Affiliation: University College London
- Endoscopic resection of malignant tumors of the nose and sinusesValerie Lund
Institute of Laryngology and Otology, London, United Kingdom
Am J Rhinol 21:89-94. 2007..However, the rarity and long natural history of malignant tumors make it difficult to accrue cohorts comparable with the established gold standard of craniofacial resection...
- Maximal medical therapy for chronic rhinosinusitisValerie J Lund
The Ear Institute, University College London, 330 Gray s Inn Road, London WC1X 8DA, UK
Otolaryngol Clin North Am 38:1301-10, x. 2005..This article discusses CRS without nasal polyposis. The discussion of maximal medical therapy concentrates on the best available evidence from published clinical trials...
- Rhinosinusitis: developing guidance for clinical trialsEli O Meltzer
Allergy and Asthma Medical Group and Research Center and Department of Pediatrics, University of California, San Diego, USA
J Allergy Clin Immunol 118:S17-61. 2006....
- Diagnostic tools in Rhinology EAACI position paperGlenis Scadding
Royal National Throat, Nose and Ear Institute, London, UK
Clin Transl Allergy 1:2. 2011..A panel of European experts in the field of Rhinology has contributed to this consensus document on Diagnostic Tools in Rhinology...
- Sinonasal malignant melanoma: an analysis of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resectionV J Lund
University College London, Ear Institute, London, United Kingdom
Rhinology 50:203-10. 2012..Melanomas account for 4% of sinonasal malignancies. We present the largest single institution series reported thus far and analyze the outcome with reference to lymph node involvement, radiotherapy and endoscopic resection...
- Evidence-based surgery in chronic rhinosinusitisV J Lund
Institute of Laryngology and Otology, University College London, UK
Acta Otolaryngol 121:5-9. 2001..placebo-controlled trials. This review considers the evidence available in the literature for surgery in chronic rhinosinusitis and examines the validity of the studies in the context of evidence-based medicine...
- Efficacy of fusafungine in acute rhinopharyngitis: a pooled analysisV J Lund
Institute of Laryngology and Otology, University College London, Medical School, Royal National Throat Nose and Ear Hospital, United Kingdom
Rhinology 42:207-12. 2004..08 (p=0.033) in favour of fusafungine. Therefore fusafungine through its dual bacteriostatic and original anti-inflammatory properties is an effective treatment of acute rhinopharyngitis especially when administered early...
- Efficacy and tolerability of budesonide aqueous nasal spray in chronic rhinosinusitis patientsValerie J Lund
Royal National Throat, Nose and Ear Hospital, London, United Kingdom
Rhinology 42:57-62. 2004..14 [-0.81, 1.09]) were not significant. PNIF was significantly (p < 0.01) increased in both allergic and non-allergic patients from baseline versus placebo. BANS is an effective and well-tolerated treatment for chronic rhinosinusitis...
- Yearly incidence of rhinitis, nasal bleeding, and other nasal symptoms in mature womenValerie J Lund
Institute of Laryngology and Otology, Royal National Throat, Nose and Ear Hospital, London, United Kingdom
Rhinology 44:26-31. 2006..To evaluate, by a prospective questionnaire study, the incidence of spontaneous nasal pathology in mature women over a 12-month period, in particular nasal bleeding and the relationships of these symptoms with various factors...
- Distant metastases from sinonasal cancerV J Lund
Institute of Laryngology and Otology, Royal National Throat Nose and Ear Hospital, London, UK
ORL J Otorhinolaryngol Relat Spec 63:212-3. 2001..Notwithstanding this, the frequency with which systemic metastases occurs is such that screening at presentation could not be regarded as cost-effective and is consequently only instituted in the presence of specific symptoms...
- Olfactory neuroblastoma: past, present, and future?Valerie J Lund
Institute of Laryngology and Otology, University College London, 330 Gray s Inn Road, London WC1X 8DA, UK
Laryngoscope 113:502-7. 2003..To consider the long-term survival and outcomes in patients with olfactory neuroblastoma undergoing craniofacial resection...
- Therapeutic targets in rhinosinusitis: infection or inflammation?Valerie J Lund
The Ear Institute, University College London, London, United Kingdom
Medscape J Med 10:105. 2008..Controlling the inflammation will attenuate many of the symptoms of RS, including nasal blockage discharge, facial discomfort, headache, and hyposmia, and promote the clearance of the infectious agent...
- Health related quality of life in sinonasal diseaseV J Lund
Institute of Laryngology and Otology, University College London, 330 Gray s Inn Road, London, United Kingdom
Rhinology 39:182-6. 2001..These have been applied to a range of sinonasal conditions including allergy, infection and neoplasia. With increasing refinement they may become the main primary outcome measures in both clinical trials and practice...
- Long-term outcomes from the English national comparative audit of surgery for nasal polyposis and chronic rhinosinusitisClaire Hopkins
Ear, Nose and Throat Department, Guys and St Thomas Hospital, London, United Kingdom
Laryngoscope 119:2459-65. 2009..Five-year outcomes will be reported, and we will revisit a previous analysis of the effectiveness of extensive surgery in the treatment of nasal polyposis...
- Complications of surgery for nasal polyposis and chronic rhinosinusitis: the results of a national audit in England and WalesClaire Hopkins
Clinical Effectiveness Unit, The Royal College of Surgeons of England, 35-43 Lincoln's Inn Fields, London, UK
Laryngoscope 116:1494-9. 2006..CONCLUSIONS: The risk of complications depended on patient characteristics rather than on the surgical technique used. Measures of the extent of disease and comorbidity may help in identifying patients at high risk of complications...
- Impact of chronic rhinosinusitis on quality of life and health care expenditureValerie J Lund
Professorial Unit, Institute of Laryngology and Otology, University College London, London, UK
Clin Allergy Immunol 20:15-24. 2007
- The relationship between subjective assessment instruments in chronic rhinosinusitisMingyann Lim
Professorial Unit, Royal National Throat, Nose and Ear Hospital, London, United Kingdom
Rhinology 45:144-7. 2007....
- Craniofacial resection for tumors of the nasal cavity and paranasal sinuses: a 25-year experienceDavid J Howard
Institute of Laryngology and Otology, University College London, 330 Gray's Inn Road, London WC1X 8DA, United Kingdom
Head Neck 28:867-73. 2006..CONCLUSION: Analysis of one of the largest single institution cohorts over a 25-year period provides a baseline against which other approaches such as an entirely endoscopic skull base resection must be judged...
- Health-related quality of life after polypectomy with and without additional surgeryJohn Patrick Browne
Clinical Effectiveness Unit, Royal College of Surgeons of England, London, and the Royal United Hospital Bath, Bath, Somerset, United Kingdom
Laryngoscope 116:297-302. 2006..The objective of this study was to compare the health-related quality of life of patients undergoing simple polypectomy with that of patients undergoing polypectomy with additional surgery...
- Maxillary mucosal cyst is not a manifestation of rhinosinusitis: results of a prospective three-dimensional CT study of ophthalmic patientsJeeve Kanagalingam
Royal National Throat Nose and Ear Hospital, London, United Kingdom
Laryngoscope 119:8-12. 2009..Mucosal cysts in the maxillary antrum (MMC) are a common finding in imaging of the paranasal sinuses. Their significance remains in doubt and their prevalence in the general nonrhinitic population is unknown...
- Imaging of sinonasal tumorsGitta Madani
Imperial College NHS Trust, St Mary s Hospital, London, UK
Semin Ultrasound CT MR 30:25-38. 2009..The sites and patterns of tumor recurrence and the imaging features of recurrent tumor are also discussed...
- The impact of septodermoplasty and potassium-titanyl-phosphate (KTP) laser therapy in the treatment of hereditary hemorrhagic telangiectasia-related epistaxisRichard J Harvey
Rhinology Research Unit, Royal National Throat Nose and Ear Hospital, London WC1X 8DA, United Kingdom
Am J Rhinol 22:182-7. 2008..The frequency and interval between procedures is not well documented. The purpose of this study was to describe the frequency of surgical interventions for HHT patients and the impact of SDP...
- Rhinologic changes in Wegener's granulomatosisGlyn Lloyd
Royal National Throat, Nose and Ear Hospital, London, UK
J Laryngol Otol 116:565-9. 2002..These changes are important diagnostically in localized sinonasal Wegener's granulomatosis where the clinical diagnosis may be uncertain and the cANCA test can be negative...
- Endoscopic management of cerebrospinal fluid leaksValerie J Lund
Institute of Laryngology and Otology, University College London, United Kingdom
Am J Rhinol 16:17-23. 2002..Therefore, it is our preferred option, although surgeons must be prepared for alternative procedures should these prove necessary...
- The effect of treatment for epistaxis secondary to hereditary hemorrhagic telangiectasiaAnne E Hitchings
Professorial Unit, Royal National Throat Nose and Ear Hospital, London, United Kingdom
Am J Rhinol 19:75-8. 2005..CONCLUSION: Nasal closure should be offered to patients with moderate to severe epistaxis secondary to hereditary hemorrhagic telangiectasia that has proved unresponsive to other treatment...
- Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosisSantdeep Paun
Royal National Throat, Nose and Ear Hospital, London, UK
J Laryngol Otol 119:119-24. 2005..The disease process, with its clinical and characteristic histopathological findings, is described. We also discuss the management of the disease following a comprehensive review of, and comparison with, the few prior reported cases...
- The SF-36 health status questionnaire in assessing patients with epistaxis secondary to hereditary hemorrhagic telangiectasiaPenelope A Lennox
Professorial Unit, The Royal National Throat Nose and Ear Hospital, London, United Kingdom
Am J Rhinol 19:71-4. 2005..05). CONCLUSION: The SF-36 reflects the reduced health status of patients with epistaxis due to HHT. Changes in the SF-36 score could be used as an outcome measure in assessing efficacy of treatment of this condition...
- Ethnic variation in sinonasal anatomy on CT-scanningLydia Badia
The Royal National Throat, Nose and Ear Hospital, London, United Kingdom
Rhinology 43:210-4. 2005..Although there is no evidence that variants of the sinonasal anatomy seen on CT Scan have a causative effect in the disease process; a knowledge of their presence is paramount in minimising the potential for surgical complications...
- Evaluation of the medical and surgical treatment of chronic rhinosinusitis: a prospective, randomised, controlled trialSameh M Ragab
Tanta University Hospitals, Egypt
Laryngoscope 114:923-30. 2004..The presence of nasal polyps is not a poor prognostic factor for the efficacy of CRS therapy, either surgical or medical...
- Acute rhinosinusitis--old disease, new perspectivesValerie J Lund
Rhinology 45:177. 2007
- Esthesioneuroblastoma and cervical lymph node metastases: clinical and therapeutic implicationsAlessandra Rinaldo
Department of Otolaryngology-Head and Neck Surgery, University of Udine, Policlinico Universitario, Italy
Acta Otolaryngol 122:215-21. 2002
- Etiology of chronic rhinosinusitis: the role of fungusDaniel L Hamilos
Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Otol Rhinol Laryngol Suppl 193:27-31. 2004..Further study is also required to define the optimal treatment for the disease...
- Surgical outcomes in chronic rhinosinusitis and nasal polyposisValerie J Lund
Rhinology 44:97. 2006
- Judicious antibiotic use and intranasal corticosteroids in acute rhinosinusitisCatherine Butkus Small
Division of Infectious Diseases, Department of Medicine, New York Medical College, Westchester Medical Center, Valhalla 10595, USA
Am J Med 120:289-94. 2007..The use of intranasal corticosteroids in acute rhinosinusitis therefore might reduce the inappropriate use of antimicrobial therapy in acute rhinosinusitis...
- Rhinosinusitis: Developing guidance for clinical trialsEli O Meltzer
Allergy and Asthma Medical Group and Research Center Department of Pediatrics, University of California, San Diego, San Diego, California
Otolaryngol Head Neck Surg 135:S31-80. 2006....
- Management of the orbit in malignant sinonasal tumorsCarlos Suarez
Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain
Head Neck 30:242-50. 2008..Microvascular free-tissue transfer is the best option for repair of defects following orbital exenteration and total maxillectomy, although an obturator still has a role in selected patients...
- The role of mitomycin C in surgery of the frontonasal recess: a prospective open pilot studyKwame Amonoo-Kuofi
Institute of Laryngology and Otology, University College London, London, United Kingdom
Am J Rhinol 20:591-4. 2006..Mean follow-up was 19 months (range, 6-32 months). Patency rate was 86%. CONCLUSION: Mitomycin appears to have an important role in reducing postoperative scarring, which may obviate the need for repeated and more extensive surgery...
- Peak nasal inspiratory flow; normal range in adult populationGiancarlo Ottaviano
Department of Otolaryngology, Head and Neck Surgery, University of Padua, Padua, Italy
Rhinology 44:32-5. 2006..The study provides normative data for a Caucasian population. Further variables need to be explored to predict expected PNIF values more accurately...
- Database for the collection and analysis of clinical data and images of neoplasms of the sinonasal tractMatteo Trimarchi
Department of Otorhinolaryngology, San Raffaele University Hospital, Milan, Italy
Ann Otol Rhinol Laryngol 113:335-7. 2004..The development of a dedicated, user-friendly database for sinonasal neoplasia facilitates a multicenter network and has obvious clinical and research benefits...
- Clinical features and treatment of late enophthalmos after orbital decompression: a condition suggesting cause for idiopathic "imploding antrum" (silent sinus) syndromeGeoffrey E Rose
Orbital Service, Moorfields Eye Hospital, London, England
Ophthalmology 110:819-26. 2003..This iatrogenic condition, associated in most cases with inward collapse of the maxillary walls, provides a guide to a hypothetical mechanism for the idiopathic imploding antrum (silent sinus) syndrome...
- Improved visualisation to a range of proceduresValerie J Lund
Rhinology 43:241. 2005
- Eyelid fistula: a feature of occult sinus diseaseDavid Rossman
Moorfields Eye Hospital, London, UK
Orbit 26:159-63. 2007..To describe the clinical characteristics of patients presenting with eyelid fistula as a complication of occult sinus disease...