for either the population or the individual-specific PK parameters are required...
  3. doi request reprint The BUGS project: Evolution, critique and future directions
    David Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB2 0SR, U K
    Stat Med 28:3049-67. 2009
    ..We also present a historical overview of the BUGS project and some future perspectives...
  4. pmc Fitting dynamic models with forcing functions: application to continuous glucose monitoring in insulin therapy
    D J Lunn
    Medical Research Council Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, U K
    Stat Med 30:2234-50. 2011
    ..This leads to some identifiability issues but gives very good predictions of virtual data. Our approach is pragmatic and we propose a method to mitigate the consequences of such identifiability issues...