Edward J Louis

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum
    Rosanna Young
    Peter Medawar Building for Pathogen Research, University of Oxford, South Parks Road, Oxford, OX1 3SY, UK
    BMC Genomics 9:385. 2008
  2. doi request reprint Saccharomyces cerevisiae: gene annotation and genome variability, state of the art through comparative genomics
    Ed Louis
    Institute of Genetics, Queens Medical Centre, University of Nottingham, Nottingham, UK
    Methods Mol Biol 759:31-40. 2011
  3. pmc Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae
    Esther R Loney
    Institute of Genetics, University of Nottingham, Nottingham, UK
    Epigenetics Chromatin 2:18. 2009
  4. pmc In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway
    Marcus E Marvin
    Institute of Genetics, University of Nottingham, Medical School, Queens Medical Centre, Nottingham, UK
    Genetics 183:441-51, 1SI-12SI. 2009
  5. pmc Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast
    Gianni Liti
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, Nottingham, United Kingdom
    PLoS Genet 5:e1000659. 2009
  6. pmc Population genomics of domestic and wild yeasts
    Gianni Liti
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    Nature 458:337-41. 2009
  7. doi request reprint Assessing the complex architecture of polygenic traits in diverged yeast populations
    Francisco A Cubillos
    Centre for Genetics and Genomics, Queen s Medical Centre, University of Nottingham, Nottingham, UK
    Mol Ecol 20:1401-13. 2011
  8. pmc Apparent ploidy effects on silencing are post-transcriptional at HML and telomeres in Saccharomyces cerevisiae
    Jenny M McLaughlan
    Centre for Genetics and Genomics, Queen s Medical Centre, University of Nottingham, Nottingham, United Kingdom
    PLoS ONE 7:e39044. 2012
  9. pmc The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences
    Marcus E Marvin
    Institute of Genetics, University of Nottingham, Medical School, Queen s Medical Centre, Nottingham, UK
    Genetics 183:453-67, 1SI-13SI. 2009
  10. pmc High-resolution mapping of complex traits with a four-parent advanced intercross yeast population
    Francisco A Cubillos
    Centre for Genetics and Genomics, Queen s Medical Centre, University of Nottingham, Nottingham, NG7 2UH, United Kingdom
    Genetics 195:1141-55. 2013

Collaborators

Detail Information

Publications13

  1. pmc Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum
    Rosanna Young
    Peter Medawar Building for Pathogen Research, University of Oxford, South Parks Road, Oxford, OX1 3SY, UK
    BMC Genomics 9:385. 2008
    ..We have previously developed a method to selectively isolate sets of trypanosome BES containing telomeres using Transformation associated recombination (TAR) cloning in yeast...
  2. doi request reprint Saccharomyces cerevisiae: gene annotation and genome variability, state of the art through comparative genomics
    Ed Louis
    Institute of Genetics, Queens Medical Centre, University of Nottingham, Nottingham, UK
    Methods Mol Biol 759:31-40. 2011
    ....
  3. pmc Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae
    Esther R Loney
    Institute of Genetics, University of Nottingham, Nottingham, UK
    Epigenetics Chromatin 2:18. 2009
    ..CONCLUSION: Our data identifies chromatin features that correlate with the silencing state and indicate that an array of phased nucleosomes is not sufficient for full repression...
  4. pmc In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway
    Marcus E Marvin
    Institute of Genetics, University of Nottingham, Medical School, Queens Medical Centre, Nottingham, UK
    Genetics 183:441-51, 1SI-12SI. 2009
    ..Furthermore, core X bestowed this protection as part of the same pathway as yKu. Our findings implicate a role for both yKu and core X in stabilizing the genome against recombination events involving telomeric sequences...
  5. pmc Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast
    Gianni Liti
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, Nottingham, United Kingdom
    PLoS Genet 5:e1000659. 2009
    ..Furthermore, we propose that sequence divergence within the Ku heterodimer generates negative epistasis within one of the allelic combinations (American-YKU70 and European-YKU80) resulting in very short telomeres...
  6. pmc Population genomics of domestic and wild yeasts
    Gianni Liti
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    Nature 458:337-41. 2009
    ....
  7. doi request reprint Assessing the complex architecture of polygenic traits in diverged yeast populations
    Francisco A Cubillos
    Centre for Genetics and Genomics, Queen s Medical Centre, University of Nottingham, Nottingham, UK
    Mol Ecol 20:1401-13. 2011
    ..This set of recombinant strains is a powerful tool for investigating the complex architecture of polygenic traits...
  8. pmc Apparent ploidy effects on silencing are post-transcriptional at HML and telomeres in Saccharomyces cerevisiae
    Jenny M McLaughlan
    Centre for Genetics and Genomics, Queen s Medical Centre, University of Nottingham, Nottingham, United Kingdom
    PLoS ONE 7:e39044. 2012
    ..The post-transcriptional effects seen in this study, illustrate the often ignored need to measure RNA levels when assaying transcriptional silencing in Saccharomyces cerevisiae...
  9. pmc The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences
    Marcus E Marvin
    Institute of Genetics, University of Nottingham, Medical School, Queen s Medical Centre, Nottingham, UK
    Genetics 183:453-67, 1SI-13SI. 2009
    ..We believe our findings support our hypothesis that yKu and core X play a pivotal role in maintaining genome stability through nuclear architecture by mediating a defensive fold-back structure at yeast chromosome ends...
  10. pmc High-resolution mapping of complex traits with a four-parent advanced intercross yeast population
    Francisco A Cubillos
    Centre for Genetics and Genomics, Queen s Medical Centre, University of Nottingham, Nottingham, NG7 2UH, United Kingdom
    Genetics 195:1141-55. 2013
    ..SGRP-4X is a deeply characterized resource that provides a framework for powerful and high-resolution genetic analysis of yeast phenotypes and serves as a test bed for testing avenues to attack human complex traits. ..
  11. doi request reprint Generation of a large set of genetically tractable haploid and diploid Saccharomyces strains
    Francisco A Cubillos
    Queen s Medical Centre, Institute of Genetics, University of Nottingham, Nottingham, UK
    FEMS Yeast Res 9:1217-25. 2009
    ..Three versions of each strain (haploid Mat a and Mat alpha and diploid Mat a/alpha all as ura3::KanMX-Barcode) are available through the National Culture Yeast Collection...
  12. pmc Sequence diversity, reproductive isolation and species concepts in Saccharomyces
    Gianni Liti
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom
    Genetics 174:839-50. 2006
    ..There is molecular evidence of recent introgression from S. cerevisiae into the European population of S. paradoxus, supporting the idea that in nature the boundary between these species is fuzzy...
  13. ncbi request reprint Yeast evolution and comparative genomics
    Gianni Liti
    Institute of Genetics, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Annu Rev Microbiol 59:135-53. 2005
    ..Future work on population genomics and experimental evolution will keep yeast at the forefront of studies in genome evolution...