R Lorenc

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Prediction of incident hip fracture risk by femur geometry variables measured by hip structural analysis in the study of osteoporotic fractures
    Stephen Kaptoge
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom
    J Bone Miner Res 23:1892-904. 2008
  2. doi request reprint Geographical variation in DXA bone mineral density in young European men and women. Results from the Network in Europe on Male Osteoporosis (NEMO) study
    Stephen Kaptoge
    Department of Medicine and Strangeways Research Laboratory, University of Cambridge, Wort s Causeway, Cambridge CB1 8RN, UK
    Bone 43:332-9. 2008
  3. ncbi request reprint Geographic and other determinants of BMD change in European men and women at the hip and spine. a population-based study from the Network in Europe for Male Osteoporosis (NEMO)
    S Kaptoge
    Strangeways Research Laboratory, Department of Medicine, University of Cambridge, Wort s Causeway Cambridge, UK
    Bone 40:662-73. 2007
  4. ncbi request reprint Effects of physical activity on evolution of proximal femur structure in a younger elderly population
    S Kaptoge
    Institute of Public Health, Strangeways Research Laboratory, University of Cambridge, Cambridge, UK
    Bone 40:506-15. 2007
  5. ncbi request reprint Sex hormone status may modulate rate of expansion of proximal femur diameter in older women alongside other skeletal regulators
    S Kaptoge
    Institute of Public Health and Department of Medicine, University of Cambridge, Cambridge CB1 8RN, United Kingdom
    J Clin Endocrinol Metab 92:304-13. 2007
  6. ncbi request reprint Low BMD is less predictive than reported falls for future limb fractures in women across Europe: results from the European Prospective Osteoporosis Study
    S Kaptoge
    Strangeways Research Laboratory, University of Cambridge, Wort s Causeway, Cambridge CB1 8RN, UK
    Bone 36:387-98. 2005
  7. ncbi request reprint Effects of dietary nutrients and food groups on bone loss from the proximal femur in men and women in the 7th and 8th decades of age
    S Kaptoge
    Strangeways Research Laboratory, University of Cambridge, Worts Causeway, CB1 8RN Cambridge, UK
    Osteoporos Int 14:418-28. 2003
  8. ncbi request reprint Hip section modulus, a measure of bending resistance, is more strongly related to reported physical activity than BMD
    S Kaptoge
    Strangeways Research Laboratory, Cambridge University, Worts Causeway, CB1 8RN, Cambridge, UK
    Osteoporos Int 14:941-9. 2003
  9. ncbi request reprint Determinants of the size of incident vertebral deformities in European men and women in the sixth to ninth decades of age: the European Prospective Osteoporosis Study (EPOS)
    J Reeve
    Department of Medicine, Addenbrooke s Hospital, Cambridge, United Kingdom
    J Bone Miner Res 18:1664-73. 2003
  10. ncbi request reprint Improving risk assessment: hip geometry, bone mineral distribution and bone strength in hip fracture cases and controls. The EPOS study. European Prospective Osteoporosis Study
    N J Crabtree
    University Department of Medicine, University of Cambridge, UK
    Osteoporos Int 13:48-54. 2002

Collaborators

Detail Information

Publications18

  1. pmc Prediction of incident hip fracture risk by femur geometry variables measured by hip structural analysis in the study of osteoporotic fractures
    Stephen Kaptoge
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom
    J Bone Miner Res 23:1892-904. 2008
    ..Fracture might require initiation (e.g., by localized crushing or buckling of the lateral cortex)...
  2. doi request reprint Geographical variation in DXA bone mineral density in young European men and women. Results from the Network in Europe on Male Osteoporosis (NEMO) study
    Stephen Kaptoge
    Department of Medicine and Strangeways Research Laboratory, University of Cambridge, Wort s Causeway, Cambridge CB1 8RN, UK
    Bone 43:332-9. 2008
    ..Hip BMD mean values were lower in European women, but SD's differed little from the NHANES-III USA results in both sexes. It may be necessary to adjust NHANES-III based T-scores by adding/subtracting a country-specific adjustment factor...
  3. ncbi request reprint Geographic and other determinants of BMD change in European men and women at the hip and spine. a population-based study from the Network in Europe for Male Osteoporosis (NEMO)
    S Kaptoge
    Strangeways Research Laboratory, Department of Medicine, University of Cambridge, Wort s Causeway Cambridge, UK
    Bone 40:662-73. 2007
    ....
  4. ncbi request reprint Effects of physical activity on evolution of proximal femur structure in a younger elderly population
    S Kaptoge
    Institute of Public Health, Strangeways Research Laboratory, University of Cambridge, Cambridge, UK
    Bone 40:506-15. 2007
    ..We hypothesised that stereotyped physical activity (e.g., walking) may help conserve bending resistance (section modulus, Z) through redistribution of bone tissue, but it might be at the expense of supero-lateral cortical stability...
  5. ncbi request reprint Sex hormone status may modulate rate of expansion of proximal femur diameter in older women alongside other skeletal regulators
    S Kaptoge
    Institute of Public Health and Department of Medicine, University of Cambridge, Cambridge CB1 8RN, United Kingdom
    J Clin Endocrinol Metab 92:304-13. 2007
    ..Little is known of associations between hip geometry and skeletal regulators. This is important because geometry is a determinant of both hip function and resistance to fracture...
  6. ncbi request reprint Low BMD is less predictive than reported falls for future limb fractures in women across Europe: results from the European Prospective Osteoporosis Study
    S Kaptoge
    Strangeways Research Laboratory, University of Cambridge, Wort s Causeway, Cambridge CB1 8RN, UK
    Bone 36:387-98. 2005
    ..These variations might reflect shared environmental or possibly genetic factors that contribute quite substantially to the risk of upper limb fractures in women...
  7. ncbi request reprint Effects of dietary nutrients and food groups on bone loss from the proximal femur in men and women in the 7th and 8th decades of age
    S Kaptoge
    Strangeways Research Laboratory, University of Cambridge, Worts Causeway, CB1 8RN Cambridge, UK
    Osteoporos Int 14:418-28. 2003
    ..The protective effect of vitamin C in women needs to be further investigated in other prospective cohort or intervention studies...
  8. ncbi request reprint Hip section modulus, a measure of bending resistance, is more strongly related to reported physical activity than BMD
    S Kaptoge
    Strangeways Research Laboratory, Cambridge University, Worts Causeway, CB1 8RN, Cambridge, UK
    Osteoporos Int 14:941-9. 2003
    ..These data are consistent with an effect of mechanical loading to regulate bone strength through an anabolic effect maximal in the subperiosteal cortex, where the highest loading-related strains are experienced...
  9. ncbi request reprint Determinants of the size of incident vertebral deformities in European men and women in the sixth to ninth decades of age: the European Prospective Osteoporosis Study (EPOS)
    J Reeve
    Department of Medicine, Addenbrooke s Hospital, Cambridge, United Kingdom
    J Bone Miner Res 18:1664-73. 2003
    ..Subjects with bi-concave or crush fractures at baseline had a 2-fold increase in incident fracture size and thus increased risk of a disabling future fracture...
  10. ncbi request reprint Improving risk assessment: hip geometry, bone mineral distribution and bone strength in hip fracture cases and controls. The EPOS study. European Prospective Osteoporosis Study
    N J Crabtree
    University Department of Medicine, University of Cambridge, UK
    Osteoporos Int 13:48-54. 2002
    ..HSA might prove to be a valuable enhancement of DXA densitometry in clinical practice and its use could justify a more proactive approach to identifying women at high risk of hip fracture in the community...
  11. ncbi request reprint Determinants of incident vertebral fracture in men and women: results from the European Prospective Osteoporosis Study (EPOS)
    D K Roy
    ARC Epidemiology Unit, University of Manchester, Manchester, UK
    Osteoporos Int 14:19-26. 2003
    ..The important biological mechanisms underlying vertebral fracture risk need to be explored using new investigational strategies...
  12. ncbi request reprint Falls explain between-center differences in the incidence of limb fracture across Europe
    D K Roy
    ARC Epidemiology Unit, University of Manchester, UK
    Bone 31:712-7. 2002
    ..Given the constraints inherent in such an analysis, in men and women aged 50-79 years, variation in fall rates could explain a significant proportion of the between-center variation in the incidence of limb fracture across Europe...
  13. ncbi request reprint Is the predictive power of previous fractures for new spine and non-spine fractures associated with biochemical evidence of altered bone remodelling? The EPOS study. European Prospective Osteoporosis Study
    P Vergnaud
    U INSERM 403, Lyon, France
    Clin Chim Acta 322:121-32. 2002
    ..6 - 12-fold even after adjusting for BMD. We examined the possibility that biochemical marker levels were associated with this unexplained BMD-independent element of fracture risk...
  14. ncbi request reprint Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial
    P J Meunier
    Hopital Edouard Herriot, 69437 Lyon, France
    J Clin Endocrinol Metab 87:2060-6. 2002
    ..All tested doses were well tolerated; the 2 g/d dose was considered to offer the best combination of efficacy and safety. In conclusion, SR therapy increased vertebral BMD and reduced the incidence of vertebral fractures...
  15. ncbi request reprint Beneficial effect of liver transplantation on bone mineral density in small infants with cholestasis
    J Pawłowska
    Children s Memorial Health Institute, Warsaw, Poland
    Transplant Proc 36:1479-80. 2004
    ..The serum levels of phosphorus and 1-25(OH)2D3 as well as total bone mass density and Cole index were significantly increased after liver transplantation...
  16. ncbi request reprint Editorial
    P D Delmas
    J Musculoskelet Neuronal Interact 5:105-9. 2005
  17. ncbi request reprint Incidence of limb fracture across Europe: results from the European Prospective Osteoporosis Study (EPOS)
    A A Ismail
    ARC Epidemiology Unit, University of Manchester, Manchester, UK
    Osteoporos Int 13:565-71. 2002
    ..There are substantial differences in the descriptive epidemiology of limb fracture by region and gender...
  18. ncbi request reprint Prevalent vertebral deformity predicts incident hip though not distal forearm fracture: results from the European Prospective Osteoporosis Study
    A A Ismail
    ARC Epidemiology Unit, University of Manchester, UK
    Osteoporos Int 12:85-90. 2001
    ..In summary, prevalent radiographic vertebral deformities in women are a strong predictor of hip fracture, and to a lesser extent humerus and 'other' limb fractures; however, they do not predict distal forearm fractures...