A N Lukashkin

Summary

Affiliation: University of Sussex
Country: UK

Publications

  1. ncbi Power amplification in the mammalian cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, UK
    Curr Biol 17:1340-4. 2007
  2. ncbi Dependence of the DPOAE amplitude pattern on acoustical biasing of the cochlear partition
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Hear Res 203:45-53. 2005
  3. doi Multiple roles for the tectorial membrane in the active cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Hear Res 266:26-35. 2010
  4. ncbi A self-mixing laser-diode interferometer for measuring basilar membrane vibrations without opening the cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    J Neurosci Methods 148:122-9. 2005
  5. ncbi Role of the tectorial membrane revealed by otoacoustic emissions recorded from wild-type and transgenic Tecta(deltaENT/deltaENT) mice
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom
    J Neurophysiol 91:163-71. 2004
  6. ncbi A second, low-frequency mode of vibration in the intact mammalian cochlea
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
    J Acoust Soc Am 113:1544-50. 2003
  7. ncbi Modifications of a single saturating non-linearity account for post-onset changes in 2f1-f2 distortion product otoacoustic emission
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, United Kingdom
    J Acoust Soc Am 112:1561-8. 2002
  8. ncbi One source for distortion product otoacoustic emissions generated by low- and high-level primaries
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Acoust Soc Am 111:2740-8. 2002
  9. ncbi Origin of the bell-like dependence of the DPOAE amplitude on primary frequency ratio
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Acoust Soc Am 110:3097-106. 2001
  10. ncbi A descriptive model of the receptor potential nonlinearities generated by the hair cell mechanoelectrical transducer
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, United Kingdom
    J Acoust Soc Am 103:973-80. 1998

Collaborators

Detail Information

Publications20

  1. ncbi Power amplification in the mammalian cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, UK
    Curr Biol 17:1340-4. 2007
    ..The finding also makes redundant current hypotheses of cochlear frequency sharpening and sensitization that are not based on negative damping...
  2. ncbi Dependence of the DPOAE amplitude pattern on acoustical biasing of the cochlear partition
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Hear Res 203:45-53. 2005
    ....
  3. doi Multiple roles for the tectorial membrane in the active cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Hear Res 266:26-35. 2010
    ..The role of the tectorial membrane in distributing energy along the cochlear partition and how it channels this energy to the inner hair cells is described...
  4. ncbi A self-mixing laser-diode interferometer for measuring basilar membrane vibrations without opening the cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    J Neurosci Methods 148:122-9. 2005
    ..The interferometer provides a viable means for making subnanometre mechanical measurements from structures in the inner ears of small mammals, where opening of the cochlea is not practicable...
  5. ncbi Role of the tectorial membrane revealed by otoacoustic emissions recorded from wild-type and transgenic Tecta(deltaENT/deltaENT) mice
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom
    J Neurophysiol 91:163-71. 2004
    ..A nonlinear low-frequency resonance, revealed by nonmonotonicity of the phase behavior, was seen in the wild-type but not in Tecta(deltaENT/deltaENT) mice...
  6. ncbi A second, low-frequency mode of vibration in the intact mammalian cochlea
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
    J Acoust Soc Am 113:1544-50. 2003
    ....
  7. ncbi Modifications of a single saturating non-linearity account for post-onset changes in 2f1-f2 distortion product otoacoustic emission
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, United Kingdom
    J Acoust Soc Am 112:1561-8. 2002
    ....
  8. ncbi One source for distortion product otoacoustic emissions generated by low- and high-level primaries
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Acoust Soc Am 111:2740-8. 2002
    ....
  9. ncbi Origin of the bell-like dependence of the DPOAE amplitude on primary frequency ratio
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Acoust Soc Am 110:3097-106. 2001
    ..The difference between the DPOAE recorded from guinea pigs and humans is discussed in terms of different position of the operating point of the DPOAE generating nonlinearity...
  10. ncbi A descriptive model of the receptor potential nonlinearities generated by the hair cell mechanoelectrical transducer
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, United Kingdom
    J Acoust Soc Am 103:973-80. 1998
    ..The model also shows that there is non-monotonic growth and phase change for any spectral component, but not for the fundamental of the receptor potential...
  11. ncbi Properties of distortion product otoacoustic emissions and neural suppression tuning curves attributable to the tectorial membrane resonance
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom
    J Acoust Soc Am 121:337-43. 2007
    ..The emission bandpass structure is, however, likely to be generated by a combination of mechanisms with different ones dominating at different stimulus parameters...
  12. ncbi A deafness mutation isolates a second role for the tectorial membrane in hearing
    P Kevin Legan
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 8:1035-42. 2005
    ..Thus, using Tecta(Y1870C/+) mice, we have genetically isolated a second major role for the tectorial membrane in hearing: it enables the motion of the basilar membrane to optimally drive the inner hair cells at their best frequency...
  13. doi Outer hair cell somatic, not hair bundle, motility is the basis of the cochlear amplifier
    Marcia M Mellado Lagarde
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 11:746-8. 2008
    ..We conclude that somatic, and not stereocilia, motility is the basis of cochlear amplification...
  14. pmc The tectorial membrane: one slice of a complex cochlear sandwich
    Guy P Richardson
    School of Life Sciences, University of Sussex, Falmer, Brighton, UK
    Curr Opin Otolaryngol Head Neck Surg 16:458-64. 2008
    ....
  15. pmc Sharpened cochlear tuning in a mouse with a genetically modified tectorial membrane
    Ian J Russell
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 10:215-23. 2007
    ..These findings can be attributed to a reduction in the acting mass of the tectorial membrane and reveal a new function for this structure in controlling interactions along the cochlea...
  16. pmc Frequency-dependent properties of the tectorial membrane facilitate energy transmission and amplification in the cochlea
    G P Jones
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, United Kingdom
    Biophys J 104:1357-66. 2013
    ..This prediction is confirmed by neural recordings from several frequency regions of the cochlea...
  17. doi The role of prestin in the generation of electrically evoked otoacoustic emissions in mice
    Markus Drexl
    University of Sussex, School of Life Sciences, Brighton, UK
    J Neurophysiol 99:1607-15. 2008
    ..We conclude that near threshold, the emissions are generated by prestin-based somatic motility...
  18. ncbi The voltage dependence of the mechanoelectrical transducer modifies low frequency outer hair cell electromotility in vitro
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, UK
    Hear Res 113:133-9. 1997
    ..Following treatment of the hair bundle with BAPTA or dihydrostreptomycin, which are known to impair transduction function (Assad et al., 1991; Kroese et al., 1989), rectification of the motile response disappeared...
  19. doi Prestin's role in cochlear frequency tuning and transmission of mechanical responses to neural excitation
    Marcia M Mellado Lagarde
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
    Curr Biol 18:200-2. 2008
    ..Prestin is crucial for defining sharp and sensitive cochlear frequency tuning by reducing the sensitivity of the low-frequency tail of the tuning curve, although this necessitates a cochlear amplifier to determine the narrowly tuned tip...
  20. pmc The dynein-tubulin motor powers active oscillations and amplification in the hearing organ of the mosquito
    Ben Warren
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Proc Biol Sci 277:1761-9. 2010
    ..If, as has been claimed for insect and vertebrate hearing organs, spontaneous oscillations epitomize amplification, then in the mosquito ear, this process is independent of mechanotransduction...