D N Lobo

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. ncbi request reprint How perioperative fluid balance influences postoperative outcomes
    Dileep N Lobo
    Division of Gastrointestinal Surgery, Section of Surgery, E Floor, West Block, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Best Pract Res Clin Anaesthesiol 20:439-55. 2006
  2. doi request reprint The history of 0.9% saline
    Sherif Awad
    Division of Gastrointestinal Surgery, Wolfson Digestive Diseases Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Clin Nutr 27:179-88. 2008
  3. doi request reprint The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials
    Krishna K Varadhan
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2 UH, UK
    Clin Nutr 29:434-40. 2010
  4. pmc Intestinal ischemia following laparoscopic surgery: a case series
    Waleed Al-Khyatt
    Division of Surgery, School of Graduate Entry Medicine and Health, University of Nottingham, Royal Derby Hospital, Uttoxetter Road, Derby DE22 3DT, UK
    J Med Case Rep 7:25. 2013
  5. pmc Calpain system protein expression in carcinomas of the pancreas, bile duct and ampulla
    Sarah J Storr
    Academic Oncology, University of Nottingham, School of Molecular Medical Sciences, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, UK
    BMC Cancer 12:511. 2012
  6. doi request reprint Three cases of concomitant intraductal papillary mucinous neoplasm and pancreatic neuroendocrine tumour
    Nilanjana Tewari
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre National Institute for Health Research Biomedical Research Unit, University of Nottingham, Queen s Medical Centre Nottingham, United Kingdom
    JOP 14:423-7. 2013
  7. pmc Immunohistochemical expression of mitochondrial membrane complexes (MMCs) I, III, IV and V in malignant and benign periampullary epithelium: a potential target for drug therapy of periampullary cancer?
    Mark M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Cancer 10:80. 2010
  8. pmc Complete absence of M2-pyruvate kinase expression in benign pancreatic ductal epithelium and pancreaticobiliary and duodenal neoplasia
    Mark M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Cancer 9:327. 2009
  9. doi request reprint Effect of volume loading with 1 liter intravenous infusions of 0.9% saline, 4% succinylated gelatine (Gelofusine) and 6% hydroxyethyl starch (Voluven) on blood volume and endocrine responses: a randomized, three-way crossover study in healthy volunteers
    Dileep N Lobo
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Crit Care Med 38:464-70. 2010
  10. ncbi request reprint Fluid, electrolytes and nutrition: physiological and clinical aspects
    Dileep N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Proc Nutr Soc 63:453-66. 2004

Collaborators

Detail Information

Publications59

  1. ncbi request reprint How perioperative fluid balance influences postoperative outcomes
    Dileep N Lobo
    Division of Gastrointestinal Surgery, Section of Surgery, E Floor, West Block, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Best Pract Res Clin Anaesthesiol 20:439-55. 2006
    ....
  2. doi request reprint The history of 0.9% saline
    Sherif Awad
    Division of Gastrointestinal Surgery, Wolfson Digestive Diseases Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Clin Nutr 27:179-88. 2008
    ..We aimed to trace the historical origins of 0.9% saline, how it came to be used so commonly today, and to consider whether its continued use can be justified...
  3. doi request reprint The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials
    Krishna K Varadhan
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2 UH, UK
    Clin Nutr 29:434-40. 2010
    ..The objective of this meta-analysis was to study the differences in outcomes in patients undergoing major elective open colorectal surgery within an ERAS pathway and those treated with conventional perioperative care...
  4. pmc Intestinal ischemia following laparoscopic surgery: a case series
    Waleed Al-Khyatt
    Division of Surgery, School of Graduate Entry Medicine and Health, University of Nottingham, Royal Derby Hospital, Uttoxetter Road, Derby DE22 3DT, UK
    J Med Case Rep 7:25. 2013
    ..abstract:..
  5. pmc Calpain system protein expression in carcinomas of the pancreas, bile duct and ampulla
    Sarah J Storr
    Academic Oncology, University of Nottingham, School of Molecular Medical Sciences, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, UK
    BMC Cancer 12:511. 2012
    ..Pancreatic cancer, including cancer of the ampulla of Vater and bile duct, is very aggressive and has a poor five year survival rate; improved methods of patient stratification are required...
  6. doi request reprint Three cases of concomitant intraductal papillary mucinous neoplasm and pancreatic neuroendocrine tumour
    Nilanjana Tewari
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre National Institute for Health Research Biomedical Research Unit, University of Nottingham, Queen s Medical Centre Nottingham, United Kingdom
    JOP 14:423-7. 2013
    ..The association of IPMN and neuroendocrine tumours of the pancreas has been reported previously but is exceedingly rare...
  7. pmc Immunohistochemical expression of mitochondrial membrane complexes (MMCs) I, III, IV and V in malignant and benign periampullary epithelium: a potential target for drug therapy of periampullary cancer?
    Mark M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Cancer 10:80. 2010
    ..Therefore, we studied the expression profile of MMCs I, III, IV and V in periampullary cancers, reactive pancreatitis, normal pancreas and chronic pancreatitis...
  8. pmc Complete absence of M2-pyruvate kinase expression in benign pancreatic ductal epithelium and pancreaticobiliary and duodenal neoplasia
    Mark M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Cancer 9:327. 2009
    ..We aimed to characterise the immunohistochemical expression of M2-PK in archived specimens of pancreaticobiliary and duodenal cancers, premalignant lesions, chronic pancreatitis, and normal pancreas...
  9. doi request reprint Effect of volume loading with 1 liter intravenous infusions of 0.9% saline, 4% succinylated gelatine (Gelofusine) and 6% hydroxyethyl starch (Voluven) on blood volume and endocrine responses: a randomized, three-way crossover study in healthy volunteers
    Dileep N Lobo
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Crit Care Med 38:464-70. 2010
    ..9% saline, Gelofusine (4% succinylated gelatin in 0.7% saline, weight-average molecular weight 30 kD), and Voluven (6% hydroxyethyl starch in 0.9% saline, weight-average molecular weight 130 kD) in healthy volunteers...
  10. ncbi request reprint Fluid, electrolytes and nutrition: physiological and clinical aspects
    Dileep N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Proc Nutr Soc 63:453-66. 2004
    ..It is also of importance when prescribing artificial nutrition and should be given the same careful consideration as other nutritional and pharmacological needs...
  11. pmc Peri-operative fluid and electrolyte management: a survey of consultant surgeons in the UK
    D N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Ann R Coll Surg Engl 84:156-60. 2002
    ..Current peri-operative fluid and electrolyte management in the UK may be suboptimal. We assessed the attitudes of consultant surgeons to fluid and electrolyte prescribing and gathered suggestions for improvement in education on the subject...
  12. ncbi request reprint Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial
    Dileep N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Lancet 359:1812-8. 2002
    ..We aimed to determine the effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection in human beings...
  13. ncbi request reprint Reproducibility and normal ranges for gastric emptying in normal volunteers using a test meal designed for post-operative patients
    D N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Nucl Med Commun 23:97-101. 2002
    ..The modified test meal gave reproducible results in healthy volunteers; however, solid phase emptying was significantly faster than that of the bulkier test meal in historical subjects...
  14. ncbi request reprint Dilution and redistribution effects of rapid 2-litre infusions of 0.9% (w/v) saline and 5% (w/v) dextrose on haematological parameters and serum biochemistry in normal subjects: a double-blind crossover study
    D N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham NG72UH, UK
    Clin Sci (Lond) 101:173-9. 2001
    ..Changes in bioelectrical impedance may reflect the electrolyte content rather than the volume of the infusate, and may be unreliable for clinical purposes...
  15. ncbi request reprint Early postoperative jejunostomy feeding with an immune modulating diet in patients undergoing resectional surgery for upper gastrointestinal cancer: a prospective, randomized, controlled, double-blind study
    Dileep N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, E Floor, West Block, Nottingham NG7 2UH, UK
    Clin Nutr 25:716-26. 2006
    ..The aim of this study was to determine whether early postoperative immune modulating jejunostomy feeding results in reduced infective complications in patients undergoing resectional surgery for upper gastrointestinal cancer...
  16. doi request reprint Gastric emptying of three liquid oral preoperative metabolic preconditioning regimens measured by magnetic resonance imaging in healthy adult volunteers: a randomised double-blind, crossover study
    Dileep N Lobo
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Clin Nutr 28:636-41. 2009
    ..We compared the gastric emptying of two types of preoperative metabolic preconditioning drinks [Oral Nutritional Supplement (ONS) (Fresenius Kabi, Germany) and preOp (Nutricia Clinical Care, UK)] in healthy volunteers...
  17. pmc An audit of emergency abdominal aortic aneurysm repair to establish the necessity for an emergency vascular surgical rota
    D N Lobo
    Derbyshire Royal Infirmary, Derby, UK
    Ann R Coll Surg Engl 81:156-60. 1999
    ..The mortality figures compare favourably with other published series. As the results of the two groups were similar, there is currently no need for vascular surgeons to be routinely available for acute AAA surgery at our hospital...
  18. ncbi request reprint Body water compartment measurements: a comparison of bioelectrical impedance analysis with tritium and sodium bromide dilution techniques
    J A Simpson
    Section of Surgery, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH, UK
    Clin Nutr 20:339-43. 2001
    ..CONCLUSION: TBW measurements obtained using the single frequency BIA device were more accurate than those obtained using the dual frequency BIA device. Dual frequency BIA provided a reasonably accurate estimate of ECW...
  19. ncbi request reprint The effect of an oral glucose load on sodium and water excretion after rapid intravenous infusion of 0.9% (w/v) saline
    D N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Clin Nutr 22:255-9. 2003
    ..To test this, we studied the effects of an oral glucose load on urinary sodium and water excretion and serum biochemistry in response to a 2l intravenous infusion of 0.9% saline in normal subjects...
  20. doi request reprint Effects of an intraoperative infusion of 4% succinylated gelatine (Gelofusine(R)) and 6% hydroxyethyl starch (Voluven(R)) on blood volume
    S Awad
    Division of Gastrointestinal Surgery, E Floor, West Block, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Br J Anaesth 109:168-76. 2012
    ..7% saline, weight-average molecular weight (MWw) 30 kDa] and Voluven(®) (6% hydroxyethyl starch in 0.9% saline, MWw 130 kDa) in the presence of increased capillary permeability...
  21. ncbi request reprint Audit of acute pancreatitis management: a tale of two hospitals
    M G Dube
    Division of Gastrointestinal Surgery, University Hospital, Queen's Medical Centre, Nottingham, UK
    J R Coll Surg Edinb 46:292-6. 2001
    ..It remains to be seen whether new measures to aid compliance with guidelines will result in improvement in morbidity and mortality...
  22. ncbi request reprint Problems with solutions: drowning in the brine of an inadequate knowledge base
    D N Lobo
    Department of Public Health Medicine and Epidemiology, Section of Surgery, Nottingham, UK
    Clin Nutr 20:125-30. 2001
    ..Undergraduate and postgraduate training in this basic patient management skill needs improvement, with particular emphasis on the practical aspects...
  23. ncbi request reprint Relationships between structural and functional measures of nutritional status in a normally nourished population
    S T Hornby
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Clin Nutr 24:421-6. 2005
    ..This study aims to measure in normal subjects the relationship between anthropometric measurements, voluntary muscle strength by hand grip dynamometry and respiratory muscle function by peak expiratory flow rate...
  24. ncbi request reprint (Ab)normal saline and physiological Hartmann's solution: a randomized double-blind crossover study
    Fiona Reid
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Clin Sci (Lond) 104:17-24. 2003
    ..9% saline than after Hartmann's solution, due possibly to the more physiological [Na(+)]/[Cl(-)] ratio in Hartmann's solution (1.18:1) than in saline (1:1) and to the hyperchloraemia caused by saline...
  25. pmc Debate: Albumin administration should not be avoided
    S P Allison
    Clinical Nutrition Unit, University Hospital, Queen s Medical Centre, Nottingham, UK
    Crit Care 4:147-50. 2000
    ..We argue for the use of salt-poor albumin solutions in this situation and conclude that, on current evidence, the assertion that albumin should be avoided in all situations is irrational and untenable...
  26. ncbi request reprint The 'two-week' target for the diagnosis of pancreatic carcinoma: an achievable aim?
    A D Gilliam
    Section of Surgery, Queen s Medical Centre, University Hospital, NG7 2UH, Nottingham, UK
    Eur J Surg Oncol 29:575-9. 2003
    ..The aim of this study was to evaluate the current diagnostic process for patients with pancreatic cancer in a University teaching hospital and to determine whether the 'two-week' target for rapid assessment was being met...
  27. pmc Acute appendicitis--a benign disease?
    J Simpson
    Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Ann R Coll Surg Engl 90:313-6. 2008
    ..Most patients recover quickly but a minority can suffer postoperative complications. This case-note review was undertaken to assess the frequency of these complications...
  28. doi request reprint The effects of bolus and continuous nasogastric feeding on gastro-oesophageal reflux and gastric emptying in healthy volunteers: a randomised three-way cross-over study
    T E Bowling
    Department of Gastroenterology, Nottingham University Hospitals, Nottingham NG7 2UH, UK
    Proc Nutr Soc 67:E110. 2008
  29. doi request reprint Mucins and CD56 as markers of tumour invasion and prognosis in periampullary cancer
    M M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, National Institute for Health Research Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Br J Surg 97:1269-78. 2010
    ..This study investigated the association of mucins and cluster of differentiation (CD) 56 with vascular and perineural invasion and survival in patients with periampullary cancer...
  30. ncbi request reprint A practical posture for hand grip dynamometry in the clinical setting
    T E Hillman
    Section of Surgery, Queen s Medical Centre, University Hospital, Nottingham NG7 2UH, UK
    Clin Nutr 24:224-8. 2005
    ..We therefore examined the systematic difference between different postures in order to establish a methodology that is clinically relevant, easy to perform and reproducible...
  31. ncbi request reprint Gallstone ileus: diagnostic pitfalls and therapeutic successes
    D N Lobo
    Department of Surgery, Nottingham City Hospital, UK
    J Clin Gastroenterol 30:72-6. 2000
    ..No patient had biliary symptoms on follow-up. Gallstone ileus is a difficult clinical and radiologic diagnosis. Enterolithotomy alone is adequate treatment in the elderly, and subsequent cholecystectomy is not mandatory...
  32. ncbi request reprint Fluid and electrolytes in the clinical setting
    Dileep N Lobo
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Nestle Nutr Workshop Ser Clin Perform Programme 9:187-198; discussion 198-203. 2004
  33. doi request reprint CD24 is upregulated in inflammatory bowel disease and stimulates cell motility and colony formation
    Mohamed A H Ahmed
    Division of Pathology, School of Molecular Medical Sciences, Queen s Medical Centre Campus, University of Nottingham, UK
    Inflamm Bowel Dis 16:795-803. 2010
    ..We investigated whether CD24 (reportedly a stem cell marker and adhesion molecule) was expressed in regenerative mucosa in inflammatory bowel disease (IBD) and whether it could be functionally relevant...
  34. doi request reprint Cellular mechanisms underlying the protective effects of preoperative feeding: a randomized study investigating muscle and liver glycogen content, mitochondrial function, gene and protein expression
    Sherif Awad
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, United Kingdom
    Ann Surg 252:247-53. 2010
    ....
  35. doi request reprint Prediction, prevention and management of postresection liver failure
    J S Hammond
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre National Institute of Health Research Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Br J Surg 98:1188-200. 2011
    ..However, there is no unified definition, the pathophysiology is understood poorly and there are few controlled trials to optimize its management. The aim of this review article is to present strategies to predict, prevent and manage PLF...
  36. doi request reprint Prospective randomized trial using cost-utility analysis of early versus delayed laparoscopic cholecystectomy for acute gallbladder disease
    D A L Macafee
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Br J Surg 96:1031-40. 2009
    ..This randomized controlled trial compared the cost-utility of early laparoscopic cholecystectomy with that for conventional management of newly diagnosed acute gallbladder disease...
  37. ncbi request reprint Percutaneous biliary metal wall stenting in malignant obstructive jaundice
    Adrian A Indar
    Section of Surgery, University Hospital Nottingham NHS Trust, Nottingham, UK
    Eur J Gastroenterol Hepatol 15:915-9. 2003
    ..Most patients with advanced stage malignant obstructive jaundice will be suitable for palliation only. Metallic stents are safe, effective and minimally invasive...
  38. doi request reprint The effects of bolus and continuous nasogastric feeding on gastro-oesophageal reflux and gastric emptying in healthy volunteers: a randomised three-way crossover pilot study
    Tim E Bowling
    Department of Gastroenterology, Wolfson Digestive Diseases Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    Clin Nutr 27:608-13. 2008
    ..We aimed to measure gastric emptying time and quantify gastro-oesophageal reflux in healthy volunteers given a liquid feed via an oral bolus (OB), a nasogastric tube bolus (TB) and a nasogastric tube drip (TD)...
  39. doi request reprint Predictive value of tumor proliferative indices in periampullary cancers: Ki-67, mitotic activity index (MI) and volume corrected mitotic index (M/V) using tissue microarrays
    Mark M Aloysius
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    World J Surg 34:2115-21. 2010
    ..The purpose of the study was to assess these indices on tissue microarray (TMA) sections constructed from patients with periampullary cancers and study their association with clinicopathological variables...
  40. doi request reprint Retained surgical sponges, needles and instruments
    D Hariharan
    Nottingham University Hospitals NHS Trust, Queen s Medical Centre, Nottingham, UK
    Ann R Coll Surg Engl 95:87-92. 2013
    ..The aim of this review was to elucidate the extent of the problem of RSI and to identify preventative strategies...
  41. pmc Tumour regression and ERCC1 nuclear protein expression predict clinical outcome in patients with gastro-oesophageal cancer treated with neoadjuvant chemotherapy
    K R Fareed
    Laboratory of Molecular Oncology, Academic Unit of Oncology, School of Molecular Medical Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK
    Br J Cancer 102:1600-7. 2010
    ..In this study we profiled key DNA repair and damage signalling factors and correlated them with clinicopathological outcomes, including TRG response...
  42. doi request reprint Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer
    A Albasri
    Division of Pathology, Nottingham University, Nottingham, UK
    Oncogene 30:2997-3002. 2011
    ..002). We conclude that Cten expression is of prognostic significance in CRC, and we delineate a Cten-ILK pathway controlling cell motility and possibly promoting metastasis...
  43. ncbi request reprint Current practice of emergency vagotomy and Helicobacter pylori eradication for complicated peptic ulcer in the United Kingdom
    A D Gilliam
    Section of Surgery, E Floor, West Block, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Br J Surg 90:88-90. 2003
    ..The aim was to assess the current opinion of surgeons, by subspecialty, towards vagotomy and the practice of Helicobacter pylori testing, treatment and follow-up, in patients with bleeding or perforated duodenal ulcer...
  44. doi request reprint Comparison of lateral thermal spread using monopolar and bipolar diathermy, the Harmonic Scalpel and the Ligasure
    P A Sutton
    Division of Gastrointestinal Surgery, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Br J Surg 97:428-33. 2010
    ..Electrosurgery for dissection and haemostasis should be associated with minimal thermal spread to surrounding tissues. This study investigated lateral thermal spread following ex vivo application of four commonly utilized instruments...
  45. ncbi request reprint Pancreaticoduodenectomy with a "twist": the challenges of pancreatic resection in the presence of situs inversus totalis and situs ambiguus
    D A L Macafee
    Division of Gastrointestinal Surgery, Section of Surgery, E Floor, West Block, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Eur J Surg Oncol 33:524-7. 2007
  46. doi request reprint Enhanced recovery after surgery: the future of improving surgical care
    Krishna K Varadhan
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Crit Care Clin 26:527-47, x. 2010
    ..They also provide clear guidance to all members of the clinical team...
  47. doi request reprint The effects of fasting and refeeding with a 'metabolic preconditioning' drink on substrate reserves and mononuclear cell mitochondrial function
    Sherif Awad
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Clin Nutr 29:538-44. 2010
    ....
  48. ncbi request reprint Some interactions between gastrointestinal function and fluid and electrolyte homeostasis
    David Al Macafee
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Curr Opin Clin Nutr Metab Care 8:197-203. 2005
    ..The purpose of this review is to highlight some recent literature describing these interactions against a background of fluid and electrolyte physiology in normal and disease states...
  49. ncbi request reprint Fluid and electrolytes in the elderly
    Simon P Allison
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Curr Opin Clin Nutr Metab Care 7:27-33. 2004
    ....
  50. doi request reprint Fluid and electrolyte balance: the impact of goal directed teaching
    Sherif Awad
    Division of Gastrointestinal Surgery, Wolfson Digestive Diseases Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Clin Nutr 27:473-8. 2008
    ..We aimed to determine if a structured workshop on fluid and electrolyte balance for junior surgical trainees led to an improvement in knowledge on the subject and to evaluate the perceived helpfulness of such a workshop...
  51. ncbi request reprint EUS-guided core biopsy for pseudopapillary tumor of the pancreas
    Mark M Aloysius
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham, UK
    Gastrointest Endosc 63:155-6. 2006
  52. ncbi request reprint Heterotopic pancreas in the spleen: malignant degeneration to mucinous cystadenocarcinoma
    Pasha J Nisar
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Eur J Gastroenterol Hepatol 14:793-6. 2002
    ....
  53. doi request reprint Vacuum-assisted closure of postoperative abdominal wounds: a prospective study
    Sriram Subramonia
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    World J Surg 33:931-7. 2009
    ..We aimed to study outcome in patients with an open abdomen in whom the abdominal vacuum-assisted closure system (V.A.C.((R)) Therapy()) was used to provide temporary cover and achieve wound closure...
  54. doi request reprint Short-term starvation and mitochondrial dysfunction - a possible mechanism leading to postoperative insulin resistance
    Sherif Awad
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Clin Nutr 28:497-509. 2009
    ..The metabolic consequences of preoperative starvation and carbohydrate loading and mechanisms linking insulin resistance to impaired mitochondrial function are discussed...
  55. pmc Recent developments in diagnosis of pancreatic cancer
    Arjun S Takhar
    Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH
    BMJ 329:668-73. 2004
  56. doi request reprint Expression of key hypoxia sensing prolyl-hydroxylases PHD1, -2 and -3 in pancreaticobiliary cancer
    Lucy Gossage
    Laboratory of Molecular Oncology, Academic Unit of Oncology, Faculty of Medicine and Health Sciences, School of Molecular Medical Sciences, University of Nottingham, Nottingham, UK
    Histopathology 56:908-20. 2010
    ..The aim was to investigate whether key hypoxia sensing prolyl hydroxylases PHD1, PHD2 and PHD3 are dysregulated in pancreaticobiliary cancers, and to evaluate their potential clinical significance...
  57. pmc Laparoscopic cholecystectomy in a patient with myotonic dystrophy
    Arjun S Takhar
    Section of Surgery, Department of Anaesthetics, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    J R Soc Med 97:284-5. 2004
  58. ncbi request reprint Carbon dioxide narcosis and grand mal seizure complicating laparoscopic herniorrhaphy
    Quentin M Nunes
    Section of Surgery, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Surg Laparosc Endosc Percutan Tech 17:52-3. 2007
    ..The possible mechanisms are discussed...
  59. doi request reprint The pedicle effect and direct coupling: delayed thermal injuries to the bile duct after laparoscopic cholecystectomy
    David J Humes
    Nottingham University Hospitals, Queen s Medical Centre, England
    Arch Surg 145:96-8. 2010
    ..We suggest that surgeons keep the use of monopolar diathermy to a minimum while dissecting near vital structures...