S J Lolait

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis
    Georgina G J Hazell
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, School of Clinical Sciences, University of Bristol, Whitson Street, Bristol BS1 3NY, UK
    Front Neuroendocrinol 33:45-66. 2012
  2. pmc Attenuated stress response to acute lipopolysaccharide challenge and ethanol administration in vasopressin V1b receptor knockout mice
    S J Lolait
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, University of Bristol, Bristol, UK
    J Neuroendocrinol 19:543-51. 2007
  3. pmc The hypothalamic-pituitary-adrenal axis response to stress in mice lacking functional vasopressin V1b receptors
    Stephen J Lolait
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, Dorothy Hodgkin Building, University of Bristol, Whitson Street, Bristol BS1 3NY, United Kingdom
    Endocrinology 148:849-56. 2007
  4. doi request reprint Pituitary-adrenal response to acute and repeated mild restraint, forced swim and change in environment stress in arginine vasopressin receptor 1b knockout mice
    L Q Stewart
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, University of Bristol, Bristol, UK
    J Neuroendocrinol 20:597-605. 2008
  5. ncbi request reprint Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues
    A M O'Carroll
    Dorothy Crowfoot Hodgkin Laboratories, University Research Centre for Neuroendocrinology, University of Bristol, UK
    Biochim Biophys Acta 1492:72-80. 2000
  6. pmc Stress-dependent and gender-specific neuroregulatory roles of the apelin receptor in the hypothalamic-pituitary-adrenal axis response to acute stress
    M J F Newson
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
    J Endocrinol 216:99-109. 2013
  7. doi request reprint The vasopressin V1b receptor modulates plasma corticosterone responses to dehydration-induced stress
    E M Roberts
    School of Clinical Sciences, Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK
    J Neuroendocrinol 23:12-9. 2011
  8. ncbi request reprint Regulation of rat APJ receptor messenger ribonucleic acid expression in magnocellular neurones of the paraventricular and supraopric nuclei by osmotic stimuli
    A M O'Carroll
    University Research Centre for Neuroendocrinology, University of Bristol, Bristol, UK
    J Neuroendocrinol 15:661-6. 2003
  9. doi request reprint The role of the arginine vasopressin Avp1b receptor in the acute neuroendocrine action of antidepressants
    Lesley Q Stewart
    University of Bristol, Whitson Street, Bristol BS1 3NY, UK
    Psychoneuroendocrinology 33:405-15. 2008
  10. pmc The effects of apelin on hypothalamic-pituitary-adrenal axis neuroendocrine function are mediated through corticotrophin-releasing factor- and vasopressin-dependent mechanisms
    Michael J F Newson
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK
    J Endocrinol 202:123-9. 2009

Collaborators

Detail Information

Publications19

  1. pmc G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis
    Georgina G J Hazell
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, School of Clinical Sciences, University of Bristol, Whitson Street, Bristol BS1 3NY, UK
    Front Neuroendocrinol 33:45-66. 2012
    ..We also present some aspects of the regulation and known roles of GPCRs in PVN/SON, which are likely complemented by the activity of 'orphan' GPCRs...
  2. pmc Attenuated stress response to acute lipopolysaccharide challenge and ethanol administration in vasopressin V1b receptor knockout mice
    S J Lolait
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, University of Bristol, Bristol, UK
    J Neuroendocrinol 19:543-51. 2007
    ..Our results clearly suggest that Avpr1b plays a significant role in the HPA axis response to acute immune stress and EtOH intoxication...
  3. pmc The hypothalamic-pituitary-adrenal axis response to stress in mice lacking functional vasopressin V1b receptors
    Stephen J Lolait
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, Dorothy Hodgkin Building, University of Bristol, Whitson Street, Bristol BS1 3NY, United Kingdom
    Endocrinology 148:849-56. 2007
    ..The data suggest that the Avpr1b is required for the normal pituitary and adrenal response to some acute stressful stimuli and is necessary only for a normal ACTH response during chronic stress...
  4. doi request reprint Pituitary-adrenal response to acute and repeated mild restraint, forced swim and change in environment stress in arginine vasopressin receptor 1b knockout mice
    L Q Stewart
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, University of Bristol, Bristol, UK
    J Neuroendocrinol 20:597-605. 2008
    ..Furthermore, the normal corticosterone response to repeated exposure to change in environment stress also requires the Avpr1b to drive HPA axis responsiveness...
  5. ncbi request reprint Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues
    A M O'Carroll
    Dorothy Crowfoot Hodgkin Laboratories, University Research Centre for Neuroendocrinology, University of Bristol, UK
    Biochim Biophys Acta 1492:72-80. 2000
    ..This hypothalamic distribution offers a possible specific role of this receptor in mediating neuroendocrine responses in the CNS...
  6. pmc Stress-dependent and gender-specific neuroregulatory roles of the apelin receptor in the hypothalamic-pituitary-adrenal axis response to acute stress
    M J F Newson
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
    J Endocrinol 216:99-109. 2013
    ..These data indicate that APJ has a role in regulation of the HPA axis response to some acute stressors and has a gender-specific function in peripheral immune activation of the HPA axis...
  7. doi request reprint The vasopressin V1b receptor modulates plasma corticosterone responses to dehydration-induced stress
    E M Roberts
    School of Clinical Sciences, Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK
    J Neuroendocrinol 23:12-9. 2011
    ..These data suggest that, although the vasopressin V1bR is not required for normal HNS function, it is necessary for a full HPA-axis response to the osmotic stress of WD...
  8. ncbi request reprint Regulation of rat APJ receptor messenger ribonucleic acid expression in magnocellular neurones of the paraventricular and supraopric nuclei by osmotic stimuli
    A M O'Carroll
    University Research Centre for Neuroendocrinology, University of Bristol, Bristol, UK
    J Neuroendocrinol 15:661-6. 2003
    ..These data verify a role for APJ receptors in body fluid regulation and suggest a role for apelin in the regulation of vasopressin-containing neurones via a local autocrine/paracrine action of the peptide...
  9. doi request reprint The role of the arginine vasopressin Avp1b receptor in the acute neuroendocrine action of antidepressants
    Lesley Q Stewart
    University of Bristol, Whitson Street, Bristol BS1 3NY, UK
    Psychoneuroendocrinology 33:405-15. 2008
    ....
  10. pmc The effects of apelin on hypothalamic-pituitary-adrenal axis neuroendocrine function are mediated through corticotrophin-releasing factor- and vasopressin-dependent mechanisms
    Michael J F Newson
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK
    J Endocrinol 202:123-9. 2009
    ..Together, these data confirm that the in vivo effects of apelin on hypothalamic-pituitary-adrenal neuroendocrine function appear to be mediated through both CRF- and AVP-dependent mechanisms...
  11. ncbi request reprint APJ receptor mRNA expression in the rat hypothalamic paraventricular nucleus: regulation by stress and glucocorticoids
    A M O'Carroll
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, Dorothy Hodgkin Building, University of Bristol, Bristol, UK
    J Neuroendocrinol 15:1095-101. 2003
    ....
  12. ncbi request reprint Transcriptional regulation of the rat apelin receptor gene: promoter cloning and identification of an Sp1 site necessary for promoter activity
    Anne Marie O'Carroll
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, Dorothy Hodgkin Building, Whitson Street, University of Bristol, Bristol BS1 3NY, UK
    J Mol Endocrinol 36:221-35. 2006
    ..Promoter regulation by the cAMP-dependent signal cascade was also shown...
  13. doi request reprint The transcriptome of the medullary area postrema: the thirsty rat, the hungry rat and the hypertensive rat
    Charles C T Hindmarch
    The Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol BS1 3NY, UK
    Exp Physiol 96:495-504. 2011
    ..Finally, analysis of these 'hypertension-related' elements revealed genes that are involved in the regulation of both blood pressure and immune function and as such are excellent targets for further study...
  14. pmc Vasopressin potentiates corticotropin-releasing hormone-induced insulin release from mouse pancreatic beta-cells
    Anne Marie O'Carroll
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology LINE, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
    J Endocrinol 197:231-9. 2008
    ..This is the first example of a possible interplay between the AVP and CRH systems outside of the hypothalamic-pituitary-adrenal axis...
  15. doi request reprint Stimulus-specific neuroendocrine responses to osmotic challenges in apelin receptor knockout mice
    E M Roberts
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK
    J Neuroendocrinol 22:301-8. 2010
    ..These findings further implicate the apelinergic system in mechanisms controlling fluid homeostasis, particularly at a neuroendocrine level, and suggest stimulus-specific involvement in vasopressinergic activity...
  16. pmc Attenuated stress response to acute restraint and forced swimming stress in arginine vasopressin 1b receptor subtype (Avpr1b) receptor knockout mice and wild-type mice treated with a novel Avpr1b receptor antagonist
    J A Roper
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK
    J Neuroendocrinol 22:1173-80. 2010
    ....
  17. pmc Abnormal fluid homeostasis in apelin receptor knockout mice
    Emma M Roberts
    Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol BS1 3NY, UK
    J Endocrinol 202:453-62. 2009
    ..These findings demonstrate a physiological role for APJ in mechanisms of water intake and fluid retention and suggest an anti-diuretic effect of apelin in vivo...
  18. pmc Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues
    Georgina G J Hazell
    LINE, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, UK
    J Endocrinol 202:223-36. 2009
    ..The distribution of GPR30 is distinct from the other traditional ERs and offers an additional way in which oestrogen may mediate its effects in numerous brain regions and endocrine systems in the rodent...
  19. ncbi request reprint Social motivation is reduced in vasopressin 1b receptor null mice despite normal performance in an olfactory discrimination task
    Scott R Wersinger
    Section on Neural Gene Expression, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892, USA
    Horm Behav 46:638-45. 2004
    ..We propose that the V1bR plays an important role in social motivation, perhaps by coupling the processing, integration, and/or interpretation of chemosensory cues with the appropriate behavioral response...