Research Topics
Species | A LucasSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Infant feeding bottle design, growth and behaviour: results from a randomised trialM S Fewtrell
MRC Childhood Nutrition Research Centre, UCL Institute of Child Health, London, UK
BMC Res Notes 5:150. 2012..Whether the design of an anti-vacuum infant feeding bottle influences infant milk intake, growth or behavior is unknown, and was the subject of this randomized trial...
Randomised trial of early diet in preterm babies and later intelligence quotientA Lucas
Medical Research Council Childhood Nutrition Research Centre, Institute of Child Health, London WC1N 1EH, UK
BMJ 317:1481-7. 1998..To determine whether perinatal nutrition influences cognitive function at 7 1/2 - 8 years in children born preterm...
Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial functionC P M Leeson
Medical Research Council Childhood Nutrition Research Centre, Institute of Child Health, University College, London
Circ Res 90:1153-8. 2002..These findings raise the possibility of genotype-specific prevention strategies in cardiovascular disease...
Plasma vitamin E, total antioxidant status and vascular function in young adultsC P M Leeson
Medical Research Council Childhood Nutrition Research Centre, Institute of Child Health, University College London, UK
Eur J Clin Invest 32:889-94. 2002..CONCLUSIONS: Neither plasma vitamin E concentrations nor total antioxidant status achieved by dietary intake during young adulthood were related to vascular endothelial function or arterial distensibility...
Validation of food diary method for assessment of dietary energy and macronutrient intake in infants and children aged 6-24 monthsJ A Lanigan
Institute of Child Health, London, UK
Eur J Clin Nutr 55:124-9. 2001....
Duration of breast feeding and arterial distensibility in early adult life: population based studyC P Leeson
Medical Research Council Childhood Nutrition Research Centre, Institute of Child Health, London WC1N 1EH
BMJ 322:643-7. 2001..To test the hypothesis that duration of breast feeding is related to changes in vascular function relevant to the development of cardiovascular disease...
Early nutrition in preterm infants and later blood pressure: two cohorts after randomised trialsA Singhal
Medical Research Council Childhood Nutrition Research Centre, Institute of Child Health, London, UK
Lancet 357:413-9. 2001..We undertook such a study to test the hypothesis that early diet programmes blood pressure in later life in children randomly assigned different diets at birth...
Low plasma taurine and later neurodevelopmentB A Wharton
Childhood Nutrition Research Centre, Institute of Child Health, London WC1 1EH, UK
Arch Dis Child Fetal Neonatal Ed 89:F497-8. 2004..Low plasma neonatal taurine was associated with lower scores on the Bayley mental development index at 18 months and the WISC-R arithmetic subtest at 7 years. Currently it is not mandatory to add taurine to infant formulas...
Brain morphometry and IQ measurements in preterm childrenE B Isaacs
MRC Childhood Nutrition Research Centre, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
Brain 127:2595-607. 2004..Whether this is true of children born at >30 weeks gestation and what other factors predispose to this decline have yet to be determined...
Calculation difficulties in children of very low birthweight: a neural correlateE B Isaacs
MRC Childhood Nutrition Research Centre and Radiology and Physics Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
Brain 124:1701-7. 2001..To our knowledge, this is the first report establishing a structural neural correlate of calculation ability in a group of neurologically normal individuals...
Factors associated with weaning in full term and preterm infantsM S Fewtrell
MRC Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Arch Dis Child Fetal Neonatal Ed 88:F296-301. 2003..The optimal age for the introduction of solid foods (weaning) in infants is poorly researched yet may have implications for both short and longer term health. Many parents do not comply with current guidelines...
A simplified approach to analysing bio-electrical impedance data in epidemiological surveysJ C K Wells
MRC Childhood Nutrition Research Centre, Institute of Child Health, London, UK
Int J Obes (Lond) 31:507-14. 2007..It is simple, quick and cheap, but less accurate than other methods. It has potential epidemiological value, but has conventionally required validation before application...
Clinical safety of iron-fortified formulasA Singhal
Medical Research Council Childhood Nutrition Research Centre, Institute of Child Health, London, United Kingdom
Pediatrics 105:E38. 2000..Iron could theoretically increase pro-oxidant stress, with potential adverse effects, including infection risk, and some clinicians suspect that iron-fortified formulas induce gastrointestinal disturbance...
Randomized study comparing the efficacy of a novel manual breast pump with a mini-electric breast pump in mothers of term infantsM Fewtrell
MRC Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
J Hum Lact 17:126-31. 2001..Despite the greater complexity and expense of the MEP, the pumps showed similar efficacy. The MP was preferred by mothers. The novel, more physiological operation of the MP represents an advance in milk expression technology...
Effects of growth during infancy and childhood on bone mineralization and turnover in preterm children aged 8-12 years- Fewtrell
MRC Childhood Nutrition Research Centre, Institute of Child Health, London, UK
Acta Paediatr 89:148-53. 2000..These findings raise the hypothesis that improving linear growth in vulnerable children may be important in maximizing bone mass...
Number of days needed to assess energy and nutrient intake in infants and young children between 6 months and 2 years of ageJ A Lanigan
MRC Childhood Nutrition Research Centre, Institute of Child Health, London, UK
Eur J Clin Nutr 58:745-50. 2004..To estimate the minimum number of days of recorded dietary intake needed to place infants and young children into thirds of a population distribution with an acceptable degree of accuracy...
Developmental amnesia and its relationship to degree of hippocampal atrophyE B Isaacs
Institute of Child Health, University College London, London WC1N 1EH, United Kingdom
Proc Natl Acad Sci U S A 100:13060-3. 2003..Whether this is a sufficient condition for the disorder or whether abnormality in other brain regions is also necessary remains to be determined...
Relationship between circulating n-3 fatty acid concentrations and endothelial function in early adulthoodC P M Leeson
Medical Research Council Childhood Nutrition Research Centre, University College, London, UK
Eur Heart J 23:216-22. 2002..This raises the possibility that physiological levels of circulating n-3 fatty acids may protect the endothelium from early adulthood...
Cholesterol metabolism in 8 to 12-year-old children born preterm or at termM Mortaz
Department of Nutrition and Dietetics, King's College London, London, UK
Acta Paediatr 92:525-30. 2003..Those born prematurely had lower cholesterol synthesis and breakdown, but their plasma cholesterol concentration was similar at this age. These parameters need to be studied in older cohorts...
Randomized trial of nutrient-enriched formula versus standard formula for postdischarge preterm infantsA Lucas
MRC Childhood Nutrition Research Centre, Institute of Child Health, London, England
Pediatrics 108:703-11. 2001..3) Our data raise the possibility that breastfed postdischarge preterm infants may require nutritional supplementation, currently under investigation...
Does weaning influence growth and health up to 18 months?J B Morgan
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK
Arch Dis Child 89:728-33. 2004..National and international recommendations for the age of introducing solid foods (weaning) are founded on insufficient evidence and little is known about the short and medium term consequences associated with early or late weaning...
Bone mineralization and turnover in preterm infants at 8-12 years of age: the effect of early dietM S Fewtrell
MRC Human Nutrition Research (formerly Dunn Nutritional Laboratory, Cambridge, United Kingdom
J Bone Miner Res 14:810-20. 1999..However, poor nutrition during the neonatal period may result in higher bone formation rates during childhood...
Neonatal factors predicting childhood height in preterm infants: evidence for a persisting effect of early metabolic bone disease?M S Fewtrell
MRC Childhood Nutrition Research Centre, Institute of Child Health, London, United Kingdom
J Pediatr 137:668-73. 2000..We aimed to further investigate factors predicting childhood height and to test the hypothesis that evidence of early metabolic bone disease is associated with reduced later height...
Effects of size at birth, gestational age and early growth in preterm infants on glucose and insulin concentrations at 9-12 yearsM S Fewtrell
University Department of Clinical Biochemistry, Addenbrooke's Hospital, Cambridge, UK
Diabetologia 43:714-7. 2000..In contrast, childhood weight gain is the most important factor influencing insulin concentrations and this effect is the same regardless of early size...
